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JOURNAL ARTICLE
Joseph Burns, Ezinne Emeruwa, Patrick Connell, Nirica Borges, Dana Reaves-O'Neal, Silvana Molossi
Anomalous aortic origin of the left coronary artery (AAOLCA) confers high risk for sudden cardiac arrest (SCA). This series aims to describe consecutive admissions with interarterial AAOLCA presenting with SCA and distinct clinical trajectories. An eight-year-old boy collapsed at school and received 10-min of cardiopulmonary resuscitation (CPR) and defibrillation prior to return of spontaneous circulation. He had no end-organ dysfunction and underwent uneventful coronary unroofing. In contrast, a 14-year-old boy presented with collapse while jogging...
April 17, 2024: World Journal for Pediatric & Congenital Heart Surgery
#2
JOURNAL ARTICLE
Avani Lamba, Thomas M Roston, Puck J Peltenburg, Dania Kallas, Sonia Franciosi, Krystien V V Lieve, Prince J Kannankeril, Minoru Horie, Seiko Ohno, Ramon Brugada, Takeshi Aiba, Peter Fischbach, Linda Knight, Jan Till, Sit-Yee Kwok, Vincent Probst, David Backhoff, Martin J LaPage, Anjan S Batra, Fabrizio Drago, Kristina Haugaa, Andrew D Krahn, Tomas Robyns, Heikki Swan, Terezia Tavacova, Joseph Atallah, Martin Borggrefe, Boris Rudic, Georgia Sarquella-Brugada, Ehud Chorin, Allison Hill, Janneke Kammeraad, Anna Kamp, Ian Law, James Perry, Jason D Roberts, Svjetlana Tisma-Dupanovic, Christopher Semsarian, Jonathan R Skinner, Jacob Tfelt-Hansen, Isabelle Denjoy, Antoine Leenhardt, Peter J Schwartz, Michael J Ackerman, Arthur A M Wilde, Christian van der Werf, Shubhayan Sanatani
BACKGROUND: Catecholaminergic polymorphic ventricular tachycardia (CPVT) may cause sudden cardiac death (SCD) despite medical therapy. Therefore, implantable cardioverter defibrillators (ICDs) are commonly advised. However, there are limited data on the outcomes of ICD use in children. OBJECTIVE: To compare the risk of arrhythmic events in pediatric CPVT patients with and without ICDs. METHODS: We compared the risk of SCD in RYR2 variant and phenotype positive symptomatic CPVT patients with and without ICDs, who were <19 years of age and had no history of sudden cardiac arrest (SCA) at phenotype diagnosis...
April 6, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#3
Fahad A Alfares, Jae Ho Sohn, Yoo Jin Lee, Rachel Farrell, Francesca N Delling, Kishor Avasarala, Anita J Moon-Grady, Shafkat Anwar, Karyn M Austin
Mitral annular disjunction (MAD) is a rare and under-recognized entity in the pediatric population. We present 2 cases of MAD in previously healthy pediatric patients and highlight clinical scenarios where MAD should be suspected.
May 1, 2024: JACC. Case reports
#4
REVIEW
Alessia Speranzon, Daniela Chicco, Paolo Bonazza, Raffaele D'Alfonso, Marco Bobbo, Biancamaria D'Agata Mottolese, Egidio Barbi, Thomas Caiffa
Brugada Syndrome is an "inherited" channelopathy characterized by a predisposition to syncope and sudden death. It typically presents in young adults but is also known to affect the pediatric population, even if the prevalence is low compared to the adult population. The diagnostic ECG pattern shows coved-type ST-segment elevation in the right precordial leads, occurring spontaneously or after provocative drug tests with IV administration of Class I antiarrhythmic drugs. However, the electrocardiographic findings may vary, and transient or concealed forms of the syndrome further complicate diagnosis, necessitating thorough evaluation and close clinical follow-up...
February 25, 2024: Children
#5
Nur Mashitah Abdullah, Adli Ali
BACKGROUND: Ryanodine receptor 2 ( RYR2 ) gene mutation causing catecholaminergic polymorphic ventricular tachycardia (CPVT) is one of the identified causes of sudden death in adults and children. CASE DESCRIPTION: We report a case of RYR2 gene mutation presented with cardiac arrest and recurrent syncopal attack with accidental finding of cardiac tumour. For the systematic review, we used four databases (Scopus, PubMed, Ovid and Google Scholar) to search articles with the terms " RYR2 gene mutation" and "catecholaminergic polymorphic ventricular tachycardia (CPVT)"...
February 29, 2024: Translational Pediatrics
#6
JOURNAL ARTICLE
Philipp Bohm, Sergio Barra, Orianne Weizman, Kumar Narayanan, Tim Meyer, Christian Schmied, Wulfran Bougouin, Xavier Jouven, Eloi Marijon
No abstract text is available yet for this article.
March 5, 2024: Circulation
#7
REVIEW
Audrey L Blewer, Blair L Bigham, Samantha Kaplan, Marina Del Rios, Marion Leary
BACKGROUND: Social determinants are associated with survival from out-of-hospital sudden cardiac arrest (SCA). Because prompt delivery of bystander CPR (B-CPR) doubles survival and B-CPR rates are low, we sought to assess whether gender, socioeconomic status (SES), race, and ethnicity are associated with lower rates of B-CPR and CPR training. METHODS: This scoping review was conducted as part of the continuous evidence evaluation process for the 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care as part of the Resuscitation Education Science section...
February 10, 2024: Healthcare (Basel, Switzerland)
#8
JOURNAL ARTICLE
Gabrielle Norrish, Marisa Gasparini, Ella Field, Elena Cervi, Juan Pablo Kaski
Up to 20% of children with sarcomeric hypertrophic cardiomyopathy (HCM) have disease-causing variants in genes coding for thin-filament proteins. However, data on genotype-phenotype correlations for thin-filament disease are limited. This study describes the natural history and outcomes of children with thin-filament-associated HCM and compares it to thick-filament-associated disease.Longitudinal data were collected from 40 children under 18 years with a disease-causing variant in a thin-filament protein from a single quaternary referral centre...
January 31, 2024: Journal of Medical Genetics
#9
REVIEW
Stefana Maria Moisa, Elena Lia Spoiala, Eliza Cinteza, Radu Vatasescu, Lacramioara Ionela Butnariu, Crischentian Brinza, Alexandru Burlacu
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited disease characterized by the progressive replacement of the normal myocardium by fibroadipocytic tissue. The importance of an early diagnosis is supported by a higher risk of sudden cardiac death in the pediatric population. We reviewed the literature on diagnosis, risk stratification, and prognosis in the pediatric population with ARVC. In case reports which analyzed children with ARVC, the most common sign was ventricular tachycardia, frequently presenting as dizziness, syncope, or even cardiac arrest...
January 12, 2024: Diagnostics
#10
Aphirak Mekmangkonthong, Khanittha Khusiwilai, Sudathip Paticheep, Duangtip Tiacharoen
Snake bite is a significant public health concern, particularly in tropical regions. Individuals who are bitten by neurotoxin snake commonly present with ptosis, ophthalmoparesis, muscle weakness, and diminished or absent of deep tendon reflexes. However, accurately determining the occurrence of a snakebite can sometimes be challenging, potentially leading to misdiagnosis. We present the case of a 2-year-old boy with sudden cardiac arrest. Following a brief resuscitation, he had return of spontaneous circulation...
2024: Case Reports in Pediatrics
#11
JOURNAL ARTICLE
Pezad Doctor, Bharti Sharma, Gerald Greil, Jeanne Dillenbeck, Mubeena Abdulkarim, Robert Jaquiss, Tarique Hussain, Munes Fares
Anomalous aortic origin of right coronary artery (AAORCA) is associated with myocardial ischemia and sudden cardiac arrest/death. Risk stratification remains challenging and relies upon provocative test results. This study describes the utility of dobutamine stress cardiovascular magnetic resonance (DSCMR) and potential benefit of strain analysis in children with AAORCA. All patients less than 21 years of age with AAORCA who underwent DSCMR between July 2018 and December 2022 were included. Visual wall motion abnormalities (VWMA) at rest and during protocolized increments of dobutamine infusion were assessed...
March 2024: Pediatric Cardiology
#12
JOURNAL ARTICLE
Francesca Graziano, Maurizio Schiavon, Alberto Cipriani, Francesco Savalla, Monica De Gaspari, Barbara Bauce, Stefania Rizzo, Chiara Calore, Gaetano Thiene, Stefano Paiaro, Cristina Basso, Alessandro Zorzi
OBJECTIVE: Evidence on the increased risk of sports-related sudden cardiac arrest and death (SCA/D) and the potential benefit of cardiovascular preparticipation screening (PPS) in children is limited. We assessed the burden and circumstances of SCA/D and the diagnostic yield of cardiovascular PPS in children aged 8-15 years. METHODS: Data on the incidence and causes of SCA/D from 2011 to 2020 were obtained from the Veneto region (Italy) sudden death registry, hospital records and local press...
March 8, 2024: British Journal of Sports Medicine
#13
JOURNAL ARTICLE
Tam T Doan, Carlos Bonilla-Ramirez, Lindsay Eilers, Dana Reaves-O'Neal, Shagun Sachdeva, Stephen J Dolgner, Prakash M Masand, Srinath Gowda, Athar M Qureshi, Ziyad Binsalamah, Silvana Molossi
OBJECTIVE: To describe clinical, functional, surgical, and outcomes data in pediatric patients with a myocardial bridge (MB) evaluated and managed following a standardized approach. METHODS: Prospective observational study included patients evaluated in the Coronary Artery Anomalies Program. Anatomy was determined by computed tomography angiography, myocardial perfusion by stress perfusion imaging, and coronary hemodynamic assessment by cardiac catheterization. RESULTS: A total of 39/42 patients with a complete evaluation for MB were included (12/2012-06/2022) at a median age of 14...
January 8, 2024: Journal of Thoracic and Cardiovascular Surgery
#14
Josiane Kerbage, Olamide O Dairo, Lauren Ketchum, Craig Smith, Joseph D Tobias
Commonly identified risk factors for perioperative cardiac arrest in pediatric-aged patients include cardiac surgery, younger age, comorbid conditions including pulmonary hypertension and cyanotic congenital heart disease, and emergency surgery. Although medication-related etiologies formerly predominated, the elimination of halothane from anesthetic care has resulted in a shift in etiology to hemodynamic events related to blood loss or hyperkalemia associated with the rapid administration of blood products...
December 2023: Cardiology Research
#15
REVIEW
Courtney Stanley Sundin, Laura Gomez, Brian Chapman
Amniotic fluid embolism (AFE) is a rare, sudden, and catastrophic complication of pregnancy that can result in cardiopulmonary arrest, potentially leading to death. The pathophysiology of an AFE includes an inflammatory and coagulopathic response due to fetal materials entering maternal circulation with the hallmark triad of symptoms: acute respiratory distress, cardiovascular collapse, and coagulopathy. Management of AFE should include high-quality cardiopulmonary resuscitation, immediate delivery of the fetus if applicable, early intubation to provide adequate oxygenation and ventilation, fluid volume resuscitation, and ongoing evaluation of coagulopathy...
January 2024: MCN. the American Journal of Maternal Child Nursing
#16
JOURNAL ARTICLE
Claudia Algaze, Henry Chubb, Anna M Deitch, Thomas Collins
Coronary artery stenosis (CAS) may affect up to 27% of patients with Williams syndrome (WS), which may lead to myocardial ischemia. Patients with WS face a 25- to 100-fold greater risk of sudden cardiac death, frequently linked to anesthesia. Assessing CAS requires either imaging while under general anesthesia or intraoperative assessment, with the latter considered the gold standard. Our study aimed to identify electrocardiogram (ECG) markers of myocardial ischemia in patients with WS or nonsyndromic elastin arteriopathy and documented CAS...
November 12, 2023: American Journal of Cardiology
#17
JOURNAL ARTICLE
Nouf S Almutairi, Nesrin A Alharthy, AlAnoud M Almaziad, AlJazi T Alsalloum, Rozanna A AlHarbi, Shamayel A Almulhem, Amal Yousif, Fatmah Othman
BACKGROUND: Pediatric out-of-hospital cardiac arrest is associated with high morbidity and mortality rates. Cardiopulmonary resuscitation (CPR), the practice of chest compressions combined with rescue breathing, is crucial for the success of out-of-hospital resuscitation after sudden cardiac arrest. Thus, imparting the requisite knowledge and skills to parents/caregivers can significantly enhance survival rates. This study investigated parental awareness of the impact of out-of-hospital pediatric CPR on survival rates in Saudi Arabia...
November 3, 2023: International Journal of Emergency Medicine
#18
JOURNAL ARTICLE
X Yang, Y Cheng, X Y Hong, Y X Guo, X Wang, Y Y Yang, J P Chu, Y P Jin, Y B Cheng, Y C Zhang, G P Lu
Objectives: To investigate the current application status and implementation difficulties of extracorporeal cardiopulmonary resuscitation (ECPR) in children with sudden cardiac arrest. Methods: This cross-sectional survey was conducted in 35 hospitals. A Children's ECPR Information Questionnaire on the implementation status of ECPR technology (abbreviated as the questionnaire) was designed, to collect the data of 385 children treated with ECPR in the 35 hospitals. The survey extracted the information about development of ECPR, the maintenance of extracorporeal membrane oxygenation (ECMO) machine, the indication of ECPR, and the difficulties of implementation in China...
November 2, 2023: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
#19
JOURNAL ARTICLE
Ashley M Bakker, Marijn Albrecht, Bas J Verkaik, Rogier C J de Jonge, Corinne M P Buysse, Nico A Blom, Lukas A J Rammeloo, Judith M A Verhagen, Maaike A Riedijk, Sing C Yap, Hanno L Tan, Janneke A E Kammeraad
UNLABELLED: Sudden cardiac arrest (SCA) studies are often population-based, limited to sudden cardiac death, and excluding infants. To guide prevention opportunities, it is essential to be informed of pediatric SCA etiologies. Unfortunately, etiologies frequently remain unresolved. The objectives of this study were to determine paediatric SCA etiology, and to evaluate the extent of post-SCA investigations and to assess the performance of previous cardiac evaluation in detecting conditions predisposing to SCA...
October 27, 2023: European Journal of Pediatrics
#20
JOURNAL ARTICLE
Suzanne Evans, Maureen Legg
School nurses play a major role in school readiness and emergency management, collaborating in safety assessment of schools and leading efforts to ensure the overall wellness of each child. Sudden cardiac arrest is a growing concern among students, and schools are a place of gathering, not only of our students and educators but also for the community, as family and friends support children in performances, sporting events, and religious or cultural activities. Implementing a school Cardiac Emergency Response Plan (CERP) provides a lifesaving resource for the entire community...
September 27, 2023: NASN School Nurse
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