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https://www.readbyqxmd.com/read/28231566/one-year-outcomes-of-1-pro-re-nata-versus-3-pro-re-nata-intravitreal-aflibercept-injection-for-neovascular-age-related-macular-degeneration
#1
Kei Takayama, Hiroki Kaneko, Tadasu Sugita, Ruka Maruko, Kyoko Hattori, Eimei Ra, Kenichi Kawano, Keiko Kataoka, Yasuki Ito, Hiroko Terasaki
PURPOSE: We compared 1-year outcomes of 1 + pro re nata (PRN) versus 3 + PRN of intravitreal aflibercept injection (IAI) for age-related macular degeneration (AMD). METHODS: Forty-two eyes with naïve AMD received 3 + PRN IAI treatment and 47 eyes with naïve AMD received 1 + PRN IAI treatment. Visual acuity (VA), central retinal thickness (CRT), and central choroidal thickness (CCT) and number of administered IAIs during 12 months were compared. RESULTS: VAs improved, and CRTs reduced significantly at any given month from baseline in both groups (p < 0...
February 24, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28226944/3d-force-torque-characterization-of-emergency-cricothyroidotomy-procedure-using-an-instrumented-scalpel
#2
Adam Ryason, Ganesh Sankaranarayanan, Kathryn L Butler, Marc DeMoya, Suvranu De, Adam Ryason, Ganesh Sankaranarayanan, Kathryn L Butler, Marc DeMoya, Suvranu De, Suvranu De, Marc DeMoya, Kathryn L Butler, Ganesh Sankaranarayanan, Adam Ryason
Emergency Cricothyroidotomy (CCT) is a surgical procedure performed to secure a patient's airway. This high-stakes, but seldom-performed procedure is an ideal candidate for a virtual reality simulator to enhance physician training. For the first time, this study characterizes the force/torque characteristics of the cricothyroidotomy procedure, to guide development of a virtual reality CCT simulator for use in medical training. We analyze the upper force and torque thresholds experienced at the human-scalpel interface...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28221029/highly-efficient-and-thermally-stable-k3alf6-mn4-as-a-red-phosphor-for-ultra-high-performance-warm-white-leds
#3
Enhai Song, Jianqing Wang, Jiahao Shi, Tingting Deng, Shi Ye, Mingying Peng, Jing Wang, Lothar Wondraczek, Qinyuan Zhang
Following pioneering work, solution-processable Mn4+-activated fluoride pigments, such as A2BF6 (A = Na, K, Rb, Cs; A2 = Ba, Zn; B = Si, Ge, Ti, Zr, Sn), have attracted considerable attention as highly promising red phosphors for warm white light emitting diodes (W-LEDs). To date, these fluoride pigments have been synthesized via traditional chemical routes with HF-solution. However, in addition to the possible dangers of hypertoxic HF, the uncontrolled precipitation of fluorides and the extensive processing steps produce large morphological variations, resulting in a wide variation in the LED performance of the resulting devices, which hampers their prospects for practical applications...
February 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28220849/the-long-term-anterior-segment-configuration-after-pediatric-cataract-surgery-and-the-association-with-secondary-glaucoma
#4
Ding Chen, Xian-Hui Gong, He Xie, Xue-Ning Zhu, Jin Li, Yun-E Zhao
Secondary glaucoma constitutes major sight-threatening complication of pediatric cataract surgery, yet the etiology remains unclear. The purpose of this study was to investigate the long-term anterior segment configuration and the association with secondary glaucoma in pediatric pseudophakia. Ultrasound biomicroscopy (UBM) was performed on 40 eyes of 26 children underwent pediatric cataract surgery and intraocular lens (IOL) implantation. The anterior chamber depth (ACD), angle-opening distance at 500 μm (AOD500), trabecular-iris angle (TIA), central corneal thickness (CCT), structural abnormities, IOL position, IOP, and incidence of glaucoma were evaluated...
February 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28211181/a-national-survey-of-the-use-of-pachymeters-by-optometrists-in-scotland-experience-views-and-barriers-to-use
#5
Colin Goudie, Savva Pronin, Helen Court, Janet Pooley, Andrew J Tatham
PURPOSE: Thin central corneal thickness (CCT) is a risk factor for glaucoma. In 2016 all optometry practices in Scotland were provided with pachymeters aiming to improve risk assessment and accuracy of referrals to secondary care. We examined optometrists' experience and views of pachymetry, including perceived barriers to pachymetry in primary care. METHODS: A questionnaire was sent using the REDCap electronic data capture tool to all 1264 optometrists registered with NHS Education for Scotland (NES)...
March 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28210179/corneal-biomechanics-in-normal-saudi-individuals
#6
Khalid Al-Arfaj, Sanaa A Yassin, Walaa Al-Dairi, Fatimah Al-Shamlan, Mohanna Al-Jindan
PURPOSE: The aim of this study was to determine and relate corneal biomechanical metrics with demographic, tomographic and refractive data in healthy Saudi people. DESIGN: Prospective, cross-sectional, observational study. PARTICIPANTS: The study included 215 normal Saudi adult individuals. METHODS: Corneal hysteresis (CH) and corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg) and corneal-compensated intraocular pressure (IOPcc) were measured by ocular response analyzer...
July 2016: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28207520/characterization-of-ocular-biometrics-and-aqueous-humor-dynamics-in-primary-angle-closure-suspects
#7
Li Guo, Yuan Deng, Li Fang, Chaoqi Liu, Tao Guo
Detailed characterizations of ocular biometrics and parameters of aqueous humor dynamics are lacking in primary angle closure suspect (PACS) patients. This study aims to characterize these parameters and compare them with age-matched healthy volunteers.Elderly healthy volunteers (60.6 ± 7.2 years of age, mean ± SD, n = 28) and PACS patients (64.1 ± 11.6 years, n = 30) completed the study. Parameters investigated were axial length (AXL), anterior chamber depth (ACD), anterior chamber volume (ACV), central cornea thickness (CCT), intraocular pressure (IOP), aqueous flow (Fa), outflow facility (C), episcleral venous pressure (EVP), and uveoscleral outflow (Fu)...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28206707/probing-the-interactions-of-cytotoxic-pt-1s-2s-dach-5-6-dimethyl-1-10-phenanthroline-and-its-pt-iv-derivatives-with-human-serum
#8
Dan Gibson, Benjamin Harper, Aviva Friedman-Ezra, Roman Sirota, Emanuele Emanuele Petruzzella, Janice R Aldrich-Wright
The discrepancy between the in vitro cytotoxic results and the in vivo performance of Pt56MeSS, prompted us to look into its interactions and those of its Pt(IV) derivatives with human serum, HSA, lipoproteins and serum supplemented cell culture medium. The Pt(II) complex, Pt56MeSS, binds non-covalently and reversibly to slow tumbling proteins in human serum and in cell culture medium and interacts through the phenanthroline with HSA with a Kd of about 1.5 × 10-6. All Pt(IV) complexes were stable to reduction in HS but those with axial carboxylate ligands, cct-[Pt(1S,2S-DACH)(5,6-dimethyl-1,10-phenantroline)(acetato)2](TFA)2 (Pt56MeSS(OAc)2) and cct-[Pt(1S,2S-DACH)(5,6-dimehtyl-1,10-phenantroline)(phenylbutyrate)2](TFA)2 (Pt56MeSS(PhB)2), were spontaneously reduced at pH=7 or higher in phosphate buffer, but not in tris buffer (pH=8)...
February 16, 2017: ChemMedChem
https://www.readbyqxmd.com/read/28202247/radiological-characteristics-of-atrial-myxoma-in-cardiac-computed-tomography
#9
Kawa Haji, Arthur Nasis
BACKGROUND: Although the primary role of Cardiac Computed Tomography (CCT) is assessment of the coronary arteries, the technique also allows detailed examination of cardiac structures and other cardiac pathologies including cardiac myxoma. However, limited data exists regarding the CCT characteristics of cardiac myxoma. OBJECTIVE: To describe the radiological characteristics of a series of cardiac myxomas in CCT. METHODS: We retrospectively identified all patients at our tertiary urban referral centre with cardiac myxoma on CCT over a seven-year period between July 2008 and July 2015...
February 7, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28182167/comparison-of-intraocular-pressure-measurements-in-healthy-pediatric-patients-using-three-types-of-tonometers
#10
Muhsin Eraslan, Eren Çerman, Sena Sümmen
OBJECTIVES: This study aimed to compare intraocular pressure (IOP) measurements in healthy pediatric patients using three types of tonometers. MATERIALS AND METHODS: Seventy-eight eyes of 78 patients under the age of 18 who underwent a routine ophthalmologic examination were included in the study. IOP was measured using Tono-Pen (TP) tonometry, Goldmann applanation tonometry (GAT), and non-contact tonometry (NCT), consecutively. IOP was adjusted based on central corneal thickness (CCT)...
January 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28177608/thermally-stable-white-emitting-eu-3-complex-nanozeolite-luminescent-glass-composite-with-high-cri-for-organic-resin-free-warm-white-leds
#11
Jinhui Zhang, Shuming Gong, Jinbo Yu, Peng Li, Xuejie Zhang, Yuwei He, Jianbang Zhou, Rui Shi, Huanrong Li, Aiyun Peng, Jing Wang
Nowadays, it is still a great challenge for lanthanide complexes to be applied in solid state lighting, especially for high-power LEDs because they will suffer severe thermal-induced luminescence quenching and transmittance loss when LEDs are operated at high current. In this paper, we have not only obtained high efficient and thermally chemical stable red emitting hybrid material by introducing europium complex into nanozeolite (NZ) functionalized with the imidazolium-based stopper but also abated its thermal-induced transmittance loss and luminescence quenching behavior via coating it onto a heat-resistant luminescent glass (LG) with high thermal conductivity (1...
February 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28174762/multidoped-ln-3-gadolinium-dioxycarbonates-as-tunable-white-light-emitting-phosphors
#12
I Nelli, A M Kaczmarek, F Locardi, V Caratto, G A Costa, R Van Deun
Gadolinium dioxycarbonates co-doped with different visible emitting lanthanides were synthesized via a co-precipitation method using oxalic acid as a precipitating agent. Through XRD and DTA/TG investigations, the type-II hexagonal phase of the lanthanide dioxycarbonates was confirmed for all of the samples. The materials constitute of big agglomerates formed by submicrometrical particles. By varying the Ln(3+) doping percentages and ratios and by changing the excitation wavelength the gadolinium dioxycarbonates activated with Sm(3+), Eu(3+), Tb(3+), Dy(3+) and Tm(3+) showed tunable emission colors...
February 8, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28167745/standardisation-of-delivery-and-assessment-of-research-training-for-specialty-trainees-based-on-curriculum-requirements-recommendations-based-on-a-scoping-review
#13
Amar Rangan, James Pitchford, Penny Williams, Brian Wood, Stephen Robson
OBJECTIVES: (1) To conduct a scoping review of postgraduate specialty training (ST) curricula for doctors within Health Education England in order to identify common themes and variations in requirements for training and assessment of research competencies. (2) To make recommendations on standardisation of training for clinical research across ST programmes. SETTING: Health Education England North East and National Institute for Health Research Clinical Research Network (CRN)-North East and North Cumbria...
February 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28165607/prevalence-of-eyelid-laxity-and-its-association-with-ophthalmic-findings-and-disease-severity-in-patients-with-keratoconus
#14
Mohammad Naderan, Ali Jahanrad, Mahgol Farjadnia
PURPOSE: To investigate the prevalence of eyelid laxity and quantify eyelid measurements in normal and keratoconic eyes and the correlations of these findings with ophthalmic parameters and disease severity in patients with keratoconus (KC). METHODS: In a prospective case-control study, prevalence of eyelid laxity and eyelid measurements were evaluated in 53 patients with KC and the same number of matched healthy controls. The eyelid measurements were compared between the groups, as well as mean keratometry (K), central and thinnest corneal thickness (CCT and TCT), astigmatism, manifest refraction spherical equivalent (MRSE), best spectacle-corrected visual acuity (BCVA), and severity of KC according to the Keratoconus Severity Score...
February 3, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28163862/comparison-of-central-corneal-thickness-measurements-by-pentacam-and-ultrasound-pachymetry-in-normal-myopic-patients
#15
Sherif Emerah, Ehab ELZakzouk, Mohamed Farag
INTRODUCTION: Precise measurement of corneal thickness is of crucial importance in corneal refractive procedures. The aim of this work is to compare the central corneal thickness measurements using Scheimpflug imaging (Pentacam) and contact US pachymetry in normal myopic patients. METHODS: This retrospective cohort study was conducted on in 144 eyes of 72 normal myopic patients during 6 months. The study location was the Research Institute of Ophthalmology (Giza, Egypt), and Magrabi Eye Hospital (Dubai, United Arab Emirates)...
December 2016: Electronic Physician
https://www.readbyqxmd.com/read/28162194/-analysis-on-corneal-deformation-and-corneal-biomechanical-changes-after-small-incision-lenticule-extraction
#16
Y L Huang, Y Wang, R Dou, S B Jin, L J Liu, H Li, P H Wei
Objective: To investigate biomechanical effects of central corneal thickness (CCT), and to explore the possible safe range for the tissue removal and percentage of tissue ablation (PTA) of small incision lenticule extraction (SMILE). Methods: Clinical observational study. One hundred and eighty-seven cases (365 eyes) undergoing SMILE surgery were enrolled. Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured before and after surgery by the ocular response analyzer (ORA). Linear regression of CH, CRF and CCT, and percentage of tissue ablation were calculated...
January 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28161695/computerized-cognitive-training-and-brain-derived-neurotrophic-factor-during-bed-rest-mechanisms-to-protect-individual-during-acute-stress
#17
Angelina Passaro, Cecilia Soavi, Uros Marusic, Enrico Rejc, Juana M Sanz, Mario L Morieri, Edoardo Dalla Nora, Voyko Kavcic, Marco V Narici, Carlo Reggiani, Gianni Biolo, Giovanni Zuliani, Stefano Lazzer, Rado Pišot
Acute stress, as bed rest, was shown to increase plasma level of the neurotrophin brain-derived neurotrophic factor (BDNF) in older, but not in young adults. This increase might represent a protective mechanism towards acute insults in aging subjects. Since computerized cognitive training (CCT) is known to protect brain, herein we evaluated the effect of CCT during bed rest on BDNF, muscle mass, neuromuscular function and metabolic parameters. The subjects that underwent CCT did not show an increase of BDNF after bed rest, and showed an anti-insular modification pattern in metabolism...
February 3, 2017: Aging
https://www.readbyqxmd.com/read/28160068/descemet-membrane-endothelial-keratoplasty-for-graft-failure-following-penetrating-keratoplasty
#18
Sonja Heinzelmann, Daniel Böhringer, Philipp Eberwein, Thabo Lapp, Thomas Reinhard, Philip Maier
PURPOSE: Descemet membrane endothelial keratoplasty (DMEK) is superior to penetrating keratoplasty (PK) in terms of visual rehabilitation, intraoperative safety and risk of rejection. Therefore, it seems reasonable to perform DMEK in eyes with endothelial failure following PK. We herein report our first clinical results. METHODS: Nineteen eyes with endothelial graft failure following PK were treated with DMEK. The majority of these eyes (12) had limited visual potential...
February 3, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28149789/prevalence-of-pseudoexfoliation-syndrome-and-its-association-with-ocular-and-systemic-diseases-in-eskisehir-turkey
#19
Nilgun Yildirim, Erdogan Yasar, Huseyin Gursoy, Ertugrul Colak
AIM: To investigate the prevalence of pseudoexfoliation syndrome (PEX) and its associations with ocular and systemic diseases in a population sample aged over 40y. METHODS: A total of 2356 subjects were randomly chosen for the sample population based on the database of the Turkish Statistical Agency in Eskisehir. Of the invited 2356 subjects, 2017 subjects participated, out of which 2009 were eligible for the study. Systemic diseases, drug use, smoking and body mass index were assessed using questionnaires...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28149787/small-incision-lenticule-extraction-versus-femtosecond-lenticule-extraction-for-myopic-a-systematic-review-and-meta-analysis
#20
Jia-Song Wang, Hua-Tao Xie, Ye Jia, Ming-Chang Zhang
AIM: To examine differences in efficacy, accuracy, safety, aberrations and corneal biomechanical between Small incision lenticule extraction (SMILE) and femtosecond lenticule extraction (FLEx) for myopia. METHODS: Comprehensive studies were conducted on the PubMed, MEDLINE, EMBASE, and Cochrane Controlled Trials Register before 31 July, 2015. Meta-analyses were performed on the primary outcomes [loss of ≥2 lines of corrected distance visual acuity (CDVA), uncorrected distance visual acuity (UDVA) ≥20/20, spherical equivalent (SE) within ±0...
2017: International Journal of Ophthalmology
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