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https://www.readbyqxmd.com/read/28335412/ameliorative-effects-of-neutral-electrolyzed-water-on-growth-performance-biochemical-constituents-and-histopathological-changes-in-turkey-poults-during-aflatoxicosis
#1
Denise Gómez-Espinosa, Francisco Javier Cervantes-Aguilar, Juan Carlos Del Río-García, Tania Villarreal-Barajas, Alma Vázquez-Durán, Abraham Méndez-Albores
Different in vitro and in silico approaches from our research group have demonstrated that neutral electrolyzed water (NEW) can be used to detoxify aflatoxins. The objective of this investigation was to evaluate the ability of NEW to detoxify B-aflatoxins (AFB₁ and AFB₂) in contaminated maize and to confirm detoxification in an in vivo experimental model. Batches of aflatoxin-contaminated maize were detoxified with NEW and mixed in commercial feed. A total of 240 6-day-old female large white Nicholas-700 turkey poults were randomly divided into four treatments of six replicates each (10 turkeys per replicate), which were fed ad libitum for two weeks with the following dietary treatments: (1) control feed containing aflatoxin-free maize (CONTROL); (2) feed containing the aflatoxin-contaminated maize (AF); (3) feed containing the aflatoxin-contaminated maize detoxified with NEW (AF + NEW); and (4) control feed containing aflatoxin-free maize treated with NEW (NEW)...
March 14, 2017: Toxins
https://www.readbyqxmd.com/read/28335404/perceptions-of-health-co-benefits-in-relation-to-greenhouse-gas-emission-reductions-a-survey-among-urban-residents-in-three-chinese-cities
#2
Jinghong Gao, Guozhang Xu, Wenjun Ma, Yong Zhang, Alistair Woodward, Sotiris Vardoulakis, Sari Kovats, Paul Wilkinson, Tianfeng He, Hualiang Lin, Tao Liu, Shaohua Gu, Jun Wang, Jing Li, Jun Yang, Xiaobo Liu, Jing Li, Haixia Wu, Qiyong Liu
Limited information is available on the perceptions of stakeholders concerning the health co-benefits of greenhouse gas (GHG) emission reductions. The purpose of this study was to investigate the perceptions of urban residents on the health co-benefits involving GHG abatement and related influencing factors in three cities in China. Beijing, Ningbo and Guangzhou were selected for this survey. Participants were recruited from randomly chosen committees, following quotas for gender and age in proportion to the respective population shares...
March 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28335317/cytotoxicity-of-silver-nanoparticle-and-chitin-nanofiber-sheet-composites-caused-by-oxidative-stress
#3
Jun Kinoda, Masayuki Ishihara, Hidemi Hattori, Shingo Nakamura, Koichi Fukuda, Hidetaka Yokoe
Size-controlled spherical silver nanoparticles (<10 nm) and chitin-nanofiber sheet composites (Ag NPs/CNFS) have previously been reported to have strong antimicrobial activity in vitro. Although Ag NPs/CNFS have strong antimicrobial activity, their cytotoxicity has not been investigated. This study was performed to evaluate the effects of Ag NPs/CNFS on cytotoxicity for fibroblasts in vitro and healing delay of wound repair in vivo, focused on oxidative stress. Cytotoxic activities of Ag NPs/CNFS were investigated using a fibroblast cell proliferation assay, nitric oxide/nitrogen dioxide (NO/NO₂) measurement of the cell lysates in vitro, inhibitory effects of Ag NPs/CNFS on healing-impaired wound repair using diabetic mice in vivo, 8-hydroxy-2'-deoxyguanosine (8-OHdG) immunohistochemical staining of the skin sections, and generation of carbonyl protein in the wound was performed to evaluate cytotoxicity with oxidative stress...
October 20, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334647/arsenic-load-in-rice-ecosystem-and-its-mitigation-through-deficit-irrigation
#4
Arkabanee Mukherjee, M Kundu, B Basu, B Sinha, M Chatterjee, M Das Bairagya, U K Singh, S Sarkar
Rice the staple food is a notable intake source of arsenic to the rural population of eastern India through food-chain. A field survey was carried out to study the variation of arsenic load in different parts of rice genotype Shatabdi (most popular genotype of the region) exposed to varying level of arsenic present in the irrigation water and soil. As irrigation is the primary source of arsenic contamination, a study was conducted to assess arsenic load in rice ecosystem under deficit irrigation practices like intermittent ponding (IP), saturation (SAT) and aerobic (AER) imposed during stress allowable stage (16-40 days after transplanting) of the crop (genotype Shatabdi)...
March 20, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28334561/determining-current-insulin-pen-use-practices-and-errors-in-the-inpatient-setting
#5
Katelyn E Brown, John B Hertig
BACKGROUND: The use of insulin pens in the inpatient setting has continued to be a controversial decision. Insulin pens provide several advantages, but given significant reports of medication errors, several organizations have issued alerts to caution users about safety concerns. A survey was conducted to assess the prevalence of insulin pen use and current utilization trends in the inpatient setting. METHODS: The 31-question guided-logic survey was developed based on review of primary literature regarding insulin pen utilization and evaluated by a panel of medication safety experts from a variety of health care settings...
December 2016: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28334452/quantitative-assessment-of-the-risk-of-release-of-foot-and-mouth-disease-virus-via-export-of-bull-semen-from-israel
#6
A Meyer, L Zamir, A Ben Yair Gilboa, B Gelman, D U Pfeiffer, T Vergne
Various foot-and-mouth disease (FMD) virus strains circulate in the Middle East, causing frequent episodes of FMD outbreaks among Israeli livestock. Since the virus is highly resistant in semen, artificial insemination with contaminated bull semen may lead to the infection of the receiver cow. As a non-FMD-free country with vaccination, Israel is currently engaged in trading bull semen only with countries of the same status. The purpose of this study was to assess the risk of release of FMD virus through export of bull semen in order to estimate the risk for FMD-free countries considering purchasing Israeli bull semen...
March 23, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28333985/the-role-of-above-ground-competition-and-nitrogen-vs-phosphorus-enrichment-in-seedling-survival-of-common-european-plant-species-of-semi-natural-grasslands
#7
Tobias Ceulemans, Eva Hulsmans, Sigi Berwaers, Kasper Van Acker, Olivier Honnay
Anthropogenic activities have severely altered fluxes of nitrogen and phosphorus in ecosystems worldwide. In grasslands, subsequent negative effects are commonly attributed to competitive exclusion of plant species following increased above-ground biomass production. However, some studies have shown that this does not fully account for nutrient enrichment effects, questioning whether lowering competition by reducing grassland productivity through mowing or herbivory can mitigate the environmental impact of nutrient pollution...
2017: PloS One
https://www.readbyqxmd.com/read/28333974/interaction-between-allee-effects-caused-by-organism-environment-feedback-and-by-other-ecological-mechanisms
#8
Lijuan Qin, Feng Zhang, Wanxiong Wang, Weixin Song
Understanding Allee effect has crucial importance for ecological conservation and management because it is strongly related to population extinction. Due to various ecological mechanisms accounting for Allee effect, it is necessary to study the influence of multiple Allee effects on the dynamics and persistence of population. We here focus on organism-environment feedback which can incur strong, weak, and fatal Allee effect (AE-by-OEF), and further examine their interaction with the Allee effects caused by other ecological mechanisms (AE-by-OM)...
2017: PloS One
https://www.readbyqxmd.com/read/28333867/determining-risk-of-severe-gastrointestinal-toxicity-based-on-pretreatment-gut-microbial-community-in-patients-receiving-cancer-treatment-a-new-predictive-strategy-in-the-quest-for-personalized-cancer-medicine
#9
Hannah R Wardill, Wim J E Tissing
PURPOSE OF REVIEW: Currently, our ability to accurately predict a patient's risk of developing severe gastrointestinal toxicity from their cancer treatment is limited. Risk stratification continues to rely on traditional patient-related and treatment-related factors including age, ethnicity, sex, comorbidities, genetics, agent, dose and schedule. Although informative, these crude measures continue to underestimate toxicity risk, and hence alternative methods of risk prediction must be investigated...
March 22, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/28333071/combined-effects-of-curcumin-and-lycopene-or-bixin-in-yoghurt-on-inhibition-of-ldl-oxidation-and-increases-in-hdl-and-paraoxonase-levels-in-streptozotocin-diabetic-rats
#10
Renata Pires Assis, Carlos Alberto Arcaro, Vânia Ortega Gutierres, Juliana Oriel Oliveira, Paulo Inácio Costa, Amanda Martins Baviera, Iguatemy Lourenço Brunetti
Combination therapy using natural antioxidants to manage diabetes mellitus and its complications is an emerging trend. The aim of this study was to investigate the changes promoted by treatment of streptozotocin (STZ)-diabetic rats with yoghurt enriched with the bioactives curcumin, lycopene, or bixin (the latter two being carotenoids). Antioxidants were administered individually, or as mixtures, and biomarkers of metabolic and oxidative disturbances, particularly those associated with cardiovascular risk, were assessed...
March 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28332850/integrating-molecular-control-to-improve-cryopreservation-outcome
#11
John G Baust, Kristi K Snyder, Robert Van Buskirk, John M Baust
Cryopreservation (CP) is a critical component in enabling on-demand access to biological material (macromolecules, cells, and tissues), yet CP has evolved little over the last several decades. Today's CP processes often yield a suboptimal "product," which has slowed progression in areas such as cell therapy and stem cell research. Recent discoveries focusing on molecular control and buffering of cell stress responses to CP as well as the development of new devices that improve sample freezing and thawing are now providing a path to improve sample quality...
March 23, 2017: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/28332697/alpha-1-antitrypsin-inhibits-rankl-induced-osteoclast-formation-and-functions
#12
Mohammad Ahsanul Akbar, David Nardo, Mong-Jen Chen, Ahmed S Elshikha, Rubina Ahamed, Eslam M Elsayed, Claire Bigot, Lexie Shannon Holliday, Sihong Song
Osteoporosis is a global public health problem affecting more than 200 million people worldwide. We previously showed that treatment with alpha-1 antitrypsin (AAT), a multifunctional protein with anti-inflammatory properties, mitigated bone loss in an ovariectomized mouse model. However, the underlying mechanisms of the protective effect of AAT on bone tissue are largely unknown. In this study, we investigated the effect of AAT on osteoclast formation and function in vitro. Our results showed that AAT dose-dependently inhibited the formation of RANKL (receptor activator of nuclear factor κB ligand) induced osteoclasts derived from mouse bone marrow macrophages/monocyte (BMM) lineage cells and the murine macrophage cell line, RAW 264...
March 21, 2017: Molecular Medicine
https://www.readbyqxmd.com/read/28332578/a-new-class-of-inhibitors-of-the-arac-family-virulence-regulator-vibrio-cholerae-toxt
#13
Anne K Woodbrey, Evans O Onyango, Maria Pellegrini, Gabriela Kovacikova, Ronald K Taylor, Gordon W Gribble, F Jon Kull
Vibrio cholerae is responsible for the diarrheal disease cholera that infects millions of people worldwide. While vaccines protecting against cholera exist, and oral rehydration therapy is an effective treatment method, the disease will remain a global health threat until long-term solutions such as improved sanitation and access to clean water become widely available. Because of this, there is a pressing need for potent therapeutics that can either mitigate cholera symptoms, or act prophylactically to prevent the virulent effects of a cholera infection...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28332469/marrying-step-feed-with-clarifier-improvements-increase-wet-weather-capacity-integrated-methodology
#14
Glen T Daigger John S Siczka Thomas F Smith David A Frank J A McCorquodale
The need to increase the peak wet weather secondary treatment capacity of the City of Akron, OH, Water Reclamation Facility (WRF) provided the opportunity to test an integrated methodology for maximizing the peak wet weather secondary treatment capacity of activated sludge systems. An initial investigation, consisting of process modeling of the secondary treatment system and computational fluid dynamics (CFD) analysis of the existing relatively shallow secondary clarifiers (3.3 and 3.7 m sidewater depth in 30...
March 22, 2017: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28332460/framing-the-tax-and-health-nexus-a-neglected-aspect-of-public-health-concern
#15
David Mccoy, Simukai Chigudu, Taavi Tillmann
Previous studies have described various associations between tax policy and health. Here we propose a unifying conceptual framework of 'Five R's' to stimulate awareness about the importance of tax to health improvement. First, tax can improve representation and democratic accountability, and help make governments more responsive to the needs of its citizens. Second, tax can create a revenue stream for a universal pool of public finance for health care and other public services. Third, progressive taxation when combined with appropriate public spending can help redistribute wealth and income and mitigate social and health inequalities...
April 2017: Health Economics, Policy, and Law
https://www.readbyqxmd.com/read/28332126/klotho-suppresses-high-phosphate-induced-osteogenic-responses-in-human-aortic-valve-interstitial-cells-through-inhibition-of-sox9
#16
Fei Li, Qingzhou Yao, Lihua Ao, Joseph C Cleveland, Nianguo Dong, David A Fullerton, Xianzhong Meng
Elevated level of blood phosphate (Pi) associated with chronic kidney disease (CKD) is a risk factor of aortic valve calcification. Aortic valve interstitial cells (AVICs) display osteogenic responses to high Pi although the underlying mechanism is incompletely understood. Sox9 is a pro-chondrogenic factor and may play a role in ectopic tissue calcification. Circulating and kidney levels of Klotho are reduced in patients with CKD. We hypothesized that Sox9 mediates high Pi-induced osteogenic responses in human AVICs and that Klotho inhibits the responses...
March 22, 2017: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/28332086/reducing-nitrogen-losses-through-ammonia-volatilization-and-surface-runoff-to-improve-apparent-nitrogen-recovery-of-double-cropping-of-late-rice-using-controlled-release-urea
#17
Pengfei Li, Jianwei Lu, Wenfeng Hou, Yonghui Pan, Yang Wang, Muhammad Rizwan Khan, Tao Ren, Rihuan Cong, Xiaokun Li
Controlled release fertilizer can reduce nitrogen losses to the environment while increasing grain yield and improving apparent nitrogen recovery (ANR) of rice. However, few studies have evaluated the comparative efficacy of different polymer-coated urea products on nitrogen (N) losses, ANR, and N uptake of rice. A 2-year field experiment was conducted to compare the effects of three different types of polymer-coated urea fertilizer on nitrogen losses through NH3 volatilization and surface runoff to the environment, ANR, grain yield, and N uptake as compared to conventional urea of rice...
March 22, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28331889/unsupervised-labeling-of-glomerular-boundaries-using-gabor-filters-and-statistical-testing-in-renal-histology
#18
Brandon Ginley, John E Tomaszewski, Rabi Yacoub, Feng Chen, Pinaki Sarder
The glomerulus is the blood filtering unit of the kidney. Each human kidney contains [Formula: see text] glomeruli. Several renal conditions originate from structural damage to glomerular microcompartments, such as proteinuria, the excessive loss of blood proteins into urine. The gold standard for evaluating structural damage in renal pathology is histopathological and immunofluorescence examination of needle biopsies under a light microscope. This method is limited by qualitative or semiquantitative manual scoring approaches to the evaluation of glomerular structural features...
April 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28331552/bioenergy-production-and-sustainable-development-science-base-for-policymaking-remains-limited
#19
REVIEW
Carmenza Robledo-Abad, Hans-Jörg Althaus, Göran Berndes, Simon Bolwig, Esteve Corbera, Felix Creutzig, John Garcia-Ulloa, Anna Geddes, Jay S Gregg, Helmut Haberl, Susanne Hanger, Richard J Harper, Carol Hunsberger, Rasmus K Larsen, Christian Lauk, Stefan Leitner, Johan Lilliestam, Hermann Lotze-Campen, Bart Muys, Maria Nordborg, Maria Ölund, Boris Orlowsky, Alexander Popp, Joana Portugal-Pereira, Jürgen Reinhard, Lena Scheiffle, Pete Smith
The possibility of using bioenergy as a climate change mitigation measure has sparked a discussion of whether and how bioenergy production contributes to sustainable development. We undertook a systematic review of the scientific literature to illuminate this relationship and found a limited scientific basis for policymaking. Our results indicate that knowledge on the sustainable development impacts of bioenergy production is concentrated in a few well-studied countries, focuses on environmental and economic impacts, and mostly relates to dedicated agricultural biomass plantations...
March 2017: Global Change Biology. Bioenergy
https://www.readbyqxmd.com/read/28331551/environmental-costs-and-benefits-of-growing-miscanthus-for-bioenergy-in-the-uk
#20
REVIEW
Jon P McCalmont, Astley Hastings, Niall P McNamara, Goetz M Richter, Paul Robson, Iain S Donnison, John Clifton-Brown
Planting the perennial biomass crop Miscanthus in the UK could offset 2-13 Mt oil eq. yr(-1), contributing up to 10% of current energy use. Policymakers need assurance that upscaling Miscanthus production can be performed sustainably without negatively impacting essential food production or the wider environment. This study reviews a large body of Miscanthus relevant literature into concise summary statements. Perennial Miscanthus has energy output/input ratios 10 times higher (47.3 ± 2.2) than annual crops used for energy (4...
March 2017: Global Change Biology. Bioenergy
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