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https://www.readbyqxmd.com/read/28289812/the-icm-research-agenda-on-intensive-care-unit-acquired-weakness
#1
Nicola Latronico, Margaret Herridge, Ramona O Hopkins, Derek Angus, Nicholas Hart, Greet Hermans, Theodore Iwashyna, Yaseen Arabi, Giuseppe Citerio, E Wesley Ely, Jesse Hall, Sangeeta Mehta, Kathleen Puntillo, Johannes Van den Hoeven, Hannah Wunsch, Deborah Cook, Claudia Dos Santos, Gordon Rubenfeld, Jean-Louis Vincent, Greet Van den Berghe, Elie Azoulay, Dale M Needham
We present areas of uncertainty concerning intensive care unit-acquired weakness (ICUAW) and identify areas for future research. Age, pre-ICU functional and cognitive state, concurrent illness, frailty, and health trajectories impact outcomes and should be assessed to stratify patients. In the ICU, early assessment of limb and diaphragm muscle strength and function using nonvolitional tests may be useful, but comparison with established methods of global and specific muscle strength and physical function and determination of their reliability and normal values would be important to advance these techniques...
March 13, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28240778/predictors-of-posttraumatic-stress-symptoms-and-association-with-fear-of-falling-after-hip-fracture
#2
Sara L Kornfield, Eric J Lenze, Kerri S Rawson
OBJECTIVES: To determine whether fall-related hip fracture, alone or in the presence of Fear of Falling, is likely to induce PTSD in an elderly population. DESIGN: A longitudinal prospective study of patients admitted for hip fracture. SETTING: Eight St. Louis, Missouri, area hospitals. PARTICIPANTS: Individuals aged 60 and older admitted for surgical hip fracture repair after a fall (N = 456). MEASUREMENTS: Rates of partial and full posttraumatic stress disorder (pPTSD and fPTSD) were compared with rates of FoF...
February 27, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28134037/destiny-rides-again-the-reappearance-of-silicone-gel-filled-breast-implant-toxicity
#3
A E Brawer
Background Twenty-five years ago attorneys representing ailing women in class action litigation against silicone breast implant manufacturers made the procedural error of defining silicone-induced toxicity in the courtroom before it was properly studied in the exam room. This aberrant methodology perverted the proper research process, rendered verification of any real disease elusive, and cemented the groundwork for a repeat public health crisis potentially affecting two million women in the USA who possess new silicone gel devices inserted over the past 10 years...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/27976933/treatment-of-pain-following-cancer-applying-neuro-immunology-in-rehabilitation-practice
#4
Jo Nijs, Laurence Leysen, Roselien Pas, Nele Adriaenssens, Mira Meeus, Wouter Hoelen, Kelly Ickmans, Niamh Moloney
AIM: Pain is the second most frequent persistent symptom following cancer treatment. This article aims at explaining how the implementation of contemporary pain neuroscience can benefit rehabilitation for adults following cancer treatment within an evidence-based perspective. MATERIALS AND METHODS: Narrative review. RESULTS: First, pain education is an effective but underused strategy for treating cancer related pain. Second, our neuro-immunological understanding of how stress can influence pain highlights the importance of integrating stress management into the rehabilitation approach for patients having cancer-related pain...
December 15, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27941097/a-comparative-study-of-cognitive-behavioural-therapy-and-shared-reading-for-chronic-pain
#5
Josie Billington, Grace Farrington, Sofia Lampropoulou, Jamie Lingwood, Andrew Jones, James Ledson, Kate McDonnell, Nicky Duirs, Anne-Louise Humphreys
The case for psychosocial interventions in relation to chronic pain, one of the most common health issues in contemporary healthcare, is well-established as a means of managing the emotional and psychological difficulties experienced by sufferers. Using mixed methods, this study compared a standard therapy for chronic pain, cognitive behavioural therapy (CBT), with a specific literature-based intervention, shared reading (SR) developed by national charity, The Reader. A 5-week CBT group and a 22-week SR group for patients with chronic pain ran in parallel, with CBT group members joining the SR group after the completion of CBT...
December 9, 2016: Medical Humanities
https://www.readbyqxmd.com/read/27891062/results-from-10-years-of-a-cbt-pain-self-management-outpatient-program-for-complex-chronic-conditions
#6
Kathryn A Boschen, Edward Robinson, Kent A Campbell, Sarah Muir, Elvina Oey, Kristen Janes, Samantha R Fashler, Joel Katz
Background. Traditional unimodal interventions may be insufficient for treating complex pain, as they do not address cognitive and behavioural contributors to pain. Cognitive Behavioural Therapy (CBT) and physical exercise (PE) are empirically supported treatments that can reduce pain and improve quality of life. Objectives. To examine the outcomes of a pain self-management outpatient program based on CBT and PE at a rehabilitation hospital in Toronto, Ontario. Methods. The pain management group (PMG) consisted of 20 sessions over 10 weeks...
2016: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/27867508/a-feasibility-study-to-determine-the-benefits-of-upper-extremity-virtual-rehabilitation-therapy-for-coping-with-chronic-pain-post-cancer-surgery
#7
Gregory House, Grigore Burdea, Namrata Grampurohit, Kevin Polistico, Doru Roll, Frank Damiani, Jasdeep Hundal, Didier Demesmin
BACKGROUND: Persistent pain in shoulder and arm following post-surgical breast cancer treatment can lead to cognitive and physical deficits. Depression is also common in breast cancer survivors. Virtual reality therapy with integrative cognitive and physical rehabilitation has not been clinically trialed for this population. The novel BrightArm Duo technology improved cognition and upper extremity (UE) function for other diagnoses and has great potential to benefit individuals coping with post-surgical breast cancer pain...
November 2016: British Journal of Pain
https://www.readbyqxmd.com/read/27867309/gender-differences-in-symptoms-health-related-quality-of-life-sleep-quality-mental-health-cognitive-performance-pain-cognition-and-positive-health-in-spanish-fibromyalgia-individuals-the-al-%C3%A3-ndalus-project
#8
Víctor Segura-Jiménez, Fernando Estévez-López, Alberto Soriano-Maldonado, Inmaculada C Álvarez-Gallardo, Manuel Delgado-Fernández, Jonatan R Ruiz, Virginia A Aparicio
Objective. To test the gender differences in tenderness, impact of fibromyalgia, health-related quality of life, fatigue, sleep quality, mental health, cognitive performance, pain-cognition, and positive health in Spanish fibromyalgia patients and in age-matched nonfibromyalgia individuals from the same region. To test the optimal cut-off score of the different tender points for women and men. Methods. A total of 405 (384 women) fibromyalgia versus 247 (195 women) nonfibromyalgia control participants from southern Spain (Andalusia) took part in this cross-sectional study...
2016: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/27853998/relations-between-adaptive-and-maladaptive-pain-cognitions-and-within-day-pain-exacerbations-in-individuals-with-fibromyalgia
#9
Shannon Stark Taylor, Mary C Davis, Ellen W Yeung, Alex J Zautra, Howard A Tennen
The objectives of this study were to assess within-person hypotheses regarding temporal cognition-pain associations: (1) do morning pain flares predict changes in two afternoon adaptive and maladaptive pain-related cognitions, and (2) do these changes in afternoon cognitions predict changes in end-of-day pain reports, which in turn, carry over to predict next morning pain in individuals with fibromyalgia. Two hundred twenty individuals with fibromyalgia completed electronic assessments of pain intensity, pain catastrophizing, and pain coping efficacy three times a day for three weeks...
November 16, 2016: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/27807031/distinct-regions-within-medial-prefrontal-cortex-process-pain-and-cognition
#10
Andrew Jahn, Derek Evan Nee, William H Alexander, Joshua W Brown
Neuroimaging studies of the medial prefrontal cortex (mPFC) suggest that the dorsal anterior cingulate cortex (dACC) region is responsive to a wide variety of stimuli and psychological states, such as pain, cognitive control, and prediction error (PE). In contrast, a recent meta-analysis argues that the dACC is selective for pain, whereas the supplementary motor area (SMA) and pre-SMA are specifically associated with higher-level cognitive processes (Lieberman and Eisenberger, 2015). To empirically test this claim, we manipulated effects of pain, conflict, and PE in a single experiment using human subjects...
December 7, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27742412/headache-impairs-attentional-performance-a%C3%A2-conceptual-replication-and-extension
#11
Nina Attridge, Christopher Eccleston, Donna Noonan, Elaine Wainwright, Edmund Keogh
Pain is thought to capture our attention. A consequence is that our performance on other tasks may suffer. Research has supported this, showing that pain disrupts our ability to perform various attention tasks. However, the specific nature of the effect of pain on attention is inconsistent, possibly due to different studies investigating different types of pain. Few studies seek to replicate basic findings. In this study, we conceptually replicated and extended the headache study by Moore, Keogh, and Eccleston in 2013, by including 2 additional attention tasks, a broader sample, and measures of affect and pain cognition...
January 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27738502/chronic-persistent-post-surgical-pain-following-staging-laparotomy-for-carcinoma-of-ovary-and-its-relationship-to-signal-transduction-genes
#12
Ashok Kumar Saxena, Geetanjali T Chilkoti, Anand K Chopra, Basu Dev Banerjee, Tusha Sharma
BACKGROUND: The present study was undertaken to evaluate the incidence of chronic persistent post-surgical pain (CPPP) and the role of signal transduction genes in patients undergoing staging laparotomy for carcinoma ovary. METHODS: The present observational study was undertaken following institutional ethical committee approval and informed consent from all the participants. A total 21 patients of ASA grade I to III with age 20-70 years, scheduled for elective staging laparotomy for carcinoma ovary were included...
October 2016: Korean Journal of Pain
https://www.readbyqxmd.com/read/27721367/a-pair-of-identical-twins-discordant-for-myalgic-encephalomyelitis-chronic-fatigue-syndrome-differ-in-physiological-parameters-and-gut-microbiome-composition
#13
Ludovic Giloteaux, Maureen R Hanson, Betsy A Keller
BACKGROUND Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) present with profound fatigue, flu-like symptoms, pain, cognitive impairment, orthostatic intolerance, and post-exertional malaise (PEM), and exacerbation of some or all of the baseline symptoms. CASE REPORT We report on a pair of 34-year-old monozygotic twins discordant for ME/CFS, with WELL, the non-affected twin, and ILL, the affected twin. Both twins performed a two-day cardiopulmonary exercise test (CPET), pre- and post-exercise blood samples were drawn, and both provided stool samples for biochemical and molecular analysis...
October 10, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27692388/high-frequency-of-asymptomatic-hyperparathyroidism-in-patients-with-fibromyalgia-random-association-or-misdiagnosis
#14
Juliana Maria de Freitas Trindade Costa, Aline Ranzolin, Cláudio Antônio da Costa Neto, Claudia Diniz Lopes Marques, Angela Luzia Branco Pinto Duarte
Fibromyalgia (FM) and hyperparathyroidism may present similar symptoms (musculoskeletal pain, cognitive disorders, insomnia, depression and anxiety), causing diagnostic confusion. OBJECTIVES: To determine the frequency of asymptomatic hyperparathyroidism in a sample of patients with FM and to evaluate the association of laboratory abnormalities to clinical symptoms. METHODS: Cross-sectional study with 100 women with FM and 57 healthy women (comparison group). Parathyroid hormone (PTH), calcium and albumin levels were accessed, as well as symptoms in the FM group...
September 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27689612/pain-cognition-and-quality-of-life-associate-with-structural-measures-of-brain-volume-loss-in-multiple-sclerosis
#15
Nora E Fritz, Snehashis Roy, Jennifer Keller, Jerry Prince, Peter A Calabresi, Kathleen M Zackowski
BACKGROUND: Multiple sclerosis (MS) is characterized by physical and mental impairments that often result in pain and reduced quality of life. OBJECTIVE: To understand the relationship of pain, quality of life, and cognition to structural measures of brain volume. METHODS: Behavioral measures were assessed in a single session using standardized questionnaires and rating scales. Brain volume measures were assessed with structural magnetic resonance imaging (MRI)...
October 14, 2016: NeuroRehabilitation
https://www.readbyqxmd.com/read/27676956/motor-cognitive-and-psychosocial-impacts-of-an-adapted-dance-program-among-children-with-charcot-marie-tooth-disease-an-exploratory-study
#16
Cherriere Claire, Melissa Martel, Sylvie Fortin, Marie-Joanie Raymond, Louis Nicolas Veilleux, Sylvie D'Arcy, Martin Lemay
OBJECTIVE: Charcot-Marie-Tooth disease (CMT) is a hereditary peripheral neuropathy and belongs to neuromuscular diseases. CMT affects motor function of children, but its clinical expressions are heterogeneous and it could also influence cognitive and psychosocial dimensions of patients. Physical activity is recommended for adults with CMT, but any study has been conducted with children. It is important to propose to children with CMT an adapted physical activity that enables a global approach of the patient...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27559737/reduced-maximal-force-during-acute-anterior-knee-pain-is-associated-with-deficits-in-voluntary-muscle-activation
#17
Sauro Salomoni, Kylie Tucker, François Hug, Megan McPhee, Paul Hodges
Although maximal voluntary contraction (MVC) force is reduced during pain, studies using interpolated twitch show no consistent reduction of voluntary muscle drive. The present study aimed to test if the reduction in MVC force during acute experimental pain could be explained by increased activation of antagonist muscles, weak voluntary activation at baseline, or changes in force direction. Twenty-two healthy volunteers performed maximal voluntary isometric knee extensions before, during, and after the effects of hypertonic (pain) and isotonic (control) saline injections into the infrapatellar fat pad...
2016: PloS One
https://www.readbyqxmd.com/read/27530770/depression-predicts-functional-outcome-in-geriatric-inpatient-rehabilitation
#18
Saba Shahab, Diana-Felicia Nicolici, Alva Tang, Paul Katz, Linda Mah
OBJECTIVE: To evaluate the effect of depression on functional recovery in geriatric patients who have completed an inpatient rehabilitation program. DESIGN: Prospective cohort study. SETTING: Inpatient rehabilitation unit of a university-affiliated geriatric hospital. PARTICIPANTS: Convenience sample of patients (N=65; mean age, 81.6y; 25 men) admitted to rehabilitation over a 10-month period. Patients >60 years of age who were proficient in English and capable of providing informed consent were eligible to participate in the study...
March 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27442504/functional-connectivity-with-the-default-mode-network-is-altered-in-fibromyalgia-patients
#19
Nicholas Fallon, Yee Chiu, Turo Nurmikko, Andrej Stancak
Fibromyalgia syndrome (FMS) patients show altered connectivity with the network maintaining ongoing resting brain activity, known as the default mode network (DMN). The connectivity patterns of DMN with the rest of the brain in FMS patients are poorly understood. This study employed seed-based functional connectivity analysis to investigate resting-state functional connectivity with DMN structures in FMS. Sixteen female FMS patients and 15 age-matched, healthy control subjects underwent T2-weighted resting-state MRI scanning and functional connectivity analyses using DMN network seed regions...
2016: PloS One
https://www.readbyqxmd.com/read/27441902/quality-of-life-and-recommendations-for-further-care
#20
Michael S Putman, Hyo Jung Tak, Farr A Curlin, John D Yoon
OBJECTIVES: Physician recommendations for further medical treatment or palliative treatment only at the end of life may influence patient decisions. Little is known about the patient characteristics that affect physician-assessed quality of life or how such assessments are related to subsequent recommendations. DESIGN, SETTING, AND SUBJECTS: A 2010 mailed survey of practicing U.S. physicians (1,156/1,878 or 62% of eligible physicians responded). MEASUREMENTS AND MAIN RESULTS: Measures included an end of life vignette with five experimentally varied patient characteristics: setting, alimentation, pain, cognition, and communication...
November 2016: Critical Care Medicine
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