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https://www.readbyqxmd.com/read/29099025/not-a-straitjacket-affair-anthropometrically-derived-obesity-index-correlates-of-elevated-blood-pressure-among-university-undergraduates
#1
Chukwunonso E C C Ejike, Patricia O Ukegbu
Obesity is known to correlate with measures of blood pressure (BP). The nature of the correlations has, however, remained a subject of scientific enquiry, especially when BP phenotypes are disaggregated and obesity is determined by a variety of methods. This study examined the relationship between obesity and BP in young-adult Nigerians. A total of 1610 subjects (53.9% females) were recruited from five universities in the Igbo-speaking part of Nigeria. Relevant BP and anthropometric data were obtained following standard protocols...
May 12, 2017: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29024538/retinal-pulse-wave-velocity-measurement-using-spectral-domain-optical-coherence-tomography
#2
Qian Li, Lin Li, Shanhui Fan, Cuixia Dai, Xinyu Chai, Chuanqing Zhou
The human eyes provide a natural window for noninvasive measurement of the pulse wave velocity (PWV) of small arteries. By measuring the retinal PWV, the stiffness of small arteries can be assessed, which may better detect early vascular diseases. Therefore, retinal PWV measurement has attracted increasing attention. In this study, a jump-scanning method was proposed for non-invasive measurement of retinal PWV using spectral-domain OCT. The jump-scanning method uses the phase-resolved Doppler OCT to obtain the pulse shapes...
October 12, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28888490/type-2-diabetes-in-canadian-aboriginal-adolescents-risk-factors-and-prevalence
#3
Shelley Spurr, Jill Bally, Carol Bullin, Krista Trinder
PURPOSE: To identify the risk factors and prevalence rates of prediabetes and type 2 diabetes among northern Canadian Aboriginal adolescents. DESIGN AND METHODS: In this novel exploratory, quantitative study, 160 high school students (aged 13-21) from three northern, predominantly Canadian Aboriginal communities were screened for risk for prediabetes and type 2 diabetes including demographic data, family medical history, anthropometric measurements, blood pressure, and hemoglobin A1c (HbA1c)...
September 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28807551/the-optimal-cut-off-of-blood-pressure-related-to-left-ventricular-diastolic-dysfunction-and-remodeling-in-asian-diabetic-patients
#4
Ju Young Jung, Sung Keun Park, Jae-Hong Ryoo, Chang-Mo Oh, Jeong Gyu Kang, Kanghee Moon, Keum Ok Lee, Joong-Myung Choi
BACKGROUND: Although a recent randomized trial found no difference between intensive and standard blood pressure (BP) control in patients with diabetes mellitus (DM), the debate over the optimal BP target continues. Thus, the present study investigated the effect of BP on the subclinical left ventricular (LV) function and structural changes in diabetic patients. METHOD: A total of 2649 patients with DM who received echocardiography were enrolled in this study. Study population was stratified by three groups according to BP and presence of hypertension (normal, <130/80mmHg; prehypertension, ≥130/80mmHg without hypertension; hypertension, ≥140/90mmHg or history of hypertension)...
August 11, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28620620/ngal-as-an-early-predictive-marker-of-diabetic-nephropathy-in-children-and-young-adults-with-type-1-diabetes-mellitus
#5
Nektaria Papadopoulou-Marketou, Alexandra Margeli, Ioannis Papassotiriou, George P Chrousos, Christina Kanaka-Gantenbein, Jeanette Wahlberg
AIMS: Type 1 diabetes (T1D) is often associated with early microvascular complications. Previous studies demonstrated that increased systolic (SAP) and diastolic arterial blood pressures (DAP) are linked to microvascular morbidity in T1D. The aim of the study was to investigate the predictive role of neutrophil gelatinase-associated lipocalin (NGAL) in unravelling early cardio-renal dysfunction in T1D. METHODS: Two T1D patient groups participating in two-centre prospective cohorts were studied...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28590143/combined-exercise-training-reduces-blood-pressure-arterial-stiffness-and-insulin-resistance-in-obese-prehypertensive-adolescent-girls
#6
Won-Mok Son, Ki-Dong Sung, Leena P Bharath, Kong-Jib Choi, Song-Young Park
Childhood obesity is strongly linked to pathological processes for cardiovascular diseases in later adulthood. Obese adolescent girls with high blood pressure (BP) are reported to have increased arterial stiffness, which is associated with the development of hypertension and atherosclerosis. The present study sought to examine the impact of combined resistance and aerobic exercise (CRAE) training on BP, brachial-ankle pulse wave velocity (baPWV), insulin resistance (IR), and body composition in obese prehypertensive girls...
June 7, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28507172/hemodynamic-and-mechanical-properties-of-the-proximal-aorta-in-young-and-middle-aged-adults-with-isolated-systolic-hypertension-the-dallas-heart-study
#7
COMPARATIVE STUDY
Yuichiro Yano, Ian J Neeland, Colby Ayers, Ronald Peshock, Jarett D Berry, Donald M Lloyd-Jones, Philip Greenland, Gary F Mitchell, Wanpen Vongpatanasin
The aim of this study was to assess characteristic impedance (Zc) of the proximal aorta in young and middle-aged individuals with isolated systolic hypertension (ISH). Zc is an index of aortic stiffness relative to aortic size. In the Dallas Heart Study, 2001 untreated participants 18 to 64 years of age (mean age: 42.3 years; 44% black race) were divided into the following groups based on office blood pressure (BP) measurements: (1) optimal BP (systolic BP [SBP] <120 mm Hg and diastolic BP [DBP] <80 mm Hg; n=837); (2) prehypertension (SBP 120-139 mm Hg and DBP 80-89 mm Hg; n=821); (3) ISH (SBP ≥140 mm Hg and DBP <90 mm Hg; n=121); (4) isolated diastolic hypertension (SBP <140 mm Hg and DBP ≥90 mm Hg; n=44); and (5) systolic-diastolic hypertension (SBP ≥140 mm Hg and DBP ≥90 mm Hg; n=178)...
July 2017: Hypertension
https://www.readbyqxmd.com/read/28481823/favorable-outcomes-using-an-ehealth-approach-to-promote-physical-activity-and-nutrition-among-young-african-women
#8
Beth A Staffileno, Christy C Tangney, Louis Fogg
BACKGROUND: Internet and mobile devices are widely used and provide alternative approaches for promoting healthy lifestyles, yet less information is available describing outcomes of these approaches when used with young African American (AA) women at risk for developing hypertension. OBJECTIVE: In this study, we evaluated a Web-based, culturally relevant lifestyle change intervention targeting AA women (referred to as the eHealth study). METHODS: African American women, aged 18 to 45 years, with untreated prehypertension and Internet access were eligible for a 12-week study that incorporated social cognitive theory strategies...
May 5, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28423153/heterogeneity-in-blood-pressure-transitions-over-the-life-course-age-specific-emergence-of-racial-ethnic-and-sex-disparities-in-the-united-states
#9
Shakia T Hardy, Katelyn M Holliday, Sujatro Chakladar, Joseph C Engeda, Norrina B Allen, Gerardo Heiss, Donald M Lloyd-Jones, Pamela J Schreiner, Christina M Shay, Danyu Lin, Donglin Zeng, Christy L Avery
Importance: Many studies have assessed racial/ethnic and sex disparities in the prevalence of elevated blood pressure (BP) from childhood to adulthood, yet few have examined differences in age-specific transitions between categories of BP over the life course in contemporary, multiracial/multiethnic populations. Objective: To estimate age, racial/ethnic, and sex-specific annual net transition probabilities between categories of BP using Markov modeling of cross-sectional data from the National Health and Nutrition Examination Survey...
June 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28123182/the-influence-of-prehypertension-controlled-and-uncontrolled-hypertension-on-left-ventricular-diastolic-function-and-structure-in-the-general-korean-population
#10
Ju Young Jung, Sung Keun Park, Chang-Mo Oh, Jeong Gyu Kang, Joong-Myung Choi, Jae-Hong Ryoo, Jae-Hon Lee
Although hypertension is a clear risk factor for cardiovascular disease, how prehypertension and controlled hypertension influence left ventricular (LV) diastolic function and structure remain to be elucidated. Thus, this study was intended to investigate the link between LV diastolic dysfunction and structural changes in different categories of hypertension. A cohort of 52 111 Korean adults receiving echocardiograms was enrolled. The study population was stratified into five groups according to the following categories of hypertension and blood pressure (BP): normotensive (<120/80 mm Hg), prehypertensive (120-139/80-89 mm Hg), controlled hypertensive (<140/90 mm Hg), newly recognized hypertensive and uncontrolled hypertensive (⩾140/90 mm Hg)...
June 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28115515/does-extremely-low-birth-weight-predispose-to-low-renin-hypertension
#11
Anke Raaijmakers, Zhen-Yu Zhang, Jolien Claessens, Nicholas Cauwenberghs, Theun Pieter van Tienoven, Fang-Fei Wei, Lotte Jacobs, Elena Levtchenko, Steven Pauwels, Tatiana Kuznetsova, Karel Allegaert, Jan A Staessen
Low birth weight and prematurity are risk factors for hypertension in adulthood. Few studies in preterm or full-term born children reported on plasma renin activity (PRA). We tested the hypothesis that renin might modulate the incidence of hypertension associated with prematurity. We enrolled 93 prematurely born children with birth weight <1000 g and 87 healthy controls born at term, who were all examined at ≈11 years. Renal length and glomerular filtration rate derived from serum cystatin C were 0.28 cm (95% confidence interval, 0...
March 2017: Hypertension
https://www.readbyqxmd.com/read/28106664/ethnic-differences-regarding-arterial-stiffness-of-6-8-year-old-black-and-white-boys
#12
Gontse G Mokwatsi, Aletta E Schutte, Ruan Kruger
OBJECTIVES: Vascular deterioration is suggested to occur earlier in black than white populations, thereby increasing their risk for developing hypertension. To establish whether this is the case, we compared different estimates of arterial stiffness in black and white children and investigated the links with body composition and advanced glycation end products (AGEs) as potential contributors. METHODS: We included 40 black and 41 white boys (aged 6-8 years) from similar schools and measured arterial stiffness [pulse wave velocity (PWV) in different arterial sections, systemic arterial compliance and carotid stiffness estimates], anthropometry as well as urinary pentosidine as a marker of AGEs...
May 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27843840/blood-pressure-reduction-following-accumulated-physical-activity-in-prehypertensive
#13
Yogesh Saxena, Rani Gupta, Arsalan Moinuddin, Ravinder Narwal
CONTEXT: Accumulated moderate physical activity (PA) for 30 min in a day is the only recommended treatment of prehypertension. OBJECTIVE: We investigated autonomic modulation as a possible mechanism for the decrease in blood pressure (BP) during the rest periods in each 10 min session of PA. DESIGN SETTING AND PARTICIPANTS: We conducted a single-blind randomized multi-arm control trial on 40 prehypertensive (pre-HT) young male adults. METHODS: Participants were randomly divided by using random number table into four groups...
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27790426/prehypertension-and-its-determinants-in-apparently-healthy-young-adults
#14
Sunandha Senthil, Subbalakshmi Narasajjana Krishnadasa
INTRODUCTION: High incidence of prehypertension is reported in medical undergraduates. Prehypertension may progress to hypertension and eventually cardiovascular disease, a leading cause of morbidity and mortality. Therefore, identifying the risk factors of hypertension in prehypertensive state may aid in effective control of blood pressure. AIM: To find whether clustering of known risk factors of hypertension or certain individual risk factors alone affect blood pressure in young adults...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27779471/the-adaptive-role-of-nitric-oxide-and-hydrogen-sulphide-in-vasoactive-responses-of-thoracic-aorta-is-triggered-already-in-young-spontaneously-hypertensive-rats
#15
S Cacanyiova, A Berenyiova, F Kristek, M Drobna, K Ondrias, M Grman
The aorta plays an important role in blood pressure control so the early determination of its vasoactive properties could predict pathological changes in hypertension. The aim of study was to compare vasoactive properties and geometry of thoracic aorta (TA) and the participation of two vasoactive transmitters, nitric oxide (NO) and hydrogen sulphide (H2S), in TA tone regulation in young Wistar rats (WR) and spontaneously hypertensive rats (SHR). Four-weeks-old WR and SHR were used. Systolic blood pressure (sBP) was measured by plethysmography...
August 2016: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/27776426/tetrahydroxystilbene-glucoside-inhibits-excessive-autophagy-and-improves-microvascular-endothelial-dysfunction-in-prehypertensive-spontaneously-hypertensive-rats
#16
Qianqian Dong, Wenjuan Xing, Feng Fu, Zhenghua Liu, Jie Wang, Xiangyan Liang, Xuanxuan Zhou, Qian Yang, Wei Zhang, Feng Gao, Siwang Wang, Haifeng Zhang
Autophagy exists in vascular endothelial cells, but the relationship between autophagy and blood vessel dysfunction in hypertension remains elusive. This study aimed to investigate role of autophagy in vascular endothelial dysfunction in prehypertension and hypertension and the underlying mechanisms involved. Furthermore, we sought to determine if and how tetrahydroxystilbene glucoside (TSG), a resveratrol analogue and active ingredient of Polygonum multiflorum Thunb used for its cardiovascular protective properties in traditional Chinese medicine, influences vascular endothelial function...
2016: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/27754121/os-24-02-association-between-inflammation-obesity-and-prehypertension-in-16-25-year-old-australian-females
#17
Asvini Subasinghe, John Wark, Alexandra Gorelik, Suzanne Garland
OBJECTIVE: The relationship between inflammation and prehypertension has never been documented in adolescent females in Australia, where obesity is prevalent. We aimed to investigate the association between high sensitivity C-Reactive Protein (hs-CRP), obesity and prehypertension in young Australian females. DESIGN AND METHOD: Women aged 16-25 years, living in Victoria, were randomly recruited via targeted Facebook advertising for the Young Female Health Initiative and Safe-D studies...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27749691/influence-of-l-citrulline-and-watermelon-supplementation-on-vascular-function-and-exercise-performance
#18
Arturo Figueroa, Alexei Wong, Salvador J Jaime, Joaquin U Gonzales
PURPOSE OF REVIEW: L-Citrulline, either synthetic or in watermelon, may improve vascular function through increased L-arginine bioavailability and nitric oxide synthesis. This article analyses potential vascular benefits of L-citrulline and watermelon supplementation at rest and during exercise. RECENT FINDINGS: There is clear evidence that acute L-citrulline ingestion increases plasma L-arginine, the substrate for endothelial nitric oxide synthesis. However, the subsequent acute improvement in nitric oxide production and mediated vasodilation is inconsistent, which likely explains the inability of acute L-citrulline or watermelon to improve exercise tolerance...
January 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/27697448/endothelial-nitric-oxide-synthase-gene-polymorphisms-are-associated-with-cardiovascular-risks-in-prehypertensives
#19
Gopal Krushna Pal, Chandrasekaran Adithan, Gurusamy Umamaheswaran, Pravati Pal, Nivedita Nanda, Jagadeeswaran Indumathy, Avupati Naga Syamsunder
Though endothelial nitric oxide synthase (eNOS) gene polymorphism is documented in the causation of hypertension, its role in prehypertension has not been investigated. The present study was conducted in 172 subjects divided into prehypertensives (n = 57) and normotensives (n = 115). Cardiovascular (CV) parameters including baroreflex sensitivity (BRS) by continuous BP variability assessment and sympathovagal imbalance (SVI) by heart rate variability analysis were recorded. Biochemical parameters for insulin resistance (homeostatic model for assessment of insulin resistance), oxidative stress, lipid risk factors, renin, and inflammatory parameters were measured...
September 15, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27643048/os-24-02-association-between-inflammation-obesity-and-prehypertension-in-16-25-year-old-australian-females
#20
Asvini Subasinghe, John Wark, Alexandra Gorelik, Suzanne Garland
OBJECTIVE: The relationship between inflammation and prehypertension has never been documented in adolescent females in Australia, where obesity is prevalent. We aimed to investigate the association between high sensitivity C-Reactive Protein (hs-CRP), obesity and prehypertension in young Australian females. DESIGN AND METHOD: Women aged 16-25 years, living in Victoria, were randomly recruited via targeted Facebook advertising for the Young Female Health Initiative and Safe-D studies...
September 2016: Journal of Hypertension
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