Tezcan Ozrazgat-Baslanti, Yuanfang Ren, Esra Adiyeke, Rubab Islam, Haleh Hashemighouchani, Matthew Ruppert, Shunshun Miao, Tyler Loftus, Crystal Johnson-Mann, R W M A Madushani, Elizabeth A Shenkman, William Hogan, Mark S Segal, Gloria Lipori, Azra Bihorac, Charles Hobson
Standard race adjustments for estimating glomerular filtration rate (GFR) and reference creatinine can yield a lower acute kidney injury (AKI) and chronic kidney disease (CKD) prevalence among African American patients than non-race adjusted estimates. We developed two race-agnostic computable phenotypes that assess kidney health among 139,152 subjects admitted to the University of Florida Health between 1/2012-8/2019 by removing the race modifier from the estimated GFR and estimated creatinine formula used by the race-adjusted algorithm (race-agnostic algorithm 1) and by utilizing 2021 CKD-EPI refit without race formula (race-agnostic algorithm 2) for calculations of the estimated GFR and estimated creatinine...
2024: PloS One