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David Gaffney, Bill Small, Henry Kitchener, Sang Young Ryu, Akila Viswanathan, Ted Trimble, Al Covens, Sarikapan Wilailak, Arb-Aroon Lertkhachonsuk, Chomporn Sitathanee, Umesh Mahantshetty, Brandon Fisher, Susan Springer, Thomas Pollatz, Antonius Spiller, Monica Bacon, Anuja Jhingran
Eighty-seven percent of cervix cancer occurs in less-developed regions of the world, and there is up to an 18-fold difference in mortality rate for cervix cancer depending on the region of the world. The Cervix Cancer Research Network (CCRN) was founded through the Gynecologic Cancer InterGroup with the aim of improving access to clinical trials in cervix cancer worldwide, and in so doing improving standards of care. The CCRN recently held its first international educational symposium in Bangkok. Sixty-two participants attended from 16 different countries including Pakistan, India, Bangladesh, Thailand, Malaysia, Singapore, Philippines, Taiwan, China, Vietnam, Korea, Japan, Columbia, Brazil, Canada, and the United States...
November 2016: International Journal of Gynecological Cancer
Jacqueline J Suijker, Marjon van Rijn, Bianca M Buurman, Gerben Ter Riet, Eric P Moll van Charante, Sophia E de Rooij
BACKGROUND: To evaluate the effects of nurse-led multifactorial care to prevent disability in community-living older people. METHODS: In a cluster randomized trail, 11 practices (n = 1,209 participants) were randomized to the intervention group, and 13 practices (n = 1,074 participants) were randomized to the control group. Participants aged ≥ 70 years were at increased risk of functional decline based on a score ≥ 2 points on the Identification of Seniors at Risk- Primary Care, ISAR-PC...
2016: PloS One
Bianca M Buurman, Juliette L Parlevliet, Heather G Allore, Willem Blok, Bob A J van Deelen, Eric P Moll van Charante, Rob J de Haan, Sophia E de Rooij
IMPORTANCE: Older adults acutely hospitalized are at risk of disability. Trials on comprehensive geriatric assessment (CGA) and transitional care present inconsistent results. OBJECTIVE: To test whether an intervention of systematic CGA, followed by the transitional care bridge program, improved activities of daily living (ADLs) compared with systematic CGA alone. DESIGN, SETTING, AND PARTICIPANTS: This study was a double-blind, multicenter, randomized clinical trial conducted at 3 hospitals with affiliated home care organizations in the Netherlands between September 1, 2010, and March 1, 2014...
March 2016: JAMA Internal Medicine
Christine Boev, Ying Xue, Gail L Ingersoll
OBJECTIVE: The purpose of this study was to examine the relationship between nursing job satisfaction and healthcare-associated infections (HAIs) in adult critical care. METHODS: Multilevel modelling was used to examine the relationship between nursing job satisfaction and two HAIs, ventilator-associated pneumonia (VAP) and central-line associated bloodstream infections (CLABSI). RESULTS: Units with nurses that reported satisfaction with organisational policies were associated with a 6...
October 2015: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
Hong Li, Yuan Zhou, Ziding Zhang
By analyzing protein-protein interaction (PPI) networks, one can find that a protein may have multiple binding partners. However, it is difficult to determine whether the interactions with these partners occur simultaneously from binary PPIs alone. Here, we construct the yeast and human competition-cooperation relationship networks (CCRNs) based on protein structural interactomes to clearly exhibit the relationship (competition or cooperation) between two partners of the same protein. If two partners compete for the same interaction interface, they would be connected by a competitive edge; otherwise, they would be connected by a cooperative edge...
2015: Scientific Reports
Gita Suneja, Monica Bacon, William Small, Sang Y Ryu, Henry C Kitchener, David K Gaffney
INTRODUCTION: The burden of cervical cancer is large and growing in developing countries, due in large part to limited access to screening services and lack of human papillomavirus (HPV) vaccination. In spite of modern advances in diagnostic and therapeutic modalities, outcomes from cervical cancer have not markedly improved in recent years. Novel clinical trials are urgently needed to improve outcomes from cervical cancer worldwide. METHODS: The Cervix Cancer Research Network (CCRN), a subsidiary of the Gynecologic Cancer InterGroup, is a multi-national, multi-institutional consortium of physicians and scientists focused on improving cervical cancer outcomes worldwide by making cancer clinical trials available in low-, middle-, and high-income countries...
2015: Frontiers in Oncology
Baris A Ozdemir, Alan Karthikesalingam, Sidhartha Sinha, Jan D Poloniecki, Robert J Hinchliffe, Matt M Thompson, Jonathan D Gower, Annette Boaz, Peter J E Holt
INTRODUCTION: The aims of this study were to describe the key features of acute NHS Trusts with different levels of research activity and to investigate associations between research activity and clinical outcomes. METHODS: National Institute for Health Research (NIHR) Comprehensive Clinical Research Network (CCRN) funding and number of patients recruited to NIHR Clinical Research Network (CRN) portfolio studies for each NHS Trusts were used as markers of research activity...
2015: PloS One
Connie Paine
Connie Paine, RN, CCRN, is a staff nurse in the intensive care unit at UCSD/Thornton Hospital in La Jolla, California.
August 2014: Critical Care Nurse
Jessica R B Musselman, Logan G Spector, Mark D Krailo, Gregory H Reaman, Amy M Linabery, Jenny N Poynter, Susan K Stork, Peter C Adamson, Julie A Ross
BACKGROUND: The Childhood Cancer Research Network (CCRN) was established within the Children's Oncology Group (COG) in July 2008 to provide a centralized pediatric cancer research registry for investigators conducting approved etiologic and survivorship studies. The authors conducted an ecological analysis to characterize CCRN catchment at >200 COG institutions by demographic characteristics, diagnosis, and geographic location to determine whether the CCRN can serve as a population-based registry for childhood cancer...
October 1, 2014: Cancer
Claire Curran
Recent advances in smartphone technology now allow clinicians to use commercially produced applications when studying for nursing certification examinations. The quality of currently available CCRN review applications varies in this first generation of products. Most are limited to multiple-choice practice questions, although a few have additional elements such as study guides and reference charts. Weaknesses found in the applications evaluated include poorly written and edited content, questions limited to rote memorization rather than application and analysis of knowledge, and content too basic or outside the scope of experienced critical care nursing practice...
June 2014: Critical Care Nurse
Ngozi Moneke, Wynklett Parsons, Mary Moran, Annette Davidek
No abstract text is available yet for this article.
April 2014: Critical Care Nurse
William J Sieber, Benjamin F Miller, Rodger S Kessler, Jo Ellen Patterson, Gene A Kallenberg, Todd M Edwards, Zephon D Lister
Collaborative care has increased dramatically in the past decade, yet the variability in collaborative strategies and the diversity of settings in which collaboration is being implemented make it difficult to assess quality and outcomes. Therefore, three aims were addressed in the current study: (a) describe and characterize the sites in the Collaborative Care Research Network (CCRN), (b) identify factors associated with practices' self-identified collaborative care model (e.g., coordinated, integrated, care management), and (c) identify limitations of available survey data elements so as to propose additional elements for future surveys...
September 2012: Families, Systems & Health: the Journal of Collaborative Family Healthcare
Theresa M Davis, Connie Barden, Carol Olff, Mary Pat Aust, Maureen A Seckel, Crystal L Jenkins, Wendy Deibert, Phyllis Griffin, Pat Herr, Carrie Hawkins, Mary McCarthy
The American Association of Critical-Care Nurses (AACN) is the world's largest specialty nursing organization. The AACN Certification Corporation provides credentialing to validate nursing practice in acute and critical care. The advent of tele-ICU nursing added a challenge to the application of certification in a new specialty area. Nurses working in a tele-ICU have many years of experience in hands-on acute or critical care nursing at the bedside. In their role as tele-ICU nurses, these skills are applied to the assessment, evaluation, and decision support of care for critically ill patients in various acute and critical care units from remote locations connected directly to the ICU through high-speed audio and video technology...
October 2012: Critical Care Nursing Quarterly
Carrie L Hawkins
The first of its kind in the Veterans Affairs (VA) system, the Denver VA Medical Center's tele-intensive care unit (ICU) program is unique because it is entirely nurse driven. A nontraditional tele-ICU model, the program was tailored to meet the needs of rural veterans by using critical care nursing expertise in Denver, Colorado. An experienced CCRN-certified nurse manages the system 24 hours a day, 7 days a week, from Eastern Colorado Health Care System. The virtual ICU provides rapid response interventions through virtual technology...
July 2012: AACN Advanced Critical Care
Serena Phromsivarak Kelly, Ccrn Robert Steelman, Mary Frances D Pate
No abstract text is available yet for this article.
July 2011: AACN Advanced Critical Care
Michael J Reilly, David Markenson
INTRODUCTION: While many hospitals have developed preliminary emergency department and in-patient surge plans, the ability to surge is often limited by critical resources. The resource which is often the most limited is usually the human resource and within this category the limiting factor is almost universally nursing. As a result, nursing shortages can result in an inability of a hospital or emergency department to create surge capacity to deal with large numbers of ill or injured patients...
May 2010: American Journal of Disaster Medicine
Kim S Thomas
BACKGROUND: Cellulitis is a very common condition that often recurs. The PATCH II study was designed to explore the possibility of preventing future episodes of cellulitis, with resultant cost savings for the NHS. This was the first trial to be undertaken by the UK Dermatology Clinical Trials Network. As such, it was the first to test a recruitment model that involved many busy clinicians each contributing just a few patients. METHODS: A double-blind randomised controlled trial comparing prophylactic antibiotics (penicillin V) with placebo tablets, for the prevention of repeat episodes of cellulitis of the leg...
March 2, 2010: Trials
A Silman
In October 2007, the UK Arthritis Research Campaign (ARC) launched a new approach for the support of clinical trials and related research in the UK. The initiative depends on a partnership between ARC, the UK Clinical Research Network (UKCRN) and the pharmaceutical and related industry. The aim is to develop nationally agreed strategic plans for intervention research for the major musculoskeletal disorders. These will range from testing experimental therapies to novel approaches/ways of using existing interventions, taking advantage of the opportunities afforded for the enhanced support for clinical trials promised by the establishment of local research networks within the National Institute for Health Research (NIHR) Comprehensive Clinical Research Network (CCRN)...
June 2008: Rheumatology
Terrance P McGuire
The Catholic Collaborative Refugee Network (CCRN) was established more than four years ago as a result of discussions among CHA, Catholic Charities USA, and the U.S. Conference of Catholic Bishops' office of Migration and Refugee Services. The dozen CCRN sites each provide an organized response to the social, economic, and health problems often faced by refugees. Although the sites differ in their services, they typically help refugees prepare for and find work, preferably work with health insurance coverage...
January 2005: Health Progress
Assen Jablensky
OBJECTIVE: To provide an overview of the development, approaches and main research projects of the Centre for Clinical Research in Neuropsychiatry (CCRN) in Perth, Western Australia. METHOD: Discursive. RESULTS: Underlying concepts, methods and selected findings of recent research into the neurobiology and epidemiology of schizophrenia, autism and other psychotic disorders are presented. CONCLUSION: CCRN, one of Australia's youngest centres of psychiatric research, has invested fruitfully in research areas such as molecular genetics, neuropsychology, neurophysiology, behavioural pharmacology, diagnostic assessment procedures and record linkage epidemiology...
May 2004: Australian and New Zealand Journal of Psychiatry
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