keyword
MENU ▼
Read by QxMD icon Read
search

"Pain+cognition"

keyword
https://www.readbyqxmd.com/read/29753795/non-anesthetic-effects-of-ketamine-a-review-article-authors-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2
#1
REVIEW
Jabril Eldufani, Alireza Nekoui, Gilbert Blaise
Ketamine is considered a dissociative anesthetic medication, and it is a commonly administered by a parenteral route. It works mainly by blocking the N-methyl-D-aspartate (NMDA) receptor. It inhibits the voltage-gated Na_ and K_ channels and serotonin and dopamine re-uptake; also, it affects specific receptors, such as α-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid (AMPA), kainate and aminobutyric acid A receptors. Ketamine appears to have particular mechanisms that are potentially involved during analgesic induction, including enhancing of descending inhibition and anti-inflammatory effects...
May 10, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29713475/exercise-for-toxicity-management-in-cancer-a-narrative-review
#2
Ian R Kleckner, Richard F Dunne, Matthew Asare, Calvin Cole, Fergal Fleming, Chunkit Fung, Po-Ju Lin, Karen M Mustian
Although the treatment of cancer is more effective now than ever, patients with cancer still face acute and chronic toxicities such as fatigue, cardiotoxicity, pain, cognitive impairment, and neurotoxicity. In this narrative review, we briefly discuss the use of exercise for toxicity management in patients with cancer, biological mechanisms underlying the toxicities and the effects of exercise, barriers that patients- especially underserved patients-face in adopting and adhering to exercise programs, and new technologies to overcome barriers to exercise...
2018: Oncology & Hematology Review
https://www.readbyqxmd.com/read/29710099/effect-of-pain-neuroscience-education-combined-with-cognition-targeted-motor-control-training-on-chronic-spinal-pain-a-randomized-clinical-trial
#3
Anneleen Malfliet, Jeroen Kregel, Iris Coppieters, Robby De Pauw, Mira Meeus, Nathalie Roussel, Barbara Cagnie, Lieven Danneels, Jo Nijs
Importance: Effective treatments for chronic spinal pain are essential to reduce the related high personal and socioeconomic costs. Objective: To compare pain neuroscience education combined with cognition-targeted motor control training with current best-evidence physiotherapy for reducing pain and improving functionality, gray matter morphologic features, and pain cognitions in individuals with chronic spinal pain. Design, Setting, and Participants: Multicenter randomized clinical trial conducted from January 1, 2014, to January 30, 2017, among 120 patients with chronic nonspecific spinal pain in 2 outpatient hospitals with follow-up at 3, 6, and 12 months...
April 16, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29604314/zebrafish-models-relevant-to-studying-central-opioid-and-endocannabinoid-systems
#4
REVIEW
Konstantin A Demin, Darya A Meshalkina, Elana V Kysil, Kristina A Antonova, Andrey D Volgin, Oleg A Yakovlev, Polina A Alekseeva, Maria M Firuleva, Anton M Lakstygal, Murilo S de Abreu, Leonardo J G Barcellos, Wandong Bao, Ashton J Friend, Tamara G Amstislavskaya, Denis B Rosemberg, Pavel E Musienko, Cai Song, Allan V Kalueff
The endocannabinoid and opioid systems are two interplaying neurotransmitter systems that modulate drug abuse, anxiety, pain, cognition, neurogenesis and immune activity. Although they are involved in such critical functions, our understanding of endocannabinoid and opioid physiology remains limited, necessitating further studies, novel models and new model organisms. Zebrafish (Danio rerio) is rapidly emerging as one of the most effective translational models in neuroscience and biological psychiatry. Due to their high physiological and genetic homology to humans, zebrafish may be effectively used to study the endocannabinoid and opioid systems...
March 28, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29589874/genome-editing-in-neuroepithelial-stem-cells-to-generate-human-neurons-with-high-adenosine-releasing-capacity
#5
Daniel Poppe, Jonas Doerr, Marion Schneider, Ruven Wilkens, Julius A Steinbeck, Julia Ladewig, Allison Tam, David E Paschon, Philip D Gregory, Andreas Reik, Christa E Müller, Philipp Koch, Oliver Brüstle
As a powerful regulator of cellular homeostasis and metabolism, adenosine is involved in diverse neurological processes including pain, cognition, and memory. Altered adenosine homeostasis has also been associated with several diseases such as depression, schizophrenia, or epilepsy. Based on its protective properties, adenosine has been considered as a potential therapeutic agent for various brain disorders. Since systemic application of adenosine is hampered by serious side effects such as vasodilatation and cardiac suppression, recent studies aim at improving local delivery by depots, pumps, or cell-based applications...
March 28, 2018: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29573870/what-low-back-pain-is-and-why-we-need-to-pay-attention
#6
REVIEW
Jan Hartvigsen, Mark J Hancock, Alice Kongsted, Quinette Louw, Manuela L Ferreira, Stéphane Genevay, Damian Hoy, Jaro Karppinen, Glenn Pransky, Joachim Sieper, Rob J Smeets, Martin Underwood
Low back pain is a very common symptom. It occurs in high-income, middle-income, and low-income countries and all age groups from children to the elderly population. Globally, years lived with disability caused by low back pain increased by 54% between 1990 and 2015, mainly because of population increase and ageing, with the biggest increase seen in low-income and middle-income countries. Low back pain is now the leading cause of disability worldwide. For nearly all people with low back pain, it is not possible to identify a specific nociceptive cause...
March 20, 2018: Lancet
https://www.readbyqxmd.com/read/29520913/delineation-between-different-components-of-chronic-pain-using-dimension-reduction-an-asl-fmri-study-in-hand-osteoarthritis
#7
D Keszthelyi, Q Aziz, J K Ruffle, O O'Daly, D Sanders, K Krause, S C R Williams, M A Howard
BACKGROUND: Traditional psychometric measures aimed at characterizing the pain experience often show considerable overlap, due to interlinked affective and modulatory processes under central nervous system control. Neuroimaging studies have been employed to investigate this complexity of pain processing, in an attempt to provide a quantifiable, adjunctive description of pain perception. In this exploratory study, we examine psychometric and neuroimaging data from 38 patients with painful osteoarthritis of the carpometacarpal joint...
March 9, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29511822/-restricted-mobility-in-nursing-home-residents-the-role-of-pain-and-cognitive-capacity
#8
REVIEW
N Nestler, L Krisch, A Mahlknecht, M Flamm, J Osterbrink
BACKGROUND: Pain, restriction of mobility and cognitive impairment are often present in old age and intensify each other. OBJECTIVES: Is there a relationship between mobility, pain, cognitive capacity, diagnoses and number of prescribed medication for residents of nursing homes? METHODS: Subgroup analysis of the baseline data from an intervention study for optimization of the medication safety of 120 nursing home residents. RESULTS: Pain was presumed in 77...
March 6, 2018: Der Schmerz
https://www.readbyqxmd.com/read/29501360/depression-and-coping-behaviors-are-key-factors-in-understanding-pain-in-interstitial-cystitis-bladder-pain-syndrome
#9
Abi Muere, Dean A Tripp, J Curtis Nickel, Kerri-Lynn Kelly, Robert Mayer, Michel Pontari, Robert Moldwin, Lesley K Carr, Claire C Yang, Jorgen Nordling
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a urologic chronic pelvic pain syndrome with suboptimal treatment outcomes. Catastrophizing is an empirically supported risk factor for greater IC/BPS pain. In this study, a moderated multiple mediation model is tested in which several additional psychosocial risk factors (depression, illness and wellness-focused behavioral coping strategies) are proposed as mediators or moderators in the existing relationship between catastrophizing and IC/BPS pain. The present questionnaire study employed a cross-sectional design...
February 28, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29440208/meta-analysis-of-self-reported-health-symptoms-in-1990-1991-gulf-war-and-gulf-war-era-veterans
#10
Alexis L Maule, Patricia A Janulewicz, Kimberly A Sullivan, Maxine H Krengel, Megan K Yee, Michael McClean, Roberta F White
OBJECTIVES: Across diverse groups of Gulf War (GW) veterans, reports of musculoskeletal pain, cognitive dysfunction, unexplained fatigue, chronic diarrhoea, rashes and respiratory problems are common. GW illness is a condition resulting from GW service in veterans who report a combination of these symptoms. This study integrated the GW literature using meta-analytical methods to characterise the most frequently reported symptoms occurring among veterans who deployed to the 1990-1991 GW and to better understand the magnitude of ill health among GW-deployed veterans compared with non-deployed GW-era veterans...
February 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29425327/sleep-disturbances-in-chronic-pain-neurobiology-assessment-and-treatment-in-physical-therapist-practice
#11
Jo Nijs, Olivier Mairesse, Daniel Neu, Laurence Leysen, Lieven Danneels, Barbara Cagnie, Mira Meeus, Maarten Moens, Kelly Ickmans, Dorien Goubert
Among people with chronic pain, insomnia is highly prevalent, closely related to the mechanism of central sensitization, characterized by low-grade neuroinflammation, and commonly associated with stress or anxiety; in addition, it often does not respond effectively to drug treatments. This review article applies the current understanding of insomnia to clinical practice, including assessment and conservative treatment of insomnia in people with chronic pain. Cognitive-behavioral therapy for insomnia can be efficacious for improvements in sleep initiation, sleep maintenance, perceived sleep quality, and pain interference with daily functioning in people with chronic pain...
May 1, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29419654/interventions-for-attentional-disruption-in-pain-cognition-general-mechanism-specific-or-exercise-based
#12
Nina Attridge, Nils Georg Niederstrasser
No abstract text is available yet for this article.
April 2018: Pain
https://www.readbyqxmd.com/read/29222851/convergent-validity-of-the-dutch-central-sensitization-inventory-associations-with-psychophysical-pain-measures-quality-of-life-disability-and-pain-cognitions-in-patients-with-chronic-spinal-pain
#13
Jeroen Kregel, Charline Schumacher, Mieke Dolphens, Anneleen Malfliet, Dorien Goubert, Dorine Lenoir, Barbara Cagnie, Mira Meeus, Iris Coppieters
OBJECTIVE: Symptoms of central sensitization (CS) have been described in patients with chronic spinal pain (CSP). Although a gold standard to diagnose CS is lacking, psychophysical pain measures are often used. The Central Sensitization Inventory (CSI) is proposed as an alternative method and indirect tool for the evaluation of CS symptomatology. The aim of the current study was to evaluate the convergent validity of the CSI by investigating the association with psychophysical pain measures and self-reported measures of current pain intensity, quality of life, disability, and catastrophizing in CSP patients...
December 8, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29189216/factors-contributing-to-memory-of-acute-pain-in-older-adults-undergoing-planned-and-unplanned-hip-surgery
#14
Monika Halicka, Przemysław Bąbel
OBJECTIVES: Previous research on pain memory provides inconsistent evidence about the accuracy of pain recall, and few studies have attempted to examine broad affective and contextual contributions to this phenomenon. The present research aimed to determine the accuracy of postoperative pain recall after a 3-months, with respect to the context of the surgery and the congruence of affective states concurrent with the initial experience and its recall. The study also aimed to identify predictors of remembered pain by analysing a range of sensory, cognitive and affective factors...
November 17, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29186680/astrocytic-l-lactate-signaling-facilitates-amygdala-anterior-cingulate-cortex-synchrony-and-decision-making-in-rats
#15
Jun Wang, Jie Tu, Bing Cao, Li Mu, Xiangwei Yang, Mi Cong, Aruna S Ramkrishnan, Rosa H M Chan, Liping Wang, Ying Li
Human brain imaging studies have revealed the anterior cingulate cortex (ACC) as a key brain region for mediating visceral-pain-cognitive interactions. Recently, we characterized impairments of long-term potentiation and spike-field coherence in the basolateral amygdala (BLA)-ACC network in association with a decision-making deficit in rats with visceral hypersensitivity (VH). Now, by combining integrative neurobiological approaches, we show that ACC-reactive astrogliosis and activity-dependent impairment of lactate release occur in VH rats...
November 28, 2017: Cell Reports
https://www.readbyqxmd.com/read/29149149/decreased-regional-grey-matter-volume-in-women-with-chronic-whiplash-associated-disorders-relationships-with-cognitive-deficits-and-disturbed-pain-processing
#16
Iris Coppieters, Robby De Pauw, Karen Caeyenberghs, Lieven Danneels, Jeroen Kregel, Astrid Pattyn, Mira Meeus, Barbara Cagnie
BACKGROUND: Patients with chronic whiplash-associated disorders (CWAD) are characterized by pain of traumatic origin, cognitive deficits, and central sensitization (CS). Previous neuroimaging studies revealed altered grey matter volume (GMV) in mild traumatic brain injury patients and chronic pain conditions also characterized by CS. It can therefore be hypothesized that GMV alterations also play a role in the persistent complaints of CWAD. However, brain alterations remain poorly investigated in these patients...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29053973/duration-of-moderate-to-vigorous-daily-activity-is-negatively-associated-with-slow-walking-speed-independently-from-step-counts-in-elderly-women-aged-75-years-or-over-a-cross-sectional-study
#17
Takuji Adachi, Yuji Kono, Kotaro Iwatsu, Yuko Shimizu, Sumio Yamada
OBJECTIVES: This study aimed 1) to examine whether objectively measured duration of moderate to vigorous physical activity (MVPA) was associated with slow walking speed, independent from step counts, in elderly women aged 75 or over (old-old) and 2) to determine a possible cut-off value for duration of MVPA related to slow walking speed. METHODS: Participants were 350 community-dwelling old-old women. Slow walking speed was defined as usual walking speed <1.0m/s...
January 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28911933/pain-cognition-versus-pain-intensity-in-patients-with-endometriosis-toward-personalized-treatment
#18
Mieke A W van Aken, Joukje M Oosterman, C M van Rijn, Magdalena A Ferdek, Gé S F Ruigt, B W M M Peeters, Didi D M Braat, Annemiek W Nap
OBJECTIVE: To explore how pain intensity and pain cognition are related to health-related quality of life (HRQoL) in women with endometriosis. DESIGN: Cross-sectional questionnaire-based survey. SETTING: Multidisciplinary referral center. PATIENT(S): Women with laparoscopically and/or magnetic resonance imaging-proven endometriosis (n = 50) and healthy control women (n = 42). INTERVENTION(S): For HRQoL, two questionnaires: the generic Short Form Health Survey (SF-36) and the Endometriosis Health Profile 30 (EHP-30)...
October 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28845408/pain-in-the-context-of-family-a-study-on-factors-contributing-to-marital-satisfaction-among-couples-suffering-from-chronic-pain
#19
Fatemeh Akbari, Mohsen Dehghani
BACKGROUND: Chronic pain is associated with increased stress in families and has its own impact on the relationship between members of the family. Among couples, if one of them suffers from chronic pain, this may influence marital satisfaction in both of them and given the importance of marital satisfaction in the prediction of successful treatment outcome, it is important to investigate pain and personality-related factors contributing to inter-individuals variation in marital satisfaction...
July 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28794875/the-humtick-study-protocol-for-a-prospective-cohort-study-on-post-treatment-lyme-disease-syndrome-and-the-disease-and-cost-burden-of-lyme-borreliosis-in-belgium
#20
Laurence Geebelen, Tinne Lernout, Benoît Kabamba-Mukadi, Veroniek Saegeman, Hein Sprong, Steven Van Gucht, Philippe Beutels, Niko Speybroeck, Katrien Tersago
BACKGROUND: In Belgium, different routine surveillance systems are in place to follow-up Lyme borreliosis trends. However, accurate data on the disease and monetary burden for the different clinical manifestations are lacking. Despite recommended antibiotic treatment, a proportion of Lyme patients report persisting aspecific symptoms for six months or more (e.g. fatigue, widespread musculoskeletal pain, cognitive difficulties), a syndrome now named "post-treatment Lyme disease syndrome" (PTLDS)...
2017: Archives of Public Health, Archives Belges de Santé Publique
keyword
keyword
78249
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"