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https://www.readbyqxmd.com/read/28434187/ultrasound-guided-intra-articular-injection-of-the-radio-ulnar-radio-humeral-joints-and-ultrasound-guided-dry-needling-of-the-affected-limb-muscles-to-relieve-fixed-pronation-deformity-and-myofascial-issues-around-the-shoulder-in-a-case-of-complex-regional
#1
Renuka Pai, Lakshmi Vas
BACKGROUND: Complex Regional Pain Syndrome (CRPS) occurs due to different pathophysiological mechanisms. Presently there is no description of definitive treatment that can resolve the especially recalcitrant motor issues of disability in CRPS-1. CASE REPORT: We have herein described the successful management of motor disability with a multi-modal approach in a patient with CRPS-1 that occurred as a result of a fracture sustained in the lower end of the radius. Sensory/sudomotor/vasomotor symptoms were relieved completely by medications and stellate ganglion block, in two weeks...
April 23, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28434173/the-effect-of-resilience-on-task-persistence-and-performance-during-repeated-exposure-to-heat-pain
#2
P Maxwell Slepian, Christopher R France
The Pain Resilience Scale was recently developed to assess dimensions of resilience critical to pain-related adaptation and was found to predict experimental pain sensitivity in a pain-free population. Pain resilience has also been theoretically linked to behavioral persistence despite pain. To date, however, this hypothesis has not been experimentally tested. To address this gap in the literature, in the current study 105 healthy young adults underwent a baseline administration of the Paced Auditory Serial Addition Test (PASAT), a stressful mental arithmetic task, delivered with somatosensory distraction (i...
April 22, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28434165/connexin-hemichannels-in-astrocytes-an-assessment-of-controversies-regarding-their-functional-characteristics
#3
Brian Skriver Nielsen, Daniel Bloch Hansen, Bruce R Ransom, Morten Schak Nielsen, Nanna MacAulay
Astrocytes in the mammalian central nervous system are interconnected by gap junctions made from connexins of the subtypes Cx30 and Cx43. These proteins may exist as hemichannels in the plasma membrane in the absence of a 'docked' counterpart on the neighboring cell. A variety of stimuli are reported to open the hemichannels and thereby create a permeation pathway through the plasma membrane. Cx30 and Cx43 have, in their hemichannel configuration, been proposed to act as ion channels and membrane pathways for different molecules, such as fluorescent dyes, ATP, prostaglandins, and glutamate...
April 22, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28434164/microglia-loss-contributes-to-the-development-of-major-depression-induced-by-different-types-of-chronic-stresses
#4
Lijuan Tong, Yu Gong, Peng Wang, Wenfeng Hu, Jili Wang, Zhuo Chen, Wei Zhang, Chao Huang
Recently, the loss and dystrophy of hippocampal microglia induced by chronic unpredictable stress (CUS) has been reported to mediate the development of major depression in mice whose microglial cells were labeled with enhanced green fluorescent protein-conjuncted-CX3C receptor type 1. However, whether this happens in endogenous microglia with no genetic intervention remains unclear. Here, we addressed this issue in mice treated with different types of chronic stresses, including the CUS, chronic restraint stress (CRS) and chronic social defeat stress (CSDS)...
April 22, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28434163/biomarkers-of-epileptogenesis-the-focus-on-glia-and-cognitive-dysfunctions
#5
Annamaria Vezzani, Rosaria Pascente, Teresa Ravizza
The need to find measures that reliably predict the onset of epilepsy after injurious events or how the patient will respond to anti-seizure drugs led to intensive pre-clinical and clinical research to discover non-invasive biomarkers that could increase the sensitivity of existing clinical indicators. The use of experimental models of epileptogenesis and of drug-resistance is instrumental to select the most promising approaches to explore such biomarkers in the pre-clinical setting for further clinical validation...
April 22, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28434144/peer-coaching-interventions-for-parents-of-children-with-type-1-diabetes
#6
REVIEW
Carrie Tully, Caitlin Shneider, Maureen Monaghan, Marisa E Hilliard, Randi Streisand
PURPOSE OF REVIEW: Peer support is a promising model of providing psychosocial support to parents of children with type 1 diabetes. This review seeks to discuss the findings of the existing literature in peer coaching as it relates to parents and diabetes as well as to identify gaps in knowledge for future intervention development and implementation. RECENT FINDINGS: Peer support programs vary widely with regard to recruitment, training, and delivery protocols. Across most programs, ongoing support and supervision are provided to peer coaches...
June 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28434123/conversion-disorder-functional-neurological-symptom-disorder-and-chronic-pain-comorbidity-assessment-and-treatment
#7
REVIEW
Patricia Tsui, Andrew Deptula, Derek Y Yuan
PURPOSE OF REVIEW: This paper examines the overlap of conversion disorder with chronic pain conditions, describes ways to assess for conversion disorder, and provides an overview of evidence-based treatments for conversion disorder and chronic pain, with a focus on conversion symptoms. RECENT FINDINGS: Conversion disorder is a significant problem that warrants further study, given that there are not many well-established guidelines. Accurate and timely assessment should help move treatment in a more fruitful direction and avoid unnecessary medical interventions...
June 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28434107/early-life-obesity-prevention-critique-of-intervention-trials-during-the-first-one-thousand-days
#8
REVIEW
John J Reilly, Anne Martin, Adrienne R Hughes
PURPOSE OF REVIEW: To critique the evidence from recent and ongoing obesity prevention interventions in the first 1000 days in order to identify evidence gaps and weaknesses, and to make suggestions for more informative future intervention trials. RECENT FINDINGS: Completed and ongoing intervention trials have had fairly modest effects, have been limited largely to high-income countries, and have used relatively short-term interventions and outcomes. Comparison of the evidence from completed prevention trials with the evidence from systematic reviews of behavioral risk factors shows that some life-course stages have been neglected (pre-conception and toddlerhood), and that interventions have neglected to target some important behavioral risk factors (maternal smoking during pregnancy, infant and child sleep)...
April 22, 2017: Current Obesity Reports
https://www.readbyqxmd.com/read/28434106/what-do-patients-want-to-know-about-contraception-and-which-method-would-they-prefer
#9
Patricia G Oppelt, Friederike Baier, Christine Fahlbusch, Katharina Heusinger, Thomas Hildebrandt, Christiane Breuel, Ralf Dittrich
PURPOSE: The aim of this study was to determine the extent to which women's choice of contraceptive method depends on the advice received from their gynecologist and whether more intensive counseling might lead to more frequent use of long-acting reversible contraception (LARC). METHODS: A total of 1089 physicians and 18,521 women responded to 32 or 37 questions, respectively, using an online questionnaire. The women were asked about their current use of contraceptive methods, the extent of their satisfaction with them, their satisfaction with the counseling they had received, and whether they wanted to have more information about contraception...
April 22, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28434092/cyberbullying-victimization-and-adolescent-mental-health-evidence-of-differential-effects-by-sex-and-mental-health-problem-type
#10
Soyeon Kim, Scott R Colwell, Anna Kata, Michael H Boyle, Katholiki Georgiades
The use of electronic communication technologies has become a core method for adolescent communication. While there are many benefits to such technologies, cyberbullying has emerged as a potential harm. This study examines the association between cyberbullying and adolescent mental health problems and the extent to which this association differs by sex and mental health problem type. A clustered sample of 31,148 students in grades 6-12 (Female = 51.9%; 56.5% Caucasian, 10.2% South Asian) completed an anonymous survey asking their frequency of exposure to traditional forms of bullying, cyberbullying, and experiences of mental health problems over the past 6 months...
April 22, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28434076/%C3%AE-synuclein-nonhuman-primate-models-of-parkinson-s-disease
#11
REVIEW
David J Marmion, Jeffrey H Kordower
Proper understanding of the mechanism(s) by which α-synuclein misfolds and propagates may hold the key to unraveling the complex pathophysiology of Parkinson's disease. A more complete understanding of the disease itself, as well as establishing animal models that fully recapitulate pathological and functional disease progression, are needed to develop treatments that will delay, halt or reverse the disease course. Traditional neurotoxin-based animal models fail to mimic crucial aspects of Parkinson's and thus are not relevant for the study of neuroprotection and disease-modifying therapies...
April 22, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28434056/beyond-the-primary-endpoint-paradigm-a-test-of-intervention-effect-in-hiv-behavioral-intervention-trials-with-numerous-correlated-outcomes
#12
Jessica M Harwood, Robert E Weiss, W Scott Comulada
Behavioral interventions are increasingly based on holistic approaches to health with an understanding that health-related behaviors are linked. A motivating example is provided by the Philani study, an intervention trial conducted to improve the health of South African mothers and their children. Inter-related health problems around maternal alcohol use, malnutrition, and HIV were addressed; multiple endpoints were targeted. The traditional hypothesis testing paradigm that tests significance on one primary outcome did not suffice...
April 22, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/28434045/slow-drilling-speeds-for-single-drill-implant-bed-preparation-experimental-in-vitro-study
#13
R A Delgado-Ruiz, E Velasco Ortega, G E Romanos, S Gerhke, I Newen, J L Calvo-Guirado
AIMS: To evaluate the real-time bone temperature changes during the preparation of the implant bed with a single-drill protocol with different drill designs and different slow drilling speeds in artificial type IV bone. MATERIALS AND METHODS: For this experimental in vitro study, 600 implant bed preparations were performed in 10 bovine bone disks using three test slow drilling speeds (50/150/300 rpm) and a control drilling speed (1200 rpm). The temperature at crestal and apical areas and time variations produced during drilling with three different drill designs with similar diameter and length but different geometry were recorded with real-life thermographic analysis...
April 22, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28433943/acute-lung-injury-leads-to-depression-like-symptoms-through-upregulation-of-neutrophilic-and-neuronal-nadph-oxidase-signaling-in-a-murine-model
#14
Ahmed Nadeem, Nahid Siddiqui, Naif O Al-Harbi, Sabry M Attia, Shakir D AlSharari, Sheikh F Ahmad
There is an increased prevalence of comorbid major depressive disorders with a number of inflammatory conditions which is thought to result from activation of the immune system. Acute lung injury (ALI) in humans has been also shown to be associated with depression previously. However, no study has explored the mechanism behind ALI-induced depression. NADPH oxidase (NOX-2) derived reactive oxygen species (ROS) are associated with neuropsychiatric disorders including depression. ROS generation via NOX-2 is also shown to be involved in the pathogenesis of ALI...
April 20, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28433942/synthesis-and-characterization-of-poly-propylene-imine-dendrimer-grafted-gold-nanoparticles-as-nanocarriers-of-doxorubicin
#15
Marzieh Golshan, Mehdi Salami-Kalajahi, Mina Mirshekarpour, Hossein Roghani-Mamaqani, Maryam Mohammadi
The aim of current work is synthesis 4th-generation-poly(propylene imine) (PPI)-dendrimer modified gold nanoparticles (Au-G4A) as nanocarriers for doxorubicin (DOX) and studying in vitro drug release kinetics from nanocarriers into different media. Accordingly, AuNPs were synthesized by reduction of chloroauric acid (HAuCl4) aqueous solution with trisodium citrate and modified with cysteamine to obtain amine-functionalized (Au-NH2) nanoparticles. Au-NH2 nanoparticles were used as multifunctional cores and participated in Michael addition of acrylonitrile and reduction process by lithium aluminum hydride (LAH) to synthesize Au-G4A nanoparticles...
April 13, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28433936/sustained-viral-gene-delivery-from-a-micro-fibrous-elastomeric-cardiac-patch-to-the-ischemic-rat-heart
#16
Xinzhu Gu, Yasumoto Matsumura, Ying Tang, Souvik Roy, Richard Hoff, Bing Wang, William R Wagner
Biodegradable and elastomeric patches have been applied to the surface of infarcted hearts as temporary mechanical supports to effectively alter adverse left ventricular remodeling processes. In this report, recombinant adeno-associated virus (AAV), known for its persistent transgene expression and low pathogenicity, was incorporated into elastomeric polyester urethane urea (PEUU) and polyester ether urethane urea (PEEUU) and processed by electrospinning into two formats (solid fibers and core-sheath fibers) designed to influence the controlled release behavior...
April 14, 2017: Biomaterials
https://www.readbyqxmd.com/read/28433908/steam-torrefaction-of-eucalyptus-globulus-for-producing-black-pellets-a-pilot-scale-experience
#17
Luis E Arteaga-Pérez, Héctor Grandón, Mauricio Flores, Cristina Segura, Stephen S Kelley
Steam torrefaction of Eucalyptus globulus was performed at temperatures between 245°C and 265°C in a 100kg/h pilot plant. Torrefied biomass was then pelletized in a 300kg/h unit and the pellets were subject to durability, density and combustion tests. The structural changes measured with FTIR were studied along with the combustion behavior of the materials. Compositional analysis showed that increasing the torrefaction temperature reduced both hemicellulose fraction and overall mass yield (MY). Furthermore, there was a linear relationship between the energy yield (EY) and mass yield (EY=[1...
April 11, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28433897/low-temperature-microwave-assisted-pyrolysis-of-wood-sawdust-for-phenolic-rich-compounds-kinetics-and-dielectric-properties-analysis
#18
Hu Luo, Liwei Bao, Lingzhao Kong, Yuhan Sun
Microwave-assisted pyrolysis of wood sawdust for phenolic rich compounds was carried out between 400 and 550°C in a batch reactor. An efficient preparation of liquid products was observed at 500°C with a yield of 58.50%, which was similar to conventional fast pyrolysis. The highest concentration of phenolic compounds in liquid product reached up to 78.7% (area) in which the alkoxy phenols contributed 81.8% at 500°C. Microwave thermogravimetric analysis using KAS method was used firstly to investigate the low-temperature pyrolytic behaviors and activation energy...
April 9, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28433895/evaluating-network-level-predictors-of-behavior-change-among-injection-networks-enrolled-in-the-hptn-037-randomized-controlled-trial
#19
Laramie R Smith, Steffanie A Strathdee, David Metzger, Carl Latkin
BACKGROUND: Little is known about ways network-level factors that may influence the adoption of combination prevention behaviors among injection networks, or how network-oriented interventions might moderate this behavior change process. METHODS: A total of 232 unique injection risk networks in Philadelphia, PA, were randomized to a peer educator network-oriented intervention or standard of care control arm. Network-level aggregates reflecting the injection networks' baseline substance use dynamics, social interactions, and the networks exposure to gender- and structural-related vulnerabilities were calculated and used to predict changes in the proportion of network members adopting safer injection practices at 6-month follow-up...
April 5, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28433892/longitudinal-associations-between-the-use-of-sexually-explicit-material-and-adolescents-attitudes-and-behaviors-a-narrative-review-of-studies
#20
Goran Koletić
This review analyzed longitudinal studies examining the effects of sexually explicit material on adolescents' attitudes, beliefs and behaviors. The review also aimed to provide an analysis of the limitations of the existing studies, as well as recommendations for future research. To be included, publications had to employ repeated measurements, include a measure of sexually explicit material use and participants aged 18 years or under. A total of 20 papers from nine different research projects were reviewed...
April 20, 2017: Journal of Adolescence
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