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https://www.readbyqxmd.com/read/27936438/stressful-life-transitions-and-wellbeing-a-comparison-of-the-stress-buffering-hypothesis-and-the-social-identity-model-of-identity-change
#1
Nurul F Praharso, Morgan J Tear, Tegan Cruwys
The relationship between stressful life transitions and wellbeing is well established, however, the protective role of social connectedness has received mixed support. We test two theoretical models, the Stress Buffering Hypothesis and the Social Identity Model of Identity Change, to determine which best explains the relationship between social connectedness, stress, and wellbeing. Study 1 (N=165) was an experiment in which participants considered the impact of moving cities versus receiving a serious health diagnosis...
November 29, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27936333/alcohol-use-disorder-in-older-adults-challenges-in-assessment-and-treatment
#2
Mary C DiBartolo, Judith M Jarosinski
Alcohol use disorder (AUD) is a common, under-recognized, and under-treated health concern in older adults. Its prevalence is expected to reach unprecedented levels as the U.S. population ages; consequently, it is poised to place a significant burden on the healthcare system. Given the growing body of evidence regarding the patterns of use in this age group and the serious consequences of its misuse, it is critical that nurses and other healthcare providers assess for AUD in order to identify older adults in need of treatment...
December 9, 2016: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/27936127/interactions-between-thermal-acclimation-growth-rate-and-phylogeny-influence-prochlorococcus-elemental-stoichiometry
#3
Adam C Martiny, Lanying Ma, Céline Mouginot, Jeremy W Chandler, Erik R Zinser
Variability in plankton elemental requirements can be important for global ocean biogeochemistry but we currently have a limited understanding of how ocean temperature influences the plankton C/N/P ratio. Multiple studies have put forward a 'translation-compensation' hypothesis to describe the positive relationship between temperature and plankton N/P or C/P as cells should have lower demand for P-rich ribosomes and associated depressed QP when growing at higher temperature. However, temperature affects many cellular processes beyond translation with unknown outcomes on cellular elemental composition...
2016: PloS One
https://www.readbyqxmd.com/read/27936110/women-s-perceived-reasons-for-their-excessive-postpartum-weight-retention-a-qualitative-interview-study
#4
Anne Christenson, Eva Johansson, Signy Reynisdottir, Jarl Torgerson, Erik Hemmingsson
INTRODUCTION: Obesity in Sweden has doubled to 14% over the last 20 years. New strategies for treatment and prevention are needed. Excessive gestational weight gain has been found to contribute substantially to obesity, and there is a consistent association between postpartum weight retention and obesity later in life. We aimed to explore what factors women perceive as reasons for having substantial postpartum weight retention, to identify areas for new and improved interventions. METHODS: Qualitative interview study (semi-structured) using an emergent design...
2016: PloS One
https://www.readbyqxmd.com/read/27935987/patient-reported-treatment-satisfaction-with-rivaroxaban-for-stroke-prevention-in-atrial-fibrillation-a-french-observational-study-the-safari-study
#5
Olivier Hanon, Edouard Chaussade, Pierre Gueranger, Elise Gruson, Sabrina Bonan, Alain Gay
BACKGROUND: For antithrombotic treatments, Patient Reported Outcomes (PRO) and patient satisfaction with treatment are essential data for physicians because of the strong relationship between patient satisfaction and adherence to treatment. The impact of rivaroxaban on patient satisfaction and quality of life was not sufficiently documented in phase III studies. There is a need for further data in this field especially in real life conditions. METHODS: The SAFARI study is composed of patients with non-valvular atrial fibrillation (AF), previously treated with vitamin K antagonist (VKA) and switched to rivaroxaban...
2016: PloS One
https://www.readbyqxmd.com/read/27935957/intracellular-zn-ii-intoxication-leads-to-dysregulation-of-the-perr-regulon-resulting-in-heme-toxicity-in-bacillus-subtilis
#6
Pete Chandrangsu, John D Helmann
Transition metal ions (Zn(II), Cu(II)/(I), Fe(III)/(II), Mn(II)) are essential for life and participate in a wide range of biological functions. Cellular Zn(II) levels must be high enough to ensure that it can perform its essential roles. Yet, since Zn(II) binds to ligands with high avidity, excess Zn(II) can lead to protein mismetallation. The major targets of mismetallation, and the underlying causes of Zn(II) intoxication, are not well understood. Here, we use a forward genetic selection to identify targets of Zn(II) toxicity...
December 9, 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27935561/patterns-of-change-and-stability-in-caregiver-burden-and-life-satisfaction-from-1%C3%A2-to%C3%A2-2%C3%A2-years-after-severe-traumatic-brain-injury-a%C3%A2-norwegian-longitudinal-study
#7
Unn Sollid Manskow, Oddgeir Friborg, Cecilie Røe, Mary Braine, Elin Damsgard, Audny Anke
OBJECTIVE: To assess burden and life satisfaction in family members of patients with severe traumatic brain injury (sTBI) at 1 and 2 years post-injury, examine if change in burden can be predicted by family member and patient demographics, patient's functional status, family members social network or level of burden at 1 year. METHODS: Prospective national multicenter study. Self-report from family members, patient data collected from a national cohort study on patients with sTBI...
December 8, 2016: NeuroRehabilitation
https://www.readbyqxmd.com/read/27935345/using-health-psychology-techniques-to-manage-chronic-physical-symptoms
#8
Elizabeth Barley, Victoria Lawson
Chest pain and palpitations, non-malignant pain, breathlessness and fatigue often endure despite the receipt of appropriate nursing and medical care. This is distressing for patients, impacts on their quality of life and ability to function and is associated with high healthcare usage and costs. The cognitive behavioural approach offers nurses a model to understand how people's perceptions and beliefs and their emotional, behavioural and physiological reactions are linked. Common 'thinking errors' which can exacerbate symptom severity and impact are highlighted...
December 8, 2016: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/27935091/fabrication-of-complete-dentures-in-three-visits-using-existing-prosthesis-a-simplified-technique-for-geriatric-patients
#9
Rahul S Kulkarni, Ravindra S Pawar
Complete edentulism often limits patients' ability to masticate and perform other oral functions, resulting in a reduction of oral-health-related quality of life. Although the two-implant mandibular overdenture may be considered as a minimum standard of treatment of complete edentulism, patients often prefer conventional complete dentures due to cost and surgical procedures related to implant supported dentures. Many complete denture patients may have limited access to dental care due to socioeconomic or health issues, hence there is a need in simplification of complete denture fabrication...
December 9, 2016: Special Care in Dentistry
https://www.readbyqxmd.com/read/27935062/what-explains-high-life-satisfaction-in-men-living-with-duchenne-muscular-dystrophy-a-preliminary-study-to-inform-psychological-intervention
#10
Christopher D Graham, Michael R Rose
INTRODUCTION: There are increasing numbers of men with DMD (mDMD). For those struggling to live with the condition, psychological interventions may be helpful. However, it is unclear how these should be tailored for mDMD. To inform intervention, this study assessed whether 2 well-validated psychological models (Leventhal Self-Regulatory Model; Psychological Flexibility Model) could explain variation in life satisfaction (LS). METHODS: Sixteen mDMD, aged 18-43, completed an online survey comprised of questionnaire measures of LS, mood, and both psychological models: Illness Perceptions (Leventhal Self-Regulatory Model); engagement in meaningful activity, and acceptance/awareness of difficult thoughts and feelings (Psychological Flexibility Model)...
December 9, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27934951/biological-marks-of-early-life-socioeconomic-experience-is-detected-in-the-adult-inflammatory-transcriptome
#11
Raphaële Castagné, Michelle Kelly-Irving, Gianluca Campanella, Florence Guida, Vittorio Krogh, Domenico Palli, Salvatore Panico, Carlotta Sacerdote, Rosario Tumino, Jos Kleinjans, Theo de Kok, Soterios A Kyrtopoulos, Thierry Lang, Silvia Stringhini, Roel Vermeulen, Paolo Vineis, Cyrille Delpierre, Marc Chadeau-Hyam
Consistent evidence is accumulating to link lower socioeconomic position (SEP) and poorer health, and the inflammatory system stands out as a potential pathway through which socioeconomic environment is biologically embedded. Using bloodderived genome-wide transcriptional profiles from 268 Italian participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, we evaluated the association between early life, young and later adulthood SEP and the expression of 845 genes involved in human inflammatory responses...
December 9, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27934841/aeromonas-hydrophila-meningitis-and-fulminant-sepsis-in-preterm-newborn-a-case-report-and-review-of-literature
#12
A Kali, R Kalaivani, Pmv Charles, K S Seetha
Neonatal meningitis is a lethal infection occurring in the 1st month of life. The risk of developing permanent neurological sequels is high among the neonates who survive. Bacterial pathogens are commonly associated with this condition. Aeromonas is a Gram-negative bacteria of aquatic habitat. Although isolation of Aeromonas species from neonates with blood stream infection is infrequently reported, neonatal meningitis caused by Aeromonas is exceedingly rare. We present a case of fulminant sepsis and meningitis caused by Aeromonas hydrophila in a preterm newborn male...
October 2016: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27934629/the-work-environment-of-junior-doctors-their-perspectives-and-coping-strategies
#13
Tzong-Yang Pan, Howard S Fan, Cathy A Owen
OBJECTIVE: This study explores the associations between psychological distress in junior doctors and their work environment and how they cope with work stressors. METHODS: A cross-sectional survey designed by Health Education and Training Institute was delivered in 2014 to over 1900 junior doctors across 15 hospital networks through Australian Capital Territory and New South Wales. Psychological distress was evaluated using the Kessler Psychological Distress Scale-10 (K10)...
December 1, 2016: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/27934581/severe-acute-respiratory-infection-caused-by-swine-influenza-virus-in-a-child-necessitating-extracorporeal-membrane-oxygenation-ecmo-the-netherlands-october-2016
#14
Pieter L A Fraaij, Enno D Wildschut, Robert J Houmes, Corien M Swaan, Christian J Hoebe, H C C de Jonge, Paulien Tolsma, Isme de Kleer, Suzan D Pas, Bas B Oude Munnink, My V T Phan, Theo M Bestebroer, R Shanty Roosenhoff, Jeroen J A van Kampen, Matthew Cotten, Nancy Beerens, Ron A M Fouchier, Johannes H van den Kerkhof, Aura Timen, Marion P Koopmans
In October 2016, a severe infection with swine influenza A(H1N1) virus of the Eurasian avian lineage occurred in a child with a previous history of eczema in the Netherlands, following contact to pigs. The patient's condition deteriorated rapidly and required life support through extracorporeal membrane oxygenation. After start of oseltamivir treatment and removal of mucus plugs, the patient fully recovered. Monitoring of more than 80 close unprotected contacts revealed no secondary cases.
December 1, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27933712/the-importance-of-mrna-structure-in-determining-the-pathogenicity-of-synonymous-and-non-synonymous-mutations-in-haemophilia
#15
N Hamasaki-Katagiri, B C Lin, J Simon, R C Hunt, T Schiller, E Russek-Cohen, A A Komar, H Bar, C Kimchi-Sarfaty
INTRODUCTION: Mutational analysis is commonly used to support the diagnosis and management of haemophilia. This has allowed for the generation of large mutation databases which provide unparalleled insight into genotype-phenotype relationships. Haemophilia is associated with inversions, deletions, insertions, nonsense and missense mutations. Both synonymous and non-synonymous mutations influence the base pairing of messenger RNA (mRNA), which can alter mRNA structure, cellular half-life and ribosome processivity/elongation...
December 9, 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/27933262/software-project-management-tools-in-global-software-development-a-systematic-mapping-study
#16
Saad Yasser Chadli, Ali Idri, Joaquín Nicolás Ros, José Luis Fernández-Alemán, Juan M Carrillo de Gea, Ambrosio Toval
Global software development (GSD) which is a growing trend in the software industry is characterized by a highly distributed environment. Performing software project management (SPM) in such conditions implies the need to overcome new limitations resulting from cultural, temporal and geographic separation. The aim of this research is to discover and classify the various tools mentioned in literature that provide GSD project managers with support and to identify in what way they support group interaction. A systematic mapping study has been performed by means of automatic searches in five sources...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27932687/diabetes-distress-among-persons-with-type-1-diabetes-associations-with-disordered-eating-depression-and-other-psychological-health-concerns
#17
Margaret A Powers, Sara A Richter, Diann M Ackard, Cheryl Craft
PURPOSE: The purpose of this study is to evaluate associations between diabetes distress and a range of psychological health behaviors and concerns among persons with type 1 diabetes for the benefit of enhancing early identification and intervention of at-risk individuals. METHODS: Persons with type 1 diabetes (n = 268; 57.1% female, 91.0% white, 76.8% <18 years of age, average A1C 8.4%) completed the 2-item Diabetes Distress Screening Scale (DDS2) and a battery of psychometrically sound instruments measuring satisfaction with life, self-esteem, self-efficacy, depression, perfectionism, body image satisfaction, dietary restraint and eating, and shape and weight concerns...
December 7, 2016: Diabetes Educator
https://www.readbyqxmd.com/read/27932543/members-of-the-zinc-cluster-factor-family-alters-virulence-in-candida-albicans
#18
Luca Issi, Rhys A Farrer, Kelly Pastor, Benjamin Landry, Toni Delorey, George W Bell, Dawn A Thompson, Christina A Cuomo, Reeta P Rao
Virtually all humans are colonized with Candida albicans However, in immunocompromised individuals this benign commensal organism becomes a serious, life-threatening pathogen. Here, we describe and analyze the regulatory networks that modulate innate responses in the host niches. We identified Zcf15 and Zcf29, two Zinc Cluster transcription Factors (ZCF) that are required for C. albicans virulence. Previous sequence analysis of clinical C. albicans isolates from immunocompromised patients indicates that both ZCF genes diverged during clonal evolution...
December 7, 2016: Genetics
https://www.readbyqxmd.com/read/27932533/preoperative-proteinuria-and-reduced-glomerular-filtration-rate-predicts-renal-replacement-therapy-in-patients-supported-with-continuous-flow-left-ventricular-assist-devices
#19
Veli K Topkara, Ellie J Coromilas, Arthur Reshad Garan, Randall C Li, Francesco Castagna, Douglas L Jennings, Melana Yuzefpolskaya, Koji Takeda, Hiroo Takayama, Robert N Sladen, Donna M Mancini, Yoshifumi Naka, Jai Radhakrishnan, Paolo C Colombo
BACKGROUND: Renal failure requiring renal replacement therapy (RRT) has detrimental effects on quality of life and survival of patients with continuous-flow left ventricular assist devices (CF-LVADs). Current guidelines do not offer a decision-making algorithm for CF-LVAD candidates with poor baseline renal function. Objective of this study was to identify risk factors associated with RRT after CF-LVAD implantation. METHODS AND RESULTS: Three hundred and eighty-nine consecutive patients underwent contemporary CF-LVAD implantation at the Columbia University Medical Center between January 2004 and August 2015...
December 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27932338/meaning-of-living-with-severe-chronic-obstructive-lung-disease-a-qualitative-study
#20
Gabriella Marx, Maximilian Nasse, Henrikje Stanze, Sonja Owusu Boakye, Friedemann Nauck, Nils Schneider
OBJECTIVES: To explore what it means for patients to live with chronic obstructive pulmonary disease (COPD) as an incurable and constantly progressing disease. DESIGN: Qualitative longitudinal study using narrative and semistructured interviews. This paper presents findings of the initial interviews. Analysis using grounded theory. SETTING: Lung care clinics and community care in Lower Saxony, Germany. PARTICIPANTS: 17 patients with advanced-stage COPD (Global Initiative for Chronic Obstructive Lung Disease (GOLD) III/IV)...
December 8, 2016: BMJ Open
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