keyword
MENU ▼
Read by QxMD icon Read
search

Fat transfer

keyword
https://www.readbyqxmd.com/read/28333222/ivf-or-iui-as-first-line-treatment-in-unexplained-subfertility-the-conundrum-of-treatment-selection-markers
#1
R I Tjon-Kon-Fat, P Tajik, M H Zafarmand, A J Bensdorp, P M M Bossuyt, G J E Oosterhuis, R van Golde, S Repping, M D A Lambers, E Slappendel, D Perquin, M J Pelinck, J Gianotten, J W M Maas, M J C Eijkemans, F van der Veen, B W Mol, M van Wely
STUDY QUESTION: Are there treatment selection markers that could aid in identifying couples, with unexplained or mild male subfertility, who would have better chances of a healthy child with IVF with single embryo transfer (IVF-SET) than with IUI with ovarian stimulation (IUI-OS)? SUMMARY ANSWER: We did not find any treatment selection markers that were associated with better chances of a healthy child with IVF-SET instead of IUI-OS in couples with unexplained or mild male subfertility...
February 24, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28331053/acetate-dose-dependently-stimulates-milk-fat-synthesis-in-lactating-dairy-cows
#2
Natalie L Urrutia, Kevin J Harvatine
Background: Acetate is a short-chain fatty acid (FA) that is especially important to cows because it is the major substrate for de novo FA synthesis. However, the effect of acetate supply on mammary lipid synthesis is not clear.Objective: The objective of this experiment was to determine the effect of increasing acetate supply on milk fat synthesis in lactating dairy cows.Methods: Six multiparous lactating Holstein cows were randomly assigned to treatments in a replicated design to investigate the effect of acetate supply on milk fat synthesis...
March 22, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28302863/transfer-of-dysbiotic-gut-microbiota-has-beneficial-effects-on-host-liver-metabolism
#3
Simon Nicolas, Vincent Blasco-Baque, Audren Fournel, Jerome Gilleron, Pascale Klopp, Aurelie Waget, Franck Ceppo, Alysson Marlin, Roshan Padmanabhan, Jason S Iacovoni, François Tercé, Patrice D Cani, Jean-François Tanti, Remy Burcelin, Claude Knauf, Mireille Cormont, Matteo Serino
Gut microbiota dysbiosis has been implicated in a variety of systemic disorders, notably metabolic diseases including obesity and impaired liver function, but the underlying mechanisms are uncertain. To investigate this question, we transferred caecal microbiota from either obese or lean mice to antibiotic-free, conventional wild-type mice. We found that transferring obese-mouse gut microbiota to mice on normal chow (NC) acutely reduces markers of hepatic gluconeogenesis with decreased hepatic PEPCK activity, compared to non-inoculated mice, a phenotypic trait blunted in conventional NOD2 KO mice...
March 16, 2017: Molecular Systems Biology
https://www.readbyqxmd.com/read/28285647/diet-induced-obesity-has-an-influence-on-intrahepatic-t-cell-responses
#4
Pratibha Gaur, Marcin Cebula, Mathias Riehn, Upneet Hillebrand, Hansjörg Hauser, Dagmar Wirth
AIM: Obesity is accompanied with systemic inflammation and pre-conditions to severe alterations in liver environment and functions. So far, it remains elusive to which extent obesity modulates immune responses during hepatotropic virus infections as well as in autoimmune hepatitis. In this study we investigated the influence of obesity on the intrahepatic immune response, in particular on the function of CD8 T cells as the crucial players in clearance of virus infected hepatocytes. METHODS: We established high fat induced obesity in transgenic mouse models with hepatocyte specific expression of a model antigen (Ova)...
April 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28284064/aberrant-expression-of-microrna-induced-by-high-fructose-diet-implications-in-the-pathogenesis-of-hyperlipidemia-and-hepatic-insulin-resistance
#5
Neetu Sud, Hanyuan Zhang, Kaichao Pan, Xiao Cheng, Juan Cui, Qiaozhu Su
Fructose is a highly lipogenic sugar that can alter energy metabolism and trigger metabolic disorders. In the current study, microRNAs (miRNAs) altered by a high-fructose diet were comprehensively explored to elucidate their significance in the pathogenesis of chronic metabolic disorders. miRNA expression profiling using small noncoding RNA sequencing revealed that 19 miRNAs were significantly upregulated and 26 were downregulated in the livers of high-fructose-fed mice compared to chow-fed mice. Computational prediction and functional analysis identified 10 miRNAs, miR-19b-3p, miR-101a-3p, miR-30a-5p, miR-223-3p, miR-378a-3p, miR-33-5p, miR-145a-3p, miR-128-3p, miR-125b-5p and miR-582-3p, assembled as a regulatory network to potentially target key genes in lipid and lipoprotein metabolism and insulin signaling at multiple levels...
February 20, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28282788/berberine-inhibits-palmitate-induced-nlrp3-inflammasome-activation-by-triggering-autophagy-in-macrophages-a-new-mechanism-linking-berberine-to-insulin-resistance-improvement
#6
Hang Zhou, Lili Feng, Fang Xu, Yi Sun, Yuxiang Ma, Xiong Zhang, Hailiang Liu, Ge Xu, Xuefeng Wu, Yan Shen, Yang Sun, Xudong Wu, Qiang Xu
NLRP3 (Nod-like receptor family pyrin domain containing 3) inflammasome has been reported to contribute to obesity-induced inflammation and insulin resistance. However, there are few drugs targeting NLRP3 inflammasome for the treatment of insulin resistance. In the present study, we showed that berberine (BBR) significantly suppressed saturated fatty acid palmitate (PA)-induced NLRP3 inflammasome activation and interleukin-1β (IL-1β) release in macrophages, which was one of the most important mediators in the insulin sensitivity of adipose tissue...
March 6, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28280493/t-cells-specific-for-a-self-peptide-of-apob-100-exacerbate-aortic-atheroma-in-murine-atherosclerosis
#7
Michael K Shaw, Kevin Y Tse, Xiaoqing Zhao, Kathryn Welch, Daniel T Eitzman, Raghavendar R Thipparthi, Paul C Montgomery, Ryan Thummel, Harley Y Tse
On the basis of mouse I-A(b)-binding motifs, two sequences of the murine apolipoprotein B-100 (mApoB-100), mApoB-1003501-3515 (designated P3) and mApoB-100978-992 (designated P6), were found to be immunogenic. In this report, we show that P6 is also atherogenic. Immunization of Apoe(-/-) mice fed a high-fat diet (HFD) with P6 resulted in enhanced development of aortic atheroma as compared to control mice immunized with an irrelevant peptide MOG35-55 or with complete Freund's adjuvant alone. Adoptive transfer of lymph node cells from P6-immunized donor mice to recipients fed an HFD caused exacerbated aortic atheromas, correlating P6-primed cells with disease development...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28269161/bio-heat-transfer-model-of-electroconvulsive-therapy-effect-of-biological-properties-on-induced-temperature-variation
#8
Marilia M de Oliveira, Paul Wen, Tony Ahfock
A realistic human head model consisting of six tissue layers was modelled to investigate the behavior of temperature profile and magnitude when applying electroconvulsive therapy stimulation and different biological properties. The thermo-electrical model was constructed with the use of bio-heat transfer equation and Laplace equation. Three different electrode montages were analyzed as well as the influence of blood perfusion, metabolic heat and electric and thermal conductivity in the scalp. Also, the effect of including the fat layer was investigated...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28259941/consumption-of-policosanol-enhances-hdl-functionality-via-cetp-inhibition-and-reduces-blood-pressure-and-visceral-fat-in-young-and-middle-aged-subjects
#9
Jae-Yong Kim, Seong-Min Kim, Suk-Jeong Kim, Eun-Young Lee, Jae-Ryong Kim, Kyung-Hyun Cho
It is well-known that policosanol can improve serum lipid profiles, although the physiological mechanism is still unknown. Here, we investigated functional and structural changes in lipoproteins after consumption of policosanol. To investigate the physiological effect of policosanol, we analyzed serum parameters in young non-smoker (YN; n=7, 24.0±2.4 years), young smoker (YS; n=7, 26.3±1.5 years), and middle-aged subjects (MN; n=11, 52.5±9.8 years) who consumed policosanol daily (10 mg/day) for 8 weeks...
February 24, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28259071/epidural-lipomatosis-with-cauda-equina-syndrome-in-chronic-alcoholic-patient-a-case-report
#10
Sung-Soo Kim, Dong-Ju Lim
INTRODUCTION: Epidural lipomatosis of the lumbar spine is a rare condition, which is described as the accumulation of fat in the extradural territory. PRESENTATION OF CASE: We report the case of a 60-year-old, non-obese, and chronic alcoholic man who was transferred to our spine department with cauda equina syndrome (CES) for 4 months. On magnetic resonance imaging (MRI), spinal epidural lipomatosis (SEL) was confirmed in the multilevel lumbar lesion. A decompression surgery was performed and the patient recovered significantly...
February 20, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28258156/maternal-metabolic-stress-may-affect-oviduct-gatekeeper-function
#11
Lies Jordaens, Veerle Van Hoeck, Veronica Maillo, Alfonso Gutierrez-Adan, Waleed Fawzy A Marei, Bruno Vlaeminck, Sofie Thys, Roger G S Sturmey, Peter Bols, Jo Leroy
We hypothesized that elevated non-esterified fatty acids (NEFA) modify in vitro bovine oviduct epithelial cell (BOEC) metabolism and barrier function. Hereto, BOECs were studied in a polarized system with 24h-treatments at day 9: 1) CONTROL (0µM NEFA + 0%EtOH), 2) SOLVENT CONTROL (0µM NEFA + 0.45%EtOH), 3) BASAL NEFA (720µM NEFA + 0.45%EtOH in the basal compartment), 4) APICAL NEFA (720µM NEFA + 0.45%EtOH in the apical compartment). FITC-albumin was used for monolayer permeability assessment, and related to Transepithelial Electric Resistance (TER)...
March 3, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28254844/vegf-a-expressing-adipose-tissue-shows-rapid-beiging-enhanced-survival-after-transplantation-and-confers-il4-independent-metabolic-improvements
#12
Jiyoung Park, Min Kim, Kai Sun, Yu Aaron An, Xue Gu, Philipp E Scherer
Adipocyte-derived VEGF-A plays a crucial role in angiogenesis and contributes to adipocyte function and systemic metabolism, such as insulin resistance, chronic inflammation and beigeing of subcutaneous adipose tissue. Utilizing a doxycycline (Dox)-inducible adipocyte-specific VEGF-A overexpressing mouse model, we investigated the dynamics of local VEGF-A effects on tissue beiging of adipose tissue transplants. VEGF-A overexpression in adipocytes triggers angiogenesis. We also observe a rapid appearance of beige fat cells in subcutaneous white adipose tissue (sWATs) within as early as 2 days post induction of VEGF-A...
March 2, 2017: Diabetes
https://www.readbyqxmd.com/read/28252054/enhancement-of-porcine-intramuscular-fat-content-by-overexpression-of-the-cytosolic-form-of-phosphoenolpyruvate-carboxykinase-in-skeletal-muscle
#13
Zijian Ren, Ying Wang, Yuanyuan Ren, Zhengwei Zhang, Weiwang Gu, Zhaoting Wu, Lingyi Chen, Lisha Mou, Rongfeng Li, Haiyuan Yang, Yifan Dai
Intramuscular fat (IMF) content has been generally recognized as a desirable trait in pork meat because of its positive effect on eating quality. An effective approach to enhance IMF content in pork is the generation of transgenic pigs. In this study, we used somatic cell nuclear transfer (SCNT) to generate cloned pigs exhibiting ectopic expression of phosphoenolpyruvate carboxykinase (PEPCK-C) driven by an α-skeletal-actin gene promoter, which was specifically expressed in skeletal muscle. Using qRT-PCR and Western blot analysis, we demonstrated that PEPCK-C was functionally expressed and had a significant effect on total fatty acid content in the skeletal muscle of the transgenic pigs, while the n-6/n-3 polyunsaturated fatty acid (PUFA) ratio showed no difference between transgenic and control pigs...
March 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28246016/gut-specific-delivery-of-t-helper-17-cells-reduces-obesity-and-insulin-resistance-in-mice
#14
Chun-Pyo Hong, Areum Park, Bo-Gie Yang, Chang Ho Yun, Min-Jung Kwak, Gil-Woo Lee, Jung-Hwan Kim, Min Seong Jang, Eun-Jung Lee, Eun-Ji Jeun, Gihoon You, Kwang Soon Kim, Youngwoo Choi, Ji-Hwan Park, Daehee Hwang, Sin-Hyeog Im, Jihyun F Kim, Yoon-Keun Kim, Ju-Young Seoh, Charles D Surh, You-Me Kim, Myoung Ho Jang
BACKGROUND & AIMS: Obesity and metabolic syndrome have been associated with alterations to the intestinal microbiota. However, few studies examined the effects of obesity on the intestinal immune system. We investigated changes in subsets of intestinal CD4+ T-helper (Th) cells with obesity and the effects of gut-tropic Th17 cells in mice on a high-fat diet (HFD). METHODS: We isolated immune cells from small intestine and adipose tissue of C57BL/6 mice fed a normal chow diet or a HFD for 10 weeks and analyzed the cells by flow cytometry...
February 25, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28242932/dietary-fat-composition-food-matrix-and-relative-polarity-modulate-the-micellarization-and-intestinal-uptake-of-carotenoids-from-vegetables-and-fruits
#15
Purna Chandra Mashurabad, Ravindranadh Palika, Yvette Wilda Jyrwa, K Bhaskarachary, Raghu Pullakhandam
Dietary fat increases carotenoid bioavailability by facilitating their transfer to the aqueous micellar fraction during digestion. However, the specific effect of both quantity and type of dietary fat required for optimal carotenoid absorption remained unexplored. In the present study, the effect of amount and type of vegetable oils on carotenoid micellarization from carrot, spinach, drumstick leaves and papaya using in vitro digestion/Caco-2 cell model have been assessed. Although, dietary fat (0.5-10% w/w) significantly increased the micellarization of carotenoids from all the test foods, the extent of increase was determined by the food matrix (papaya > drumstick = spinach > carrot) and polarity of carotenoids (lutein > β-carotene = α-carotene > lycopene)...
February 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28238002/risk-factors-for-worsening-of-acute-pancreatitis-in-patients-admitted-with-mild-acute-pancreatitis
#16
Zhouxiang Jin, Lubai Xu, Xiangyu Wang, Dinghua Yang
BACKGROUND The aim of the present study was to investigate risk factors for developing more severe pancreatitis, including moderately severe (MSAP) and severe acute pancreatitis (SAP), in patients admitted with mild acute pancreatitis (MAP). MATERIAL AND METHODS Patients admitted with MAP to our hospital from March 2013 to May 2016 were included and prospectively evaluated. Possible risk factors for developing MSAP or SAP were age, blood glucose level on admission, etiology, sex, Ranson score, amylase level, Acute Physiology and Chronic Health Evaluation II (APACHE-II) scores, C-reactive protein (CRP) level, serum calcium level, visceral fat area (VFA), body mass index (BMI), whether this was the first episode of AP, and method of administration of octreotide...
February 26, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28230781/-dose-to-mother-deuterium-oxide-dilution-technique-an-accurate-strategy-to-measure-vitamin-a-intake-in-breastfed-infants
#17
Veronica Lopez-Teros, Ana Teresa Limon-Miro, Humberto Astiazaran-Garcia, Sherry A Tanumihardjo, Orlando Tortoledo-Ortiz, Mauro E Valencia
In Mexico, infants (0-2 years old) show the highest prevalence of vitamin A deficiency (VAD), measured by serum retinol concentrations. Thus, we consider that low vitamin A (VA) intake through breast milk (BM) combined with poor weaning practices are the main factors that contribute to VAD in this group. We combined the assessment of VA status in lactating women using BM retinol and a stable isotope 'dose-to-mother' technique to measure BM production in women from urban and agricultural areas. Infants' mean BM intake was 758 ± 185 mL, and no difference was observed between both areas (p = 0...
February 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28228283/adipose-type-one-innate-lymphoid-cells-regulate-macrophage-homeostasis-through-targeted-cytotoxicity
#18
Selma Boulenouar, Xavier Michelet, Danielle Duquette, David Alvarez, Andrew E Hogan, Christina Dold, Donal O'Connor, Suzanne Stutte, Ali Tavakkoli, Desmond Winters, Mark A Exley, Donal O'Shea, Michael B Brenner, Ulrich von Andrian, Lydia Lynch
Adipose tissue has a dynamic immune system that adapts to changes in diet and maintains homeostatic tissue remodeling. Adipose type 1 innate lymphoid cells (AT1-ILCs) promote pro-inflammatory macrophages in obesity, but little is known about their functions at steady state. Here we found that human and murine adipose tissue harbor heterogeneous populations of AT1-ILCs. Experiments using parabiotic mice fed a high-fat diet (HFD) showed differential trafficking of AT1-ILCs, particularly in response to short- and long-term HFD and diet restriction...
February 21, 2017: Immunity
https://www.readbyqxmd.com/read/28227390/bio-heat-transfer-model-of-electroconvulsive-therapy-effect-of-biological-properties-on-induced-temperature-variation
#19
Marilia M de Oliveira, Paul Wen, Tony Ahfock, Marilia M de Oliveira, Paul Wen, Tony Ahfock, Paul Wen, Marilia M de Oliveira, Tony Ahfock
A realistic human head model consisting of six tissue layers was modelled to investigate the behavior of temperature profile and magnitude when applying electroconvulsive therapy stimulation and different biological properties. The thermo-electrical model was constructed with the use of bio-heat transfer equation and Laplace equation. Three different electrode montages were analyzed as well as the influence of blood perfusion, metabolic heat and electric and thermal conductivity in the scalp. Also, the effect of including the fat layer was investigated...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222826/fetal-and-neonatal-exposure-to-trans-fatty-acids-impacts-on-susceptibility-to-atherosclerosis-in-apo-e-3-leiden-mice
#20
Louise Gates, Simon C Langley-Evans, Jana Kraft, Adam L Lock, Andrew M Salter
Nutrition during pregnancy can impact on the susceptibility of the offspring to CVD. Postnatal consumption of trans-fatty acids (TFA), associated with partially hydrogenated vegetable oil (PHVO), increases the risk of atherosclerosis, whereas evidence for those TFA associated with ruminant-derived dairy products and meat remain equivocal. In this study, we investigate the impact of maternal consumption of dietary PHVO (P) and ruminant milk fat (R) on the development of atherosclerosis in their offspring, using the transgenic apoE*3 Leiden mouse...
February 22, 2017: British Journal of Nutrition
keyword
keyword
7847
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"