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https://www.readbyqxmd.com/read/28081345/growing-oxa-23-type-strains-among-carbapenem-resistant-acinetobacter-baumannii-and-tigecycline-as-an-alternate-combination-therapy
#1
Şerife Altun, Zeliha Koçak Tufan, Belgin Altun, Ufuk Önde, Sami Kınıklı, Ali Pekcan Demiröz
BACKGROUND/AIM: The increasing prevalence and global spread of difficult-to-treat carbapenem-resistant Acinetobacter baumannii has become a serious problem. The aim of this study is to investigate the resistance patterns and tigecycline sensitivity of carbapenem-resistant A. baumannii strains. MATERIALS AND METHODS: Acinetobacter strains that were carbapenem-resistant and collected mainly from intensive care units were included into this study. The antibiotic sensitivity/resistance of the strains to other antibiotics and tigecycline were noted...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28030437/cerebrospinal-fluid-biomarkers-for-the-diagnosis-of-alzheimer-disease-in-south-korea
#2
Sun Ah Park, Won Seok Chae, Hyeong Jun Kim, Ho Sik Shin, Saeromi Kim, Ji Young Im, Sang Il Ahn, Kyoung Dae Min, Soo Jae Yim, Byoung Seok Ye, Sang Won Seo, Jee Hyang Jeong, Kyung Won Park, Seong Hye Choi, Duk L Na
Laboratory-specific reference values for cerebrospinal fluid (CSF) Alzheimer disease (AD) biomarkers are necessary. Our objective was to apply well-known CSF biomarkers and redetermine their diagnostic cutoff values for AD in South Korea. CSF samples from matched control subjects (n=71), patients with AD dementia (ADD, n=76), and other neurological disorders with cognitive decline (OND, n=47) were obtained from 6 Korean dementia clinics according to a standardized protocol. CSF biomarker concentrations were measured using enzyme-linked immunosorbent assay...
December 23, 2016: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/28002760/evaluating-filterability-of-different-types-of-sludge-by-statistical-analysis-the-role-of-key-organic-compounds-in-extracellular-polymeric-substances
#3
Keke Xiao, Yun Chen, Xie Jiang, Yan Zhou
An investigation was conducted for 20 different types of sludge in order to identify the key organic compounds in extracellular polymeric substances (EPS) that are important in assessing variations of sludge filterability. The different types of sludge varied in initial total solids (TS) content, organic composition and pre-treatment methods. For instance, some of the sludges were pre-treated by acid, ultrasonic, thermal, alkaline, or advanced oxidation technique. The Pearson's correlation results showed significant correlations between sludge filterability and zeta potential, pH, dissolved organic carbon, protein and polysaccharide in soluble EPS (SB EPS), loosely bound EPS (LB EPS) and tightly bound EPS (TB EPS)...
December 9, 2016: Chemosphere
https://www.readbyqxmd.com/read/27998455/-optic-nerve-subarachnoid-space-expansion-in-mr-imaging-a-etiology-study
#4
M Li, Q G Xu, J Q Wang, Y R Wang, J Zhao, S H Wei
Objective: To investigate spectrum of causes in optic nerve subarachnoid space (ONSS) expansion by using Magnetic Resonance Imaging (MRI). Methods: A retrospective study. Twenty-six patients (46 eyes) with ONSS expansion and 20 healthy adults (40 eyes) were recruited in Neuro-ophthalmology Department of Chinese PLA General Hospital from January, 2014 to December, 2015. The diameters were measured on the optic nerve (OND) and optic nerve sheath (ONSD) 2.4 mm behind the globe. ONSS was calculated by the formula of (ONSD-OND)/2...
December 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27998375/sleep-disturbances-in-oef-oif-ond-veterans-associations-with-ptsd-personality-and-coping
#5
Mackenzie J Lind, Emily Brown, Leah Farrell-Carnahan, Ruth C Brown, Sage Hawn, Erin Berenz, Scott McDonald, Treven Pickett, Carla Kmett Danielson, Suzanne Thomas, Ananda B Amstadter
STUDY OBJECTIVES: Sleep disturbances are well documented in relation to trauma exposure and posttraumatic stress disorder (PTSD), but correlates of such disturbances remain understudied in veteran populations. We conducted a preliminary study of sleep disturbances in Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn veterans (n = 133; mean [standard deviation] age = 29.8 [4.7] y). METHODS: Veterans were assigned to one of three groups based on responses to the Clinician Administered PTSD Scale: control (no trauma-exposure [TE] or PTSD), TE, and PTSD...
December 16, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27997010/-metastasi-ossee-da-carcinoma-del-colon-retto-termoablazione-con-micro-onde-per-il-trattamento-palliativo-del-dolore
#6
Daniele Maiettini, Verena De Angelis, Luigina Graziosi, Stefania Rebonato, Lorenzo Falcinelli, Giulio Metro, Alberto Rebonato
Riassunto. Il trattamento palliativo delle metastasi ossee da carcinoma del colon-retto resta controverso. Presentiamo il caso di un paziente con una metastasi del sacro sviluppata 4 anni dopo una colectomia sinistra per adenocarcinoma, trattata con una singola seduta di termoablazione con micro-onde TC-guidata. La procedura ha presentato un ottimo controllo del dolore immediatamente dopo la procedura e al follow-up a 4 mesi.
December 2016: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/27982338/rupture-of-celiac-trunk-aneurysm-in-patient-with-beh%C3%A3-et-disease
#7
Márcio Luís Lucas, Tiago Frankini, Ângelo Frankini, Newton Aerts, Tatiana Freitas Tourinho
We report a case of a ruptured aneurysm of the celiac trunk in a 32-year-old, male patient with Behçet Disease (BD). Aneurysm resection was performed and the patient is well during a follow up of 32 months. To our knowledge, this is the first reported case of a ruptured celiac trunk aneurysm successfully treated in a patient with BD. RESUMO Relatamos o caso de um aneurisma roto do tronco celíaco em um paciente de 32 anos, do sexo masculino, portador de Doença de Behçet (DB). A ressecção do aneurisma foi realizada e o paciente está bem, com acompanhamento de 32 meses...
September 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/27982332/thoracic-damage-control-surgery
#8
Roberto Gonçalves, Roberto Saad
The damage control surgery came up with the philosophy of applying essential maneuvers to control bleeding and abdominal contamination in trauma patients who are within the limits of their physiological reserves. This concept was extended to thoracic injuries, where relatively simple maneuvers can shorten operative time of in extremis patients. This article aims to revise the various damage control techniques in thoracic organs that must be known to the surgeon engaged in emergency care. RESUMO A cirurgia de controle de danos surgiu com a filosofia de se aplicar manobras essenciais para controle de sangramento e contaminação abdominal, em doentes traumatizados, nos limites de suas reservas fisiológicas...
September 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/27980130/insulinotropic-effects-of-gpr120-agonists-are-altered-in-obese-non-diabetic-and-diabetic-states
#9
Dan Zhang, Wing Yan So, Yi Wang, Shang Ying Wu, Qianni Cheng, Po Sing Leung
G protein-coupled receptor 120 (GPR120) is a putative target for obesity and diabetes therapies. However, it remains controversial whether resident GPR120 plays a direct regulatory role in islet β-cell insulin secretion. This study examined this issue in isolated rodent islets and rat β-cell line INS-1E, and assessed the role of GPR120 in islet insulin secretion in obese non-diabetic (OND) and diabetic states. GPR120 expression was detected in rodent islet β cells. Docosahexaenoic acid (DHA) and synthetic GPR120 agonist GSK137647 (GSK) augmented insulin release from rat/mouse islets and INS-1E; DHA effects were partially mediated by GPR40...
December 15, 2016: Clinical Science (1979-)
https://www.readbyqxmd.com/read/27926996/small-molecule-modulator-of-sigma-2-receptor-is-neuroprotective-and-reduces-cognitive-deficits-and-neuro-inflammation-in-experimental-models-of-alzheimer-s-disease
#10
Bitna Yi, James J Sahn, Pooneh Memar Ardestani, Andrew K Evans, Luisa Scott, Jessica Z Chan, Sangeetha Iyer, Ashley Crisp, Gabriella Zuniga, Jonathan Pierce-Shimomura, Stephen F Martin, Mehrdad Shamloo
Accumulating evidence suggests that modulating the sigma 2 receptor (Sig2R) can provide beneficial effects for neurodegenerative diseases. Herein, we report the identification of a novel class of Sig2R binding ligands and their cellular and in vivo activity in experimental models of Alzheimer's disease (AD). We report that SAS-0132 and DKR-1051, selective ligands of Sig2R, modulate intracellular Ca(2+) levels in human SK-N-SH neuroblastoma cells. The Sig2R antagonists SAS-0132 and JVW-1009 are neuroprotective in a C...
December 7, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/27862614/transorbital-sonography-and-visual-outcome-for-the-diagnosis-and-monitoring-of-optic-neuritis
#11
Piergiorgio Lochner, Maurizio A Leone, Klaus Fassbender, Roberto Cantello, Lorenzo Coppo, Raffaele Nardone, Gianni Zorzi, Martin Lesmeister, Cristoforo Comi, Francesco Brigo
BACKGROUND AND PURPOSE: Transorbital sonography (TOS) is a promising tool to support the clinical diagnosis of optic neuritis (ON) by showing thickening of optic nerve. In this study, we aimed to define its specific role in follow-up of ON patients. METHODS: We measured ultrasonography parameters and visual acuity (VA) at presentation and after 1 year in 45 patients with newly diagnosed ON. Two vascular sonographers used B-mode TOS to evaluate mean optic nerve diameter (OND) and optic nerve sheath diameter (ONSD)...
November 13, 2016: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/27860224/reduced-angiogenic-gene-expression-in-morbillivirus-triggered-oncolysis-in-a-translational-model-for-histiocytic-sarcoma
#12
Vanessa Maria Pfankuche, Ingo Spitzbarth, Stefanie Lapp, Reiner Ulrich, Ulrich Deschl, Arno Kalkuhl, Wolfgang Baumgärtner, Christina Puff
Histiocytic sarcoma represents a rare malignant tumour with a short survival time, indicating the need of novel treatment strategies including oncolytic virotherapy. The underlying molecular mechanisms of viral oncolysis are largely unknown. As cancer in companion animals shares striking similarities with human counterparts, we chose a permanent canine histiocytic sarcoma cell line (DH82 cells) to identify global transcriptome changes following infection with canine distemper virus (CDV), a paramyxovirus closely related to human measles virus...
November 17, 2016: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/27828679/innovation-in-healthcare-services-notes-on-the-limits-of-field-research
#13
Laís Silveira Costa
The contemporary context of population aging, itsthe population's different health and disease characteristics, and the growing incorporation of technologies by healthcare systems have highlighted the need to adjust the healthcare structure as a whole. The defense of a democratic and sustainable system reveals the importance of understanding how changes in healthcare take place. The current article aims to contribute to the understanding of innovation in healthcare services. The study's results indicate that the existence of certain knowledge gaps means that public policies tend to overlook a whole rangeseries of innovations normally associated with social changes, with a consequentwith an impact on human development, social cohesion, equality, and equity, allcentral issues that are central toin the field of collective public healthcare field...
November 3, 2016: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/27812638/is-there-a-rationale-for-pulmonary-rehabilitation-following-successful-chemotherapy-for-tuberculosis
#14
Marcela Muñoz-Torrico, Adrian Rendon, Rosella Centis, Lia D'Ambrosio, Zhenia Fuentes, Carlos Torres-Duque, Fernanda Mello, Margareth Dalcolmo, Rogelio Pérez-Padilla, Antonio Spanevello, Giovanni Battista Migliori
The role of tuberculosis as a public health care priority and the availability of diagnostic tools to evaluate functional status (spirometry, plethysmography, and DLCO determination), arterial blood gases, capacity to perform exercise, lesions (chest X-ray and CT), and quality of life justify the effort to consider what needs to be done when patients have completed their treatment. To our knowledge, no review has ever evaluated this topic in a comprehensive manner. Our objective was to review the available evidence on this topic and draw conclusions regarding the future role of the "post-tuberculosis treatment" phase, which will potentially affect several million cases every year...
September 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/27786515/posttraumatic-stress-and-alcohol-use-among-veterans-amygdala-and-anterior-cingulate-activation-to-emotional-cues
#15
Raluca M Simons, Jeffrey S Simons, Dawne Olson, Lee Baugh, Vincent Magnotta, Gina Forster
This fMRI study tested a model of combat trauma, posttraumatic stress symptoms (PTSS), alcohol use, and behavioral and neural responses to emotional cues in 100 OIF/OEF/OND veterans. Multilevel structural equation models were tested for left and right dorsal ACC (dACC), rostral ACC (rACC), and amygdala blood-oxygen- level dependent responses during the emotional counting Stroop test and masked faces task. In the Stroop task, combat exposure moderated the effect of combat stimuli resulting in hyperactivation in the rACC and dACC...
November 2016: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/27737375/the-impact-of-the-use-of-different-types-of-gloves-and-bare-hands-for-preparation-of-clean-surgical-instruments
#16
Camila Quartim de Moraes Bruna, Rafael Queiroz de Souza, Irineu Francisco Silva Massaia, Áurea Silveira Cruz, Kazuko Uchikawa Graziano
Objectives: to determine if there are differences on the safety of the preparation of clean surgical instruments using different types of gloves and bare hands and evaluate the microbiological load of these preparations without gloves. Method: laboratory procedure with a pragmatic approach, in which the samples were handled with different types of gloves and bare hands. In addition, cytotoxicity assays were carried out by means of the agar diffusion method. Further samples were subjected to microbiological analysis after being handled without gloves...
October 10, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27680050/impact-of-promoting-self-care-in-nursing-workload
#17
Armando Dos Santos Trettene, Cassiana Mendes Bertoncelo Fontes, Ana Paula Ribeiro Razera, Marcia Ribeiro Gomide
OBJECTIVES: To assess the impact of promoting self-care in nursing workload and associate it to the variables: age, gender, socioeconomic status, education, marital status and number of children of caregivers. METHODS: Prospective study with 31 children and their caregivers. Participants were assessed at two moments, 1st and 2nd hospitalization, the nursing workload was measured by the Nursing Activities Score (NAS). RESULTS: The mean NAS in the 1st hospitalization was 60...
July 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/27679952/profile-of-the-newly-graduated-physicians-in-southern-brazil-and-their-professional-insertion
#18
Kátia Sheylla Malta Purim, Luiza DE Martino Cruvinel Borges, Ana Carolina Possebom
Knowledge of the profile and professional integration of new graduates enables adjustments in medical education. This study evaluated 107 graduates from a private institution in the Brazilian South region, using a self-administered electronic questionnaire. There were similar participation of young physicians of both genders and higher male concentration in general surgery. Graduates are inserted in the public and private labor market. Most do extra shifts in emergency services and trauma surgery, where there is greater need for clinical and surgical skills...
July 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/27670870/cam-use-in-recently-returned-oef-oif-ond-us-veterans-demographic-and-psychosocial-predictors
#19
Crystal L Park, Lucy Finkelstein-Fox, David M Barnes, Carolyn M Mazure, Rani Hoff
OBJECTIVES: Because the use of complementary and alternative medicine (CAM) is increasing among veterans, understanding more about the characteristics of veterans who use CAM is increasingly important. Studies reporting on predictors of use almost always discuss CAM in the aggregate, yet each CAM modality represents a unique approach to healthcare, and each may have different correlates as well as different effectiveness. Very little information is available about veterans' use of each distinct modality, and about psychosocial correlates of various forms of CAM use...
October 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27664565/drinking-motives-and-ptsd-related-alcohol-expectancies-among-combat-veterans
#20
Meghan E McDevitt-Murphy, Matthew T Luciano, Jessica C Tripp, Jasmine E Eddinger
INTRODUCTION: Combat veterans are at increased risk for PTSD and alcohol misuse, and expectancies and motives for drinking may help explain the link between these comorbid issues. This investigation explored the relationships between PTSD symptoms, PTSD-related alcohol expectancies, motives for drinking, and alcohol consumption/misuse. METHOD: 67 veterans of Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn (OEF/OIF/OND) participated in this project...
January 2017: Addictive Behaviors
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