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https://www.readbyqxmd.com/read/28636261/characteristics-of-corneal-biomechanical-responses-detected-by-a-non-contact-scheimpflug-based-tonometer-in-eyes-with-glaucoma
#1
Younhea Jung, Hae-Young L Park, Hee Jung Yang, Chan Kee Park
PURPOSE: To determine the corneal biomechanical properties in eyes with glaucoma using a non-contact Scheimpflug-based tonometer. METHODS: Corneal biomechanical responses were examined using a non-contact Scheimpflug-based tonometer. The tonometer parameters of the normal control group (n = 75) were compared with those of the glaucoma group (n = 136), including an analysis of glaucoma subgroups categorized by visual field loss. RESULTS: After adjusting for potential confounding factors, including the intraocular pressure (IOP), central corneal thickness (CCT), age and axial length, the deformation amplitude was smaller in the glaucoma group (1...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28630766/corneal-endothelial-characteristics-central-corneal-thickness-and-intraocular-pressure-in-a-population-of-chinese-age-related-cataract-patients
#2
Yingmei Li, Zhentao Fu, Jian Liu, Miao Li, Yuguang Zhang, Xinyi Wu
PURPOSE: To describe corneal endothelial characteristics, central corneal thickness, and intraocular pressure in a population of Chinese age-related cataract patients and to determine the effects of age, gender, hypertension, and body mass index (BMI). METHODS: 1551 eyes were examined preoperatively. The parameters measured were endothelial cell density (CD), average cell area (CA), coefficient of variation (CV), cell hexagonality (HEX), central corneal thickness (CCT), intraocular pressure (IOP), and axial length (AL)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28626817/comparison-of-current-tonometry-techniques-in-measurement-of-intraocular-pressure
#3
Behrooz Kouchaki, Hassan Hashemi, Abbasali Yekta, Mehdi Khabazkhoob
PURPOSE: To compare four tonometry techniques: Goldmann applanation tonometer (GAT), Dynamic contour tonometer (DCT), Non-contact tonometer (NCT), and Ocular Response Analyzer (ORA) in the measurement of intraocular pressure (IOP) and the impact of some corneal biomechanical factors on their performance. METHODS: In this cross-sectional study, volunteers with normal ophthalmic examination and no history of eye surgery (except for uncomplicated cataract surgery) or trauma were selected...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28625685/objective-quantification-of-anterior-chamber-inflammation-measuring-cells-and-flare-by-anterior-segment-optical-coherence-tomography
#4
Alessandro Invernizzi, Sylvia Marchi, Raffaella Aldigeri, Valentina Mastrofilippo, Fabiana Viscogliosi, Annamaria Soldani, Chantal Adani, Elena Garoli, Francesco Viola, Luigi Fontana, Peter McCluskey, Luca Cimino
PURPOSE: To assess the ability of swept-source (SS) optical coherence tomography (OCT) of the anterior segment (AS) to measure anterior chamber (AC) inflammation (both flare and cells) objectively. To compare OCT-derived inflammatory indices with standard techniques. DESIGN: Prospective evaluation of a diagnostic test. PARTICIPANTS: Patients diagnosed with anterior uveitis (active or inactive) and controls. METHODS: Participants underwent an AC inflammation evaluation including: clinical cell and flare grading and laser flare photometry (LFP)...
June 16, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28624324/risk-factors-for-rapid-glaucoma-disease-progression
#5
Thomas Chun Wai Chan, Chandra Bala, Anna Siu, Fiona Wan, Andrew White
PURPOSE: To determine the intraocular and systemic risk factor differences between a cohort of rapid glaucoma disease progressors and non-rapid disease progressors. DESIGN: Retrospective case control study Methods SETTING: Five private ophthalmology clinics STUDY POPULATION: 48 rapidly progressing eyes (progression ≥1dB mean deviation (MD)/year) and 486 non-rapidly progressing eyes (progression <1dB MD/year). Patients were eligible if they had a diagnosis of glaucoma from their ophthalmologist and if they had greater than or equal to 5 Humphrey visual fields (24-2) conducted...
June 14, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28623285/structure-of-the-human-tric-cct-subunit-5-associated-with-hereditary-sensory-neuropathy
#6
Jose H Pereira, Ryan P McAndrew, Oksana A Sergeeva, Corie Y Ralston, Jonathan A King, Paul D Adams
The human chaperonin TRiC consists of eight non-identical subunits, and its protein-folding activity is critical for cellular health. Misfolded proteins are associated with many human diseases, such as amyloid diseases, cancer, and neuropathies, making TRiC a potential therapeutic target. A detailed structural understanding of its ATP-dependent folding mechanism and substrate recognition is therefore of great importance. Of particular health-related interest is the mutation Histidine 147 to Arginine (H147R) in human TRiC subunit 5 (CCT5), which has been associated with hereditary sensory neuropathy...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28621945/concentration-driven-selectivity-of-energy-transfer-channels-and-color-tunability-in-ba3la-po4-3-tb-3-sm-3-for-warm-white-leds
#7
Weijie Zhou, Meng Gu, Yiyi Ou, Caihua Zhang, Xuejie Zhang, Lei Zhou, Hongbin Liang
Here, we report the large-scale emission color tunability in Ba3La(PO4)3:Tb(3+), Sm(3+) (BLPO:TS) system based on the detailed discussion on the concentration-driven selectivity of energy transfer (ET) channels from Tb(3+) to Sm(3+). It is induced by the concentration-dependent (5)D3 and (5)D4 emissions of Tb(3+) and the different interaction mechanisms of ET from Tb(3+) to Sm(3+) via (5)D3 and (5)D4 channels. In the diluted Tb(3+) scenario, the red emission of Sm(3+) is efficiently sensitized via the (5)D3 channel, while in the concentrated Tb(3+) case, the contribution of (5)D4 channel is dominant...
June 16, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28620727/investigation-of-trace-element-content-in-the-seeds-pulp-and-peel-of-mashui-oranges-using-microwave-digestion-and-icp-ms-analysis
#8
Lingyun Chen, Mei Shen, Ande Ma, Weili Han
Fresh Mashui orange samples were pretreated with microwave digestion using an HNO3-H2O2 system. The levels of Mg, K, Ca, Fe, Mn, Cu, Zn, As, Cd, and Pb in the seeds, pulp, and peel were then determined using inductively coupled plasma mass spectrometry (ICP-MS) combined with collision cell technology (CCT) and kinetic energy discrimination (KED). The standard curve coefficient of determinations of the ten tested elements were between 0.9995 and 0.9999. The instrument detection limit was between 0.112 ng/L and 3...
June 16, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28616659/isolation-and-functional-characterization-of-a-circadian-regulated-constans-homolog-gbco-from-ginkgo-biloba
#9
Jiaping Yan, Dun Mao, Xiaomeng Liu, Lanlan Wang, Feng Xu, Guiyuan Wang, Weiwei Zhang, Yongling Liao
This is the first report to clone and functionally characterize a flowering time gene GbCO in perennial gymnosperm Ginkgo biloba. GbCO complements the co mutant of Arabidopsis, restoring normal early flowering. CONSTANS (CO) is a central regulator of photoperiod pathway, which channels inputs from light, day length, and circadian clock to promote the floral transition. In order to understand the role of CO in gymnosperm Ginkgo biloba, which has a long juvenile phase (15-20 years), a CO homolog (GbCO) was isolated and characterized from G...
June 14, 2017: Plant Cell Reports
https://www.readbyqxmd.com/read/28615922/influence-of-circulating-endothelin-1-and-asymmetric-dimethylarginine-on-whole-brain-circulation-time-in-multiple-sclerosis
#10
Lucia Monti, Lucia Morbidelli, Lorenzo Bazzani, Alessandro Rossi
Blood-brain barrier (BBB) breakdown, inflammatory and immune cell activation, and chronic cerebral hypoperfusion are features of multiple sclerosis (MS). The aim is to determine the influence of endothelin-1 (ET1) and asymmetric dimethylarginine (ADMA) on cerebral circulation time (CCT) in patients with MS. In all, 64 patients with MS (39 relapsing-remitting [RR]-MS; 25 secondary progressive [SP]-MS subtype) and 37 controls (C) were studied. Cerebral circulation time was obtained by angiography. Plasmatic ET1 and ADMA were measured by enzyme-linked immunosorbent assay...
2017: Biomarker Insights
https://www.readbyqxmd.com/read/28607174/aqueous-humour-dynamics-and-biometrics-in-the-ageing-chinese-eye
#11
Tao Guo, Sruthi Sampathkumar, Shan Fan, Nathan Morris, Fang Wang, Carol B Toris
AIMS: This study evaluates ocular biometrics and aqueous humour dynamics (AHD) in healthy Chinese volunteers to determine how the various ocular parameters interact to maintain physiological intraocular pressure (IOP) at all ages. METHODS: Sixty-nine volunteers enrolled in this cross-sectional study and were categorised into young (20-30 years) and old (≥50 years) groups. Measurements included IOP, ocular biometrics and AHD. Data were analysed using mixed model with random sampling to account for both eyes from the same individual...
June 12, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28604498/is-multiple-sclerosis-associated-with-a-lower-intraocular-pressure
#12
Norah S Lincoff, Andrea Buccilli, Bianca Weinstock-Guttman, Sandra Sieminski, Sirin Gandhi
OBJECTIVE: To determine if multiple sclerosis (MS) is associated with lower intraocular pressure (IOP) compared with individuals without MS. METHODS: Thirty patients with clinically definite MS were identified and a retrospective chart review was conducted. Each patient with MS underwent IOP recording by a single investigator using kinetic applanation tonometry. Measurement of central corneal thickness (CCT) also was obtained. Similarly, 30 study controls were identified and kinetic applanation tonometry and CCT were recorded...
June 9, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28603017/effects-of-diabetes-mellitus-on-biomechanical-properties-of-the-rabbit-cornea
#13
FangJun Bao, ManLi Deng, XiaoBo Zheng, LinNa Li, YiPing Zhao, Si Cao, AYong Yu, QinMei Wang, JinHai Huang, Ahmed Elsheikh
To investigate the effects of diabetes on the biomechanical behavior of cornea in alloxan-induced diabetic rabbits. Diabetes mellitus (DM) was induced in 20 rabbits using alloxan, while another 20 age- and weight-matched non-diabetic rabbits served as controls. Eyes were enucleated after 8 weeks of inducing diabetes and the whole cornea was removed with a 3 mm wide scleral ring and tested under inflation conditions with an internal pressure range of 2.0-30.0 mmHg to determine their stress-strain behavior using an inverse analysis process...
June 8, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28602329/central-corneal-thickness-and-intraocular-pressure-changes-after-congenital-cataract-surgery-with-intraocular-lens-implantation-in%C3%A2-children-younger-than-2%C3%A2-years
#14
Jaspreet Sukhija, Savleen Kaur
PURPOSE: To evaluate the change in central corneal thickness (CCT) and intraocular pressure (IOP) preoperatively to postoperatively in children younger than 2 years of age having surgery with primary intraocular lens (IOL) implantation for congenital cataract. SETTING: Tertiary care institute, Chandigarh, India. DESIGN: Prospective case series. METHODS: Children younger than 2 years old who had phacoaspiration with IOL implantation were studied...
May 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28602196/sequence-specific-recognition-of-hiv-1-dsdna-in-the-large-amount-of-normal-dsdna-based-upon-nicking-enzyme-signal-amplification-and-triplex-dna
#15
Houya Zhu, Manjun Zhang, Li Zou, Ruimin Li, Liansheng Ling
A sensitive fluorescent strategy for sequence specific recognition of HIV dsDNA was established based upon Nicking Enzyme Signal Amplification (NESA) and triplex formation. dsDNA sequence from the site 7960 to site 7991 of the HIV1 dsDNA gene was designed as target dsDNA, which was composed of two complementary strands Oligonucleotide 1 with the sequence of 3'-CTT CCT TAT CTT CTT CTT CCA CCT CTC TCT CT-5' (Oligo-1) and Oligonucleotide 2 with the sequence of 5'-GAA GGA ATA GAA GAA GAA GGT GGA GAG AGA GA-3' (Oligo-2)...
October 1, 2017: Talanta
https://www.readbyqxmd.com/read/28592038/-the-application-of-captopril-challenge-test-in-the-diagnosis-of-primary-aldosteronism
#16
S Chen, Z P Zeng, A L Song, L Zhu, L Lu, A L Tong, C Shi, H Z Li
Objective: To evaluate the value of captopril challenge test (CCT) in the diagnosis of primary aldosteronism (PA). Methods: A total of 674 patients [(45.0±13.7) years, men 341, women 333] admitted to Peking Union Medical College Hospital from 2000 to 2015 were analyzed. Among them, 222 subjects were with essential hypertension (EH), 28 were with pheochromocytoma (PHEO), 246 were with idiopathic hyperaldosteronism (IHA) and 178 were with aldosterone producing adenoma (APA). All patients received CCT. 24 h urine sodium was measured in partial patients...
June 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28586052/a-novel-approach-to-select-differential-pathways-associated-with-hypertrophic-cardiomyopathy-based-on-gene-co%C3%A2-expression-analysis
#17
Xiao-Min Chen, Ming-Jun Feng, Cai-Jie Shen, Bin He, Xian-Feng Du, Yi-Bo Yu, Jing Liu, Hui-Min Chu
The present study was designed to develop a novel method for identifying significant pathways associated with human hypertrophic cardiomyopathy (HCM), based on gene co‑expression analysis. The microarray dataset associated with HCM (E‑GEOD‑36961) was obtained from the European Molecular Biology Laboratory‑European Bioinformatics Institute database. Informative pathways were selected based on the Reactome pathway database and screening treatments. An empirical Bayes method was utilized to construct co‑expression networks for informative pathways, and a weight value was assigned to each pathway...
July 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28578737/effects-of-light-emitting-diode-light-v-fluorescent-light-on-growing-performance-activity-levels-and-well-being-of-non-beak-trimmed-w-36-pullets
#18
K Liu, H Xin, P Settar
More energy-efficient, readily dimmable, long-lasting and more affordable light-emitting diode (LED) lights are increasingly finding applications in poultry production facilities. Despite anecdotal evidence about the benefits of such lighting on bird performance and behavior, concrete research data were lacking. In this study, a commercial poultry-specific LED light (dim-to-blue, controllable correlated color temperature (CCT) from 4500 to 5300 K) and a typical compact fluorescent light (CFL) (soft white, CCT=2700 K) were compared with regards to their effects on growing performance, activity levels, and feather and comb conditions of non-beak-trimmed W-36 pullets during a 14-week rearing period...
June 5, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28573757/circuit-class-therapy-for-improving-mobility-after-stroke
#19
REVIEW
Coralie English, Susan L Hillier, Elizabeth A Lynch
BACKGROUND: Circuit class therapy (CCT) offers a supervised group forum for people after stroke to practise tasks, enabling increased practice time without increasing staffing. This is an update of the original review published in 2010. OBJECTIVES: To examine the effectiveness and safety of CCT on mobility in adults with stroke. SEARCH METHODS: We searched the Cochrane Stroke Group Trials Register (last searched January 2017), CENTRAL (the Cochrane Library, Issue 12, 2016), MEDLINE (1950 to January 2017), Embase (1980 to January 2017), CINAHL (1982 to January 2017), and 14 other electronic databases (to January 2017)...
June 2, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28572042/an-analysis-of-the-operative-experience-of-plastic-surgery-trainees-in-the-united-kingdom-using-elogbook
#20
Lyndsey Highton, Andrew Lamb, Aidan Fitzgerald, Simon Wood, Vivien Lees, Robert Winterton
INTRODUCTION: We performed a comprehensive analysis of the operative experience of UK Plastic Surgery Trainees using the web-based eLogbook. METHODS: An analysis of data recorded prospectively by Plastic Surgery Registrars 2010-2014 in eLogbook. RESULTS: The eLogbook data of 336 Specialty Registrars entered from 2010 to 2014 was analysed. Over the six-year training programme, trainees participated in a mean of 2117 procedures and performed a mean of 1571 procedures with or without supervision...
May 22, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
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