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https://www.readbyqxmd.com/read/28493342/rapid-deployment-aortic-valve-replacement-versus-standard-bioprosthesis-implantation
#1
Enrico Ferrari, Christelle Roduit, Pauline Salamin, Elena Caporali, Stefanos Demertzis, Piergiorgio Tozzi, Denis Berdajs, Ludwig von Segesser
OBJECTIVE: To compare the outcome and the 1-year hemodynamic results of the rapid-deployment Intuity valve versus the Perimount Magna bioprosthesis in matched populations. METHODS: Between March 2014 and May 2015, 32 patients underwent aortic valve replacement with the Intuity valve (Intuity-group). These patients were compared to a matched population of Perimount valves implanted during the same period of time (Perimount-group). Clinical data were compared and echocardiographic 1-year follow-up was performed...
May 11, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28359486/intraoperative-bioprosthetic-valve-dysfunction-causing-severe-mitral-regurgitation
#2
Philip Y K Pang, Susan Garwood, Sabet W Hashim
Structural degeneration of bioprosthetic valves usually occurs gradually over time. Failure of a bioprosthetic valve immediately after implantation is extremely rare. Possible causes include obstruction of valve leaflets from preserved subvalvular tissue during chordal-sparing mitral valve replacement (MVR) or strut entrapment by suture loops. We report 2 cases of acute bioprosthetic mitral valve (MV) dysfunction involving newly implanted Perimount Theon (Edwards Lifesciences, Irvine, CA) bioprostheses, causing severe transvalvular mitral regurgitation (MR)...
April 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28290163/morphological-and-clinical-findings-of-explanted-carpentier-edwards-perimount-pericardial-valve-in-the-aortic-position
#3
Jessica Forcillo, Pierre-Olivier Dionne, Philippe Demers, Louis P Perrault, Raymond Cartier, Denis Bouchard, Michel Carrier, Michel Pellerin
BACKGROUND: Freedom from structural valve deterioration (SVD) at 15 years with the Carpentier-Edwards (CE) Perimount pericardial valve in the aortic position was 60% in patients aged <60 years compared to 90% and 99% in patients aged 60-70 years and >70 years, respectively. The study aim was to focus on the causes of SVD requiring valve explant according to three different age groups: <60 years, 60-70 years, and >70 years. The short- and longterm clinical results of the patient cohort, followed for 25 years, are presented...
November 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28228313/significant-intra-valvular-pressure-loss-across-epic-supra-and-perimount-magna-supra-annular-designed-aortic-bioprostheses-in-patients-with-normal-aortic-size
#4
Jagdish C Mohan, Vishwas Mohan, Madhu Shukla, Arvind Sethi
Doppler-derived trans-prosthetic gradients are higher and the estimated effective valve area is smaller than the catheter-derived and directly measured hemodynamic values, mostly due to pressure recovery phenomenon. Pressure recovery to a varying extent is common to all prosthetic heart valves including bioprostheses. Pressure recovery-related differences are usually small except in patients with bileaflet metallic prosthesis, wherein high-pressure local jets across central orifice have been documented since long back and also in patients with narrow aortic root...
January 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28157718/in-vitro-comparative-assessment-of-decellularized-bovine-pericardial-patches-and-commercial-bioprosthetic-heart-valves
#5
Paola Aguiari, Laura Iop, Francesca Favaretto, Cátia Marisa Lourenco Fidalgo, Filippo Naso, Gabriella Milan, Vincenzo Vindigni, Michel Spina, Franco Bassetto, Andrea Bagno, Roberto Vettor, Gino Gerosa
Notwithstanding their wide exploitation, biological prosthetic heart valves are characterized by limited durability (10-15 years). The treatment of biological tissues with chemical crosslinking agents such as glutaraldehyde accounts for the enhanced risk of structural deterioration associated with the early failure of bioprosthetic valves. To overcome the shortcomings of the currently available solutions, adoption of decellularized biological tissues of animal origin has emerged as a promising approach. The present study aims to assess in vitro cardiovascular scaffolds composed of bovine pericardium decellularized with the novel TRITDOC (TRIton-X100 and TauroDeOxyCholic acid) procedure...
February 3, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28132979/reducing-prosthesis-patient-mismatch-with-edwards-magna-prosthesis-for-aortic-valve-replacement
#6
Yuta Kume, Tomoyuki Fujita, Satsuki Fukushima, Hiroki Hata, Yusuke Shimahara, Yorihiko Matsumoto, Kizuku Yamashita, Junjiro Kobayashi
BACKGROUND: Prosthesis-patient mismatch (PPM) is associated with increased mid-term and long-term mortality rates after aortic valve replacement (AVR). This study aimed to evaluate the efficacy of the Carpentier-Edwards Perimount Magna and Magna Ease (CEPMs) aortic bioprostheses to reduce the incidence of PPM.Methods and Results:Altogether, 282 consecutive patients (113 women, mean age 69.9±9.9 years) underwent AVR with a CEPMs between 2008 and 2015. They were divided into 3 groups based on the risk of PPM as a result of their body surface area and aortic annular diameter (BSA/AnnD ratio): low-risk (LR) group: 0...
March 24, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28104190/in%C3%A2-vitro-coronary-flow-after-transcatheter-aortic-valve-in-valve-implantation-a-comparison-of-2-valves
#7
Sina Stock, Michael Scharfschwerdt, Roza Meyer-Saraei, Doreen Richardt, Efstratios I Charitos, Hans-Hinrich Sievers, Thorsten Hanke
BACKGROUND: Transcatheter aortic valve-in-valve implantation (TAVI-ViV) is an evolving treatment strategy for degenerated surgical aortic valve bioprostheses (SAVBs). However, there is some concern regarding coronary obstruction, especially after TAVI-ViV in calcified SAVBs with externally mounted leaflets. We investigated in vitro coronary flow and hydrodynamics after TAVI-ViV using 2 modern SAVBs with externally and internally mounted leaflets. METHODS: Aortic root models including known risk factors for coronary obstruction served for the implantation of SAVBs with either externally mounted leaflets (St Jude Trifecta, size 25) or internally mounted leaflets (Edwards Perimount Magna Ease, size 25)...
February 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28040770/effect-of-bioprostheses-anti-calcification-treatment-comparative-follow-up-between-mitroflow-lx-and-magna-pericardial-xenografts-using-a-propensity-score-weighted-analysis
#8
Arnau Blasco-Lucas, Eduard Permanyer, María-Llanos Pérez, Juan Manuel Gracia-Baena, Remedios Ríos, Kelly Casós, Manuel Galiñanes
OBJECTIVES: The efficacy of anti-calcification treatment of bioprosthetic heart valves remains unclear. The aim of this study was to compare the clinical outcomes between Mitroflow LX valve, without anti-calcification treatment, and the Carpentier-Edwards Perimount Magna (P-Magna), with anti-calcification treatment. METHODS: Between 2005 and 2012, 625 consecutive patients underwent aortic valve replacement either with a Mitroflow LX (n = 329) or a P-Magna (n = 296)...
December 31, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27817951/transform-multicenter-experience-with-rapid-deployment-edwards-intuity-valve-system-for-aortic-valve-replacement-us-clinical-trial-performance-of-a-rapid-deployment-aortic-valve
#9
Glenn R Barnhart, Kevin D Accola, Eugene A Grossi, Y Joseph Woo, Mubashir A Mumtaz, Joseph F Sabik, Frank N Slachman, Himanshu J Patel, Michael A Borger, H Edward Garrett, Evelio Rodriguez, Patrick M McCarthy, William H Ryan, Francis G Duhay, Michael J Mack, W Randolph Chitwood
BACKGROUND: The TRANSFORM (Multicenter Experience With Rapid Deployment Edwards INTUITY Valve System for Aortic Valve Replacement) trial (NCT01700439) evaluated the performance of the INTUITY rapid deployment aortic valve replacement (RDAVR) system in patients with severe aortic stenosis. METHODS: TRANSFORM was a prospective, nonrandomized, multicenter (n = 29), single-arm trial. INTUITY is comprised of a cloth-covered balloon-expandable frame attached to a Carpentier-Edwards PERIMOUNT Magna Ease aortic valve...
October 15, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27773869/valve-in-valve-outcome-design-impact-of-a-pre-existing-bioprosthesis-on-the-hydrodynamics-of-an-edwards-sapien-xt-valve
#10
Christian Doose, Maximilian Kütting, Sandrine Egron, Pejman Farhadi Ghalati, Christoph Schmitz, Marc Utzenrath, Alexander Sedaghat, Buntaro Fujita, Thomas Schmitz-Rode, Stephan Ensminger, Ulrich Steinseifer
OBJECTIVES: Bioprosthetic aortic heart valves are increasingly implanted in younger patients. Therefore, a strategy for potential valve failure should be developed before implanting the 'first valve'. The goal of this in vitro study was to provide insight into the effects of the design of a bioprosthesis on a valve-in-valve implanted Sapien XT valve. METHODS: The hydrodynamic performance of a 23-mm Sapien XT valve implanted in Vascutek Aspire, Edwards Perimount, Medtronic Mosaic and St...
March 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27637422/outcome-and-performance-of-bioprosthetic-pulmonary-valve-replacement-in-patients-with-congenital-heart-disease
#11
Rio Nomoto, Lynn A Sleeper, Michele J Borisuk, Lisa Bergerson, Frank A Pigula, Sitaram Emani, Francis Fynn-Thompson, John E Mayer, Pedro J Del Nido, Christopher W Baird
OBJECTIVES: The goal of this single-center series was to assess differences in reintervention by the type of valve used for surgical bioprosthetic pulmonary valve replacement and to identify independent predictors of reintervention. METHODS: Data were retrospectively collected for 611 patients undergoing pulmonary valve replacement from 1996 to 2014. Kaplan-Meier estimation and Cox proportional hazards regression methodologies were used. RESULTS: The median age of patients was 17...
November 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27575598/current-knowledge-and-future-perspectives-regarding-stented-valves
#12
Giuseppe Santarpino, Jurij M Kalisnik, Theodor Fischlein, Steffen Pfeiffer
Aortic valve bioprostheses are commonly implanted in the current era (also in younger patients) as they may obviate the need for anticoagulation while providing better hemodynamic performance and a more favorable quality of life. The steady increase in the use of biological valves has prompted the development of several different models of conventional stented bioprostheses. At present, there are four main types of stented aortic bioprostheses that compete in the market: the LivaNova Crown PRT (LivaNova Group, Burnaby, Canada), the St...
October 2016: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/27570156/pulmonary-valve-replacement-with-a-trifecta-valve-is-associated-with-reduced-transvalvular-gradient
#13
Brian C Gulack, Ehsan Benrashid, Robert D B Jaquiss, Andrew J Lodge
BACKGROUND: Outcomes after surgical pulmonary valve replacement (PVR) in patients with congenital cardiac disease are limited by long-term valve deterioration, which may be hastened by turbulent flow. The use of the Trifecta valve (St. Jude Medical, Little Canada, MN) at our institution (Duke University Medical Center, Durham, NC) appears to result in low postimplantation transvalvular gradients. This study was performed to compare the early transvalvular gradient associated with the Trifecta valve with that associated with two other valves commonly used for PVR...
February 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27549228/performance-of-stented-biological-valves-for-right-ventricular-outflow-tract-reconstruction
#14
Christian Buchholz, Andreas Mayr, Ariawan Purbojo, Martin Glöckler, Okan Toka, Robert A Cesnjevar, André Rüffer
OBJECTIVES: This retrospective single-centre review presents mid- and long-term results of stented biological valves (SBVs) in the pulmonary position. METHODS: Fifty-two SBVs (17 Carpentier-Edwards Supraannular; 13 Carpentier-Edwards Perimount; 12 St. Jude Medical Trifecta; 4 Sorin Mitroflow; 4 Sorin Soprano; 2 Sorin More) were implanted between 2000 and 2015. The median valve size, patient age and weight were 23 mm (range 19-27), 22.8 years (range 5-77) and 62...
December 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27517167/hemodynamic-performance-of-endovascular-valves-as-valve-in-valve-in-small-stented-bioprosthesis
#15
Ralf-Uwe Kuehnel, Martin Hartrumpf, Michael Erb, Johannes M Albes
Background Endovascular valve in stented biological valve implantation (valve-in-valve transcatheter aortic valve implantation [TAVI ViV]) is increasingly becoming a valid option for bioprosthesis degeneration. TAVI implantation in small stented biological valves below 23 mm is controversially discussed. Reduced opening area and high gradients are typical objections against this procedure in cases of small bioprosthesis. Systematic studies about the hemodynamic performance of endovascular valves in small stented bioprosthesis, however, do not exist...
April 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/27491613/valve-type-size-and-deployment-location-affect-hemodynamics-in-an%C3%A2-in%C3%A2-vitro-valve-in-valve-model
#16
Prem A Midha, Vrishank Raghav, Jose F Condado, Ikechukwu U Okafor, Stamatios Lerakis, Vinod H Thourani, Vasilis Babaliaros, Ajit P Yoganathan
OBJECTIVES: The purpose of this study was to optimize hemodynamic performance of valve-in-valve (VIV) according to transcatheter heart valve (THV) type (balloon vs. self-expandable), size, and deployment positions in an in vitro model. BACKGROUND: VIV transcatheter aortic valve replacement is increasingly used for the treatment of patients with a failing surgical bioprosthesis. However, there is a paucity in understanding the THV hemodynamic performance in this setting...
August 8, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27491542/outcomes-of-surgical-aortic-valve-replacement-using-carpentier-edwards-perimount-bioprosthesis-series-in-elderly-patients-with-severe-aortic-valve-stenosis-a-retrospective-cohort-study
#17
Naritomo Nishioka, Akira Yamada, Kosuke Ujihira, Yutaka Iba, Ryushi Maruyama, Eiichiro Hatta, Yoshihiko Kurimoto, Katsuhiko Nakanishi
OBJECTIVE: We sought to compare the outcomes of Carpentier-Edwards PERIMOUNT (CEP), Magna and Magna Ease valves in Japanese elderly patients with severe aortic valve stenosis (AS). METHODS: We retrospectively identified 136 patients (mean age 76.61 ± 5.5 years old) who had undergone isolated surgical aortic valve replacement (SAVR) using CEP, Magna, and Magna Ease valves at a single institution, from January 2001 to December 2013. We compared the valves according to their survival rates, freedom from major adverse cardiovascular and cerebrovascular events (MACCE), and durability and hemodynamic performance by echocardiographic data...
December 2016: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27423336/effect-of-aortic-pericardial-valve-choice-on-outcomes-and-left-ventricular-mass-regression-in-patients-with-left-ventricular-hypertrophy
#18
Fraser D Rubens, Yen-Yen Gee, Janet M C Ngu, Li Chen, Ian G Burwash
OBJECTIVES: We sought to assess the effect of 2 contemporary pericardial valves on left ventricular mass regression and clinical outcomes after aortic valve replacement (AVR) in patients with aortic stenosis (AS). METHODS: Patients were followed postoperatively in a dedicated valve clinic. A propensity score was derived for each patient and used to adjust all analyses. Longitudinal analysis was performed using a repeated measures growth curve model. Survival analysis was assessed with a Cox proportional hazards model...
November 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27343502/near-catastrophic-accelerated-structural-degeneration-of-the-perimount-magna-pericardial-bioprosthesis-in-children
#19
Ranjit Philip, T K Susheel Kumar, B Rush Waller, Mia McCoy, Christopher J Knott-Craig
Experience with pericardial bioprostheses in young patients is limited. Accelerated degeneration of the Mitroflow valve has recently been reported. We report early accelerated structural valve degeneration with the Perimount Magna bioprosthesis, which has not been previously reported. Young patients with the Magna bioprosthesis are at high risk for rapid progression to severe stenosis, which underscores their need for more vigilant surveillance. The benefits and risks of these bioprosthetic valves must be weighed carefully when options for replacement in these young patients are discussed...
July 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27342209/transfemoral-valve-in-valve-transcatheter-aortic-valve-implantation-tavi-in-a-patient-with-previous-endovascular-aortic-repair-evar
#20
Neil Ruparelia, Vasileios F Panoulas, Angela Frame, Anthony W Nathan, Ben Ariff, Usman Jaffer, Nilesh Sutaria, Andrew Chukwuemeka, Ghada W Mikhail, Iqbal S Malik
A 90-year-old man presented with increasing exertional breathlessness. He had previous implantation of a Perimount bioprosthetic aortic valve (Edwards Lifesciences) and coronary artery bypass graft surgery. Due to severe transvalvular bioprosthetic regurgitation with preserved left ventricular dimensions and ejection fraction, the heart team decided on valve-in- valve transcatheter aortic valve implantation via the transfemoral route in view of the patient's prohibitively high surgical and anesthetic risk. The patient had an uncomplicated recovery and was symptomatically much improved at 3-month follow-up...
July 2016: Journal of Invasive Cardiology
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