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https://www.readbyqxmd.com/read/28231633/barriers-to-regaining-control-within-a-constructivist-grounded-theory-of-family-resilience-in-icu-living-with-uncertainty
#1
Pauline Wong, Pranee Liamputtong, Susan Koch, Helen Rawson
This paper discusses families' experiences of their interactions when a relative is admitted unexpectedly to an Australian intensive care unit BACKGROUND: The overwhelming emotions associated with the unexpected admission of a relative to an intensive care unit (ICU) are often due to the uncertainty surrounding the condition of their critically ill relative. There is limited in-depth understanding of the nature of uncertainty experienced by families in ICU, and interventions perceived by families to minimise their uncertainty are not well documented...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231421/varying-demographic-impacts-of-different-fisheries-on-three-mediterranean-seabird-species
#2
M Genovart, D Doak, J M Igual, S Sponza, J Kralj, D Oro
Fisheries have an enormous economic importance but reconciling their socio-economic features with the conservation and sustainability of marine ecosystems presents major challenges. Bycatch mortality from fisheries is clearly among the most serious global threats for marine ecosystems, affecting a wide range of top predators. Recent estimates report ca. 200,000 seabirds killed annually by bycatch in European waters. However there is an urgent need to rigorously estimate actual mortality rates and quantify effects of bycatch on populations...
February 23, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28231285/the-mother-s-autonomy-in-decision-making-madm-scale-patient-led-development-and-psychometric-testing-of-a-new-instrument-to-evaluate-experience-of-maternity-care
#3
Saraswathi Vedam, Kathrin Stoll, Kelsey Martin, Nicholas Rubashkin, Sarah Partridge, Dana Thordarson, Ganga Jolicoeur
OBJECTIVE: To develop and validate a new instrument that assesses women's autonomy and role in decision making during maternity care. DESIGN: Through a community-based participatory research process, service users designed, content validated, and administered a cross-sectional quantitative survey, including 31 items on the experience of decision-making. SETTING AND PARTICIPANTS: Pregnancy experiences (n = 2514) were reported by 1672 women who saw a single type of primary maternity care provider in British Columbia...
2017: PloS One
https://www.readbyqxmd.com/read/28231256/advancing-the-match-mismatch-framework-for-large-herbivores-in-the-arctic-evaluating-the-evidence-for-a-trophic-mismatch-in-caribou
#4
David Gustine, Perry Barboza, Layne Adams, Brad Griffith, Raymond Cameron, Kenneth Whitten
Climate-induced shifts in plant phenology may adversely affect animals that cannot or do not shift the timing of their reproductive cycle. The realized effect of potential trophic "mismatches" between a consumer and its food varies with the degree to which species rely on dietary income and stored capital. Large Arctic herbivores rely heavily on maternal capital to reproduce and give birth near the onset of the growing season but are they vulnerable to trophic mismatch? We evaluated the long-term changes in the temperatures and characteristics of the growing seasons (1970-2013), and compared growing conditions and dynamics of forage quality for caribou at peak parturition, peak lactation, and peak forage biomass, and plant senescence between two distinct time periods over 36 years (1977 and 2011-13)...
2017: PloS One
https://www.readbyqxmd.com/read/28231060/improving-quality-in-the-preanalytical-phase-through-innovation-on-behalf-of-the-european-federation-for-clinical-chemistry-and-laboratory-medicine-eflm-working-group-for-preanalytical-phase-wg-pre
#5
Giuseppe Lippi, Geoffrey S Baird, Giuseppe Banfi, Karin Bölenius, Janne Cadamuro, Stephen Church, Michael P Cornes, Anna Dacey, Antoine Guillon, Georg Hoffmann, Mads Nybo, Lakdasa Devananda Premawardhana, María Salinas, Sverre Sandberg, Robbert Slingerland, Ana Stankovic, Sylte Marit Sverresdotter, Pieter Vermeersch, Ana-Maria Simundic
It is now undeniable that laboratory testing is vital for the diagnosis, prognostication and therapeutic monitoring of human disease. Despite the many advances made for achieving a high degree of quality and safety in the analytical part of diagnostic testing, many hurdles in the total testing process remain, especially in the preanalytical phase ranging from test ordering to obtaining and managing the biological specimens. The Working Group for the Preanalytical Phase (WG-PRE) of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) has planned many activities aimed at mitigating the vulnerability of the preanalytical phase, including the organization of three European meetings in the past 7 years...
February 23, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28230810/the-vulnerability-of-people-to-landslides-a-case-study-on-the-relationship-between-the-casualties-and-volume-of-landslides-in-china
#6
Qigen Lin, Ying Wang, Tianxue Liu, Yingqi Zhu, Qi Sui
The lack of a detailed landslide inventory makes research on the vulnerability of people to landslides highly limited. In this paper, the authors collect information on the landslides that have caused casualties in China, and established the Landslides Casualties Inventory of China. 100 landslide cases from 2003 to 2012 were utilized to develop an empirical relationship between the volume of a landslide event and the casualties caused by the occurrence of the event. The error bars were used to describe the uncertainty of casualties resulting from landslides and to establish a threshold curve of casualties caused by landslides in China...
February 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28230796/a-sensor-data-fusion-system-based-on-k-nearest-neighbor-pattern-classification-for-structural-health-monitoring-applications
#7
Jaime Vitola, Francesc Pozo, Diego A Tibaduiza, Maribel Anaya
Civil and military structures are susceptible and vulnerable to damage due to the environmental and operational conditions. Therefore, the implementation of technology to provide robust solutions in damage identification (by using signals acquired directly from the structure) is a requirement to reduce operational and maintenance costs. In this sense, the use of sensors permanently attached to the structures has demonstrated a great versatility and benefit since the inspection system can be automated. This automation is carried out with signal processing tasks with the aim of a pattern recognition analysis...
February 21, 2017: Sensors
https://www.readbyqxmd.com/read/28230781/-dose-to-mother-deuterium-oxide-dilution-technique-an-accurate-strategy-to-measure-vitamin-a-intake-in-breastfed-infants
#8
Veronica Lopez-Teros, Ana Teresa Limon-Miro, Humberto Astiazaran-Garcia, Sherry A Tanumihardjo, Orlando Tortoledo-Ortiz, Mauro E Valencia
In Mexico, infants (0-2 years old) show the highest prevalence of vitamin A deficiency (VAD), measured by serum retinol concentrations. Thus, we consider that low vitamin A (VA) intake through breast milk (BM) combined with poor weaning practices are the main factors that contribute to VAD in this group. We combined the assessment of VA status in lactating women using BM retinol and a stable isotope 'dose-to-mother' technique to measure BM production in women from urban and agricultural areas. Infants' mean BM intake was 758 ± 185 mL, and no difference was observed between both areas (p = 0...
February 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28230748/an-increase-in-consuming-adequately-iodized-salt-may-not-be-enough-to-rectify-iodine-deficiency-in-pregnancy-in-an-iodine-sufficient-area-of-china
#9
Zhifang Wang, Wenming Zhu, Zhe Mo, Yuanyang Wang, Guangming Mao, Xiaofeng Wang, Xiaoming Lou
Universal salt iodization (USI) has been implemented for two decades in China. It is crucial to periodically monitor iodine status in the most vulnerable population, such as pregnant women. A cross-sectional study was carried out in an evidence-proved iodine-sufficient province to evaluate iodine intake in pregnancy. According to the WHO/UNICEF/ICCIDD recommendation criteria of adequate iodine intake in pregnancy (150-249 µg/L), the median urinary iodine concentration (UIC) of the total 8159 recruited pregnant women was 147...
February 20, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28230452/prescription-drug-utilization-and-reimbursement-increased-following-state-medicaid-expansion-in-2014
#10
Nirosha Mahendraratnam, Stacie B Dusetzina, Joel F Farley
BACKGROUND: The Affordable Care Act (ACA) expanded health care and medication insurance coverage through Medicaid expansion in select states. Expansion has the potential to increase the availability of health services to patients, including prescription medications. However, limited studies have examined how expansion affected prescription drug utilization and reimbursement. OBJECTIVE: To compare prescription drug utilization (number of prescriptions filled) and reimbursement trends between states that did and did not expand Medicaid coverage in 2014, while accounting for known effects of expansion on Medicaid enrollment...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230434/practice-education-facilitator-roles-and-their-value-to-nhs-organisations
#11
Betsy Scott, Terri Rapson, Liz Allibone, Rozi Hamilton, Constance S Mambanje, Laura Pisaneschi
The role of the practice education facilitator (PEF) was introduced to support the management of large student nurse numbers in clinical areas and to monitor and enhance the quality of placements. While much has been written about the activities and roles undertaken by PEFs, less is known about the value of this type of role to the NHS organisations that employ them. This article explores some of the views of PEFs working in a variety of trusts and organisations in London and surrounding counties. There is no consistent job definition and often insufficient support, leading to some PEFs feeling overwhelmed by the work and isolated within the role...
February 23, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28230257/a-general-framework-for-the-assessment-of-power-system-vulnerability-to-malicious-attacks
#12
R Piccinelli, G Sansavini, R Lucchetti, E Zio
The protection and safe operations of power systems heavily rely on the identification of the causes of damage and service disruption. This article presents a general framework for the assessment of power system vulnerability to malicious attacks. The concept of susceptibility to an attack is employed to quantitatively evaluate the degree of exposure of the system and its components to intentional offensive actions. A scenario with two agents having opposing objectives is proposed, i.e., a defender having multiple alternatives of protection strategies for system elements, and an attacker having multiple alternatives of attack strategies against different combinations of system elements...
February 23, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28230097/evidence-for-risk-extrapolation-in-decision-making-by-tadpoles
#13
Adam L Crane, Maud C O Ferrari
Through time, the activity patterns, morphology, and development of both predators and prey change, which in turn alter the relative vulnerability of prey to their coexisting predators. Recognizing these changes can thus allow prey to make optimal decisions by projecting risk trends into the future. We used tadpoles (Lithobates sylvaticus) to test the hypothesis that tadpoles can extrapolate information about predation risk from past information. We exposed tadpoles to an odour that represented either a temporally consistent risk or an increasing risk...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28230049/broad-scale-lake-expansion-and-flooding-inundates-essential-wood-bison-habitat
#14
Jennifer B Korosi, Joshua R Thienpont, Michael F J Pisaric, Peter deMontigny, Joelle T Perreault, Jamylynn McDonald, Myrna J Simpson, Terry Armstrong, Steven V Kokelj, John P Smol, Jules M Blais
Understanding the interaction between the response of a complex ecosystem to climate change and the protection of vulnerable wildlife species is essential for conservation efforts. In the Northwest Territories (Canada), the recent movement of the Mackenzie wood bison herd (Bison bison athabascae) out of their designated territory has been postulated as a response to the loss of essential habitat following regional lake expansion. We show that the proportion of this landscape occupied by water doubled since 1986 and the timing of lake expansion corresponds to bison movements out of the Mackenzie Bison Sanctuary...
February 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28229935/mice-deficient-in-l-12-15-lipoxygenase-show-increased-vulnerability-to-3-nitropropionic-acid-neurotoxicity
#15
Yan He, Rita C Akumuo, Yuan Yang, Sandra J Hewett
Considerable evidence supports a contributory role for leukocyte-type 12/15 Lipoxygenase (L-12/15 LO) in mediating hippocampal and cortical neuronal injury in models of Alzheimer's disease and stroke. Whether L-12/15 LO contributes to neuronal injury in a model of Huntington's disease (HD) has yet to be determined. HD is characterized by marked striatal neuronal loss, which can be mimicked in humans and animals by inhibition of mitochondrial complex II using 3-Nitropropionic acid (3-NP). Herein, we compared histological and behavioral outcomes between mice that were wild-type or null for L-12/15 LO following systemic injection of 3NP...
February 13, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28229226/pericoronary-adipose-tissue-ratio-is-a-stronger-associated-factor-of-plaque-vulnerability-than-epicardial-adipose-tissue-on-coronary-computed-tomography-angiography
#16
Ryo Okubo, Rine Nakanishi, Mikihito Toda, Daiga Saito, Ippei Watanabe, Takayuki Yabe, Hideo Amano, Tatsushi Hirai, Takanori Ikeda
This study was designed to clarify the influence of pericoronary adipose tissue (PAT) on plaque vulnerability using coronary computed tomography angiography (CCTA). A total of 103 consecutive patients who underwent CCTA and subsequent percutaneous coronary intervention (PCI) using intravascular ultrasound (IVUS) for coronary artery disease were enrolled. The PAT ratio was calculated as the sum of the perpendicular thickness of the visceral layer between the coronary artery and the pericardium, or the coronary artery and the surface of the heart at the PCI site, divided by the PAT thickness without a plaque in the same vessel...
February 22, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28229161/high-levels-of-latent-antithrombin-in-plasma-from-patients-with-antithrombin-deficiency
#17
María de la Morena-Barrio, Edna Sandoval, Pilar Llamas, Ewa Wypasek, Mara Toderici, José Navarro-Fernández, Agustín Rodríguez-Alen, Nuria Revilla, Raquel López-Gálvez, Antonia Miñano, José Padilla, Belén de la Morena-Barrio, Jorge Cuesta, Javier Corral, Vincente Vincente
Antithrombin is an anticoagulant serpin that efficiently inhibits multiple procoagulant proteases. The cost for the structural flexibility required for this function is the vulnerability to mutations that impact its folding pathway. Most conformational mutations identified in serpins cause polymerisation. Only three mutations in SERPINC1 affecting two residues have been found to favour transformation to the latent conformation of antithrombin, another hyperstable non-anticoagulant form with strong antiangiogenic activity that constitutes 3 % of plasma antithrombin in healthy subjects...
February 23, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28229113/social-stress-models-in-rodents-towards-enhanced-validity
#18
REVIEW
J M Koolhaas, S F de Boer, B Buwalda, P Meerlo
Understanding the role of the social environment in the development of stress related diseases requires a more fundamental understanding of stress. Stress includes not only the stimulus and the response but also the individual appraisal of the situation. The social environment is not only essential for survival it is at the same time an important source of stressors. This review discusses the social stress concept, how it has been studied in rodents in the course of time and some more recent insights into the appraisal process...
February 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28229107/translational-relevance-of-rodent-models-of-hypothalamic-pituitary-adrenal-function-and-stressors-in-adolescence
#19
REVIEW
Cheryl M McCormick, Matthew R Green, Jonathan J Simone
Elevations in glucocorticoids that result from environmental stressors can have programming effects on brain structure and function when the exposure occurs during sensitive periods that involve heightened neural development. In recent years, adolescence has gained increasing attention as another sensitive period of development, a period in which pubertal transitions may increase the vulnerability to stressors. There are similarities in physical and behavioural development between humans and rats, and rats have been used effectively as an animal model of adolescence and the unique plasticity of this period of ontogeny...
February 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28229105/early-life-adversity-lasting-consequences-for-emotional-learning
#20
REVIEW
Harm J Krugers, J Marit Arp, Hui Xiong, Sofia Kanatsou, Sylvie L Lesuis, Aniko Korosi, Marian Joels, Paul J Lucassen
The early postnatal period is a highly sensitive time period for the developing brain, both in humans and rodents. During this time window, exposure to adverse experiences can lastingly impact cognitive and emotional development. In this review, we briefly discuss human and rodent studies investigating how exposure to adverse early life conditions - mainly related to quality of parental care - affects brain activity, brain structure, cognition and emotional responses later in life. We discuss the evidence that early life adversity hampers later hippocampal and prefrontal cortex functions, while increasing amygdala activity, and the sensitivity to stressors and emotional behavior later in life...
February 2017: Neurobiology of Stress
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