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https://www.readbyqxmd.com/read/29228920/comparison-of-outcomes-between-emergent-start-and-planned-start-peritoneal-dialysis-in-incident-esrd-patients-a-prospective-observational-study
#1
Wen-Yi Li, Yi-Cheng Wang, Shang-Jyh Hwang, Shih-Hua Lin, Kwan-Dun Wu, Yung-Ming Chen
BACKGROUND: The clinical consequences of starting chronic peritoneal dialysis (PD) after emergent dialysis via a temporary hemodialysis (HD) catheter has rarely been evaluated within a full spectrum of treated end-stage renal disease (ESRD). We investigated the longer-term outcomes of patients undergoing emergent-start PD in comparison with that of other practices of PD or HD in a prospective cohort of new-onset ESRD. METHODS: This was a 2-year prospective observational study...
December 11, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29225970/dialysis-provision-and-implications-of-health-economics-on-peritoneal-dialysis-utilization-a-review-from-a-malaysian-perspective
#2
REVIEW
Mohd Rizal Abdul Manaf, Naren Kumar Surendra, Abdul Halim Abdul Gafor, Lai Seong Hooi, Sunita Bavanandan
End-stage renal disease (ESRD) is managed by either lifesaving hemodialysis (HD) and peritoneal dialysis (PD) or a kidney transplant. In Malaysia, the prevalence of dialysis-treated ESRD patients has shown an exponential growth from 504 per million population (pmp) in 2005 to 1155 pmp in 2014. There were 1046 pmp patients on HD and 109 pmp patients on PD in 2014. Kidney transplants are limited due to lack of donors. Malaysia adopts public-private financing model for dialysis. Majority of HD patients were treated in the private sector but almost all PD patients were treated in government facilities...
2017: International Journal of Nephrology
https://www.readbyqxmd.com/read/29224373/pharmacotherapy-and-treatment-options-for-hiv-associated-nephropathy
#3
Steven Menez, Mohamad Hanouneh, Blaithin A McMahon, Derek M Fine, Mohamed G Atta
Human immunodeficiency virus (HIV) remains a worldwide disease with significant mortality and morbidity. There are a multitude of HIV-related kidney diseases including HIV-associated nephropathy (HIVAN) most prominently. The risk of developing HIVAN increases with decreasing CD4 count, higher viral load, and based on genetic factors. The mortality rate for those with HIVAN-end stage renal disease (ESRD) remains 2.5-3 times higher than ESRD patient without HIVAN. Areas Covered: The epidemiology of HIVAN, particularly risk assessment will be explored in this review...
December 9, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29187194/treatment-effects-of-renin-angiotensin-aldosterone-system-blockade-on-kidney-failure-and-mortality-in-chronic-kidney-disease-patients
#4
Phisitt Vejakama, Atiporn Ingsathit, Gareth J McKay, Alexander P Maxwell, Mark McEvoy, John Attia, Ammarin Thakkinstian
BACKGROUND: Chronic kidney disease (CKD) is a leading cause of death before and after onset of end-stage renal disease (ESRD). Knowing treatments that can delay disease progression will lead to reduced mortality. We therefore aimed to estimate the effectiveness of renin angiotensin aldosterone system (RAAS) blockade on CKD progression. METHODS: We conducted a retrospective CKD cohort at Ubon Ratchathani province, Thailand from 1997 to 2011. ESRD was defined as estimated glomerular filtration rate (eGFR) <15 ml/min/1...
November 29, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29163492/t-cell-composition-of-the-lymph-node-is-associated-with-the-risk-for-early-rejection-after-renal-transplantation
#5
Burç Dedeoglu, Nicolle H R Litjens, Annelies E de Weerd, Frank Jmf Dor, Mariska Klepper, Derek Reijerkerk, Carla C Baan, Michiel G H Betjes
Background: The T-cell composition within the lymph node (LN) of end-stage renal disease (ESRD) patients differs from the composition within the circulation. Activation of the alloreactive T-cell response within secondary lymphoid organs is important after organ transplantation. However, to date no data are present on LN T-cell subsets and the risk for acute rejection after kidney transplantation. Methods: T cells from LNs of ESRD patients were analyzed for frequency of recent thymic emigrants, relative telomere length, expression of differentiation markers, and were related to the development of early acute rejection (EAR), occurring within 3 months after renal transplantation (RT)...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29162680/peritoneal-dialysis-in-orthotopic-liver-transplantation-recipients
#6
Nalinee Saiprasertkit, Camila Nihei, Joanne M Bargman
BACKGROUND: In many dialysis programs, there is resistance to initiating peritoneal dialysis (PD) in liver transplant patients needing renal replacement therapy. This retrospective study reviews the outcome of PD in liver transplant patients at a major transplantation and dialysis center. METHOD: We performed a retrospective cohort study in patients who underwent liver transplants and received PD between 1991 and 2016. Patient demographics, laboratory parameters, and adverse events were collected from our electronic database...
November 21, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29136724/-expert-consensus-for-the-diagnosis-and-treatment-of-patients-with-renal-impairment-of-multiple-myeloma
#7
(no author information available yet)
Renal impairment (RI) is a common complication of multiple myeloma (MM), which is presented as chronic kidney disease (CKD) or acute kidney injury (AKI). The typical pathological feature is cast nephropathy. Presently international system staging (ISS) is used in evaluating MM. Although the classic Durie-Salmon staging system could be still used in clinical practice, it may miss out some patients with renal impairment. For evaluations of RI in MM patients with CKD, it's recommended to assess the estimated glomerular filtration rate (eGFR) by creatinine based formula CKD-epidemiology collaboration (EPI) or modification of diet in renal disease(MDRD) and to stage the renal injuries according to 2013 Kidney Disease Improving Global Outcomes (KDIGO) CKD guidelines...
November 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29131054/heritability-of-end-stage-renal-disease-a-swedish-adoption-study
#8
Delshad Saleh Akrawi, MirNabi PirouziFard, Erik Fjellstedt, Jan Sundquist, Kristina Sundquist, Bengt Zöller
BACKGROUND/AIMS: The heritability of end-stage renal disease (ESRD) among adoptees has not been examined so far. By studying adoptees and their biological and adoptive parents, it is possible to differentiate between the genetic causes and environmental causes of familial aggregation. This nationwide study aimed to disentangle the genetic and shared environmental contribution to the familial transmission of ESRD. METHODS: We performed a family study for Swedish-born adoptees (born between 1945 until 1995) and their biological and adoptive parents...
November 9, 2017: Nephron
https://www.readbyqxmd.com/read/29123429/assessment-of-prescribed-medications-and-pattern-of-distribution-for-potential-drug-drug-interactions-among-chronic-kidney-disease-patients-attending-the-nephrology-clinic-of-lagos-university-teaching-hospital-in-sub-saharan-west-africa
#9
Olumuyiwa John Fasipe, Peter Ehizokhale Akhideno, Obiyo Nwaiwu, Alex Adedotun Adelosoye
Introduction: Life expectancy has increased significantly among chronic kidney disease (CKD) patients due to the extensive use of polypharmacy practice for medication prescriptions. This predisposes them to potential drug-drug interactions (DDIs), which can lead to an increase in morbidity, mortality, length of hospital stay, and health care cost. Methods: This was a 30-month retrospective study that reviewed the medical case records of consenting adult CKD patients from January 2014 to June 2016...
2017: Clinical Pharmacology: Advances and Applications
https://www.readbyqxmd.com/read/29123006/outcomes-of-simultaneous-peritoneal-dialysis-and-arteriovenous-fistula-placement-in-end-stage-renal-disease-patients
#10
Nosratollah Nezakatgoo, Albert Ndzengue, Manhunath Ramaiah, Elvira O Gosmanova
Peritoneal dialysis (PD) interruption requiring hemodialysis (HD) is not uncommon and its frequently abrupt nature prevents timely creation of permanent HD access and avoidance of central venous catheters (CVC). We retrospectively studied a cohort of 24 end-stage renal disease (ESRD) patients (mean age 50.7 years, 83.3% African-Americans, 58.3% females, time on dialysis interquartile range [IQR] 0 - 65 days) who had simultaneous PD catheter insertion and backup arteriovenous fistula (AVF) creation between January 1, 2012, and December 31, 2013...
November 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29116680/emergency-department-utilization-among-kidney-transplant-recipients-in-the-united-states
#11
Brendan P Lovasik, Rebecca Zhang, Jason M Hockenberry, Justin D Schrager, Stephen O Pastan, Andrew B Adams, Sumit Mohan, Christian P Larsen, Rachel E Patzer
Patients with End Stage Renal Disease (ESRD) use the emergency department (ED) at a 6-fold higher rate than U.S. adults. No national studies have described ED utilization rates among kidney transplant (KTx) recipients, and the factors associated with higher ED utilization. We examined a cohort of 132,725 adult KTx recipients in the United States Renal Data System (2005-2013). ED visits, hospitalization, and outpatient nephrology visits were obtained from Medicare claims databases. Nearly half (46.1%) of KTx recipients had at least one ED visit (1...
November 8, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/29095800/incidence-of-end-stage-renal-disease-attributed-to-diabetes-among-persons-with-diagnosed-diabetes-united-states-and-puerto-rico-2000-2014
#12
Nilka Rios Burrows, Israel Hora, Linda S Geiss, Edward W Gregg, Ann Albright
During 2014, 120,000 persons in the United States and Puerto Rico began treatment for end-stage renal disease (ESRD) (i.e., kidney failure requiring dialysis or transplantation) (1). Among these persons, 44% (approximately 53,000 persons) had diabetes listed as the primary cause of ESRD (ESRD-D) (1). Although the number of persons initiating ESRD-D treatment each year has increased since 1980 (1,2), the ESRD-D incidence rate among persons with diagnosed diabetes has declined since the mid-1990s (2,3). To determine whether ESRD-D incidence has continued to decline in the United States overall and in each state, the District of Columbia (DC), and Puerto Rico, CDC analyzed 2000-2014 data from the U...
November 3, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29064181/a-mayo-clinic-13-year-investigation-of-the-syndrome-of-rapid-onset-esrd-among-renal-transplant-recipients-an-analysis-of-the-implications-of-renal-allograft-biopsy-results
#13
REVIEW
Macaulay Amechi Onuigbo, Nneoma Agbasi
INTRODUCTION: We first described the syndrome of rapid onset end stage renal disease (SORO-ESRD), acute yet irreversible renal failure, in 2010. OBJECTIVE: The impact of SORO-ESRD renal allograft survival remains speculative and we plan to study this question. METHODS: A retrospective analysis of individual adult patient-level serum creatinine trajectories of ESRD patients on maintenance hemodialysis for >90 days at Mayo Clinic, Rochester, 2001-2013...
October 2017: Hemodialysis International
https://www.readbyqxmd.com/read/29055603/end-stage-renal-disease-after-pediatric-heart-transplantation-a-25-year-national-cohort-study
#14
Swati Choudhry, Vikas R Dharnidharka, Chesney D Castleberry, Charles W Goss, Kathleen E Simpson, Kenneth B Schechtman, Charles E Canter
BACKGROUND: End-stage renal disease (ESRD), defined as the need for chronic dialysis and/or kidney transplantation (KTx), is a known complication after heart transplant (HTx). However, factors associated with ESRD are not well elucidated. The objectives of this study were to determine the prevalence, risk factors, and outcomes associated with ESRD after pediatric HTx. METHODS: Scientific Registry of Transplant Recipients data were linked, using direct identifiers, to the United States Renal Data System to identify patients (aged ≤ 18 years) who underwent primary HTx between 1989 and 2013...
October 2, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29034143/decision-aids-to-increase-living-donor-kidney-transplantation
#15
Jennifer C Gander, Elisa J Gordon, Rachel E Patzer
PURPOSE OF REVIEW: For the more than 636,000 adults with end-stage renal disease (ESRD) in the U.S., kidney transplantation is the preferred treatment compared to dialysis. Living donor kidney transplantation (LDKT) comprised 31% of kidney transplantations in 2015, an 8% decrease since 2004. We aimed to summarize the current literature on decision aids that could be used to improve LDKT rates. RECENT FINDINGS: Decision aids are evidence-based tools designed to help patients and their families make difficult treatment decisions...
March 2017: Current Transplantation Reports
https://www.readbyqxmd.com/read/28981231/-home-dialysis-techniques-from-dream-to-reality
#16
S Treille, B Guillaume
The economic environment has pushed our political leaders to severely limit the health care spending. Belgian nephrologists have signed an agreement to attain more than 40 % of " alternative " dialysis techniques such as peritoneal dialysis (PD) and home hemodialysis (HHD). They will become unavoidable and major future therapy modalities. This article summarizes PD and HDD techniques in order to help health professionals and to inform them about innovative research in home dialysis techniques. It is a non exhaustive list of the many advantages, if not superiority, of the treatment of end stage renal disease (ESRD) at home instead of in-center HD...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28974524/risk-of-infective-endocarditis-in-patients-with-end-stage-renal-disease
#17
Mavish S Chaudry, Nicholas Carlson, Gunnar H Gislason, Anne-Lise Kamper, Marianne Rix, Vance G Fowler, Christian Torp-Pedersen, Niels E Bruun
BACKGROUND AND OBJECTIVES: Endocarditis is a serious complication in patients treated with RRT. The study aimed to examine incidence and risk factors of endocarditis in patients with ESRD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: The Danish National Registry on Regular Dialysis and Transplantation contains data on all Danish patients receiving renal replacement (hemodialysis, peritoneal dialysis, or kidney transplantation) for ESRD. Incidence of endocarditis was estimated for each RRT modality...
November 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28971660/-hemodialysis-present-innovations-for-patients-future
#18
REVIEW
Gai Milo, Ido Bogner, Younes Bathish, Moshe Lewin, Suheir Assady
End-stage renal disease (ESRD) is a major cause of morbidity and mortality worldwide. Survival of ESRD patients depends on renal replacement therapies, such as kidney transplantation and dialysis. Due to the shortage of potential kidney donors and patients' comorbidities, dialysis is the major therapeutic option offered to such patients. In this review, recent advances in hemodialysis and hemodiafiltration, and their potential impact on improving patient survival will be discussed.
September 2017: Harefuah
https://www.readbyqxmd.com/read/28969067/prevalence-and-survival-prognosis-of-prostate-cancer-in-patients-with-end-stage-renal-disease-a-retrospective-study-based-on-the-korea-national-database-2003-2010
#19
Sung Han Kim, Jae Young Joung, Yoon Seok Suh, Young Ae Kim, Jin Hyuk Hong, Tong Sun Kuark, Eun Sook Lee, Kang Hyun Lee
OBJECTIVE: The study was aimed to evaluate the prevalence and prognosis of prostate cancer (PC) and end-stage renal disease (ESRD), determine the risk factors for overall survival (OS) and PC-specific survival (CSS), and evaluate differences in PC-related clinical therapeutic patterns between patients with and without PC-ESRD. METHODS: This observational population study, performed at the National Cancer Center and Cancer Research Institute in Korea, included patients with PC and ESRD from the nationwide Korean Health Insurance System and Korean Central Cancer Registry data...
September 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28967967/optimizing-waiting-duration-for-renal-transplants-in-the-setting-of-renal-malignancy-is-2%C3%A2-years-too-long-to-wait
#20
Kevin A Nguyen, Jamil S Syed, Randy Luciano, Brian Shuch, Srinivas Vourganti
Background: For potential transplant recipients with a prior history of renal malignancy, no evidence-based recommendations currently exist with regard to waiting duration on dialysis. We aim to improve decision making by evaluating the impact of waiting duration on the outcomes of kidney cancer patients awaiting renal transplantation. Methods: The United States Renal Data System was used to identify patients with a known cause of end-stage renal disease (ESRD) from 1983 to 2007...
October 1, 2017: Nephrology, Dialysis, Transplantation
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