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https://www.readbyqxmd.com/read/28644697/contemporary-treatment-of-renal-tumors-a-questionnaire-survey-in-the-nordic-countries-the-norenca-i-study
#1
Harry Nisen, Petrus Järvinen, Magnus Fovaeus, Eirikur Guðmundsson, Bjarne Kromann-Andersen, Börje Ljungberg, Lars Lund, Frode Nilsen, Pernilla Sundqvist, Christian Beisland
OBJECTIVE: The five Nordic countries comprise 25 million people, and have similar treatment traditions and healthcare systems. To take advantage of these similarities, a collaborative group (Nordic Renal Cancer Group, NORENCA) was founded in 2015. MATERIALS AND METHODS: A questionnaire of 17 questions on renal tumor management and surgical education was designed and sent to 91 institutions performing renal tumor surgery in 2015. The response rate was 68% (62 hospitals), including 28 academic, 25 central and nine district hospitals...
June 23, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28625045/size-dependent-heating-of-magnetic-iron-oxide-nanoparticles
#2
Sheng Tong, Christopher A Quinto, Linlin Zhang, Priya Mohindra, Gang Bao
The ability to generate heat under an alternating magnetic field (AMF) makes magnetic iron oxide nanoparticles (MIONs) an ideal heat source for biomedical applications including cancer thermoablative therapy, tissue preservation, and remote control of cell function. However, there is a lack of quantitative understanding of the mechanisms governing heat generation of MIONs, and the optimal nanoparticle size for magnetic fluid heating (MFH) applications. Here, we show that MIONs with large sizes (>20 nm) have a specific absorption rate (SAR) significantly higher than that predicted by the widely used linear theory of MFH...
June 21, 2017: ACS Nano
https://www.readbyqxmd.com/read/28596262/optimal-surveillance-strategies-after-surgery-for-renal-cell-carcinoma
#3
REVIEW
Mark D Tyson, Sam S Chang
One in 5 patients who undergo surgical resection for clinically localized renal cell carcinoma (RCC) develop local and/or distant recurrences which, when detected early, may be amenable to salvage local and systemic therapies. When considering that approximately half of these recurrences will occur during the first 2 years, a clear rationale exists for optimizing surveillance strategies after surgery. Although there is a notable dearth of high-quality data on this subject, clinical principles can guide clinicians as they attempt to balance the burden of surveillance strategies with potential clinical benefit...
June 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28537410/-liver-hemangiomas-when-is-invasive-treatment-indicated
#4
V Třeška, T Skalický, V Liška, J Fichtl, J Brůha, M Skála, J Šebek, P Duras
INTRODUCTION: Liver hemangiomas are the most common benign tumors of the liver. Most are asymptomatic and are found accidentally by ultrasonography, computed tomography or magnetic resonance imaging of the abdomen. Liver hemangiomas usually do not need any treatment. Nevertheless, symptomatic, giant hemangiomas can be indicated for surgery, embolization or thermoablation. The aim of this study was to define based on our own experience and on the literature when and what treatment option should be indicated in patients suffering from liver hemangioma...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28523400/long-term-effect-of-thermoablative-fractional-co2-laser-treatment-as-a-novel-approach-to-urinary-incontinence-management-in-women-with-genitourinary-syndrome-of-menopause
#5
Pablo González Isaza, Kinga Jaguszewska, Jose Luis Cardona, Mariusz Lukaszuk
INTRODUCTION AND HYPOTHESIS: The aim of this study was to evaluate the long-term effect of thermoablative fractional CO2 laser (TACO2L) as an alternative treatment for early stages of stress urinary incontinence (SUI) in postmenopausal women with genitourinary syndrome of menopause. METHODS: A total of 161 postmenopausal patients (age 53.38 ± 5.1 years, range 45-65 years) with a clinical diagnosis of mild SUI were prospectively enrolled in the study. Patients received one treatment with TACO2L every 30-45 days, each treatment comprising four sessions, followed in all patients by a yearly treatment session at 12, 24 and 36 months...
May 18, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28383273/near-infrared-light-responsive-folate-targeted-gold-nanorods-for-combined-photothermal-chemotherapy-of-osteosarcoma
#6
Anna Li Volsi, Cinzia Scialabba, Valeria Vetri, Gennara Cavallaro, Mariano Licciardi, Gaetano Giammona
Folate-targeted gold nanorods (GNRs) are proposed as selective theranostic agents for osteosarcoma treatment. An amphiphilic polysaccharide based graft-copolymer (INU-LA-PEG-FA) and an amino derivative of the α,β-poly(N-2-hydroxyethyl)-d,l-aspartamide functionalized with folic acid (PHEA-EDA-FA), have been synthesized to act as coating agents for GNRs. The obtained polymer-coated GNRs were characterized in terms of size, shape, zeta potential, chemical composition, and aqueous stability. They protected the anticancer drug nutlin-3 and were able to deliver it efficiently in different physiological media...
April 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28348961/preoperative-visual-field-deficits-in-temporal-lobe-epilepsy
#7
Sanjeet S Grewal, William O Tatum, Paul W Brazis, Jerry J Shih, Robert E Wharen
Surgical resection and laser thermoablation have been used to treat medically refractory epilepsy with good results. However, they are not without risk. One of the most commonly reported complications of temporal lobe surgery is contralateral superior homonymous quadrantanopsia. We describe a patient with quadrantanopsia discovered as part of our recently modified protocol to workup patients prior to epilepsy surgery. This field cut was subtle and not detected on routine neurological examination. While we understand that this is a single case, we advocate for more judicious preoperative visual field examinations to truly characterize the incidence of postoperative visual field lesions...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/28348940/minimally-invasive-robotic-laser-corpus-callosotomy-a-proof-of-concept
#8
Harminder Singh, Walid I Essayed, Sayantan Deb, Caitlin Hoffman, Theodore H Schwartz
INTRODUCTION: We describe the feasibility of using minimally invasive robotic laser interstitial thermotherapy (LITT) for achieving an anterior two-thirds as well as a complete corpus callosotomy. METHODS: Ten probe trajectories were plotted on normal magentic resonance imaging (MRI) scans using the Brainlab Stereotactic Planning Software (Brainlab, Munich, Germany). The NeuroBlate® System (Monteris Medical, MN, USA) was used to conform the thermal burn to the corpus callosum along the trajectory of the probe...
February 10, 2017: Curēus
https://www.readbyqxmd.com/read/28236104/uterine-fibroid-therapy-using-interventional-radiology-mini-invasive-treatments-current-perspective
#9
REVIEW
Carlo Masciocchi, Francesco Arrigoni, Fabiana Ferrari, Aldo Victor Giordano, Sonia Iafrate, Ilaria Capretti, Ester Cannizzaro, Alfonso Reginelli, Anna Maria Ierardi, Chiara Floridi, Alessio Salvatore Angileri, Luca Brunese, Antonio Barile
Uterine fibroids are common benign tumors of unclear etiopathology that affect the female reproductive tract. They are responsible for considerable morbidity and deterioration of life quality, and may have a negative impact on the reproductive system as well. Besides surgery aided by uterus-saving techniques, several minimally invasive procedures are now available within the field of interventional radiology that represent a valid solution for women who desire pregnancy and relief from disease-specific symptomatology...
April 2017: Medical Oncology
https://www.readbyqxmd.com/read/28216972/laparoscopic-resection-vs-laparoscopic-radiofrequency-ablation-for-the-treatment-of-small-hepatocellular-carcinomas-a-single-center-analysis
#10
Marco Casaccia, Gregorio Santori, Giuliano Bottino, Pietro Diviacco, Enzo Andorno
AIM: To compare survival and recurrence after laparoscopic liver resection (LLR) and laparoscopic radiofrequency ablation (LRFA) for the treatment of small hepatocellular carcinoma (HCC). METHODS: Between June 1, 2005 and November 30, 2010, 46 patients (62.26 ± 8.55 years old; female/male: 12/34) treated for small HCC were enrolled following strict criteria. Patients with better liver function and larger tumors were referred for LLR (n = 24), while those with poorer liver function and multiple tumors were referred for LRFA (n = 22), and they were then followed for similar durations (44...
January 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28163939/isolated-liver-metastasis-in-h%C3%A3-rthle-cell-thyroid-cancer-treated-with-microwave-ablation
#11
Konstantinos Segkos, Carl Schmidt, Fadi Nabhan
Hürthle cell thyroid cancer (HCTC) is a less common form of differentiated thyroid cancer. It rarely metastasizes to the liver, and when it does, the metastasis is almost never isolated. Here we report a 62-year-old male with widely invasive Hürthle cell thyroid cancer, who underwent total thyroidectomy and received adjuvant treatment with I-131 with posttreatment scan showing no evidence of metastatic disease. His thyroglobulin however continued to rise after that and eventually an isolated liver metastasis was identified...
2017: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/28151029/radiofrequency-induced-thermotherapy-rfitt-in-a-porcine-liver-model-and-ex-vivo-great-saphenous-vein
#12
George E Badham, Scott J Dos Santos, Mark S Whiteley
AIMS: To investigate the thermal spread achieved in porcine liver when using an optimised radiofrequency ablation protocol and correlate findings with the effects seen in ex vivo great saphenous vein (GSV), in order to justify clinical use with the new treatment protocol. MATERIAL AND METHODS: Porcine liver and GSV sections were treated with radiofrequency-induced thermotherapy (RFiTT) using the following settings: 20 W at 1 s/cm (linear endovenous energy density; LEED 20 J/cm), 18 W at 1 s/cm (LEED 18 J/cm), 18 W at 3 s/cm (LEED 54 J/cm), 6 W interrupted pull-back 6 s stationary every 0...
February 2, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28112908/enhanced-photothermal-bactericidal-activity-of-the-reduced-graphene-oxide-modified-by-cationic-water-soluble-conjugated-polymer
#13
Linhong Xiao, Jinhua Sun, Libing Liu, Rong Hu, Huan Lu, Chungui Cheng, Yong Huang, Shu Wang, Jianxin Geng
Surface modification of graphene is extremely important for applications. Here, we report a grafting-through method for grafting water-soluble polythiophenes onto reduced graphene oxide (RGO) sheets. As a result of tailoring of the side chains of the polythiophenes, the modified RGO sheets, that is, RGO-g-P3TOPA and RGO-g-P3TOPS, are positively and negatively charged, respectively. The grafted water-soluble polythiophenes provide the modified RGO sheets with good dispersibility in water and high photothermal conversion efficiencies (ca...
February 3, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28007329/feasibility-of-real-time-intraprocedural-temperature-control-during-bone-metastasis-thermal-microwave-ablation-a-bicentric-retrospective-study
#14
Adrian Kastler, Alexandre Krainik, Linda Sakhri, Mireille Mousseau, Bruno Kastler
PURPOSE: To evaluate feasibility of using a thermocouple for temperature monitoring during microwave (MW) ablation of metastatic bone disease. MATERIALS AND METHODS: This retrospective study comprised 16 patients (8 men with mean age 63 y and 8 women with mean age 59 y) with 18 bone metastases treated with MW ablation using a thermocouple between March 2012 and October 2015. The mean maximum tumor size was 29.5 mm. MW ablation power was set between 15 W and 40 W and applied for 1-6 minutes...
March 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27989228/-thermoablation-therapy-in-the-treatment-of-benign-lesions
#15
Pál Ákos Deák, Dávid Ádám Korda, Attila Doros
INTRODUCTION: Depending on their size and location, some benign tumors can cause prolonged discomfort and even rupture and fatal bleeding in severe cases. Hitherto the therapeutic strategies for such lesions were observation, surgery and in selected cases transarterial embolization. AIM: Our aim was to present the possibilities of thermoablation for treating lesions. METHOD: Here we present interventions of four patients in Semmelweis University Department of Transplantation and Surgery...
December 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27978871/-interventional-bronchoscopies-for-the-treatment-of-112-cases-with-complex-malignant-central-airway-diseases-involved-in-bifurcation
#16
Hongwu Wang, Nan Zhang, Dongmei Li, Meimei Tao, Jieli Zhang, Hang Zou, Yunzhi Zhou, Sujuan Liang, Xiuyun Bai
BACKGROUND: It is very difficult to deal with the comprehensive central airway diseases, especially the malignant airway obstruction. The aim of this study is to explore the clinical effects of multiple interventional bronchoscopies for the treatment of 112 cases with comprehensive malignant central airway diseases so as to evaluate the clinical applications of thermoablation and cryosurgery. METHODS: The 112 cases with malignant airway diseases retrospectively reviewed for bronchoscopic interventions performed in more than two lesions of carina and/or bifurcation...
December 20, 2016: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/27811494/successful-treatment-of-persistent-pain-after-pectus-excavatum-repair-using-paravertebral-nerve-radiofrequency-thermoablation
#17
Hannah Noemi Ladenhauf, Ottokar Stundner, Rudolf Likar, Jörg Schnöll, Roman P Metzger
We present a case of a 25-year-old male patient suffering from severe prolonged pain after uneventful pectus excavatum repair that could be treated successfully by paravertebral nerve radiofrequency thermoablation. The patient was scheduled for a minimally invasive Nuss pectus excavatum repair. Surgical correction was performed under general anesthesia in combination with a thoracic peridural catheter. The immediate postoperative course was uneventful; however, the patient developed severe prolonged bilateral chest wall pain across segments T8 and T9...
January 1, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/27785974/gold-nanoprism-nanorod-face-off-comparing-the-heating-efficiency-cellular-internalization-and-thermoablation-capacity
#18
Gabriel Alfranca, Álvaro Artiga, Grazyna Stepien, María Moros, Scott G Mitchell, Jesús M de la Fuente
AIM: This work compares the synthesis, heating capability, cellular internalization and thermoablation capacity of two different types of anisotropic gold nanoparticles: gold nanorods (NRs) and nanoprisms (NPrs). METHODS: Both particles possess surface plasmon resonance absorption bands in the near-IR, and their heating efficiency upon irradiation with a continuous near-IR laser (1064 nm) was evaluated. The cellular internalization, location and toxicity of these PEG-stabilized NPrs and NRs were then assessed in the Vero cell line by transmission electron microscopy and inductively coupled plasma mass spectrometry analysis, and their ability to induce cell death upon laser irradiation was then evaluated and compared...
October 27, 2016: Nanomedicine
https://www.readbyqxmd.com/read/27780661/high-intensity-focused-ultrasound-and-radiation-therapy-induced-immuno-modulation-comparison-and-potential-opportunities
#19
REVIEW
Roberta Cirincione, Federica Maria Di Maggio, Giusi Irma Forte, Luigi Minafra, Valentina Bravatà, Laura Castiglia, Vincenzo Cavalieri, Giovanni Borasi, Giorgio Russo, Domenico Lio, Cristina Messa, Maria Carla Gilardi, Francesco Paolo Cammarata
In recent years, high-intensity focused ultrasound (HIFU) has emerged as a new and promising non-invasive and non-ionizing ablative technique for the treatment of localized solid tumors. Extensive pre-clinical and clinical studies have evidenced that, in addition to direct destruction of the primary tumor, HIFU-thermoablation may elicit long-term systemic host anti-tumor immunity. In particular, an important consequence of HIFU treatment includes the release of tumor-associated antigens (TAAs), the secretion of immuno-suppressing factors by cancer cells and the induction of cytotoxic T lymphocyte (CTL) activity...
February 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27738460/thrombosis-of-the-saphenous-vein-stump-after-varicose-vein-surgery
#20
Hiroto Rikimaru
We evaluated thrombus extension in the proximal stump of the saphenous vein at 6 days, 4 weeks, and 16 weeks after saphenous vein surgery performed between July 2013 and March 2014 (18 patients, 29 limbs, and 31 stumps) using duplex ultrasonography. All thrombotic events were classified as endovenous heat-induced thrombosis (EHIT). Thrombus was observed in 27 stumps (87.1%), with only four (12.9%) stumps remaining without thrombus on postoperative day 6. Thrombus as EHIT class 2 was observed in one stump and as EHIT class 3 in another; in the remaining 25 stumps, it was observed as EHIT class 1 postoperatively...
2016: Annals of Vascular Diseases
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