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https://www.readbyqxmd.com/read/28636181/identification-of-biomarkers-for-early-diagnosis-of-acute-myocardial-infarction
#1
Wen-Han Ge, Yong Lin, Sen Li, Xuefeng Zong, Zhong-Chun Ge
Acute myocardial infarction (AMI) is a common disease with serious consequences in mortality and cost. Here we aim to screen the differentially expressed genes (DEGs) as biomarkers for early diagnosis of AMI. The microarray data of AMI was downloaded from Gene Expression Omnibus (GEO), including two independent types of research GSE66360 and GSE62646. The DEGs between control and processed samples were screened out by using limma package. Meanwhile, we performed functional analysis of GO terms and/or KEGG pathways to observe the enriched pathways of the DEGs...
June 21, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28635503/practical-guidelines-to-minimise-language-and-cognitive-confounds-in-the-diagnosis-of-capd-a-brief-tutorial
#2
Gail D Chermak, Doris-Eva Bamiou, Vasiliki Vivian Iliadou, Frank E Musiek
OBJECTIVE: To provide audiologists with strategies to minimise confounding cognitive and language processing variables and accurately diagnose central auditory processing disorder (CAPD). DESIGN: Tutorial. STUDY SAMPLE: None. RESULTS: Strategies are reviewed to minimise confounding cognitive and language processing variables and accurately diagnose CAPD. CONCLUSIONS: Differential diagnosis is exceedingly important and can be quite challenging...
February 28, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28635351/assessing-the-quality-of-bereavement-care-after-perinatal-death-development-and-piloting-of-a-questionnaire-to-assess-parents-experiences
#3
Esther Aiyelaagbe, Rebecca E Scott, Victoria Holmes, Emma Lane, Alexander E P Heazell
Understanding parents' experience of care is essential to develop high-quality perinatal bereavement services. This study aimed at developing a questionnaire to identify parents' needs and record their experience of care. The patient experience questionnaire was developed by professionals and parents, and piloted in a tertiary maternity unit. Responses were received from 58 parents. Sensitivity and kindness of staff and time spent with their baby were ranked as 'very important' by 95% of parents. Care in these areas largely met their needs (90%), although 5% of respondents stated that partners could have been more involved...
June 21, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28634427/leveraging-food-and-drug-administration-adverse-event-reports-for-the-automated-monitoring-of-electronic-health-records-in-a-pediatric-hospital
#4
Huaxiu Tang, Imre Solti, Eric Kirkendall, Haijun Zhai, Todd Lingren, Jaroslaw Meller, Yizhao Ni
The objective of this study was to determine whether the Food and Drug Administration's Adverse Event Reporting System (FAERS) data set could serve as the basis of automated electronic health record (EHR) monitoring for the adverse drug reaction (ADR) subset of adverse drug events. We retrospectively collected EHR entries for 71 909 pediatric inpatient visits at Cincinnati Children's Hospital Medical Center. Natural language processing (NLP) techniques were used to identify positive diseases/disorders and signs/symptoms (DDSSs) from the patients' clinical narratives...
2017: Biomedical Informatics Insights
https://www.readbyqxmd.com/read/28634156/classifying-chinese-questions-related-to-health-care-posted-by-consumers-via-the-internet
#5
Haihong Guo, Xu Na, Li Hou, Jiao Li
BACKGROUND: In question answering (QA) system development, question classification is crucial for identifying information needs and improving the accuracy of returned answers. Although the questions are domain-specific, they are asked by non-professionals, making the question classification task more challenging. OBJECTIVE: This study aimed to classify health care-related questions posted by the general public (Chinese speakers) on the Internet. METHODS: A topic-based classification schema for health-related questions was built by manually annotating randomly selected questions...
June 20, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28634153/beyond-basic-feedback-in-mobile-brief-interventions-designing-sms-message-content-for-delivery-to-young-adults-during-risky-drinking-events
#6
Cassandra J C Wright, Paul M Dietze, Megan S C Lim
BACKGROUND: Brief interventions can reduce alcohol consumption in young people through screening and delivery of personally relevant feedback. Recently, Web and mobile platforms have been harnessed to increase the reach of brief interventions. Existing literature on mobile-based alcohol brief interventions indicates mixed use of theory in developing interventions. There is no research available to guide the development of SMS text messaging (short message service, SMS) interventions delivered during risky drinking events...
June 20, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28634104/natural-language-processing-for-asthma-ascertainment-in-different-practice-settings
#7
Chung-Il Wi, Sunghwan Sohn, Mir Ali, Elizabeth Krusemark, Euijung Ryu, Hongfang Liu, Young J Juhn
BACKGROUND: We developed and validated NLP-PAC, a natural language processing (NLP) algorithm based on predetermined asthma criteria (PAC) for asthma ascertainment using electronic health records at Mayo Clinic. OBJECTIVE: To adapt NLP-PAC in a different health care setting, Sanford Children Hospital, by assessing its external validity. METHODS: The study was designed as a retrospective cohort study that used a random sample of 2011-2012 Sanford Birth cohort (n = 595)...
June 17, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28633887/visual-integration-of-fear-and-anger-emotional-cues-by-children-on-the-autism-spectrum-and-neurotypical-peers-an-eeg-study
#8
Evie Malaia, Debbie Cockerham, Katherine Rublein
Communication deficits in children with autism spectrum disorders (ASD) are often related to inefficient interpretation of emotional cues, which are conveyed visually through both facial expressions and body language (Apicella et al., 2012). The present study examined ASD behavioral and ERP responses to emotional expressions of anger and fear, as conveyed by the face and body. Behavioral results showed significantly faster response times for the ASD than for the typically developing (TD) group when processing fear, but not anger, in isolated face expressions, isolated body expressions, and in the integration of the two...
June 17, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28632303/audition-specific-temporal-processing-deficits-associated-with-language-function-in-children-with-autism-spectrum-disorder
#9
Jennifer H Foss-Feig, Kimberly B Schauder, Alexandra P Key, Mark T Wallace, Wendy L Stone
Sensory processing alterations are highly prevalent in autism spectrum disorder (ASD). Neurobiologically-based theories of ASD propose that abnormalities in the processing of temporal aspects of sensory input could underlie core symptoms of ASD. For example, rapid auditory temporal processing is critical for speech perception, and language difficulties are central to the social communication deficits defining the disorder. This study assessed visual and auditory temporal processing abilities and tested their relation to core ASD symptoms...
June 20, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28631953/a-morpho-phonological-past-tense-processing-as-a-clinical-marker-in-sli-efl-learners
#10
Elena Even-Simkin
The clinical marker in specific language impairment (SLI) population is the subject of considerable debate. SLI is the one of the frequently diagnosed atypical language phenomena found among early school-age children (McArthur et al., 2000; Spear-Swerling, 2006). For example, children with SLI have difficulty applying the Past Tense rule to verbs, even though they can accurately repeat phonologically similar forms of the words (Hoeffner & McClelland, 1993). In this study, I discuss the grammatical deficits in the SLI population by studying the generation of both 'regular' and 'irregular' English Past Tense forms and explain how the rates of the correct use of the 'irregular' versus 'regular' form may be considered as a clinical SLI marker...
February 15, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28631809/anabolic-steroids-for-treating-pressure-ulcers
#11
REVIEW
Cho Naing, Maxine A Whittaker
BACKGROUND: Pressure ulcers, also known as bed sores, pressure sores or decubitus ulcers develop as a result of a localised injury to the skin or underlying tissue, or both. The ulcers usually arise over a bony prominence, and are recognised as a common medical problem affecting people confined to a bed or wheelchair for long periods of time. Anabolic steroids are used as off-label drugs (drugs which are used without regulatory approval) and have been used as adjuvants to usual treatment with dressings, debridement, nutritional supplements, systemic antibiotics and antiseptics, which are considered to be supportive in healing of pressure ulcers...
June 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28631183/comprehension-of-idioms-in-turkish-aphasic-participants
#12
Burcu Aydin, Muzaffer Barin, Oktay Yagiz
Brain damaged participants offer an opportunity to evaluate the cognitive and linguistic processes and make assumptions about how the brain works. Cognitive linguists have been investigating the underlying mechanisms of idiom comprehension to unravel the ongoing debate on hemispheric specialization in figurative language comprehension. The aim of this study is to evaluate and compare the comprehension of idiomatic expressions in left brain damaged (LBD) aphasic, right brain damaged (RBD) and healthy control participants...
June 19, 2017: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/28630655/neural-patterns-elicited-by-sentence-processing-uniquely-characterize-typical-development-sli-recovery-and-sli-persistence
#13
Eileen Haebig, Christine Weber, Laurence B Leonard, Patricia Deevy, J Bruce Tomblin
BACKGROUND: A substantial amount of work has examined language abilities in young children with specific language impairment (SLI); however, our understanding of the developmental trajectory of language impairment is limited. Along with studying the behavioral changes that occur across development, it is important to examine the neural indices of language processing for children with different language trajectories. The current study sought to examine behavioral and neural bases of language processing in adolescents showing three different trajectories: those with normal language development (NL), those exhibiting persistent SLI (SLI-Persistent), and those with a history of SLI who appear to have recovered (SLI-Recovered)...
2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/28630032/what-are-people-tweeting-about-zika-an-exploratory-study-concerning-its-symptoms-treatment-transmission-and-prevention
#14
Michele Miller, Tanvi Banerjee, Roopteja Muppalla, William Romine, Amit Sheth
BACKGROUND: In order to harness what people are tweeting about Zika, there needs to be a computational framework that leverages machine learning techniques to recognize relevant Zika tweets and, further, categorize these into disease-specific categories to address specific societal concerns related to the prevention, transmission, symptoms, and treatment of Zika virus. OBJECTIVE: The purpose of this study was to determine the relevancy of the tweets and what people were tweeting about the 4 disease characteristics of Zika: symptoms, transmission, prevention, and treatment...
June 19, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28629645/atypical-activation-of-action-semantic-network-in-adolescents-with-autism-spectrum-disorder
#15
Tracey A Knaus, Claire Burns, Jodi Kamps, Anne L Foundas
In typical adults, fMRI studies have shown activation of primary and pre-motor regions during action word processing. Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social and communication impairments. ASD studies have shown atypical semantic processing and motor deficits. The objective of this study was to examine semantic processing of verbs in ASD. 15 ASD adolescents and 19 typically developing adolescents, 11-16years, completed a semantic similarity judgment task during fMRI...
June 16, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28628785/looking-at-a-contrast-object-before-speaking-boosts-referential-informativeness-but-is-not-essential
#16
Catherine Davies, Helene Kreysa
Variation in referential form has traditionally been accounted for by theoretical frameworks focusing on linguistic and discourse features. Despite the explosion of interest in eye tracking methods in psycholinguistics, the role of visual scanning behaviour in informative reference production is yet to be comprehensively investigated. Here we examine the relationship between speakers' fixations to relevant referents and the form of the referring expressions they produce. Overall, speakers were fully informative across simple and (to a lesser extent) more complex displays, providing appropriately modified referring expressions to enable their addressee to locate the target object...
June 16, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28627934/adult-patient-decision-making-regarding-implantation-of-complex-cardiac-devices-a-scoping-review
#17
Alison Malecki-Ketchell, Paul Marshall, Joan Maclean
BACKGROUND: Complex cardiac rhythm management device (CRMD) therapy provides an important treatment option for people at risk of sudden cardiac death. Despite the survival benefit, device implantation is associated with significant physical and psychosocial concerns presenting considerable challenges for the decision-making process surrounding CRMD implantation for patients and physicians. AIMS: The purpose of this scoping review was to explore what is known about how adult (>16 years) patients make decisions regarding implantation of CRMD therapy...
June 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28627690/data-mining-and-pathway-analysis-of-glucose-6-phosphate-dehydrogenase-with-natural-language-processing
#18
Long Chen, Chunhua Zhang, Yanling Wang, Yuqian Li, Qiaoqiao Han, Huixin Yang, Yuechun Zhu
Human glucose-6-phosphate dehydrogenase (G6PD) is a crucial enzyme in the pentose phosphate pathway, and serves an important role in biosynthesis and the redox balance. G6PD deficiency is a major cause of neonatal jaundice and acute hemolyticanemia, and recently, G6PD has been associated with diseases including inflammation and cancer. The aim of the present study was to conduct a search of the National Center for Biotechnology Information PubMed library for articles discussing G6PD. Genes that were identified to be associated with G6PD were recorded, and the frequency at which each gene appeared was calculated...
June 15, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28627309/measuring-light-at-night-and-melatonin-levels-in-shift-workers-a-review-of-the-literature
#19
Claudia M Hunter, Mariana G Figueiro
Shift work, especially that involving rotating and night shifts, is associated with an increased risk of diseases, including cancer. Attempts to explain the association between shift work and cancer in particular have focused on the processes of melatonin production and suppression. One hypothesis postulates that exposure to light at night (LAN) suppresses melatonin, whose production is known to slow the development of cancerous cells, while another proposes that circadian disruption associated with shift work, and not just LAN, increases health risks...
July 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28627039/consensus-building-on-developing-dysphagia-competence-a-north-west-of-england-perspective
#20
Susan Guthrie, John Lancaster, Jois Stansfield
BACKGROUND: Dysphagia has been an increasing area of practice for speech and language therapists (SLTs) for over 20 years, and throughout that period there has been debate about how practical skills in dysphagia can best be developed. The implementation of the new Royal College of Speech and Language Therapists (RCSLT) framework was considered from a regional perspective seeking to establish consensus across different speech and language therapy settings. AIM: To explore practical solutions to the development of dysphagia competency in new graduates whilst acknowledging the wide variation in staffing and clinical dysphagia experience across the geographical and clinical landscape in the North West of England...
June 19, 2017: International Journal of Language & Communication Disorders
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