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Binge Eating Disorder and biomarkers

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https://www.readbyqxmd.com/read/27804899/disrupted-resting-state-brain-network-properties-in-obesity-decreased-global-and-putaminal-cortico-striatal-network-efficiency
#1
K Baek, L S Morris, P Kundu, V Voon
BACKGROUND: The efficient organization and communication of brain networks underlie cognitive processing and their disruption can lead to pathological behaviours. Few studies have focused on whole-brain networks in obesity and binge eating disorder (BED). Here we used multi-echo resting-state functional magnetic resonance imaging (rsfMRI) along with a data-driven graph theory approach to assess brain network characteristics in obesity and BED. METHOD: Multi-echo rsfMRI scans were collected from 40 obese subjects (including 20 BED patients) and 40 healthy controls and denoised using multi-echo independent component analysis (ME-ICA)...
November 2, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27370231/randomized-controlled-trial-of-a-12-month-computerized-mindfulness-based-intervention-for-obese-patients-with-binge-eating-disorder-the-mindob-study-protocol
#2
Alexis Ruffault, Claire Carette, Kàtia Lurbe I Puerto, Nicolas Juge, Alain Beauchet, Jean-Jacques Benoliel, Jean-Marc Lacorte, Jean F Fournier, Sébastien Czernichow, Cécile Flahault
BACKGROUND: Mindfulness-based interventions for healthy behaviors such as exercise and dietary modifications have aroused growing interest. This study aims to test the effectiveness of a mindfulness-based intervention for the reduction of impulsive eating and the improvement of motivation to exercise among obese individuals. METHODS: One-hundred and twenty obese outpatients, aged 18 to 65years, diagnosed with a binge eating disorder, will be randomly assigned to one of the three following groups: mindfulness practice, sham meditation, or treatment as usual control...
July 2016: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/27254754/dopamine-pathway-imbalance-in-mice-lacking-magel2-a-prader-willi-syndrome-candidate-gene
#3
Chloe Luck, Martha H Vitaterna, Rachel Wevrick
The etiology of abnormal eating behaviors, including binge-eating disorder, is poorly understood. The neural circuits modulating the activities of the neurotransmitters dopamine and serotonin are proposed to be dysfunctional in individuals suffering from eating disorders. Prader-Willi syndrome is a neurodevelopmental disorder that causes extreme food seeking and binge-eating behaviors together with reduced satiety. One of the genes implicated in Prader-Willi syndrome, Magel2, is highly expressed in the regions of the brain that control appetite...
August 2016: Behavioral Neuroscience
https://www.readbyqxmd.com/read/25443762/weight-cycling-in-bipolar-disorder
#4
Eva Z Reininghaus, Nina Lackner, Frederike T Fellendorf, Susanne Bengesser, Armin Birner, Bernd Reininghaus, Renate Unterweger, Martina Platzer, Sandra J Wallner-Liebmann, Sieglinde Zelzer, Harald Mangge, Dietmar Fuchs, Hans-Peter Kapfhammer, Roger S McIntyre
BACKGROUND: An association between excess weight and/or weight fluctuations and cardiovascular morbidity and mortality is amply documented. Individuals with bipolar disorder (BD) are differentially affected by overweight/obesity, chaotic eating patterns (e.g., binge eating), as well as cardiovascular morbidity and mortality. Weight cycling (WCYC) is defined as a pattern of repetitive weight loss and gain. METHODS: We sought to determine the relationship between course of illness and BD and WCYC retrospectively as well whether these co-occurring phenotypes identify a biologically distinct subpopulation on the basis of having a unique inflammatory biomarker/biosignature profile...
January 15, 2015: Journal of Affective Disorders
https://www.readbyqxmd.com/read/25149200/urinary-cortisol-and-psychopathology-in-obese-binge-eating-subjects
#5
Luca Lavagnino, Federico Amianto, Mirko Parasiliti Caprino, Mauro Maccario, Emanuela Arvat, Ezio Ghigo, Giovanni Abbate Daga, Secondo Fassino
BACKGROUND: Investigations on the relationship between obesity, binge eating and the function of hypothalamic-pituitary-adrenal (HPA) axis have led to inconsistent results. General psychopathology affects HPA axis function. The present study aims to examine correlations between binge eating, general psychopathology and HPA axis function in obese binge eaters. METHODS: Twenty-four hour urinary free cortisol (UFC/24 h) was measured in 71 obese binge eating women...
December 2014: Appetite
https://www.readbyqxmd.com/read/17628126/management-of-eating-disorders
#6
REVIEW
Nancy D Berkman, Cynthia M Bulik, Kimberly A Brownley, Kathleen N Lohr, Jan A Sedway, Adrienne Rooks, Gerald Gartlehner
OBJECTIVES: The RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center (RTI-UNC EPC) systematically reviewed evidence on efficacy of treatment for anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED), harms associated with treatments, factors associated with the treatment efficacy and with outcomes of these conditions, and whether treatment and outcomes for these conditions differ by sociodemographic characteristics. DATA SOURCES: We searched MEDLINE, the Cumulative Index to Nursing and Applied Health (CINAHL), PSYCHINFO, the Educational Resources Information Center (ERIC), the National Agricultural Library (AGRICOLA), and Cochrane Collaboration libraries...
April 2006: Evidence Report/technology Assessment
https://www.readbyqxmd.com/read/17370291/outcomes-of-eating-disorders-a-systematic-review-of-the-literature
#7
REVIEW
Nancy D Berkman, Kathleen N Lohr, Cynthia M Bulik
OBJECTIVE: The RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center systematically reviewed evidence on factors associated with outcomes among individuals with anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED) and whether outcomes differed by sociodemographic characteristics. METHOD: We searched electronic databases including MEDLINE and reviewed studies published from 1980 to September, 2005, in all languages against a priori inclusion/exclusion criteria and focused on eating, psychiatric or psychological, or biomarker outcomes...
May 2007: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/17370289/binge-eating-disorder-treatment-a-systematic-review-of-randomized-controlled-trials
#8
REVIEW
Kimberly A Brownley, Nancy D Berkman, Jan A Sedway, Kathleen N Lohr, Cynthia M Bulik
OBJECTIVE: The Research Triangle Institute-University of North Carolina Evidence Based Practice Center (RTI-EPC) systematically reviewed evidence on efficacy of treatment for binge eating disorder (BED), harms associated with treatments, factors associated with treatment efficacy, and differential outcome by sociodemographic characteristics. METHOD: We searched six major databases for studies on the treatment of BED published from 1980 to September, 2005, in all languages against a priori inclusion/exclusion criteria and focused on eating, psychiatric or psychological, or biomarker outcomes...
May 2007: International Journal of Eating Disorders
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