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High intensity focused ultrasound

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https://www.readbyqxmd.com/read/28543777/efficacy-and-safety-of-non-invasive-body-tightening-with-high-intensity-focused-ultrasound-hifu
#1
E J Ko, J Y Hong, T-R Kwon, E J Choi, Y-J Jang, S Y Choi, K H Yoo, S Y Kim, B J Kim
BACKGROUND: Noninvasive skin-tightening devices have become increasingly popular in response to increasing demand for improvements in skin laxity and tightening with minimal risk and recovery time. OBJECTIVE: We evaluated the efficacy and safety of HIFU for skin tightening in the face and body. METHODS: A total of 32 Korean subjects enrolled in this prospective clinical trial. The subjects were treated with HIFU to both cheeks, lower abdomen, and thigh...
May 22, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28540836/vocal-cord-paresis-following-single-session-high-intensity-focused-ablation-hifu-treatment-of-benign-thyroid-nodules-incidence-and-risk-factors
#2
Brian Hh Lang, Yu-Cho Woo, Keith Wan-Hang Chiu
BACKGROUND: Vocal cord paresis (VCP) may occur following high intensity focused ultrasound (HIFU) of thyroid nodules. We hypothesized its occurrence relates to the distance of the focus point (FP) of the HIFU beams from the recurrent laryngeal nerve (RLN) and the thermal power that this point received. Their relationships were examined. METHODS: One hundred and three patients who underwent HIFU for symptomatic benign thyroid nodule from October 2015 to March 2017 were analyzed...
May 24, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540825/the-role-of-t1-perfusion-based-classification-in-predicting-the-outcome-of-magnetic-resonance-guided-high-intensity-focused-ultrasound-treatment-of-adenomyosis
#3
Bilgin Keserci, Nguyen Minh Duc
OBJECTIVE: To assess the relationship between magnetic resonance (MR) T1 perfusion-based classification and the outcome of MR-guided high intensity focused ultrasound treatment of adenomyosis, defined as nonperfused volume (NPV) ratio. METHODS: The adenomyosis of 31 women was classified into group A (time-signal intensity [SI] curve of adenomyosis lower than that of the myometrium) and group B (time-SI curve of adenomyosis equal to or higher than that of the myometrium) on the basis of time-SI curves on dynamic contrast enhanced (DCE) MR images acquired at screening...
May 19, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540804/high-intensity-focused-ablation-hifu-of-single-benign-thyroid-nodule-rarely-alters-underlying-thyroid-function
#4
Brian H H Lang, Yu-Cho Woo, Keith Wan-Hang Chiu
BACKGROUND: High intensity focused ultrasound (HIFU) is a promising ablation technique for benign thyroid nodules. However, its effect on underlying thyroid function remains unknown. We aimed to evaluate the 6 months changes in serum thyroid stimulating hormone (TSH) and free thyroxine (FT4) after HIFU treatment. METHODS: Eighty-three consecutive patients who underwent single HIFU ablation for symptomatic benign thyroid nodule were analysed. Eligible patients had serum TSH and FT4 checked before treatment (baseline), 1 week, 3 and 6 months following HIFU treatment...
April 24, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28534375/effect-of-the-combination-treatment-of-high-intensity-focused-ultrasound-and-cryocare-knife-in-advanced-liver-cancer
#5
Yuan-Peng Zhai, Yan Wang
PURPOSE: To analyze the effect of the combination treatment of high-intensity focused ultrasound (HIFU) and cryocare knife in advanced liver cancer. METHODS: 74 patients with advanced liver cancer were divided into the observation group (40 cases) and the control group (34 cases). Patients in the control group were treated with simple transcatheter arterial chemoembolization (TACE), while those in the observation group were given the combination treatment of HIFU and cryocare knife...
March 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28523127/high-intensity-focused-ultrasound-hifu-ablation-of-benign-thyroid-nodules-a-systematic-review
#6
REVIEW
Brian Hung-Hin Lang, Arnold L H Wu
BACKGROUND: With an increasing number of imaging studies being done nowadays, the number of incidentally discovered thyroid nodules is expected to rise. Although many of these nodules are small and benign in nature, some do grow and may cause pressure and/or thyrotoxic symptoms. Surgical resection has traditionally been recommended for symptomatic nodules but is associated with risk of hypothyroidism, bleeding, infection, and nerve damage. High intensity focused ultrasound (HIFU) is one of the non-surgical thermal ablation techniques that may serve as an alternative in the treatment of benign thyroid nodules...
2017: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/28513733/polylactic-acid-nano-and-microchamber-arrays-for-encapsulation-of-small-hydrophilic-molecules-featuring-drug-release-via-high-intensity-focused-ultrasound
#7
Meiyu Gai, Johannes Frueh, Tianyi Tao, Arseniy V Petrov, Vladimir V Petrov, Evgeniy V Shesterikov, Sergei I Tverdokhlebov, Gleb B Sukhorukov
Long term encapsulation combined with spatiotemporal release for a precisely defined quantity of small hydrophilic molecules on demand remains a challenge in various fields ranging from medical drug delivery, controlled release of catalysts to industrial anti-corrosion systems. Free-standing individually sealed polylactic acid (PLA) nano- and microchamber arrays were produced by one-step dip-coating a PDMS stamp into PLA solution for 5 s followed by drying under ambient conditions. The wall thickness of these hydrophobic nano-microchambers is tunable from 150 nm to 7 μm by varying the PLA solution concentration...
May 17, 2017: Nanoscale
https://www.readbyqxmd.com/read/28512580/high-intensity-focused-ultrasound-circular-cyclocoagulation-in-glaucoma-a-step-forward-for-cyclodestruction
#8
REVIEW
Rodolfo Mastropasqua, Vincenzo Fasanella, Alessandra Mastropasqua, Marco Ciancaglini, Luca Agnifili
The ciliary body ablation is still considered as a last resort treatment to reduce the intraocular pressure (IOP) in uncontrolled glaucoma. Several ablation techniques have been proposed over the years, all presenting a high rate of complications, nonselectivity for the target organ, and unpredictable dose-effect relationship. These drawbacks limited the application of cyclodestructive procedures almost exclusively to refractory glaucoma. High-intensity focused ultrasound (HIFU), proposed in the early 1980s and later abandoned because of the complexity and side effects of the procedure, was recently reconsidered in a new approach to destroy the ciliary body...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28507052/correction-pulsed-high-intensity-focused-ultrasound-enhances-delivery-of-doxorubicin-in-a-preclinical-model-of-pancreatic-cancer
#9
(no author information available yet)
No abstract text is available yet for this article.
May 15, 2017: Cancer Research
https://www.readbyqxmd.com/read/28499816/tumor-ablation-using-low-intensity-ultrasound-and-sound-excitable-drug
#10
Ching-Hsuan Tung, Myung Shin Han, Young Kim, Jianjun Qi, Brian E O'Neill
The cell membrane is a semi-fluid container that defines the boundary of cells, and provides an enclosed environment for vital biological processes. A sound excitable drug (SED) that is non-cytotoxic to cells is developed to disrupt the plasma membrane under gentle ultrasound insonation, 1MHz, 1W/cm(2). The frequency and power density of insonation are within the physical therapy and medical imaging windows; thus the applied ultrasound is safe and not harmful to tissues. The insertion of SEDs into the plasma membrane is not toxic to cells; however, the intruding SEDs weaken the membrane's integrity...
May 10, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28487622/an-ultrasound-imaging-guided-robotic-hifu-ablation-experimental-system-and-accuracy-evaluations
#11
Chih Yu An, Jia Hao Syu, Ching Shiow Tseng, Chih-Ju Chang
In recent years, noninvasive thermal treatment by using high-intensity focused ultrasound (HIFU) has high potential in tumor treatment. The goal of this research is to develop an ultrasound imaging-guided robotic HIFU ablation system for tumor treatment. The system integrates the technologies of ultrasound image-assisted guidance, robotic positioning control, and HIFU treatment planning. With the assistance of ultrasound image guidance technology, the tumor size and location can be determined from ultrasound images as well as the robotic arm can be controlled to position the HIFU transducer to focus on the target tumor...
2017: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/28486218/design-of-a-hifu-array-for-the-treatment-of-deep-venous-thrombosis-a-simulation-study
#12
Petr Smirnov, Kullervo Hynynen
Deep Venous Thrombosis of the iliofemoral veins is a common and morbid disease, with the recommended interventional treatment carrying a high risk of hemorrhaging and complications. High Intensity Focused Ultrasound delivered with a single element transducer has been shown to successfully precipitate thrombolysis non-invasively in vitro and in vivo. However, in all previous studies damage to the veins or surrounding tissue has been observed. Using a simulation model of the human thigh, this study investigated whether a phased array device could overcome the large focal region limitations faced by single transducer treatment devices...
May 9, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28481444/when-east-meets-west
#13
Qide Han
In the current issue of BJOG, a report titled "Evaluation of HIFU Ablation for Uterine Fibroids: an IDEAL Prospective Exploration Study", was led by Professor Jinghe Lang, a member of Chinese Academy of Technology. While Chinese researchers have been leading the R&D of High-intensity focused ultrasound surgery technology and its clinical applications for more than 20 years, worldwide clinical dissemination has been hindered by the lack of systematic and high quality clinical evaluation. The study by Lang et al...
May 8, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28454842/inactivation-of-planktonic-escherichia-coli-by-focused-2-mhz-ultrasound
#14
Andrew A Brayman, Brian E MacConaghy, Yak-Nam Wang, Keith T Chan, Wayne L Monsky, Anna J McClenny, Thomas J Matula
This study was motivated by the desire to develop a non-invasive means to treat abscesses, and represents the first steps toward that goal. Non-thermal, high-intensity focused ultrasound (HIFU) was used to inactivate Escherichia coli (∼1 × 10(9) cells/mL) in suspension. Cells were treated in 96-well culture plate wells using 1.95-MHz ultrasound and incident focal acoustic pressures as high as 16 MPa peak positive and 9.9 MPa peak negative (free field measurements). The surviving fraction was assessed by coliform culture and the alamarBlue assay...
April 25, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28451817/morphometric-analysis-of-high-intensity-focused-ultrasound-induced-lipolysis-on-cadaveric-abdominal-and-thigh-skin
#15
Sugun Lee, Hee-Jin Kim, Hyun Jun Park, Hyoung Moon Kim, So Hyun Lee, Sung Bin Cho
Non-focused ultrasound and high-intensity focused ultrasound (HIFU) devices induce lipolysis by generating acoustic cavitation and coagulation necrosis in targeted tissues. We aimed to investigate the morphometric characteristics of immediate tissue reactions induced by 2 MHz, 13-mm focused HIFU via two-dimensional ultrasound images and histologic evaluation of cadaveric skin from the abdomen and thigh. Acoustic fields of a 2 MHz, 38-mm HIFU transducer were characterized by reconstruction of the fields using acoustic intensity measurement...
April 27, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28443145/initial-single-centre-canadian-experience-with-18f-fluoromethylcholine-positron-emission-tomography-computed-tomography-18f-fch-pet-ct-for-biochemical-recurrence-in-prostate-cancer-patients-initially-treated-with-curative-intent
#16
Simon Gauvin, Yannick Cerantola, Eléonore Haberer, Vincent Pelsser, Stephan Probst, Franck Bladou, Maurice Anidjar
INTRODUCTION: We sought to determine predictive factors (patient and prostate-specific antigen [PSA] characteristics) for 18F-fluoromethylcholine positron emission tomography-computed tomography (18F-FCH PET/CT) positivity in the context of biochemical recurrence after local treatment of prostate cancer (PCa) with curative intent. METHODS: This is a retrospective study including 60 18F-FCH PET/CT scans of patients with biochemical recurrence after initial radical prostatectomy (RP), external beam radiation therapy (EBRT), or focal high-intensity focused ultrasound (HIFU) with curative intent...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28439616/-high-intensity-focused-ultrasound-hifu-importance-in-the-treatment-of-prostate-cancer
#17
R Ganzer
BACKGROUND: High intensity focused ultrasound (HIFU) has been used since the beginning of the 1990s as an alternative treatment for prostate cancer. OBJECTIVE: Overview of the current status and critical review of the different indications for HIFU in the treatment of prostate cancer. MATERIAL AND METHODS: Review of the current literature on the indications, side effects, oncologic results and current guideline recommendations. RESULTS: The principle of HIFU is based on high energy sound waves, which lead to coagulation necrosis at the focal point...
April 24, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28437003/high-intensity-focused-ultrasound-for-the-treatment-of-adenomyosis-selection-criteria-efficacy-safety-and-fertility
#18
Lian Zhang, Fangwen Rao, Raymond Setzen
Adenomyosis is a disorder of uterus in which endometrial glands and stroma are present within the uterine musculature. The main clinical manifestations are dysmenorrhea and menorrhagia. Adenomyosis has a great impact on both the quality of life and fertility of women. The treatment of adenomyosis remains an immense challenge MATERIAL AND METHODS: Relevant articles were searched through MEDLINE, Pubmed between 2000 and March 2017. The search terms of adenomyosis, magnetic resonance imaging (MRI) features of adenomyosis, high intensity focused ultrasound (HIFU), Ultrasound-guided HIFU and MRgFUS were used...
April 24, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28436918/an-integrated-and-highly-sensitive-ultrafast-acoustoelectric-imaging-system-for-biomedical-applications
#19
Beatrice Berthon, Pierre-Marc Dansette, Mickael Tanter, Mathieu Pernot, Jean Provost
PURPOSE: Direct imaging of cardiac electrical activation is crucial to better understand and diagnose diseases linked to arrhythmias. This work presents an Ultrafast Acoustoelectric Imaging (UAI) system for direct and non-invasive ultrafast mapping of propagating current densities. MATERIALS AND METHODS: Acoustoelectric imaging is based on the acoustoelectric effect, the modulation of the medium's electrical impedance by a propagating ultrasonic wave. UAI triggers this effect with plane wave emissions to image current densities...
April 24, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28436860/effect-on-high-intensity-fields-of-a-tough-hydrophone-with-hydrothermal-pzt-thick-film-vibrator-and-titanium-front-layer
#20
Nagaya Okada, Shinichi Takeuchi
A novel tough hydrophone was fabricated by depositing hydrothermally synthesized lead zirconate titanate polycrystalline film on the back-side surface of a titanium plate. Our developed tough hydrophone resisted damage in a high-pressure field (15 MPa) at a focal point of a sinusoidal continuous wave driven by a concave high-intensity focused ultrasound (HIFU) transducer with up to 50 W of power input to the sound source. The hydrophone was suitable for the HIFU field, even though the hydrophone has a flat-shape tip of 3...
April 24, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
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