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Binge Eating Disorder and treatment

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https://www.readbyqxmd.com/read/29149654/classifying-binge-eating-disordered-adolescents-based-on-severity-levels
#1
Antonios Dakanalis, Maria Assunta Zanetti, Fabrizia Colmegna, Giuseppe Riva, Massimo Clerici
The new severity criterion for binge-eating disorder (BED), introduced by the most recent (fifth) edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) as a means of addressing within-group variability in severity, was tested in 223 Italian (13-18-year-old) adolescents (86.1% females) with (DSM-5) BED presenting for treatment. Analyses revealed that participants classified with mild (35.9% of the sample), moderate (38.1%) severe (13.4%), and extreme (12.6%) severity of BED, based on their clinician-rated weekly frequency of binge-eating (BE) episodes, were statistically distinguishable in physical characteristics (body mass index) and a range of clinical variables regarding eating-related psychopathology and putative maintenance factors, health-related quality of life, and mood and anxiety disorder comorbidity (medium-to-large effect sizes)...
November 14, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/29144185/rest-activity-circadian-rhythm-and-sleep-quality-in-patients-with-binge-eating-disorder
#2
E Roveda, A Montaruli, L Galasso, C Pesenti, E Bruno, P Pasanisi, M Cortellini, S Rampichini, S Erzegovesi, A Caumo, F Esposito
Recent findings suggest that altered rest-activity circadian rhythms (RARs) are associated with a compromised health status. RARs abnormalities have been observed also in several pathological conditions, such as cardiovascular, neurological, and cancer diseases. Binge eating disorder (BED) is the most common eating disorder, with a prevalence of 3.5% in women and 2% in men. BED and its associate obesity and motor inactivity could induce RARs disruption and have negative consequences on health-related quality of life...
November 16, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29134566/lisdexamfetamine-a-review-in-binge-eating-disorder
#3
Young-A Heo, Sean T Duggan
Oral lisdexamfetamine dimesylate (Vyvanse(®); lisdexamfetamine), a prodrug of dextroamfetamine, is currently the only drug to be approved in the USA for the treatment of moderate to severe binge eating disorder (BED) in adult patients. Its approval was based on the results of two pivotal short-term (12 weeks) phase III studies, which showed a significantly greater reduction in binge eating days/week at the end of the study with lisdexamfetamine 50-70 mg/day than with placebo. The findings of these studies have been supported and extended by the results of longer-term (≤ 52 weeks) phase III studies, including one with a randomized 26-week withdrawal phase, which showed that lisdexamfetamine markedly reduced the risk of BED relapse relative to placebo...
November 13, 2017: CNS Drugs
https://www.readbyqxmd.com/read/29128522/biological-evidence-for-attention-bias-to-food-emotional-dysregulation-disinhibition-and-deficient-somatosensory-awareness-in-obesity-with-binge-eating-disorder
#4
Roni Aviram-Friedman, Nerys Astbury, Christopher N Ochner, Isobel Contento, Allan Geliebter
OBJECTIVES: To refine the biobehavioral markers of binge eating disorder (BED). METHODS: We conducted fMRI brain scans using images of high energy processed food (HEPF), low energy unprocessed food (LEUF), or non-foods (NF) in 42 adults (obese with BED [obese -BED; n=13] and obese with no BED [obese non-BED; n=29]) selected via ads. Two blood oxygenated level dependent (BOLD) signal contrast maps were examined: food versus nonfood, and HEPF versus LEUF. In addition, score differences on the disinhibition scale were correlated with BOLD signals...
November 8, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/29118561/pilot-study-of-the-prevalence-of-binge-eating-disorder-in-non-alcoholic-fatty-liver-disease-patients
#5
Jinyu Zhang, Omair Abbasi, Lev Malevanchik, Neena Mohan, Richard Denicola, Nicholas Tarangelo, Dina Halegoua-De Marzio
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the United States. Binge eating disorder (BED) is the most common form of eating disorder. NAFLD and BED have similar risk factors, including obesity, insulin resistance, and metabolic syndrome. The aim of our study was to examine prevalence of BED in NAFLD patients. Methods: We administered the Binge Eating Scale (BES), a questionnaire validated to screen for BED, to NAFLD patients at our Fatty Liver Center...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29113456/a-systematic-review-of-cost-effectiveness-studies-of-prevention-and-treatment-for-eating-disorders
#6
Long Khanh-Dao Le, Phillipa Hay, Cathrine Mihalopoulos
BACKGROUND: Eating disorders are serious mental disorders and are associated with substantial economic and social burden. The aim of this study is to undertake a systematic review of the cost-effectiveness studies of both preventive and treatment interventions for eating disorder. METHOD: Electronic databases (including the Cochrane Controlled Trial Register, MEDLINE, PsycINFO, Academic Search Complete, Global Health, CINAHL complete, Health Business Elite, Econlit, Health Policy Reference Center and ERIC) were searched for published cost-effectiveness studies of eating disorder prevention and treatment including papers published up to January 2017...
November 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29105204/emotional-reactivity-and-appraisal-of-food-in-relation-to-eating-disorder-cognitions-and-behaviours-evidence-to-support-the-motivational-conflict-hypothesis
#7
Sarah E Racine, Karen R Hebert, Stephen D Benning
Eating disorders are associated with both negative and positive emotional reactions towards food. Individual eating disorder symptoms may relate to distinct emotional responses to food, which could necessitate tailored treatments based on symptom presentation. We examined associations between eating disorder symptoms and psychophysiological responses to food versus neutral images in 87 college students [mean (SD) age = 19.70 (2.09); mean (SD) body mass index = 23.25(2.77)]. Reflexive and facial electromyography measures tapping negative emotional reactivity (startle blink reflex) and appraisal (corrugator muscle response) as well as positive emotional reactivity (postauricular reflex) and appraisal (zygomaticus muscle response) were collected...
November 3, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/29102367/-the-psychiatric-comorbidity-of-anorexia-nervosa-a-comparative-study-in-a-population-of-french-and-greek-anorexic-patients
#8
M Kountza, G Garyfallos, D Ploumpidis, E Varsou, I Gkiouzepas
OBJECTIVE: The current study had two objectives: (1) to access the psychiatric comorbidity in axis I and axis II (according to DSM-IV) of anorexia nervosa in a sample of 60 anorexic patients; (2) to compare the features of the psychiatric comorbidity between the two groups of French and Greek anorexic patients who participated in the study, as well as to compare some psychological and behavioral aspects of their anorectic psychopathology. METHOD: Sixty anorexic patients, thirty French and thirty Greek, aged between 18 and 60 years, referred for evaluation and therapy at the unit of eating disorders at the "Institut national Marcel-Rivière of the MGEN" (hôpital de La Verrière, France) and at the unit of eating disorders of the First Department of Psychiatry of EGINITIO University Psychiatric Hospital in Athens (Greece), were accessed with the Eating Attitudes Test-26 (EAT26), Eating Disorder Inventory (EDI), Symptom Checklist-90-Revised (SCL90R), Mini International Neuropsychiatric Interview, Version 5...
November 1, 2017: L'Encéphale
https://www.readbyqxmd.com/read/29089145/the-empirical-status-of-the-third-wave-behaviour-therapies-for-the-treatment-of-eating-disorders-a-systematic-review
#9
REVIEW
Jake Linardon, Christopher G Fairburn, Ellen E Fitzsimmons-Craft, Denise E Wilfley, Leah Brennan
Although third-wave behaviour therapies are being increasingly used for the treatment of eating disorders, their efficacy is largely unknown. This systematic review and meta-analysis aimed to examine the empirical status of these therapies. Twenty-seven studies met full inclusion criteria. Only 13 randomized controlled trials (RCT) were identified, most on binge eating disorder (BED). Pooled within- (pre-post change) and between-groups effect sizes were calculated for the meta-analysis. Large pre-post symptom improvements were observed for all third-wave treatments, including dialectical behaviour therapy (DBT), schema therapy (ST), acceptance and commitment therapy (ACT), mindfulness-based interventions (MBI), and compassion-focused therapy (CFT)...
December 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29083224/form-and-formulation-examining-the-distinctiveness-of-body-image-constructs-in-treatment-seeking-patients-with-binge-eating-disorder
#10
Janet A Lydecker, Marney A White, Carlos M Grilo
OBJECTIVE: Body-image disturbance is a core aspect of eating disorders, yet the clinical manifestations of individuals' weight and shape concerns are complex, vary considerably, and are poorly understood by clinicians and researchers. This study aimed to distinguish different aspects of body-image disturbance-including weight/shape dissatisfaction, weight/shape overvaluation, weight/shape preoccupation, and fear of weight gain-in patients with binge-eating disorder (BED). Examining how each specific body image construct relates to biopsychosocial features of BED could contribute to the refinement of conceptualization and treatment planning...
November 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29083223/the-efficacy-of-cognitive-behavioral-therapy-for-eating-disorders-a-systematic-review-and-meta-analysis
#11
Jake Linardon, Tracey D Wade, Xochitl de la Piedad Garcia, Leah Brennan
OBJECTIVE: This meta-analysis examined the efficacy of cognitive-behavioral therapy (CBT) for eating disorders. METHOD: Randomized controlled trials of CBT were searched. Seventy-nine trials were included. RESULTS: Therapist-led CBT was more efficacious than inactive (wait-lists) and active (any psychotherapy) comparisons in individuals with bulimia nervosa and binge eating disorder. Therapist-led CBT was most efficacious when manualized CBT-BN or its enhanced version was delivered...
November 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29078155/predictors-of-long-term-recovery-in-anorexia-nervosa-and-bulimia-nervosa-data-from-a-22-year-longitudinal-study
#12
Debra L Franko, Nassim Tabri, Aparna Keshaviah, Helen B Murray, David B Herzog, Jennifer J Thomas, Kathryn Coniglio, Pamela K Keel, Kamryn T Eddy
OBJECTIVE: The objective of this study was to investigate predictors of long-term recovery from eating disorders 22 years after entry into a longitudinal study. METHOD: One hundred and seventy-six of the 228 surviving participants (77.2%) were re-interviewed 20-25 years after study entry using the Longitudinal Interval Follow-up Evaluation to assess ED recovery. The sample consisted of 100 women diagnosed with anorexia nervosa (AN) and 76 with bulimia nervosa (BN) at study entry...
October 16, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29075493/perceptions-of-eating-disorder-diagnoses-and-body-image-issues-in-four-male-cases-in-singapore
#13
Evelyn Boon, Kelly Ann Zainal, Stephen W Touyz
BACKGROUND: Despite the increasing number of patients presenting for treatment, little is still known about male eating disorders cases. The current study presents four male eating disorder cases presented to our specialized treatment facility in Singapore. CASE PRESENTATION: Cases 1, 2 and 3 are homosexual males in their twenties and thirties who presented with anorexia nervosa and bulimia nervosa. Case 4 is a heterosexual male in his twenties diagnosed with binge eating disorder...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/29072522/role-of-impulsivity-and-reward-in-the-anti-obesity-actions-of-5-ht2c-receptor-agonists
#14
Guy A Higgins, Fiona D Zeeb, Paul J Fletcher
The selective 5-HT2C receptor agonist lorcaserin entered clinical obesity trials with the prevalent view that satiety was a primary mechanism of action. Subsequent Phase II and III trials demonstrated efficacy in terms of weight loss, although the overall effect size (~3% placebo-corrected change) is considered modest. Lorcaserin has been approved by the FDA for the treatment of obesity with lifestyle modification, but since its introduction in 2013 its sales are in decline, probably due to its overall modest effect...
October 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29057605/putative-risk-factors-for-non-suicidal-self-injury-in-eating-disorders
#15
Ana Isabel Vieira, Bárbara C Machado, Paulo P P Machado, Isabel Brandão, António Roma-Torres, Sónia Gonçalves
Evidence suggests a common association between eating disorders (EDs) and non-suicidal self-injury (NSSI). The present study aimed to investigate the potential risk factors for NSSI among ED patients. We assessed 245 ED patients with the Oxford Risk Factor Interview for ED. The results showed that 33% of ED patients reported NSSI in their lifetime. NSSI appeared to occur more frequently among binge eating/purging type ED patients than among patients with other ED and to be related to a more severe eating pathology...
November 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/29053927/safety-of-pharmacotherapy-options-for-bulimia-nervosa-and-binge-eating-disorder
#16
Nicholas T Bello, Bryn L Yeomans
Eating disorders represent a set of psychiatric illnesses with lifelong complications and high relapse rates. Individuals with eating disorders are often stigmatized and clinicians have a limited set of treatments options. Pharmacotherapy has the potential to improve long term compliance and patient commitment to treatment for eating disorders. Areas Covered: This review will examine the efficacy and safety profile of the FDA-approved medications for the treatment of bulimia nervosa (BN) and binge eating disorder (BED)...
October 20, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/29052240/testing-predictions-of-the-emotion-regulation-model-of-binge-eating-disorder
#17
Therese E Kenny, Christopher Singleton, Jacqueline C Carter
OBJECTIVE: The emotion regulation (ER) model of binge eating posits that individuals with binge-eating disorder (BED) experience more intense emotions and greater difficulties in ER than individuals without BED, leading them to binge eat as a means of regulating emotions. According to this model, individuals with BED should report greater difficulties in ER than their non-BED counterparts, the severity of these difficulties should be positively associated with BED symptoms, and this association should be stronger when individuals experience persistent negative emotions (i...
October 20, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29044551/disordered-eating-and-obesity-associations-between-binge-eating-disorder-night-eating-syndrome-and-weight-related-comorbidities
#18
REVIEW
Courtney McCuen-Wurst, Madelyn Ruggieri, Kelly C Allison
Binge-eating disorder (BED) and night-eating syndrome (NES) are two forms of disordered eating associated with overweight and obesity. While these disorders also occur in nonobese persons, they seem to be associated with weight gain over time and higher risk of diabetes and other metabolic dysfunction. BED and NES are also associated with higher risk of psychopathology, including mood, anxiety, and sleep problems, than those of similar weight status without disordered eating. Treatments are available, including cognitive behavior therapy (CBT), interpersonal psychotherapy, lisdexamfetamine, and selective serotonin reuptake inhibitors (SSRIs) for BED; and CBT, SSRIs, progressive muscle relaxation, and bright light therapy for NES...
October 16, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29038069/study-protocol-and-rationale-for-a-randomized-double-blinded-crossover-trial-of-phentermine-topiramate-er-versus-placebo-to-treat-binge-eating-disorder-and-bulimia-nervosa
#19
Shebani Sethi Dalai, Sarah Adler, Thomas Najarian, Debra Lynn Safer
INTRODUCTION: Bulimia nervosa (BN) and binge eating disorder (BED) are associated with severe psychological and medical consequences. Current therapies are limited, leaving up to 50% of patients symptomatic despite treatment, underscoring the need for additional treatment options. Qsymia, an FDA-approved medication for obesity, combines phentermine and topiramate ER. Topiramate has demonstrated efficacy for both BED and BN, but limited tolerability. Phentermine is FDA-approved for weight loss...
October 14, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29032922/serotonin-transporter-density-in-binge-eating-disorder-and-pathological-gambling-a-pet-study-with-11-c-madam
#20
Joonas Majuri, Juho Joutsa, Jarkko Johansson, Valerie Voon, Riitta Parkkola, Hannu Alho, Eveliina Arponen, Valtteri Kaasinen
Behavioral addictions, such as pathological gambling (PG) and binge eating disorder (BED), appear to be associated with specific changes in brain dopamine and opioid function, but the role of other neurotransmitter systems is less clear. Given the crucial role of serotonin in a number of psychiatric disorders, we aimed to compare brain serotonergic function among individuals with BED, PG and healthy controls. Seven BED patients, 13 PG patients and 16 healthy controls were scanned with high-resolution positron emission tomography (PET) using the serotonin transporter (SERT) tracer [(11)C]MADAM...
October 9, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
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