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https://www.readbyqxmd.com/read/28449467/clinical-analysis-on-113-patients-with-lung-cancer-treated-by-percutaneous-ct-guided-microwave-ablation
#1
Lou Zhong, Siyuan Sun, Jiahai Shi, Fei Cao, Xiao Han, Xueping Bao, Qingsheng You
BACKGROUND: Lung Cancer is a primary tumor with poor prognosis. For early stage lung cancer, treatment options include surgical resection and microwave techniques. Percutaneous ablative techniques emerged as best therapeutic options for nonsurgical patients. METHODS: The aim of this study was to retrospectively analyze the clinical effect of CT-guided microwave ablation (MWA) treatment for patients with lung cancer who were not eligible for surgical resection. MWA was used to treat the tumor lesion of 113 patients with lung cancer who were in our hospital from Jan, 2013 to Jun, 2015...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449363/health-literacy-interventions-for-immigrant-populations-a-systematic-review
#2
REVIEW
M Fernández-Gutiérrez, P Bas-Sarmiento, M J Albar-Marín, O Paloma-Castro, J M Romero-Sánchez
BACKGROUND: Health literacy is considered a social health determinant that influences improvement in health, patient empowerment and reduction in inequalities. There is a lack of health literacy interventions for vulnerable social groups (i.e. immigrants), and nurses have shown little familiarity with the concept. AIM: This study aimed to identify and analyse whether interventions directed at immigrant populations improve the functional (basic reading, writing and arithmetic skills), interactive (social and cognitive skills) and critical (advanced cognitive and social skills in critically analyzing information and making informed decisions) dimensions of health literacy, taking into account the role played by nursing in these interventions...
April 27, 2017: International Nursing Review
https://www.readbyqxmd.com/read/28449285/research-review-childhood-chronic-physical-illness-and-adult-emotional-health-a-systematic-review-and-meta-analysis
#3
REVIEW
Ekin Secinti, Ellen J Thompson, Marcus Richards, Darya Gaysina
BACKGROUND: Childhood chronic physical illness is associated with a greater vulnerability for emotional problems (i.e. depression and anxiety) in childhood. However, little is known about life-long effects of childhood chronic physical illness on mental health. The present study aims to systematically review evidence for associations between eight chronic physical illnesses with childhood onset (arthritis, asthma, cancer, chronic renal failure, congenital heart disease, cystic fibrosis, type 1 diabetes, and epilepsy) and adult emotional problems...
April 27, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28449279/review-of-the-strengths-and-difficulties-questionnaire-translated-into-languages-spoken-by-children-and-adolescents-of-refugee-background
#4
Yvonne Stolk, Ida Kaplan, Josef Szwarc
The Strengths and Difficulties Questionnaire (SDQ), routinely used to screen for children's and adolescents' emotional and behavioural problems, has been translated into at least 80 languages. As children of refugee background are particularly vulnerable to mental health problems resulting from their refugee experiences, this review examines whether SDQs translated into languages spoken by major refugee groups are validated and culturally equivalent to the original SDQ and sensitive to change following interventions...
April 27, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/28449262/predictive-mechanisms-linking-brain-opioids-to-chronic-pain-vulnerability-and-resilience
#5
REVIEW
Anthony Kenneth Peter Jones, Christopher Andrew Brown
Chronic pain is a major global healthcare problem that is currently inadequately treated. In addition, the current use of opioids for treatment has reached far beyond the paucity of evidence for long-term benefits relative to risks. Benefit-risk models for opioid and non-opioid treatments would benefit from a rational, mechanism-based understanding of neuroplastic and neurochemical contributions to chronic pain. Here we evaluate the findings and limitations of representative research investigating brain neuroplasticity and neurochemistry in chronic pain...
April 27, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28449200/species-traits-as-predictors-of-range-shifts-under-contemporary-climate-change-a-review-and-meta-analysis
#6
Sarah A MacLean, Steven R Beissinger
A growing body of literature seeks to explain variation in range shifts using species' ecological and life history traits, with expectations that shifts should be greater in species with greater dispersal ability, reproductive potential, and ecological generalization. Despite strong theoretical support for species' traits as predictors of range shifts, empirical evidence from contemporary range shift studies remains limited in extent and consensus. We conducted the first comprehensive review of species' traits as predictors of range shifts, collecting results from 51 studies across multiple taxa encompassing over 11,000 species' responses for 54 assemblages of taxonomically-related species occurring together in space...
April 27, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28449054/i-learn-therefore-i-am-a-phenomenological-analysis-of-meanings-of-lifelong-learning-for-vulnerable-older-adults
#7
Miya Narushima, Jian Liu, Naomi Diestelkamp
Background and Objectives: This study explores the lifelong learning experience of vulnerable older adults to find out (a) what is involved in their activities, (b) what meanings they take from their learning, and (c) how participation in a learning program helps to maintain their well-being and independent living despite their daily challenges. Research Design and Methods: This study employed a hermeneutic phenomenological approach. As part of a larger study, we conducted semi-structured interviews with older learners enrolled in general interest courses at a public continuing education program...
April 26, 2017: Gerontologist
https://www.readbyqxmd.com/read/28449034/parental-break-ups-and-stress-roles-of-age-family-structure-in-44-509-pre-adolescent-children
#8
Agnete S Dissing, Nadya Dich, Anne-Marie Nybo Andersen, Rikke Lund, Naja H Rod
Parental break-up is wide spread, and the effects of parental break-up on children's well-being are known. The evidence regarding child age at break-up and subsequent family arrangements is inconclusive. Aim: to estimate the effects of parental break-up on stress in pre-adolescent children with a specific focus on age at break-up and post-breakup family arrangements. We used data from the Danish National Birth Cohort. Participants included 44 509 children followed from birth to age 11. Stress was self-reported by children at age 11, when the children also reported on parental break-up and post break-up family arrangements...
April 25, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28448804/the-associations-between-childhood-trauma-neuroticism-and-comorbid-obsessive-compulsive-symptoms-in-patients-with-psychotic-disorders
#9
Marieke Josien Schreuder, Frederike Schirmbeck, Carin Meijer, Lieuwe de Haan
Various studies reported remarkably high prevalence rates of obsessive-compulsive symptoms (OCS) in patients with a psychotic disorder. Little is known about the pathogenesis of this co-occurrence. The current study aimed to investigate the contribution of shared underlying risk factors, such as childhood trauma and neuroticism, to the onset and course of OCS in patients with psychosis. Data were retrieved from 161 patients with psychosis included in the 'Genetic Risk and Outcome in Psychosis' project. Patients completed measures of OCS and psychotic symptoms at study entrance and three years later...
April 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28448659/evaluation-of-ecological-momentary-assessment-for-tinnitus-severity
#10
Rachel L Goldberg, Marilyn L Piccirillo, Joyce Nicklaus, Andrew Skillington, Eric Lenze, Thomas L Rodebaugh, Dorina Kallogjeri, Jay F Piccirillo
Importance: Existing patient-reported outcome measures of tinnitus assess the severity and disability retrospectively, which may result in adequate reliability, but cannot capture the fluctuating and individualized nature of tinnitus. Experience sampling may provide an alternative. Objective: To use an ecological momentary assessment (EMA) to measure tinnitus disability and associated constructs. Design, Setting, and Participants: Forty adults with tinnitus provided self-report of their tinnitus bother using 5 questions measured by EMA, as well as standard retrospective outcome measures...
April 27, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28448526/human-alkaline-phosphatase-dephosphorylates-microbial-products-and-is-elevated-in-preterm-neonates-with-a-history-of-late-onset-sepsis
#11
Matthew Pettengill, Juan D Matute, Megan Tresenriter, Julie Hibbert, David Burgner, Peter Richmond, José Luis Millán, Al Ozonoff, Tobias Strunk, Andrew Currie, Ofer Levy
BACKGROUND: A host defense function for Alkaline phosphatases (ALPs) is suggested by the contribution of intestinal ALP to detoxifying bacterial lipopolysaccharide (endotoxin) in animal models in vivo and the elevation of ALP activity following treatment of human cells with inflammatory stimuli in vitro. However the activity of ALP in human plasma (primarily tissue-nonspecific ALP; TNAP) on lipopolysaccharide and other microbial products has not been assessed, nor has its expression been studied in preterm newborns, a vulnerable population at high risk of sepsis...
2017: PloS One
https://www.readbyqxmd.com/read/28448489/determinants-of-severe-dehydration-from-diarrheal-disease-at-hospital-presentation-evidence-from-22-years-of-admissions-in-bangladesh
#12
Jason R Andrews, Daniel T Leung, Shahnawaz Ahmed, Mohammed Abdul Malek, Dilruba Ahmed, Yasmin Begum, Firdausi Qadri, Tahmeed Ahmed, Abu Syed Golam Faruque, Eric J Nelson
BACKGROUND: To take advantage of emerging opportunities to reduce morbidity and mortality from diarrheal disease, we need to better understand the determinants of life-threatening severe dehydration (SD) in resource-poor settings. METHODOLOGY/FINDINGS: We analyzed records of patients admitted with acute diarrheal disease over twenty-two years at the International Centre for Diarrhoeal Disease Research, Bangladesh (1993-2014). Patients presenting with and without SD were compared by multivariable logistic regression models, which included socio-demographic factors and pathogens isolated...
April 27, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28448425/vulnerability-to-psychopathology-and-dimensions-of-personality-in-patients-with-fibromyalgia
#13
Alba Garcia-Fontanals, Mariona Portell, Susanna García-Blanco, Violant Poca-Dias, Ferran García-Fructuoso, Marina López-Ruiz, Teresa Gutiérrez-Rosado, Montserrat Gomà-I-Freixanet, Joan Deus
OBJECTIVE: Fibromyalgia (FM) patients may present psychopathology and some characteristic personality traits that may affect their adaptation to the disease. This paper aims to study the relationship between personality dimensions according to the psychobiological model of Cloninger and the presence of psychopathology. METHOD: The study sample consisted of 42 patients with FM and 38 healthy controls. The assessment instruments administered were the Temperament and Character Inventory (TCI-R) and the Millon Clinical Multiaxial Inventory (MCMI-III)...
April 26, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28448249/relationships-among-exercise-beliefs-physical-exercise-and-subjective-wellbeing-evidence-from-korean-middle-aged-adults
#14
Sukkyung You, Kyulee Shin
Physically active leisure plays a key role in successful ageing. Exercise beliefs are one of the key predictors of exercise behavior. We used structural equation modeling to assess the plausibility of a conceptual model specifying hypothesized linkages among middle aged adults perceptions of (a) exercise beliefs, (b) physical exercise behavior, and (c) subjective well-being. Four hundred and two adults in South Korea responded to survey questions designed to capture the above constructs. We found that physically active leisure participation leads to subjective well-being for both middle aged males and females...
April 27, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28447838/in-defense-of-commitment-the-curative-power-of-violated-expectations
#15
Sandra L Murray, Veronica M Lamarche, Sarah Gomillion, Mark D Seery, Cheryl Kondrak
A new model of commitment defense in romantic relationships is proposed. It assumes that relationships afford a central resource for affirming meaning and purpose in the world. Consequently, violating expectations about the world outside the relationship can precipitate commitment defense inside the relationship. A meta-analysis of 5 experiments, 2 follow-up correlational studies, and a longitudinal study of the transition to first parenthood supported the model. Experimentally violating conventional expectations about the world (e...
April 27, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28447806/blame-coping-and-psychosocial-outcomes-in-caregivers-of-individuals-with-brain-injury
#16
Samantha DeDios-Stern, Eun-Jeong Lee
OBJECTIVE: Acquired brain injury (ABI) is associated with many physical and psychiatric conditions. Oftentimes, the individual's family members are responsible for providing long-term care, leaving caregivers vulnerable to negative effects of caregiving including stress, depression, and decreased quality of life. Attribution theory suggests that caregivers may blame the individual with the ABI for their injury as a way to understand their own circumstances. The objective of this study was to investigate caregiver coping strategies as possible mediators between caregiver family member blame and caregiver psychosocial outcomes among caregivers of individuals with ABI...
April 27, 2017: Rehabilitation Psychology
https://www.readbyqxmd.com/read/28447635/a-chromosome-conformation-capture-ordered-sequence-of-the-barley-genome
#17
Martin Mascher, Heidrun Gundlach, Axel Himmelbach, Sebastian Beier, Sven O Twardziok, Thomas Wicker, Volodymyr Radchuk, Christoph Dockter, Pete E Hedley, Joanne Russell, Micha Bayer, Luke Ramsay, Hui Liu, Georg Haberer, Xiao-Qi Zhang, Qisen Zhang, Roberto A Barrero, Lin Li, Stefan Taudien, Marco Groth, Marius Felder, Alex Hastie, Hana Šimková, Helena Staňková, Jan Vrána, Saki Chan, María Muñoz-Amatriaín, Rachid Ounit, Steve Wanamaker, Daniel Bolser, Christian Colmsee, Thomas Schmutzer, Lala Aliyeva-Schnorr, Stefano Grasso, Jaakko Tanskanen, Anna Chailyan, Dharanya Sampath, Darren Heavens, Leah Clissold, Sujie Cao, Brett Chapman, Fei Dai, Yong Han, Hua Li, Xuan Li, Chongyun Lin, John K McCooke, Cong Tan, Penghao Wang, Songbo Wang, Shuya Yin, Gaofeng Zhou, Jesse A Poland, Matthew I Bellgard, Ljudmilla Borisjuk, Andreas Houben, Jaroslav Doležel, Sarah Ayling, Stefano Lonardi, Paul Kersey, Peter Langridge, Gary J Muehlbauer, Matthew D Clark, Mario Caccamo, Alan H Schulman, Klaus F X Mayer, Matthias Platzer, Timothy J Close, Uwe Scholz, Mats Hansson, Guoping Zhang, Ilka Braumann, Manuel Spannagl, Chengdao Li, Robbie Waugh, Nils Stein
Cereal grasses of the Triticeae tribe have been the major food source in temperate regions since the dawn of agriculture. Their large genomes are characterized by a high content of repetitive elements and large pericentromeric regions that are virtually devoid of meiotic recombination. Here we present a high-quality reference genome assembly for barley (Hordeum vulgare L.). We use chromosome conformation capture mapping to derive the linear order of sequences across the pericentromeric space and to investigate the spatial organization of chromatin in the nucleus at megabase resolution...
April 26, 2017: Nature
https://www.readbyqxmd.com/read/28447486/guidance-to-develop-individual-dose-recommendations-for-patients-on-chronic-hemodialysis
#18
Verena Gotta, Kim Dao, Frédérique Rodieux, Thierry Buclin, Françoise Livio, Marc Pfister
In addition to tailored clinical trials in patients on chronic hemodialysis (HD) during drug development, clinician-initiated post-marketing studies and case reports on individual pharmacokinetic (PK) assessments provide an important source of information about drug dialysability and individualized dose recommendations in this vulnerable population. Areas covered: First, factors that may alter drug exposure in HD patients are explained. Second, available regulatory and methodological guidelines for PK assessments in this population are summarized...
April 27, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/28447472/four-year-reciprocal-relationships-between-personality-and-functional-ability-in-older-adults-with-and-without-sensory-impairment-focus-on-neuroticism-and-agreeableness
#19
Markus Wettstein, Hans-Werner Wahl, Vera Heyl
OBJECTIVES: Personality traits have been found to influence health and functional ability (FA) via multiple pathways. However, personality traits may also change in reaction to constraints in FA, particularly in more vulnerable individuals with high risk of decline in independent functioning in daily life (e.g. older adults with sensory impairment). Therefore, conceptually anchored in the World Health Organization's International Classification of Functioning, Disability and Health (ICF model), this study investigated reciprocal relationships between personality, focusing on neuroticism and agreeableness, and indicators of FA (i...
April 27, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28447370/vulnerability-to-forest-loss-through-altered-postfire-recovery-dynamics-in-a-warming-climate-in-the-klamath-mountains
#20
Alan J Tepley, Jonathan R Thompson, Howard E Epstein, Kristina J Anderson-Teixeira
In the context of ongoing climatic warming, certain landscapes could be near a tipping point where relatively small changes to their fire regimes or their postfire forest recovery dynamics could bring about extensive forest loss, with associated effects on biodiversity and carbon-cycle feedbacks to climate change. Such concerns are particularly valid in the Klamath Region of northern California and southwestern Oregon, where severe fire initially converts montane conifer forests to systems dominated by broadleaf trees and shrubs...
April 27, 2017: Global Change Biology
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