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https://www.readbyqxmd.com/read/28007329/feasibility-of-real-time-intraprocedural-temperature-control-during-bone-metastasis-thermal-microwave-ablation-a-bicentric-retrospective-study
#1
Adrian Kastler, Alexandre Krainik, Linda Sakhri, Mireille Mousseau, Bruno Kastler
PURPOSE: To evaluate feasibility of using a thermocouple for temperature monitoring during microwave (MW) ablation of metastatic bone disease. MATERIALS AND METHODS: This retrospective study comprised 16 patients (8 men with mean age 63 y and 8 women with mean age 59 y) with 18 bone metastases treated with MW ablation using a thermocouple between March 2012 and October 2015. The mean maximum tumor size was 29.5 mm. MW ablation power was set between 15 W and 40 W and applied for 1-6 minutes...
December 19, 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27989228/-thermoablation-therapy-in-the-treatment-of-benign-lesions
#2
Pál Ákos Deák, Dávid Ádám Korda, Attila Doros
INTRODUCTION: Depending on their size and location, some benign tumors can cause prolonged discomfort and even rupture and fatal bleeding in severe cases. Hitherto the therapeutic strategies for such lesions were observation, surgery and in selected cases transarterial embolization. AIM: Our aim was to present the possibilities of thermoablation for treating lesions. METHOD: Here we present interventions of four patients in Semmelweis University Department of Transplantation and Surgery...
December 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27978871/-interventional-bronchoscopies-for-the-treatment-of-112-cases-with-complex-malignant-central-airway-diseases-involved-in-bifurcation
#3
Hongwu Wang, Nan Zhang, Dongmei Li, Meimei Tao, Jieli Zhang, Hang Zou, Yunzhi Zhou, Sujuan Liang, Xiuyun Bai
BACKGROUND: It is very difficult to deal with the comprehensive central airway diseases, especially the malignant airway obstruction. The aim of this study is to explore the clinical effects of multiple interventional bronchoscopies for the treatment of 112 cases with comprehensive malignant central airway diseases so as to evaluate the clinical applications of thermoablation and cryosurgery. METHODS: The 112 cases with malignant airway diseases retrospectively reviewed for bronchoscopic interventions performed in more than two lesions of carina and/or bifurcation...
December 20, 2016: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/27811494/successful-treatment-of-persistent-pain-after-pectus-excavatum-repair-using-paravertebral-nerve-radiofrequency-thermoablation
#4
Hannah Noemi Ladenhauf, Ottokar Stundner, Rudolf Likar, Jörg Schnöll, Roman P Metzger
We present a case of a 25-year-old male patient suffering from severe prolonged pain after uneventful pectus excavatum repair that could be treated successfully by paravertebral nerve radiofrequency thermoablation. The patient was scheduled for a minimally invasive Nuss pectus excavatum repair. Surgical correction was performed under general anesthesia in combination with a thoracic peridural catheter. The immediate postoperative course was uneventful; however, the patient developed severe prolonged bilateral chest wall pain across segments T8 and T9...
January 1, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/27785974/gold-nanoprism-nanorod-face-off-comparing-the-heating-efficiency-cellular-internalization-and-thermoablation-capacity
#5
Gabriel Alfranca, Álvaro Artiga, Grazyna Stepien, María Moros, Scott G Mitchell, Jesús M de la Fuente
AIM: This work compares the synthesis, heating capability, cellular internalization and thermoablation capacity of two different types of anisotropic gold nanoparticles: gold nanorods (NRs) and nanoprisms (NPrs). METHODS: Both particles possess surface plasmon resonance absorption bands in the near-IR, and their heating efficiency upon irradiation with a continuous near-IR laser (1064 nm) was evaluated. The cellular internalization, location and toxicity of these PEG-stabilized NPrs and NRs were then assessed in the Vero cell line by transmission electron microscopy and inductively coupled plasma mass spectrometry analysis, and their ability to induce cell death upon laser irradiation was then evaluated and compared...
October 27, 2016: Nanomedicine
https://www.readbyqxmd.com/read/27780661/high-intensity-focused-ultrasound-and-radiation-therapy-induced-immuno-modulation-comparison-and-potential-opportunities
#6
REVIEW
Roberta Cirincione, Federica Maria Di Maggio, Giusi Irma Forte, Luigi Minafra, Valentina Bravatà, Laura Castiglia, Vincenzo Cavalieri, Giovanni Borasi, Giorgio Russo, Domenico Lio, Cristina Messa, Maria Carla Gilardi, Francesco Paolo Cammarata
In recent years, high-intensity focused ultrasound (HIFU) has emerged as a new and promising non-invasive and non-ionizing ablative technique for the treatment of localized solid tumors. Extensive pre-clinical and clinical studies have evidenced that, in addition to direct destruction of the primary tumor, HIFU-thermoablation may elicit long-term systemic host anti-tumor immunity. In particular, an important consequence of HIFU treatment includes the release of tumor-associated antigens (TAAs), the secretion of immuno-suppressing factors by cancer cells and the induction of cytotoxic T lymphocyte (CTL) activity...
February 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27738460/thrombosis-of-the-saphenous-vein-stump-after-varicose-vein-surgery
#7
Hiroto Rikimaru
We evaluated thrombus extension in the proximal stump of the saphenous vein at 6 days, 4 weeks, and 16 weeks after saphenous vein surgery performed between July 2013 and March 2014 (18 patients, 29 limbs, and 31 stumps) using duplex ultrasonography. All thrombotic events were classified as endovenous heat-induced thrombosis (EHIT). Thrombus was observed in 27 stumps (87.1%), with only four (12.9%) stumps remaining without thrombus on postoperative day 6. Thrombus as EHIT class 2 was observed in one stump and as EHIT class 3 in another; in the remaining 25 stumps, it was observed as EHIT class 1 postoperatively...
2016: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/27676657/a-cholinergic-sympathetic-pathway-primes-immunity-in-hypertension-and-mediates-brain-to-spleen-communication
#8
Daniela Carnevale, Marialuisa Perrotta, Fabio Pallante, Valentina Fardella, Roberta Iacobucci, Stefania Fardella, Lorenzo Carnevale, Raimondo Carnevale, Massimiliano De Lucia, Giuseppe Cifelli, Giuseppe Lembo
The crucial role of the immune system in hypertension is now widely recognized. We previously reported that hypertensive challenges couple the nervous drive with immune system activation, but the physiological and molecular mechanisms of this connection are unknown. Here, we show that hypertensive challenges activate splenic sympathetic nerve discharge to prime immune response. More specifically, a vagus-splenic nerve drive, mediated by nicotinic cholinergic receptors, links the brain and spleen. The sympathetic discharge induced by hypertensive stimuli was absent in both coeliac vagotomized mice and in mice lacking α7nAChR, a receptor typically expressed by peripheral ganglionic neurons...
2016: Nature Communications
https://www.readbyqxmd.com/read/27540292/using-ferromagnetic-nanoparticles-with-low-curie-temperature-for-magnetic-resonance-imaging-guided-thermoablation
#9
Vít Herynek, Karolína Turnovcová, Pavel Veverka, Tereza Dědourková, Pavel Žvátora, Pavla Jendelová, Andrea Gálisová, Lucie Kosinová, Klára Jiráková, Eva Syková
INTRODUCTION: Magnetic nanoparticles (NPs) represent a tool for use in magnetic resonance imaging (MRI)-guided thermoablation of tumors using an external high-frequency (HF) magnetic field. To avoid local overheating, perovskite NPs with a lower Curie temperature (T c) were proposed for use in thermotherapy. However, deposited power decreases when approaching the Curie temperature and consequently may not be sufficient for effective ablation. The goal of the study was to test this hypothesis...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27508328/laparoscopic-approach-for-thermoablation-microwave-in-the-treatment-of-hepatocellular-carcinoma-a-single-center-experience
#10
Salvatore Gruttadauria, Duilio Pagano, Alessandro Tropea, Davide Cintorino, Luisa Castellana, Pasquale Bonsignore, Calogero Ricotta, Gaetano Piccolo, Giovanni Vizzini, Angelo Luca
BACKGROUND: The surgical therapy of choice for hepatocellular carcinoma (HCC) is liver transplantation (LT) or hepatic resection, although only a small percentage of patients can undergo these procedures. Microwave thermal ablation (MWTA) can be an effective alternative treatment for HCC that complicates a cirrhotic liver disease, either as a final procedure or for downstaging patients on the waiting list for LT, or in combination with resective surgery to achieve oncological radicality...
October 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27502560/endothelial-progenitor-cells-as-shuttle-of-anticancer-agents
#11
Anna Laurenzana, Francesca Margheri, Anastasia Chilla', Alessio Biagioni, Giancarlo Margheri, Lido Calorini, Gabriella Fibbi, Mario Del Rosso
Cell therapies are treatments in which stem or progenitor cells are induced to differentiate into the specific cell type required to repair damaged or destroyed tissues. Following their discovery, endothelial progenitor cells (EPCs) have stimulated a worldwide interest as possible vehicles to perform an autologous cell-therapy of tumors. Taking into account the tumor-homing properties of EPCs, two different approaches to control cancer progression have been pursued by combining the cell-based therapy with gene therapy or with nanomedicine...
August 8, 2016: Human Gene Therapy
https://www.readbyqxmd.com/read/27494815/repeat-stereotactic-radiosurgery-as-salvage-therapy-for-locally-recurrent-brain-metastases-previously-treated-with-radiosurgery
#12
Will H McKay, Emory R McTyre, Catherine Okoukoni, Natalie K Alphonse-Sullivan, Jimmy Ruiz, Michael T Munley, Shadi Qasem, Hui-Wen Lo, Fei Xing, Adrian W Laxton, Stephen B Tatter, Kounosuke Watabe, Michael D Chan
OBJECTIVE There are a variety of salvage options available for patients with brain metastases who experience local failure after stereotactic radiosurgery (SRS). These options include resection, whole-brain radiation therapy, laser thermoablation, and repeat SRS. There is little data on the safety and efficacy of repeat SRS following local failure of a prior radiosurgical procedure. This study evaluates the clinical outcomes and dosimetric characteristics of patients who experienced tumor recurrence and were subsequently treated with repeat SRS...
August 5, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27444829/precoagulation-assisted-parenchyma-sparing-laparoscopic-liver-surgery-rationale-and-surgical-technique
#13
Elisa Francone, Elena Muzio, Luigi D'Ambra, Carlo Aschele, Teseo Stefanini, Cinzia Sani, Emilio Falco, Stefano Berti
BACKGROUND: For the treatment of both primary and metastatic liver tumors, laparoscopic parenchyma-sparing surgery is advocated to reduce postoperative liver failure and facilitate reoperation in the case of recurrence. However, atypical and wedge resections are associated with a higher amount of intraoperative bleeding than are anatomical resections, and such bleeding is known to affect short- and long-term outcomes. Beyond the established role of radiofrequency and microwave ablation in the setting of inoperable liver tumors, the application of thermoablative energy along the plane of the liver surface to be transected results in a zone of coagulative necrosis, possibly minimizing bleeding of the cut liver surface during parenchymal transection...
July 21, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27399482/203%C3%A2-insular-depth-electrode-in-pediatric-treatment-refractory-epilepsy
#14
Luke Tomycz, Ali Haider, Maura Hamilton, David B Clarke, Mark R Lee
INTRODUCTION: It has been increasingly recognized that the insular cortex plays an important role in frontotemporal epilepsy (FTE) in children. The insula, however, cannot properly by monitored with conventional subdural grids, and open surgical resection of the insula is technically difficult and often associated with significant morbidity. Stereotactically placed insular depth electrodes allow direct and comprehensive monitoring of this region, and can easily be replaced with a laser applicator for minimally invasive treatment via thermo-ablation...
August 2016: Neurosurgery
https://www.readbyqxmd.com/read/27273952/microwave-versus-saline-linked-radiofrequency-aquamantys-assisted-liver-resection-in-a-porcine-liver-resection-model-a-safety-and-feasibility-pilot-study
#15
COMPARATIVE STUDY
Dimitrios Kaparelos, Demetrios Moris, Michalis Kontos, Alexandros Papalampros, Athanasios Petrou, Christos Tsigris, Emmanouil Pikoulis, Nikolaos Kavantzas, Apostolos Papalois, Evangelos Felekouras
PURPOSE: The aim of this study was to compare the feasibility, efficacy and safety of microwave ablation and saline-linked radiofrequency (Aquamantys) in liver resection. METHODS: Sixteen domestic pigs (8 per group) underwent thermoablations. Group A consisted of 8 pigs in which microwave left lateral liver resection was performed. Group B consisted of 8 pigs which underwent left lateral liver resection by the Aquamantys system. After 28 days of close follow-up, the animals were sacrificed in order to study the macroscopic and microscopic findings of each intervention on the liver edge...
March 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/27271219/does-hepatobiliary-phase-sequence-qualitatively-outperform-unenhanced-t1-weighted-imaging-in-assessment-of-the-ablation-margin-24-hours-after-thermal-ablation-of-hepatocellular-carcinomas
#16
Nobuyuki Takeyama, Sirachat Vidhyarkorn, Dong Jin Chung, Surachate Siripongsakun, Hyun J Kim, David S K Lu, Steven S Raman
PURPOSE: To retrospectively determine whether hepatobiliary phase (HBP) sequence outperforms unenhanced T1-weighted imaging (uT1wI) in distinguishing the ablation margin (AM) from hepatocellular carcinoma (HCC) 24 h after thermoablation. MATERIAL AND METHODS: Ninety-one patients [mean age, 65.7 years; 68 M/23F] with 138 HCCs (>6 months follow-up) underwent pre- and postablation gadoxetate disodium-enhanced MRI. AM showed a hyperintense middle zone (MZ) surrounding central hypo- or hyperintense HCCs on uT1wI, and an intermediate-intense MZ encompassing central hypo- or hyperintense HCCs during HBP...
October 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27199230/photothermal-ablation-of-cancer-cells-using-folate-coated-gold-grapheme-oxide-composite
#17
Nicolò Mauro, Anna Li Volsi, Cinzia Scialabba, Mariano Licciardi, Gennara Cavallaro, Gaetano Giammona
OBJECTIVE: A new tumor targeted polymer-coated gold/graphene hybrid has been developed for achieving simultaneously thermoablation and chemoterapy of folate receptor-positive cancer cells. METHODS: The gold/graphene hybrid was prepared by depositing gold nanospheres onto graphene oxide and coating it with an inulin-folate conjugate. Paclitaxel was loaded by sonication. The hybrid was characterized by UV-Vis spectroscopy, DSC analysis and SEM microscopy. The cytotoxicity, thermoablation and anticancer activity were evaluated in vitro on MCF-7 and 16 HBE...
May 20, 2016: Current Drug Delivery
https://www.readbyqxmd.com/read/27126512/bipolar-radiofrequency-ablation-of-benign-thyroid-nodules-using-a-multiple-overlapping-shot-technique-in-a-3-month-follow-up
#18
Konstantin David Kohlhase, Yücel Korkusuz, Daniel Gröner, Christian Erbelding, Christian Happel, Wolfgang Luboldt, Frank Grünwald
Purpose The aim of this study was to evaluate the decrease of benign thyroid nodules after bipolar radiofrequency ablation (RFA) in a 3-month follow-up using a multiple overlapping shot technique ('MOST'). Methods A total of 18 patients with 20 symptomatic benign thyroid nodules (17 cold nodules, 3 hyperfunctioning nodules) were treated in one single session by bipolar RFA. Bipolar ablation was performed using MOST. The nodule volumes were measured prior to ablation and 3 months after the procedure using ultrasound...
August 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27099433/advances-in-local-ablation-of-malignant-liver-lesions
#19
REVIEW
Robert M Eisele
Local ablation of liver tumors matured during the recent years and is now proven to be an effective tool in the treatment of malignant liver lesions. Advances focus on the improvement of local tumor control by technical innovations, individual selection of imaging modalities, more accurate needle placement and the free choice of access to the liver. Considering data found in the current literature for conventional local ablative treatment strategies, virtually no single technology is able to demonstrate an unequivocal superiority...
April 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/26981915/thermoablation-of-bone-tumors
#20
K I Ringe, M Panzica, C von Falck
UNLABELLED: The aim of this article is to review the significance of percutaneous thermal ablation in the treatment of bone tumors. We describe available ablation techniques as well as advantages and disadvantages in specific settings. In detail, radiofrequency ablation (RFA), microwave ablation (MWA), laser ablation, high intensity focused ultrasound (HIFU) and cryoablation are presented. In the second part of this review curative and palliative indications for the treatment of benign and malignant bone tumors are discussed...
June 2016: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
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