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Sudden cardiac arrest

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https://www.readbyqxmd.com/read/29325976/profile-of-brugada-syndrome-patients-presenting-with-their-first-documented-arrhythmic-event-data-from-the-survey-on-arrhythmic-events-in-brugada-syndrome-sabrus
#1
Anat Milman, Antoine Andorin, Jean-Baptiste Gourraud, Pieter G Postema, Frederic Sacher, Philippe Mabo, Sung-Hwan Kim, Jimmy Jm Juang, Shingo Maeda, Yoshihide Takahashi, Tsukasa Kamakura, Takeshi Aiba, Giulio Conte, Georgia Sarquella-Brugada, Eran Leshem, Michael Rahkovich, Aviram Hochstadt, Yuka Mizusawa, Elena Arbelo, Zhengrong Huang, Isabelle Denjoy, Carla Giustetto, Yanushi D Wijeyeratne, Carlo Napolitano, Yoav Michowitz, Ramon Brugada, Ruben Casado-Arroyo, Jean Champagne, Leonardo Calo, Jacob Tfelt-Hansen, Silvia G Priori, Masahiko Takagi, Christian Veltmann, Pietro Delise, Domenico Corrado, Elijah R Behr, Fiorenzo Gaita, Gan-Xin Yan, Josep Brugada, Antoine Leenhardt, Arthur A M Wilde, Pedro Brugada, Kengo F Kusano, Kenzo Hirao, Gi-Byoung Nam, Vincent Probst, Bernard Belhassen
BACKGROUND: Detailed information on the profile of Brugada syndrome (BrS) patients presenting their first arrhythmic event (AE) after prophylactic implantation of a cardioverter defibrillator (ICD) is limited. OBJECTIVES: 1) To compare clinical, electrocardiographic, electrophysiologic and genetic profiles of patients who exhibited their first documented AE as aborted cardiac arrest (CA) (group A) with those in whom the AE was documented after prophylactic ICD implantation (group B); 2) To characterize group B patients' profile using the Class II indications for ICD implantation established by HRS/EHRA/APHRS Expert Consensus Statement in 2013...
January 8, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29324812/identifying-unmet-clinical-need-in-hypertrophic-cardiomyopathy-using-national-electronic-health-records
#2
Mar Pujades-Rodriguez, Oliver P Guttmann, Arturo Gonzalez-Izquierdo, Bram Duyx, Constantinos O'Mahony, Perry Elliott, Harry Hemingway
INTRODUCTION: To evaluate unmet clinical need in unselected hypertrophic cardiomyopathy (HCM) patients to determine the risk of a wide range of subsequent cardiovascular disease endpoints and safety endpoints relevant for trial design. METHODS: Population based cohort (CALIBER, linked primary care, hospital and mortality records in England, period 1997-2010), all people diagnosed with HCM were identified and matched by age, sex and general practice with ten randomly selected people without HCM...
2018: PloS One
https://www.readbyqxmd.com/read/29318626/trends-and-predictors-of-implantable-cardioverter-defibrillator-implantation-after-sudden-cardiac-arrest-insight-from-the-national-inpatient-sample
#3
Muhammad Bilal Munir, Fahad Alqahtani, Sami Aljohani, Ashwin Bhirud, Sujal Modi, Mohamad Alkhouli
BACKGROUND: Implantable cardioverter defibrillator (ICD) has a class IA indication in survivors of sudden cardiac arrest (SCA) provided no reversible cause is identified. We sought to determine trends and predictors of ICD implant in SCA patients from a national sample of United States population. METHODS AND RESULTS: Data was gathered from National Inpatient Sample (NIS) from January 2003 to December 2014. All patients ≥ 18 years of age with a primary discharge diagnosis of SCA, ventricular fibrillation (VF), ventricular flutter, and ventricular tachycardia (VT) were included...
January 9, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29317976/postpartum-sudden-cardiac-death-after-spontaneous-coronary-artery-dissection-in-a-patient-with-fibromuscular-dysplasia
#4
Tannaz Shoja, Craig Basman, Suresh Jain, Aditya Mangla, Zoran Lasic
Spontaneous coronary artery dissection (SCAD) is a rare entity that can cause acute myocardial infarction and sudden cardiac death (SCD) which often goes unrecognized. We report a case of SCAD in a young postpartum female who presented with sudden cardiac arrest. The patient was managed medically and found to have fibromuscular dysplasia (FMD). After being stabilized in the critical care unit, coronary angiography was performed which showed dissection of the left main artery, intramural hematoma, and the culprit lesion...
December 2017: Cardiology Research
https://www.readbyqxmd.com/read/29317589/successful-treatment-in-a-patient-with-sudden-cardiac-arrest-due-to-anomalous-left-coronary-artery-arising-from-pulmonary-artery
#5
Liping Zhou, Xiaogang Li, Min Qi, Aimin Wang
To enhance the understanding of the left coronary artery originating from the pulmonary artery, we report a case of sudden cardiac arrest during exercise. After successful cardiopulmonary resuscitation, the patient underwent echocardiography and selective coronary angiography, and the disease was firmly diagnosed. Consequently, a thoracic surgery was performed. During the operation, the left coronary artery was transplanted to the root of the aorta and the pulmonary valve and artery were reconstructed. Finally, the surgery was successful...
December 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29312750/mitral-valve-prolapse-an-underestimated-cause-of-sudden-cardiac-death-a-current-review-of-the-literature
#6
REVIEW
Michael Spartalis, Eleni Tzatzaki, Eleftherios Spartalis, Antonios Athanasiou, Demetrios Moris, Christos Damaskos, Nikolaos Garmpis, Vassilis Voudris
Mitral valve prolapse (MVP) is a common valve abnormality in general population. Despite the general belief of a benign disorder, several articles since the 1980s report sudden cardiac death (SCD) in MVP patients, with a substantial percentage of asymptomatic young individuals. The problem is to detect those patients at increased risk and implement methods that are suitable to prevent cardiac arrest. This review investigates the correlation between MVP and SCD, the understanding of the pathophysiology, the strategies for detecting those at risk and treatment options...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29310415/cisplatin-induced-sudden-cardiac-death-with-hemodynamic-collapse-a-severe-adverse-drug-reaction-case-report
#7
Silvijus Abramavicius, Marius Zemaitis, Vidas Pilvinis, Edmundas Kadusevicius
RATIONALE: Cisplatin is responsible for a significant percentage of adverse drug reactions (ADRs) in oncology setting. A great proportion of cisplatin-induced severe adverse events are difficult to foresee, and giving premedication does not always prevent the occurrence of such events. PATIENT CONCERNS: A 53-year-old woman with progressive T4 N0 M0 stage IV pleural mesothelioma experienced cardiac arrest with hemodynamic collapse after cisplatin and pemetrexed chemotherapy administration...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29309564/role-of-syncope-in-predicting-adverse-outcomes-in-patients-with-suspected-brugada-syndrome-undergoing-standardized-flecainide-testing
#8
Juan Pablo Flórez, Daniel García, Irene Valverde, José Rubín, Diego Pérez, Mar González-Vasserot, Julián Reguero, Jesús María de la Hera, Pablo Avanzas, Juan Gómez, Eliecer Coto, César Morís, David Calvo
Aims: Sensitivity to flecainide testing results in suboptimal findings in patients with Brugada syndrome (BrS), leading to safety concerns. Because cardiac syncope effectively predicts outcomes in BrS, we aimed to explore its predictive value in a large cohort of negative and positive responders (NR and PR) to standard flecainide testing. Methods and results : We analysed the data of 251 consecutive patients, 177 NR vs. 74 PR, to flecainide testing, performed according to standard recommendations...
December 22, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29302124/extracorporeal-life-support-as-a-rescue-measure-for-managing-life-threatening-arrythmia-and-brugada-syndrome
#9
Asaad G Beshish, Allison Weinberg, Waseem Ostwani, Gabe E Owens
We describe the use of extracorporeal cardiopulmonary resuscitation (E-CPR) to transiently stabilize a 3-month-old patient who presented with ventricular tachyarrhythmias leading to spontaneous cardiac arrest. The patient required 4 days of extracorporeal life support (ECLS) where he was diagnosed with probable Brugada syndrome (BS). The patient was discharged home in stable condition after implantable cardioverter defibrillator placement. This case highlights the importance of early transfer to extracorporeal membrane oxygenation (ECMO) center in the setting of unexplained cardiac arrhythmia in a pediatric patient...
December 2017: Journal of Extra-corporeal Technology
https://www.readbyqxmd.com/read/29301706/an-experimental-study-and-finite-element-modeling-of-head-and-neck-cooling-for-brain-hypothermia
#10
Hui Li, Roland K Chen, Yong Tang, William Meurer, Albert J Shih
Reducing brain temperature by head and neck cooling is likely to be the protective treatment for humans when subjects to sudden cardiac arrest. This study develops the experimental validation model and finite element modeling (FEM) to study the head and neck cooling separately, which can induce therapeutic hypothermia focused on the brain. Anatomically accurate geometries based on CT images of the skull and carotid artery are utilized to find the 3D geometry for FEM to analyze the temperature distributions and 3D-printing to build the physical model for experiment...
January 2018: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29249614/extracorporeal-cardiopulmonary-resuscitation-for-refractory-out-of-hospital-cardiac-arrest-the-state-of-the-evidence-and-framework-for-application
#11
REVIEW
Brian Grunau, Laura Hornby, Rohit K Singal, Jim Christenson, Ivan Ortega-Deballon, Sam D Shemie, Jamil Bashir, Steve C Brooks, Clifton W Callaway, Elena Guadagno, Dave Nagpal
Out-of-hospital cardiac arrest (OHCA) affects 134 per 100,000 citizens annually. Extracorporeal cardiopulmonary resuscitation (ECPR), providing mechanical circulatory support, may improve the likelihood of survival among those with refractory OHCA. Compared with in-hospital ECPR candidates, those in the out-of-hospital setting tend to be sudden unexpected arrests in younger and healthier patients. The aims of this review were to summarize, and identify the limitations of, the evidence evaluating ECPR for OHCA, and to provide an approach for ECPR program application...
September 9, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29246744/determinants-of-occurrence-and-survival-after-sudden-cardiac-arrest-a-european-perspective-the-escape-net-project
#12
Jean-Philippe Empana, Marieke T Blom, Bernd W Bӧttiger, Nikolaos Dagres, Jacqueline M Dekker, Gunnar Gislason, Xavier Jouven, Thomas Meitinger, Giuseppe Ristagno, Peter J Schwartz, Martin Jonsson, Jacob Tfelt-Hansen, Anatolij Truhlar, Hanno L Tan
AIMS: The ESCAPE-NET project ("European Sudden Cardiac Arrest network - towards Prevention, Education and New Effective Treatments") aims to study: (1) risk factors and mechanisms for the occurrence of sudden cardiac arrest (SCA) in the population, and (2) risk factors and treatment strategies for survival after SCA on a European scale. METHODS: This is an Horizon2020 funded program of the European Union, performed by a European public-private consortium of 16 partners across 10EU countries...
December 12, 2017: Resuscitation
https://www.readbyqxmd.com/read/29246546/surgical-unroofing-of-intramural-anomalous-aortic-origin-of-a-coronary-artery-in-pediatric-patients-single-center-perspective
#13
Shagun Sachdeva, Michele A Frommelt, Michael E Mitchell, James S Tweddell, Peter C Frommelt
BACKGROUND: Intramural anomalous aortic origin of a coronary artery (AAOCA) is associated with an increased risk of sudden cardiac death. This is amenable to surgical coronary unroofing, but outcomes studies are lacking. OBJECTIVE: To perform a comprehensive review of our institutional experience with pediatric patients with AAOCA who underwent surgical repair with unroofing of the intramural segment, focusing on preoperative and postoperative course and testing as well as intraoperative findings...
November 10, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29241489/hydroquinidine-prevents-life-threatening-arrhythmic-events-in-patients-with-short%C3%A2-qt%C3%A2-syndrome
#14
Andrea Mazzanti, Riccardo Maragna, Gaetano Vacanti, Anna Kostopoulou, Maira Marino, Nicola Monteforte, Raffaella Bloise, Katherine Underwood, Valentina Tibollo, Eleonora Pagan, Carlo Napolitano, Riccardo Bellazzi, Vincenzo Bagnardi, Silvia G Priori
BACKGROUND: Short QT syndrome (SQTS) is a rare and life-threatening arrhythmogenic syndrome characterized by abbreviated repolarization. Hydroquinidine (HQ) prolongs the QT interval in SQTS patients, although whether it reduces cardiac events is currently unknown. OBJECTIVES: This study investigated whether long-term treatment with HQ reduces the occurrence of life-threatening arrhythmic events (LAE) (cardiac arrest or sudden cardiac death) in SQTS patients. METHODS: In this cohort study on consecutive SQTS patients, 2 analyses were performed: 1) a matched-period analysis for the occurrence of LAE in 17 SQTS patients who received long-term HQ; and 2) a comparison of the annual incidence of LAE off- and on-HQ in 16 SQTS patients who survived a cardiac arrest...
December 19, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29237610/cardiac-magnetic-resonance-in-sudden-cardiac-arrest-survivors
#15
EDITORIAL
Wojciech Zareba, Karolina M Zareba
No abstract text is available yet for this article.
December 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29237609/diagnosis-and-prognosis-in-sudden-cardiac-arrest-survivors-without-coronary-artery-disease-utility-of-a-clinical-approach-using-cardiac-magnetic-resonance-imaging
#16
Patricia Rodrigues, Abhishek Joshi, Howell Williams, Mark Westwood, Steffen E Petersen, Filip Zemrak, Richard J Schilling, Claire Kirkby, Andrew Wragg, Charlotte Manisty, Saidi Mohiddin
BACKGROUND: Determining the pathogenesis of sudden cardiac arrest or periarrest without significant coronary artery disease is crucial for management and prognosis. Cardiovascular magnetic resonance (CMR) can detect morphological, functional, or tissue abnormalities, and we sought to evaluate the role of CMR in determining sudden cardiac arrest pathogenesis and prognosis in survivors. METHODS AND RESULTS: We retrospectively reviewed cardiac investigations and clinical outcomes in consecutive survivors of potentially fatal arrhythmias without coronary artery disease admitted to our institutions from 2008 to 2014...
December 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29237243/exercise-related-severe-cardiac-events
#17
Lourdes Vicent, Albert Ariza-Solé, José Ramón González-Juanatey, Aitor Uribarri, José Ortiz, Esteban López de Sá, Jordi Sans-Roselló, Carlos Tomás Querol, Pau Codina, Iago Sousa-Casasnovas, Manuel Martínez-Sellés
BACKGROUND: Physical activity has benefits on health. However, there is a small risk of effort-related adverse events. The aim of this study is to describe exercise-related severe cardiovascular events and to relate them with the type of sport performed. METHODS: Ten-year retrospective study in 8 Spanish cardiac intensive care units. Adverse cardiac events were defined as acute myocardial infarction, cardiac arrest, or syncope related to physical activity. RESULTS: From 117 patients included, 109 were male (93...
December 13, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29236216/long-term-outcomes-of-a%C3%A2-caucasian-cohort-presenting-with-acute-coronary-syndrome-and-or-out-of-hospital-cardiac-arrest-caused-by-coronary-spasm
#18
W Vlastra, M Piek, M A van Lavieren, M E J C Hassell, B E Claessen, G W Wijntjens, T P van de Hoef, K D Sjauw, M A Beijk, R Delewi, J J Piek
BACKGROUND: Coronary artery spasm may be the underlying mechanism in up to 10% of cases of acute coronary syndrome (ACS) and sudden cardiac death. Asian individuals exhibit a 3-times greater incidence of spasm than Caucasians; this is likely due to different types of mechanisms. Consequently, solid data is limited about the long-term prognosis in Caucasian patients presenting with ACS and/or out-of-hospital cardiac arrest (OHCA) caused by coronary spasm. METHODS: Between 2002 and 2015, thirty Caucasian patients with coronary artery spasm presenting with ACS (N = 29) and/or OHCA (N = 11) were enrolled in this prospective registry...
December 13, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/29225848/delayed-diagnosis-of-brugada-syndrome-in-a-patient-with-aborted-sudden-cardiac-death-and-initial-negative-flecainide-challenge
#19
Samuel Chauveau, Olivier Le Vavasseur, Philippe Chevalier
A negative flecainide challenge does not rule out Brugada syndrome even in the presence of nonfatal cardiac arrest as the first manifestation of the disease. This should prompt clinicians to ensure long-term ECG follow-up and consider repeating a drug test with another sodium channel blocker.
December 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29215340/a-report-of-brugada-syndrome-presenting-with-cardiac-arrest-triggered-by-verapamil-intoxication
#20
Kahraman Yakut, İlkay Erdoğan, Birgül Varan, İlyas Atar
BACKGROUND: Brugada syndrome is a disease characterized by a specific electrocardiographic pattern and an increased risk of sudden cardiac death. We present this case with the updated literature to emphasise the need to consider the diagnosis of Brugada syndrome in patients admitted to the emergency ward with sudden cardiac arrest. CASE REPORT: A 16-year-old female patient was admitted to the emergency ward with complaints of weakness and abdominal pain, and she had four cardiac arrests during her evaluation period...
December 1, 2017: Balkan Medical Journal
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