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Keywords Binge Eating Disorder and trea...

Binge Eating Disorder and treatment

https://read.qxmd.com/read/38398053/influence-of-nucb-nesfatin-1-polymorphism-on-treatment-response-to-naltrexone-bupropion-sr-in-binge-eating-disorder-and-obesity
#21
JOURNAL ARTICLE
Elvira Anna Carbone, Mariarita Caroleo, Marianna Rania, Renato de Filippis, Francesca Condoleo, Federica Catalano, Matteo Aloi, Pasquale De Fazio, Franco Arturi, Marta Letizia Hribal, Teresa Vanessa Fiorentino, Cristina Segura-Garcia
Background and Objectives : The NUCB2 gene and its polymorphisms were identified as novel players in the regulation of food intake, potentially leading to obesity (OBE) and altered eating behaviors. Naltrexone/bupropion SR (NB) showed good efficacy and tolerability for treating OBE and altered eating behaviors associated with binge eating disorder (BED). This prospective study investigates the influence of NUCB2 gene polymorphism on NB treatment response in OBE and BED. Materials and Methods : Body mass index (BMI), eating (EDE-Q, BES, NEQ, GQ, Y-FAS 2...
February 17, 2024: Biomedicines
https://read.qxmd.com/read/38391755/impulse-control-disorders-in-parkinson-s-disease-and-atypical-parkinsonian-syndromes-is-there-a-difference
#22
JOURNAL ARTICLE
Mateusz Toś, Anna Grażyńska, Sofija Antoniuk, Joanna Siuda
BACKGROUND AND OBJECTIVES: Impulse control disorders (ICDs) are characterized by potentially harmful actions resulting from disturbances in the self-control of emotions and behavior. ICDs include disorders such as gambling, hypersexuality, binge eating, and compulsive buying. ICDs are known non-motor symptoms in Parkinson's disease (PD) and are associated primarily with the use of dopaminergic treatment (DRT) and especially dopamine agonists (DA). However, in atypical parkinsonism (APS), such as progressive supranuclear palsy (PSP) or multiple system atrophy (MSA), there are only single case reports of ICDs without attempts to determine the risk factors for their occurrence...
February 16, 2024: Brain Sciences
https://read.qxmd.com/read/38390214/psychiatric-adverse-events-associated-with-glp-1-receptor-agonists-a-real-world-pharmacovigilance-study-based-on-the-fda-adverse-event-reporting-system-database
#23
JOURNAL ARTICLE
Wei Chen, Peishan Cai, Wenbin Zou, Zhiwen Fu
BACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are widely used due to their profound efficacy in glycemic control and weight management. Within real-world contexts, the manifestation of certain psychiatric adverse events (AEs) has been observed, which is potentially linked to the administration of GLP-1 RAs. The objective of this study was to undertake a comprehensive investigation and characterization of the psychiatric AEs associated with GLP-1 RAs. METHODS: We retrieved reports of AEs associated with treatment with GLP-1 RAs during the period from the first quarter (Q1) of 2004 to Q1 2023 from the FDA Adverse Event Reporting System (FAERS) database...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38383957/is-there-a-basis-for-a-weight-cut-off-point-a-large-scale-investigation-of-atypical-anorexia-and-anorexia-nervosa-subtypes-among-patients-at-a-residential-treatment-centre
#24
JOURNAL ARTICLE
Valerie Z Wong, Michael R Lowe
OBJECTIVE: There is debate surrounding how to differentiate between anorexia nervosa (AN) and atypical AN (atypAN) as diagnostic entities, and whether a distinction based on BMI is warranted. Better understanding eating disorder (ED) and emotional symptoms across atypAN and AN subtypes [AN-restricting (AN-R), AN-binge/purge (AN-BP)], with and without controlling for BMI, can elucidate how atypAN differs from AN subtypes and whether there is a basis for a BMI cut-off. METHODS: 1810 female patients at an ED treatment centre completed intake surveys...
February 21, 2024: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://read.qxmd.com/read/38380659/-eating-disorders-in-the-light-of-addiction
#25
JOURNAL ARTICLE
Hélène Tzieropoulos Osterlof, Guillaume Wegmüller, Sophie Vust, Françoise Lier, Marco Savoia, Cindy Soroken
Eating disorders (ED) are complex and damaging to health. They cause suffering similar to that of addictions. Although they share some similarities, eating disorders remain distinct from addictions. Fundamental differences emerge in binge eating and restrictive behaviors. Eating disorder treatment in adolescents relies mainly on family therapy and can incorporate a reflection on these similarities and differences. For instance, understanding the addictive nature of the illness helps parents and patients to avoid sterile negotiations around food...
February 21, 2024: Revue Médicale Suisse
https://read.qxmd.com/read/38371436/managing-binge-eating-disorder-in-a-young-adolescent-female-barriers-to-treatment-and-recommendations
#26
Rajesh K Mehta, Rahul Tyagi
Binge eating disorder (BED) is a behavioral disorder characterized by chronic and compulsive overeating. It is the most prevalent eating disorder in the USA, affecting almost 3% of the US population. In this study, we describe a case of BED in an adolescent Caucasian female who could not obtain specialized treatment because of financial constraints and saw a child and adolescent psychiatrist for medication management. Her treatment plan combined bupropion with family therapy and resulted in successful alleviation of her symptoms, allowing her to achieve a better quality of life...
February 2024: Curēus
https://read.qxmd.com/read/38363468/treatment-of-binge-eating-disorder-across-the-lifespan-an-updated-review-of-the-literature-and-considerations-for-future-research
#27
REVIEW
Kathryn E Smith, Andrea B Goldschmidt
PURPOSE OF REVIEW: The present review describes the recent literature on treatment for binge-eating disorder (BED) in adults and youth, with a particular focus on research gaps, emerging treatments, and future research directions. RECENT FINDINGS: Evidence supports the efficacy of several treatment modalities in adults, including self-help treatment, clinician-led psychotherapy, and pharmacotherapy; the largest effect sizes have been found for psychotherapies, most of which were cognitive-behavioral in orientation...
February 16, 2024: Current Obesity Reports
https://read.qxmd.com/read/38358009/expectations-of-a-new-eating-disorder-treatment-and-its-delivery-perspectives-of-patients-and-new-therapists
#28
JOURNAL ARTICLE
Therese Fostervold Mathisen, Gunn Pettersen, Jan H Rosenvinge, Ulrike H Schmidt, Jorunn Sundgot-Borgen
BACKGROUND: A significant number of people with bulimia nervosa (BN) or binge-eating disorder (BED) do not seek professional help. Important reasons include limited knowledge of eating disorders (EDs), feelings of shame, treatment costs, and restricted access to specialized healthcare. In this study, we explored if a novel therapy delivered in a primary care setting could overcome these barriers. We investigated factors such as motivation and expectations and included the patients' and newly trained therapists' perspectives...
February 15, 2024: International Journal of Eating Disorders
https://read.qxmd.com/read/38355050/visceral-sensitivity-hunger-responsiveness-and-satiety-responsiveness-associations-between-facets-of-gastrointestinal-interoception-and-disordered-eating-profiles-in-an-undergraduate-sample
#29
JOURNAL ARTICLE
Kendall Poovey, Diana Rancourt
This preregistered study examined associations between empirically derived profiles of disordered eating in a diverse nonclinical sample and three facets of gastrointestinal (GI) interoception (visceral sensitivity, hunger responsiveness, satiety responsiveness). University students (n = 591; 53.3% women; 23.0% Hispanic) completed the Visceral Sensitivity Index, Adult Eating Behavior Questionnaire, and Eating Pathology Symptom Inventory. Latent profile analysis was conducted in Mplus v8.3 with four behavioral indicators (restricting, binge eating, excessive exercise, purging [binary])...
February 13, 2024: Appetite
https://read.qxmd.com/read/38352466/adaptations-of-an-online-cognitive-behavioral-therapy-intervention-for-binge-purge-type-eating-disorders-in-publicly-insured-and-uninsured-adults-a-pilot-study
#30
Siena S Vendlinski, Agatha A Laboe, Peyton Crest, Claire G McGinnis, Molly Fennig, Denise E Wilfley, C Barr Taylor, Ellen E Fitzsimmons-Craft, Erin C Accurso
Background Publicly-insured and uninsured individuals-many of whom are marginalized because of race/ethnicity, disability and/or sexual preferences-experience barriers to accessing evidence-based interventions for eating disorders (EDs). Additionally, EBIs have not been developed with or for diverse populations, exacerbating poor treatment uptake. Mobile technology is perfectly positioned to bridge this gap and increase access to low-cost, culturally-sensitive EBIs. Methods This study leverages a user-centered design approach to adapt an existing coached cognitive-behavioral therapy-based digital program and evaluate its usability in a sample of 11 participants with (sub)clinical binge-purge type EDs who are publicly-insured ( n  = 10) or uninsured ( n  = 1)...
February 2, 2024: Research Square
https://read.qxmd.com/read/38345771/systematic-review-of-mindfulness-based-interventions-for-weight-management-among-pre-and-post-bariatric-surgery-patients
#31
JOURNAL ARTICLE
Yara Almuhtadi, Samah Alageel
CONTEXT: Bariatric surgery has been an effective treatment for severe obesity. However, it can be challenging for bariatric-surgery patients to reach and maintain long-term weight loss. Behavioral interventions may be beneficial in reducing weight and improving the psychological outcomes of bariatric patients. OBJECTIVE: The review intended to evaluate the benefits of mindfulness training for weight management among pre- and postoperative, bariatric-surgery patients and to help determine the design of the most effective mindfulness program for them...
July 2023: Advances in Mind-body Medicine
https://read.qxmd.com/read/38344858/therapeutic-alliance-in-two-forms-of-guided-self-help-for-binge-eating
#32
JOURNAL ARTICLE
Paul E Jenkins, Shannon Wake
The role of therapeutic alliance within psychological treatments for eating disorders (EDs), including those delivered remotely, is well established. However, few studies have investigated alliance in guided self-help, a widely recommended first-line treatment for EDs characterised by regular binge eating. Using data from a randomised controlled trial, the current study examined both facilitator and patient assessments of alliance within e-mail-assisted and face-to-face guided self-help and looked at associations between alliance, ED symptoms and ED-related impairment...
2024: Clinical Psychology & Psychotherapy
https://read.qxmd.com/read/38335315/does-hopelessness-predict-treatment-outcomes-in-adults-with-binge-spectrum-eating-disorders
#33
JOURNAL ARTICLE
Ross M Sonnenblick, Megan L Wilkinson, Stephanie M Manasse, Adrienne S Juarascio
Using data from 165 adult participants who enrolled in four studies of cognitive-behavioral therapy (CBT) for binge-spectrum eating disorders (EDs), this secondary analysis examined 1) whether pretreatment hopelessness predicted posttreatment eating pathology, loss-of-control (LOC) eating frequency, and purging frequency; 2) whether treatment had an indirect effect on those outcomes through change in hopelessness; and 3) whether treatment had an indirect effect on hopelessness through those ED measures. The Eating Disorder Examination was used to assess overall eating pathology, LOC frequency, and purging frequency...
February 9, 2024: Eating Disorders
https://read.qxmd.com/read/38331429/discovery-of-nivasorexant-act-539313-the-first-selective-orexin-1-receptor-antagonist-so1ra-investigated-in-clinical-trials
#34
JOURNAL ARTICLE
Jodi T Williams, Martin H Bolli, Christine Brotschi, Thierry Sifferlen, Michel A Steiner, Alexander Treiber, John Gatfield, Christoph Boss
The orexin system consists of two neuropeptides (orexins A and B) and two receptors (OX1 and OX2). Selective OX1 receptor antagonists (SO1RA) are gaining interest for their potential use in the treatment of CNS disorders, including substance abuse, eating, obsessive compulsive, or anxiety disorders. While blocking OX2 reduces wakefulness, the expected advantage of selectively antagonizing OX1 is the ability to achieve clinical efficacy without the promotion of sleep. Herein we report our discovery efforts starting from a dual orexin receptor antagonist and describe a serendipitous finding that triggered a medicinal chemistry program that culminated in the identification of the potent SO1RA ACT-539313...
February 8, 2024: Journal of Medicinal Chemistry
https://read.qxmd.com/read/38324959/associations-between-posttraumatic-stress-disorder-and-eating-disorder-symptoms-among-women-veterans
#35
JOURNAL ARTICLE
Sarah E Siegel, Rachel M Ranney, Robin M Masheb, Joy Huggins, Shira Maguen
Recent research suggests high rates of posttraumatic stress disorder (PTSD) and eating disorder (ED) comorbidity in women veterans. This study aims to expand the literature by examining associations between PTSD and ED diagnoses and symptoms in this population. We assessed probable PTSD diagnosis and symptom clusters (intrusion, avoidance, arousal and reactivity, and negative alterations in cognition and mood [NACM]), as well as probable Binge Eating Disorder (BED) diagnosis and ED subscales (dietary restraint, shape/weight overvaluation, and body dissatisfaction) in a sample of women veterans (N = 371)...
January 2024: Eating Behaviors
https://read.qxmd.com/read/38321617/overvaluation-of-shape-weight-at-posttreatment-predicts-relapse-at-12-month-follow-up-after-successful-behaviorally-based-treatment-of-binge-eating-disorder
#36
JOURNAL ARTICLE
Carlos M Grilo, Valentina Ivezaj, Ralitza Gueorguieva
OBJECTIVE: To test whether overvaluation of shape/weight at the end of treatment prospectively predicts relapse at 12-month follow-up in patients with binge-eating disorder (BED). METHOD: Participants were 129 patients with BED who achieved abstinence from binge eating after 6 months of behaviorally-based weight-loss treatments in a clinical trial. Independent assessments conducted at posttreatment and at 12-month follow-up included the Eating Disorder Examination interview, the Beck Depression Inventory, and weight measurements...
February 6, 2024: International Journal of Eating Disorders
https://read.qxmd.com/read/38311600/reliability-of-the-original-and-brief-versions-of-the-eating-disorder-examination-in-binge-eating-disorder
#37
JOURNAL ARTICLE
Janet A Lydecker, Valentina Ivezaj, Ashley A Wiedemann, Stephanie Kerrigan, Carlos M Grilo
OBJECTIVE: Psychometric studies evaluating the reliability of eating-disorder assessment among individuals with binge-eating disorder (BED) have been limited. The current study documents the interrater reliability and internal consistency of the Eating Disorder Examination (EDE) interview when administered to adults with Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) (DSM-5)-defined BED. METHODS: Participants (N = 56) were adults seeking treatment for BED in the context of clinical trials testing pharmacological and psychological treatments...
February 4, 2024: Obesity
https://read.qxmd.com/read/38308384/the-children-of-parents-who-receive-treatment-for-binge-eating-disorder-experience-improvements-in-disordered-eating
#38
JOURNAL ARTICLE
Janet A Lydecker, Elise V Ozbardakci, Carlos M Grilo
OBJECTIVE: Parental eating disorders are associated with disordered eating behaviors and psychopathology in their children, but it is not known whether parent treatment for binge-eating disorder (BED) is associated with changes in child disordered eating behaviors and weight. Benefits or the "ripple" effect of treatment on untreated family members has been described in the obesity literature but not for BED. METHOD: Participants evaluated for two randomized clinical trials for BED were screened for whether they had children...
February 2, 2024: International Journal of Eating Disorders
https://read.qxmd.com/read/38298797/functional-connectivity-mechanisms-underlying-symptom-reduction-following-lisdexamfetamine-treatment-in-binge-eating-disorder-a-clinical-trial
#39
JOURNAL ARTICLE
Kristi R Griffiths, Isabella A Breukelaar, Grace Harvie, Jenny Yang, Sheryl L Foster, Anthony W Harris, Simon Clarke, Phillipa J Hay, Stephen Touyz, Mayuresh S Korgaonkar, Michael R Kohn
BACKGROUND: Speculation exists as to whether lisdexamfetamine dimesylate (LDX) acts on the functional connectivity (FC) of brain networks that modulate appetite, reward, or inhibitory control in binge-eating disorder (BED). Better insights into its action may help guide the development of more targeted therapeutics and identify who will benefit most from this medication. Here, we use a comprehensive data-driven approach to investigate the brain FC changes that underlie the therapeutic action of LDX in patients with BED...
January 2024: Biol Psychiatry Glob Open Sci
https://read.qxmd.com/read/38297469/probiotic-and-prebiotic-interventions-in-eating-disorders-a%C3%A2-narrative-review
#40
REVIEW
Isabel Baenas, Lucía Camacho-Barcia, Romina Miranda-Olivos, Neus Solé-Morata, Alejandra Misiolek, Susana Jiménez-Murcia, Fernando Fernández-Aranda
AIMS: The review aimed to summarise and discuss findings focused on therapeutic probiotic and prebiotic interventions in eating disorders (ED). METHODS: Using PubMed/MEDLINE, Cochrane Library, and Web of Science all published studies were retrieved until February 2023, following PRISMA guidelines. From the 111 initial studies, 5 met the inclusion criteria for this review. RESULTS: All studies included in this narrative review were focused on anorexia nervosa (AN)...
January 31, 2024: European Eating Disorders Review: the Journal of the Eating Disorders Association
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