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https://www.readbyqxmd.com/read/27906292/ultrafast-pulse-generation-in-a-mode-locked-erbium-chip-waveguide-laser
#1
Champak Khurmi, Nicolas Bourbeau Hébert, Wen Qi Zhang, Shahraam Afshar V, George Chen, Jérôme Genest, Tanya M Monro, David G Lancaster
We report mode-locked ~1550 nm output of transform-limited ~180 fs pulses from a large mode-area (diameter ~50 μm) guided-wave erbium fluorozirconate glass laser. The passively mode-locked oscillator generates pulses with 25 nm bandwidth at 156 MHz repetition rate and peak-power of 260 W. Scalability to higher repetition rate is demonstrated by transform-limited 410 fs pulse output at 1.3 GHz. To understand the origins of the broad spectral output, the laser cavity is simulated by using a numerical solution to the Ginzburg-Landau equation...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27901539/colloidal-molecules-assembled-from-binary-spheres-under-an-ac-electric-field
#2
Kelley Lynch Heatley, Fuduo Ma, Ning Wu
Colloidal particles are envisioned as analogues of atoms and molecules, however they often lack the complexities present in their counterparts. In this work, we report the assembly of colloidal molecules from a binary mixture of polystyrene spheres (1, 1.6, 2, and 4 μm) under an alternating current electric field. The rich family of assembled oligomers typically consists of a large sphere that is closely surrounded by a number of smaller petal particles, driven by the dipolar attraction between large and small particles...
November 30, 2016: Soft Matter
https://www.readbyqxmd.com/read/27883152/a-resettable-and-reprogrammable-biomolecular-keypad-lock-with-dual-outputs-based-on-glucose-oxidase-au-nanoclusters-prussian-blue-nanocomposite-films-on-an-electrode-surface
#3
Xue Yu, Menglu Li, Tianrui Li, Shuo Zhou, Hongyun Liu
In this work, electrochromic Prussian blue (PB) films were electrodeposited on the surface of indium tin oxide (ITO) electrodes, and a dispersion mixture of glucose oxidase (GOD), chitosan (CS) and gold nanoclusters (AuNCs) was then cast on the PB surface to form CS-AuNC-GOD/PB nanocomposite film electrodes. The blue PB component in the films could be changed into its colourless reduced form of Prussian white (PW) upon application of -0.2 V. The addition of glucose to the solution would produce H2O2 with the help of GOD in the films and oxygen in the solution, which could oxidize PW back to PB...
November 24, 2016: Nanoscale
https://www.readbyqxmd.com/read/27869838/analytical-comparison-of-pulses-generated-by-locking-three-and-five-longitudinal-modes-in-free-running-class-b-lasers
#4
Farzane Sharafi, Jafar Jahanpanah
We consider the coherent oscillation of five longitudinal modes, which leads to the coupling of modes in the frequency domain and generation of short pulses in the time domain. The aim is to audit the mechanism of mode locking in more detail by extending the analytical solution of the Maxwell-Bloch equations of motion from three to five mode states. The characteristics of pulses including height, repetition, and duration have been calculated for a five-mode class B laser, and the changes are compared with respect to the three-mode state...
November 20, 2016: Applied Optics
https://www.readbyqxmd.com/read/27869672/analysis-of-multi-antenna-gnss-receiver-performance-under-jamming-attacks
#5
Niranjana Vagle, Ali Broumandan, Gérard Lachapelle
Although antenna array-based Global Navigation Satellite System (GNSS) receivers can be used to mitigate both narrowband and wideband electronic interference sources, measurement distortions induced by array processing methods are not suitable for high precision applications. The measurement distortions have an adverse effect on the carrier phase ambiguity resolution, affecting the navigation solution. Depending on the array attitude information availability and calibration parameters, different spatial processing methods can be implemented although they distort carrier phase measurements in some cases...
November 17, 2016: Sensors
https://www.readbyqxmd.com/read/27848194/intramedullary-lengthening-nails-can-we-also-correct-deformities
#6
REVIEW
U Lenze, A H Krieg
Unlike external fixators, the use of solid intramedullary lengthening nails is restricted to defined anatomical preconditions, such as an adequate bone length. Furthermore, all deformity corrections except the lengthening procedure have to be implemented intraoperatively and cannot be adjusted postoperatively. Conversely, even complex deformity corrections can be performed using intramedullary devices after a thorough preoperative planning. For preparation of the intramedullary cavity as well as positioning of the lengthening nail according to the preoperative planning, reaming the medullary canal with rigid reamers which don't follow the line of least resistance is inevitable...
November 15, 2016: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/27788992/catheter-related-infections-in-patients-with-haematological-malignancies-novel-preventive-and-therapeutic-strategies
#7
REVIEW
Ramia Zakhour, Anne-Marie Chaftari, Issam I Raad
Central venous catheters are essential for the treatment of patients with haematological malignancies and the recipients of stem-cell transplant. This patient population is, however, at high risk for catheter-related bloodstream infections that can result in substantial morbidity, mortality, and health-care-associated costs. Efficient prevention, early diagnosis, and effective treatment are essential to providing the best care to these patients. Although confirming the catheter as a source of infection remains challenging, the Infectious Diseases Society of America definition of catheter-related bloodstream infection remains the most precise definition to use in these patients...
November 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27781479/phase-locked-patterns-of-the-kuramoto-model-on-3-regular-graphs
#8
Lee DeVille, Bard Ermentrout
We consider the existence of non-synchronized fixed points to the Kuramoto model defined on sparse networks: specifically, networks where each vertex has degree exactly three. We show that "most" such networks support multiple attracting phase-locked solutions that are not synchronized and study the depth and width of the basins of attraction of these phase-locked solutions. We also show that it is common in "large enough" graphs to find phase-locked solutions where one or more of the links have angle difference greater than π/2...
September 2016: Chaos
https://www.readbyqxmd.com/read/27774792/fast-nanoscale-surface-charge-mapping-with-pulsed-potential-scanning-ion-conductance-microscopy
#9
Ashley Page, David Perry, Philip Young, Daniel A Mitchell, Bruno G Frenguelli, Patrick R Unwin
A vast range of interfacial systems exhibit charge heterogeneities on the nanoscale. These differences in local surface charge density are challenging to visualize, but recent work has shown the scanning ion conductance microscope (SICM) to be a very promising tool to spatially resolve and map surface charge and topography via a hopping potential sweep technique with a single nanopipette probe, with harmonic modulation of a bias applied between quasi-reference counter electrodes in the nanopipette and bulk solution, coupled with lock-in detection...
October 24, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27763650/cu-sn-s-plasmonic-semiconductor-nanocrystals-for-ultrafast-photonics
#10
Qiangbing Guo, Meixi Ji, Yunhua Yao, Meng Liu, Zhi-Chao Luo, Shian Zhang, Xiaofeng Liu, Jianrong Qiu
Here, we show that solution-processed Cu-Sn-S semiconductor nanocrystals (NCs) demonstrate a tunable localized surface plasmon resonance band in the near infrared region, where strong saturable absorption occurs. A saturable absorber based on these plasmonic NCs enables the construction of a stable mode-locked femtosecond fiber laser operating at the telecommunication band.
October 20, 2016: Nanoscale
https://www.readbyqxmd.com/read/27754956/entrainment-maps-a-new-tool-for-understanding-properties-of-circadian-oscillator-models
#11
Casey O Diekman, Amitabha Bose
Circadian oscillators found across a variety of species are subject to periodic external light-dark forcing. Entrainment to light-dark cycles enables the circadian system to align biological functions with appropriate times of day or night. Phase response curves (PRCs) have been used for decades to gain valuable insights into entrainment; however, PRCs may not accurately describe entrainment to photoperiods with substantial amounts of both light and dark due to their reliance on a single limit cycle attractor...
October 17, 2016: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/27730778/antibiotic-lock-therapy-in-the-era-of-gram-negative-resistance
#12
Rajeev Soman, Neha Gupta, Mitesh Suthar, Jatin Kothari, Alan Almeida, Anjali Shetty, Camilla Rodrigues
BACKGROUND: Central-line-associated blood-stream infection (CLABSI) is a highly consequential nosocomial infection. The most effective management includes the removal of the infected catheter. Retention of the catheter and antibiotic lock therapy (ALT) along with systemic antibiotics may be attempted only if there are unusual extenuating circumstances. CLABSIs due to Gram-negative bacteria (GNB) is more common in our setting and the organisms are often highly resistant. Hence, there is a need to explore the use of novel antimicrobials for catheter lock solutions along with antibiofilm agents...
February 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27716755/-frequency-and-in-vitro-susceptibility-antiparasitic-of-blastocystis-hominis-from-patients-admitted-to-the-hospital-regional-lambayeque-peru
#13
Heber Silva-Díaz, Lorena Flores-Esqueche, Dunalia Llatas-Cancino, Génesis Guevara Vásquez, Teresa Silva-García
OBJECTIVE: To describe the frequency and antiparasitic in vitro susceptibility of Blastocystis hominis in patients admitted to theHospital Regional Lambayeque, Peru. MATERIAL AND METHODS: A cross-sectional study was conducted from January to August 2015 at 313 patients of all ages. B. hominis detection was performed on serial fecal samples by direct microscopic examination and microculture in modified Locke solution. The in vitro susceptibility testing against the drug metronidazole, nitazoxanide, trimethoprim-sulfamethoxazole and erythromycin was performed in 24 strains of B...
July 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/27693102/reconstructing-erp-amplitude-effects-after-compensating-for-trial-to-trial-latency-jitter-a-solution-based-on-a-novel-application-of-residue-iteration-decomposition
#14
Guang Ouyang, Werner Sommer, Changsong Zhou
Stimulus-locked averaged event-related potentials (ERPs) are among the most frequently used signals in Cognitive Neuroscience. However, the late, cognitive or endogenous ERP components are often variable in latency from trial to trial in a component-specific way, compromising the stability assumption underlying the averaging scheme. Here we show that trial-to-trial latency variability of ERP components not only blurs the average ERP waveforms, but may also attenuate existing or artificially induce condition effects in amplitude...
September 28, 2016: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/27687323/midterm-results-from-a-physician-sponsored-investigational-device-exemption-clinical-trial-evaluating-physician-modified-endovascular-grafts-for-the-treatment-of-juxtarenal-aortic-aneurysms
#15
Benjamin W Starnes, Rachel E Heneghan, Billi Tatum
OBJECTIVE: The objective of this study was to report midterm results of an ongoing physician-sponsored investigational device exemption pivotal clinical trial using physician-modified endovascular grafts (PMEGs) for treatment of patients with juxtarenal aortic aneurysms who are deemed unfit for open repair. METHODS: Data from a nonrandomized, prospective, consecutively enrolling investigational device exemption clinical trial were used. Data collection began on April 1, 2011, and data lock occurred on May 31, 2015, with outcomes analysis through December 31, 2015...
September 26, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27684516/improved-polymerase-chain-reaction-restriction-fragment-length-polymorphism-genotyping-of-toxic-pufferfish-by-liquid-chromatography-mass-spectrometry
#16
Hajime Miyaguchi
An improved version of a polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP) method for genotyping toxic pufferfish species by liquid chromatography/electrospray ionization mass spectrometry (LC/ESI-MS) is described. DNA extraction is carried out using a silica membrane-based DNA extraction kit. After the PCR amplification using a detergent-free PCR buffer, restriction enzymes are added to the solution without purifying the reaction solution. A reverse-phase silica monolith column and a Fourier transform high resolution mass spectrometer having a modified Kingdon trap analyzer are employed for separation and detection, respectively...
September 20, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27673745/regioselective-5-o-opening-of-conformationally-locked-3-5-o-di-tert-butylsilylene-d-galactofuranosides-synthesis-of-1%C3%A2-5-%C3%AE-d-galactofuranosyl-derivatives
#17
Mariano J Tilve, Carmen R Cori, Carola Gallo-Rodriguez
The use of thiogalactofuranoside as donors for the construction of internal Galf containing oligosaccharide is limited, probably due to the difficulty to functionalize thiogalactofuranoside derivatives showing O-2, O-3, and O-5 with similar reactivity. An efficient method for complete regioselective 5-O-opening of conformationally restricted 3,5-O-di-tert-butylsilylene-d-galactofuranoside derivatives was developed. The use of a solution nBu4NF (1.1 equiv) in CH2Cl2 on 6 gave the 5-OH free derivative 10 as the only product (90%)...
October 6, 2016: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/27671248/osmolyte-effects-on-the-growth-of-amyloid-fibrils
#18
Aswathy N Muttathukattil, Govardhan Reddy
Understanding the role of naturally occurring protective osmolytes, such as trimethylamine N-oxide (TMAO), in the growth of amyloid fibrils implicated in neurodegenerative diseases is important to prevent fibril growth. The effect of TMAO on the growth of amyloid fibrils formed by the Sup35 prion peptide NNQQNY is studied using molecular dynamics simulations. The free-energy surface for the growth of the protofibril shows three major basins, corresponding to the free state where the peptide is in solution, the docked state where the peptide in solution interacts with the surface of the protofibril, and the locked state where the peptide is tightly bound to the protofibril, becoming a part of the fibril...
October 17, 2016: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/27670267/the-clock-trial-a-double-blinded-randomized-controlled-trial-trisodium-citrate-30-and-minocycline-3-mg-ml-plus-edta-30-mg-ml-are-effective-and-safe-for-catheter-patency-maintenance-among-ckd-5d-patients-on-hemodialysis
#19
Marcus V S João Luiz, Cristoforo Scavone, Carmen Tzanno
Introduction Poor blood flow rate (PF) is highly prevalent among CKD 5D patients with long-term central venous catheters. Heparin catheter lock solutions are commonly used to maintain catheter patency, however the incidence of PF remains high. The purpose of the CLOCK Trial was to evaluate two catheter lock solutions on reduction of PF incidence. Methods Seventy-five CKD 5D patients on high-efficiency hemodialysis at the Integrated Centre of Nephrology (Guarulhos, Brazil) were randomized 1:1:1 to receive a lock solution combining minocycline 3 mg/mL with the anticoagulant/chelation agent EDTA 30 mg/mL (M-EDTA) or heparin 1000 IU/mL (H) or trisodium citrate 30% (TSC) vs...
September 26, 2016: Hemodialysis International
https://www.readbyqxmd.com/read/27642200/postseismic-gravity-change-after-the-2006-2007-great-earthquake-doublet-and-constraints-on-the-asthenosphere-structure-in-the-central-kuril-islands
#20
Shin-Chan Han, Jeanne Sauber, Fred Pollitz
Large earthquakes often trigger viscoelastic adjustment for years to decades depending on the rheological properties and the nature and spatial extent of coseismic stress. The 2006 Mw8.3 thrust and 2007 Mw8.1 normal fault earthquakes of the central Kuril Islands resulted in significant postseismic gravity change in GRACE but without a discernible coseismic gravity change. The gravity increase of ~4 µGal, observed consistently from various GRACE solutions around the epicentral area during 2007-2015, is interpreted as resulting from gradual seafloor uplift by ~6 cm produced by postseismic relaxation...
April 16, 2016: Geophysical Research Letters
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