keyword
MENU ▼
Read by QxMD icon Read
search

Lanier

keyword
https://www.readbyqxmd.com/read/28225471/neuroanesthesiology-update
#1
Jeffrey J Pasternak, William L Lanier
We reviewed manuscripts published in 2016 that are related to the care of neurosurgical patients or the perioperative care of patients with neurological diseases. We address the broad categories of general neurosurgery and neuroanesthesiology, anesthetic neurotoxicity and neuroprotection, stroke, traumatic brain injury, and nervous system monitoring.
February 20, 2017: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/28201543/frozen-in-time-the-history-of-proteins
#2
Nicholas A Kovacs, Anton S Petrov, Kathryn A Lanier, Loren Dean Williams
No abstract text is available yet for this article.
February 15, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28197178/tdp-43-overexpression-impairs-presynaptic-integrity
#3
Lanier Heyburn, Charbel E-H Moussa
No abstract text is available yet for this article.
December 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/28185556/a-performance-study-of-the-impact-of-recombination-on-species-tree-analysis
#4
Zhiwei Wang, Kevin J Liu
BACKGROUND: The most widely used state-of-the-art methods for reconstructing species phylogenies from genomic sequence data assume that sampled loci are identically and independently distributed. In principle, free recombination between loci and a lack of intra-locus recombination are necessary to satisfy this assumption. Few studies have quantified the practical impact of recombination on species tree inference methods, and even fewer have used genomic sequence data for this purpose...
November 11, 2016: BMC Genomics
https://www.readbyqxmd.com/read/28165478/a-distinct-innate-lymphoid-cell-population-regulates-tumor-associated-t-cells
#5
Sarah Q Crome, Linh T Nguyen, Sandra Lopez-Verges, S Y Cindy Yang, Bernard Martin, Jennifer Y Yam, Dylan J Johnson, Jessica Nie, Michael Pniak, Pei Hua Yen, Anca Milea, Ramlogan Sowamber, Sarah Rachel Katz, Marcus Q Bernardini, Blaise A Clarke, Patricia A Shaw, Philipp A Lang, Hal K Berman, Trevor J Pugh, Lewis L Lanier, Pamela S Ohashi
Antitumor T cells are subject to multiple mechanisms of negative regulation. Recent findings that innate lymphoid cells (ILCs) regulate adaptive T cell responses led us to examine the regulatory potential of ILCs in the context of cancer. We identified a unique ILC population that inhibits tumor-infiltrating lymphocytes (TILs) from high-grade serous tumors, defined their suppressive capacity in vitro, and performed a comprehensive analysis of their phenotype. Notably, the presence of this CD56(+)CD3(-) population in TIL cultures was associated with reduced T cell numbers, and further functional studies demonstrated that this population suppressed TIL expansion and altered TIL cytokine production...
February 6, 2017: Nature Medicine
https://www.readbyqxmd.com/read/28143936/ebi3-regulates-the-nk-cell-response-to-mouse-cytomegalovirus-infection
#6
Helle Jensen, Shih-Yu Chen, Lasse Folkersen, Garry P Nolan, Lewis L Lanier
Natural killer (NK) cells are key mediators in the control of cytomegalovirus infection. Here, we show that Epstein-Barr virus-induced 3 (EBI3) is expressed by human NK cells after NKG2D or IL-12 plus IL-18 stimulation and by mouse NK cells during mouse cytomegalovirus (MCMV) infection. The induction of EBI3 protein expression in mouse NK cells is a late activation event. Thus, early activation events of NK cells, such as IFNγ production and CD69 expression, were not affected in EBI3-deficient (Ebi3(-/-)) C57BL/6 (B6) mice during MCMV infection...
January 31, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28113194/development-of-novel-3-d-printed-scaffolds-with-core-shell-nanoparticles-for-nerve-regeneration
#7
Se-Jun Lee, Wei Zhu, Lanier Heyburn, Margaret Nowicki, Brent Harris, Lijie Grace Zhang
A traumatic injury of peripheral nerves is serious clinical problem that may lead to major loss of nerve function, affecting quality of patient's life. Currently, nerve autograft is widely used to reconstruct the nerve gap. However, such surgical procedure suffers from many disadvantages including donor site morbidity and limited availability. In order to address these issues, neural tissue engineering has focused on the development of synthetic nerve scaffolds to support bridging a larger gap and improving nerve generation...
February 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28062065/expanding-the-mayo-clinic-proceedings-mission-introducing-mayo-clinic-proceedings-innovations-quality-outcomes-mcp-iq-o
#8
EDITORIAL
William L Lanier, Thomas C Gerber
No abstract text is available yet for this article.
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28045573/disparities-in-retention-in-hiv-care-among-hiv-infected-young-men-who-have-sex-with-men-in-the-district-of-columbia-2013
#9
Mercedes M Morales-Alemán, Jenevieve Opoku, Ashley Murray, Yzette Lanier, Michael Kharfen, Madeline Y Sutton
PURPOSE: Among young men who have sex with men (YMSM), aged 13-24 years, Blacks/African Americans and Hispanics/Latinos are disproportionately affected by HIV, accounting for 58% and 21%, respectively, of diagnoses of HIV infection in the United States. In the District of Columbia (DC), YMSM of color are also disproportionately affected by HIV. National goals are that 80% of HIV-infected persons be retained in HIV care. We analyzed DC surveillance data to examine retention among YMSM living with HIV infection in DC...
February 2017: LGBT Health
https://www.readbyqxmd.com/read/28006041/efficacy-and-safety-of-ciprofloxacin-plus-fluocinolone-in-otitis-media-with-tympanostomy-tubes-in-pediatric-patients-a-randomized-clinical-trial
#10
Zorik Spektor, Felix Pumarola, Khaleed Ismail, Brent Lanier, Iftikhar Hussain, John Ansley, Henry F Butehorn, Kenneth Esterhuizen, John Byers, Franklin Douglis, Bryan Lansford, F Javier Hernández
Importance: Acute otitis media with tympanostomy tubes (AOMT) in children commonly presents with otorrhea and negatively affects their daily activities. Objective: To evaluate the efficacy and safety of topical ciprofloxacin, 0.3%, plus fluocinolone acetonide, 0.025%, otic solution relative to ciprofloxacin, 0.3%, otic solution alone and fluocinolone acetonide, 0.025%, otic solution alone in the treatment of AOMT in children. Design, Setting, and Participants: Two twin multicenter, randomized, double-blind clinical trials with identical designs were conducted from June 24, 2011, through June 23, 2014, at ear, nose, and throat pediatric practices, general practices, hospitals, and clinical research centers...
December 22, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28005311/eltrombopag-a-thrombopoietin-mimetic-crosses-the-blood-brain-barrier-and-impairs-iron-dependent-hippocampal-neuron-dendrite-development
#11
T W Bastian, K A Duck, G C Michalopoulos, M J Chen, Z-J Liu, J R Connor, L M Lanier, M C Sola-Visner, M K Georgieff
: Essentials Potential neurodevelopmental side effects of thrombopoietin mimetics need to be considered. The effects of eltrombopag (ELT) on neuronal iron status and dendrite development were assessed. ELT crosses the blood-brain barrier and causes iron deficiency in developing neurons. ELT blunts dendrite maturation, indicating a need for more safety studies before neonatal use. SUMMARY: Background Thrombocytopenia is common in sick neonates. Thrombopoietin mimetics (e...
December 22, 2016: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/27984782/nk-cells-in-host-responses-to-viral-infections
#12
REVIEW
Viola C Lam, Lewis L Lanier
Natural killer (NK) cells are cytotoxic innate lymphocytes that play an important role in viral clearance. NK cell responses to viral infections were originally believed to be non-specific and lacked immune memory recall responses. It is now appreciated that NK cell responses to viral infections can be specific and in some cases memory recall responses are established. Increasing evidence also illuminates the complexity of NK cell interactions with both innate and adaptive immune cells. Here, we summarize the evidence for NK cell-specific memory responses to viral infections and the intricate reciprocal interactions between NK cells and other immune cells that dictate their activation and effector functions...
December 13, 2016: Current Opinion in Immunology
https://www.readbyqxmd.com/read/27910498/using-visar-to-assess-the-m-band-isotropy-in-hohlraums
#13
N E Lanier, J L Kline, J Morton
In laser based radiation flow experiments, drive variability can often overwhelm the physics sensitivity that one seeks to quantify. Hohlraums can help by providing a more symmetrized, Planckian-like source. However, at higher temperatures, the hohlraum's actual emission can deviate significantly from a truly blackbody, Lambertian source. At the National Ignition Facility (NIF), Dante provides the best quantification of hohlraum output. Unfortunately, limited diagnostic access coupled with NIF's natural symmetry does not allow for Dante measurements at more than two angles...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910339/atomic-physics-modeling-of-transmission-spectra-of-sc-doped-aerogel-foams-to-support-omega-experiments
#14
H M Johns, N E Lanier, J L Kline, C J Fontes, T S Perry, C L Fryer, C R D Brown, J W Morton, J D Hager, M E Sherrill
We present synthetic transmission spectra generated with PrismSPECT utilizing both the ATBASE model and the Los Alamos opacity library (OPLIB) to evaluate whether an alternative choice in atomic data will impact modeling of experimental data from radiation transport experiments using Sc-doped aerogel foams (ScSi6O12 at 75 mg/cm(3) density). We have determined that in the 50-200 eV Te range there is a significant difference in the 1s-3p spectra, especially below 100 eV, and for Te = 200 eV above 5000 eV in photon energy...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27810928/tracking-the-fate-of-antigen-specific-versus-cytokine-activated-natural-killer-cells-after-cytomegalovirus-infection
#15
Tsukasa Nabekura, Lewis L Lanier
Natural killer (NK) cells provide important host defense and can generate long-lived memory NK cells. Here, by using novel transgenic mice carrying inducible Cre expressed under the control of Ncr1 gene, we demonstrated that two distinct long-lived NK cell subsets differentiate in a mouse model of cytomegalovirus (MCMV) infection. NK cells expressing the MCMV-specific Ly49H receptor differentiated into memory NK cells by an activating signaling through Ly49H and Ly49H(-) NK cells differentiated into cytokine-activated NK cells by exposure to inflammatory cytokines during infection...
November 14, 2016: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27787875/posterior-fossa-syndrome-review-of-the-behavioral-and-emotional-aspects-in-pediatric-cancer-patients
#16
REVIEW
Jane C Lanier, Annah N Abrams
Medulloblastoma, the most common malignant brain tumor of childhood, occurs in the posterior fossa, the part of the intracranial cavity that contains the brainstem and the cerebellum. The cerebellum is involved in many complex aspects of human behavior and function, and when it is disrupted or insulted, this can lead to significant sequelae in children with posterior fossa tumors. A constellation of impairing and distressing symptoms, including mutism, ataxia/hypotonia, and emotional lability, develops in approximately 25% of children after the surgical resection of posterior fossa tumors...
October 27, 2016: Cancer
https://www.readbyqxmd.com/read/27780238/bacterial-etiology-and-risk-factors-associated-with-cellulitis-and-purulent-skin-abscesses-in-military-trainees
#17
Ryan C Johnson, Michael W Ellis, Carey D Schlett, Eugene V Millar, Patrick T LaBreck, Deepika Mor, Emad M Elassal, Jeffrey B Lanier, Cassie L Redden, Tianyuan Cui, Nimfa Teneza-Mora, Danett K Bishop, Eric R Hall, Kimberly A Bishop-Lilly, D Scott Merrell
: Military trainees are at high risk for skin and soft-tissue infections (SSTIs). Although Staphylococcus aureus is associated with purulent SSTI, it is unclear to what degree this pathogen causes nonpurulent cellulitis. To inform effective prevention strategies and to provide novel insights into SSTI pathogenesis, we aimed to determine the etiology of SSTI in this population. We conducted a prospective observational study in US Army Infantry trainees with SSTI (cutaneous abscesses and cellulitis) from July 2012 through December 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27757361/mesh-sutured-repairs-of-abdominal-wall-defects
#18
Steven T Lanier, Gregory A Dumanian, Sumanas W Jordan, Kyle R Miller, Nada A Ali, Stuart R Stock
: A new closure technique is introduced, which uses strips of macroporous polypropylene mesh as a suture for closure of abdominal wall defects due to failures of standard sutures and difficulties with planar meshes. METHODS: Strips of macroporous polypropylene mesh of 2 cm width were passed through the abdominal wall and tied as simple interrupted sutures. The surgical technique and surgical outcomes are presented. RESULTS: One hundred and seven patients underwent a mesh sutured abdominal wall closure...
September 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27757332/the-northwestern-abdominoplasty-scar-model-a-novel-human-model-for-scar-research-and-therapeutics
#19
Steven T Lanier, Jing Liu, Claudia Chavez-Munoz, Thomas A Mustoe, Robert D Galiano
There is a growing interest in the development and evaluation of therapeutic agents that improve the cosmetic appearance of scars. Existing nonhuman animal models to study scarring, while valuable, have well-acknowledged limitations, as it is accepted that the biology of human scarring differs significantly from scarring in other species. Moreover, human clinical trials of scarring require large numbers of subjects to achieve statistical power and are plagued by inherent intersubject variability because of the complex nature of wound healing in human beings...
September 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27747300/multi-body-site-microbiome-and-culture-profiling-of-military-trainees-suffering-from-skin-and-soft-tissue-infections-at-fort-benning-georgia
#20
Jatinder Singh, Ryan C Johnson, Carey D Schlett, Emad M Elassal, Katrina B Crawford, Deepika Mor, Jeffrey B Lanier, Natasha N Law, William A Walters, Nimfa Teneza-Mora, Jason W Bennett, Eric R Hall, Eugene V Millar, Michael W Ellis, D Scott Merrell
Skin and soft tissue infections (SSTIs) are common in the general population, with increased prevalence among military trainees. Previous research has revealed numerous nasal microbial signatures that correlate with SSTI development and Staphylococcus aureus colonization. Thus, we hypothesized that the ecology of the inguinal, oropharynx, and perianal regions may also be altered in response to SSTI and/or S. aureus colonization. We collected body site samples from 46 military trainees with purulent abscess (SSTI group) as well as from 66 asymptomatic controls (non-SSTI group)...
September 2016: MSphere
keyword
keyword
78314
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"