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https://www.readbyqxmd.com/read/29778859/diagnosis-of-nonischemic-stage-b-heart-failure-in-type-2-diabetes-mellitus-optimal-parameters-for-prediction-of-heart-failure
#1
Ying Wang, Hong Yang, Quan Huynh, Mark Nolan, Kazuaki Negishi, Thomas H Marwick
OBJECTIVES: This study sought to identify whether impaired global longitudinal strain (GLS), diastolic dysfunction (DD), or left atrial enlargement (LAE) should be added to stage B heart failure (SBHF) criteria in asymptomatic patients with type 2 diabetes mellitus. BACKGROUND: SBHF is a precursor to clinical heart failure (HF), and its recognition justifies initiation of cardioprotective therapy. However, original definitions of SBHF were based on LV hypertrophy and impaired ejection fraction...
May 11, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29778590/sternoclavicular-joint-palpation-pain-the-shoulder-s-waddell-sign
#2
Brent A Ponce, Adam T Archie, Shawna L Watson, Parke W Hudson, Mariano E Menendez, Gerald McGwin, Eugene W Brabston
BACKGROUND: Pain is a complex and subjective reality and can be magnified by nonorganic or nonanatomic sources. Multiple studies have demonstrated a correlation between psychological factors and patients' perceptions of musculoskeletal pain and disability. In addition, nonorganic findings as part of the physical examination are well and long recognized. The purpose of this study was to analyze the relationship between a shoulder examination test, palpation of the sternoclavicular joint (SCJ), and psychosocial conditions including chronic pain, depression, and anxiety...
May 16, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29778410/paleo-oncology-taking-stock-and-moving-forward
#3
Casey L Kirkpatrick, Roselyn A Campbell, Kathryn J Hunt
This article serves as an introduction to the International Journal of Paleopathology's special issue, Paleo-oncology: Taking Stock and Moving Forward. Reflecting the goals of the special issue, this paper has been designed to provide an overview of the current state of paleo-oncology, to introduce new and innovative paleo-oncological research and ideas, and to serve as a catalyst for future discussions and progress. This paper begins with an overview of the paleo-oncological evidence that can be found in ancient remains, followed by a summary of significant paleo-oncological findings and methodological advances to date...
February 12, 2018: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29778382/comparison-of-the-prevalence-of-chronic-endometritis-as-determined-by-means-of-different-diagnostic-methods-in-women-with-and-without-reproductive-failure
#4
Yingyu Liu, Xiaoyan Chen, Jin Huang, Chi-Chiu Wang, Mei-Yung Yu, Susan Laird, Tin-Chiu Li
OBJECTIVE: To compare the prevalence of chronic endometritis (CE) when different diagnostic methods are used. DESIGN: Prospective observational study. SETTING: University-affiliated hospital. PATIENT(S): Four groups of women were studied, including women with proven fertility (Fertile; n = 40), unexplained recurrent miscarriage (RM; n = 93), recurrent implantation failure (RIF; n = 39), and infertile subjects undergoing endometrial scratch in a natural cycle preceding frozen-thawed embryo transfer (Infertility; n = 48)...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29778314/trends-in-high-grade-cervical-cancer-precursors-in-the-human-papillomavirus-vaccine-era
#5
Fredrick Oakley, Mohamed M Desouki, Manideepthi Pemmaraju, Julia M Gargano, Lauri E Markowitz, Martin Steinau, Elizabeth R Unger, Yuwei Zhu, Oluwole Fadare, Marie R Griffin
INTRODUCTION: The 2006 introduction of human papillomavirus vaccine targeted against genotypes 6, 11, 16, and 18 should result in decreased cervical dysplasia in vaccinated women. However, new cervical cancer guidelines to increase screening intervals complicate interpretation of trends. The hypothesis is that cervical dysplasia would decrease only in young vaccine-eligible women, and not older women. METHODS: The authors identified Davidson County, Tennessee, women aged 18-39 years with cervical intraepithelial neoplasia (CIN) grade 2 or greater and adenocarcinoma in situ, denoted as CIN2+, through pathology reports from laboratories serving this population...
May 16, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29777668/anterior-pericardiectomy-for-post-infective-constrictive-pericarditis-intermediate-term-outcomes
#6
Anil Acharya, Raamesh Koirala, Nivesh Rajbhandari, Jyotindra Sharma, Bijoy Rajbanshi
BACKGROUND: Post tubercular constrictive pericarditis is prevalent pericardial disease in developing countries. Pericardiectomy is the treatment of choice but considered a procedure of high morbidity and mortality. METHODS: From January 2003 to December 2013 we performed 130 pericardiectomies. Mean age was 22.95±12.55 years with 92 (71%) males. All patients were symptomatic; 118 (91%) were in NYHA class III / IV. Almost all patients were diagnosed to be of tubercular origin; 14 (11 %) histopathologically proven, 77 (59%) with definitive history while 39 (30%) suspected to be of tubercular origin and 91 (70%) received prior antitubercular treatment...
May 16, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29777581/in-vivo-performance-of-a-visible-wavelength-optical-sensor-for-monitoring-intestinal-perfusion-and-oxygenation
#7
Mitchell B Robinson, Anna M Wisniowiecki, Ryan J Butcher, Mark A Wilson, M Nance Ericson, Gerard L Cote
Traumatic injury resulting in hemorrhage is a prevalent cause of death worldwide. The current standard of care for trauma patients is to restore hemostasis by controlling bleeding and administering intravenous volume resuscitation. Adequate resuscitation to restore tissue blood flow and oxygenation is critical within the first hours following admission to assess severity and avoid complications. However, current clinical methods for guiding resuscitation are not sensitive or specific enough to adequately understand the patient condition...
May 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29777508/endothelial-progenitor-cells-in-heart-failure-an-authentic-expectation-for-potential-future-use-and-a-lack-of-universal-definition
#8
REVIEW
Andie H Djohan, Ching-Hui Sia, Poay Sian Lee, Kian-Keong Poh
Congestive heart failure (CHF) is a prevalent disease (especially among the elderly) with high mortality and morbidity rates. The pathological hallmark of CHF is a loss of cardiomyocytes leading to cardiac fibrosis and dysfunctional cardiac remodeling, which culminates in organ failure. Endothelial progenitor cells (EPCs) are bone marrow-derived cells that contribute to maintenance of the integrity of endothelial wall and protect ischemic myocardium through forming new blood vessels (vasculogenesis) or proliferation of pre-existing vasculature (angiogenesis)...
May 17, 2018: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/29777476/comparison-of-procalcitonin-a-potentially-new-inflammatory-biomarker-of-frailty-to-interleukin-6-and-c-reactive-protein-among-older-chinese-hospitalized-patients
#9
Ying Yang, Qiukui Hao, Joseph H Flaherty, Li Cao, Jianghua Zhou, Li Su, Yanjiao Shen, Birong Dong
AIM: Procalcitonin (PCT) has predictive value for patients with infectious diseases, but has not been studied in frailty. The purpose of this study was to compare PCT to two other inflammatory biomarkers [interleukin-6 (IL-6)] and C-reactive protein (CRP) in their association with frailty among older hospitalized patients. METHODS: Retrospective study of inpatients (June-December, 2016), who had all three biomarkers measured within 24 h of admission. Frailty was defined according to the Chinese version of a validated frailty scale...
May 17, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29777370/analysis-of-genetic-variability-of-respiratory-syncytial-virus-groups-a-and-b-in-kuwait
#10
Nada Madi, Wassim Chehadeh, Mohammed Asadzadeh, Mariam Al-Turab, Anfal Al-Adwani
Respiratory syncytial virus (RSV) is the most frequently identified viral agent in infants, children, and elderly people with acute respiratory tract infections (ARTIs). This study is the only one of its kind in Kuwait, and its purpose was to investigate the genetic variability of the G protein gene in RSV strains prevalent in Kuwait. Respiratory samples were collected from patients with ARTIs in various hospitals in Kuwait and subjected to reverse transcription PCR (RT-PCR) amplifying a fragment of the G gene of RSV...
May 19, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29777304/no-improvement-in-vitamin-d-status-in-german-infants-and-adolescents-between-2009-and-2014-despite-public-recommendations-to-increase-vitamin-d-intake-in-2012
#11
Clemens Kunz, Jürgen Hower, Anette Knoll, Kristin L Ritzenthaler, Thomas Lamberti
PURPOSE: Vitamin D is a key component for the growth and development of children and adolescents, influencing a multitude of functions. Worldwide epidemiological studies have shown that minimum vitamin D blood levels of ≥ 20.0 ng/ml, often defined as vitamin D sufficiency by international and national nutrition and pediatric organizations, are often not met in practice. In 2012 the D-A-CH (Germany, Austria, Switzerland) nutrition societies increased their vitamin D intake recommendations fourfold from 200 IU (5 µg) to 800 IU (20 µg) per day...
May 18, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29777299/-advanced-periocular-basal-cell-carcinoma-a-therapeutic-challenge
#12
B Lauterbach, V Kakkassery, D Debus, L M Heindl, E S Schultz
BACKGROUND: Basal cell carcinomas are the most common periocular malignant tumor. In advanced periocular basal cell carcinoma, vismodegib is a new treatment option which might potentially avoid surgical eye removal. CASE REPORT: We treated a 76-year-old patient unwilling to consent to surgery with vismodegib for advanced periocular basal cell carcinoma on the left forehead that had already undergone several previous treatments. After initial partial remission, the tumor regrew under ongoing therapy, so that radical surgical excision including orbital exenteration was performed...
May 17, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29777284/current-drug-therapy-for-heart-failure-with-reduced-ejection-fraction
#13
D Berliner, M Hallbaum, J Bauersachs
The prevalence of heart failure has been steadily increasing during the past few years, with a further increase predicted in the years to come. Without treatment, the syndrome of heart failure has a very poor prognosis. Advances in drug treatments and the consequent implementation of a guideline-recommended drug therapy have significantly improved the prognosis in heart failure with reduced ejection fraction (HFrEF). Besides angiotensin-converting enzyme (ACE) inhibitors (ACEi) or angiotensin receptor blockers, beta-blockers and diuretics treatment with mineralocorticoid receptor antagonists and ivabradine have become standard in the therapy of symptomatic patients with HFrEF...
May 18, 2018: Herz
https://www.readbyqxmd.com/read/29777162/hiv-and-vertebral-fractures-a-systematic-review-and-metanalysis
#14
Thales A S H Ilha, Fabio V Comim, Rafaela M Copes, Juliet E Compston, Melissa O Premaor
The survival of HIV-infected patients has increased with the advent of antiretroviral therapy with the emergence of new comorbidities. Vertebral fracture is a manifestation of reduced bone strength and osteoporosis. This study aims to assess the frequency of spine fractures in HIV-positive men and women aged over 18 years. We performed a systematic review of randomized controlled trials, cohort studies, cross-sectional studies, and case-control studies. Studies that evaluated morphometric and/or clinical vertebral fracture were included...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776620/physical-neighborhood-and-social-environment-beliefs-about-sleep-sleep-hygiene-behaviors-and-sleep-quality-among-african-americans
#15
Soohyun Nam, Robin Whittemore, Sunyoung Jung, Carl Latkin, Trace Kershaw, Nancy S Redeker
OBJECTIVES: African Americans (AAs) have a higher prevalence of sleep disorders than other racial/ethnic groups. However, little is known about the relationships among individual and neighborhood factors related to sleep quality in AAs. The purposes of this study were to (1) describe beliefs about sleep, sleep hygiene behaviors, and sleep quality among AAs; and (2) examine the relationships among sociodemographic characteristics, neighborhood environment, beliefs about sleep, sleep hygiene behaviors, and sleep quality...
June 2018: Sleep Health
https://www.readbyqxmd.com/read/29776360/the-impact-of-telephone-follow-up-on-adverse-events-for-aboriginal-people-with-chronic-disease-in-new-south-wales-australia-a-retrospective-cohort-study
#16
Amanda Jayakody, Erin Passmore, Christopher Oldmeadow, Jamie Bryant, Mariko Carey, Eunice Simons, Aaron Cashmore, Louise Maher, Kiel Hennessey, Jacinta Bunfield, Maurice Terare, Andrew Milat, Rob Sanson-Fisher
BACKGROUND: Chronic diseases are more prevalent and occur at a much younger age in Aboriginal people in Australia compared with non-Aboriginal people. Aboriginal people also have higher rates of unplanned hospital readmissions and emergency department presentations. There is a paucity of research on the effectiveness of follow up programs after discharge from hospital in Aboriginal populations. This study aimed to assess the impact of a telephone follow up program, 48 Hour Follow Up, on rates of unplanned hospital readmissions, unplanned emergency department presentations and mortality within 28 days of discharge among Aboriginal people with chronic disease...
May 18, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29776012/evolving-self-view-and-body-image-concerns-in-female-post-operative-bariatric-surgery-patients
#17
Tamara O Perdue, Ann Schreier, Melvin Swanson, Janice Neil, Robert Carels
AIMS AND OBJECTIVES: This research study explores the experience of post-operative bariatric surgery patients as they adjust to diminished weight and differentiates that adjustment from the more general concept of body image. BACKGROUND: Bariatric surgery is an effective way to reduce weight and co-morbidities associated with obesity. Complete success requires that patients must adjust psychologically as they lose weight. If this does not occur, bariatric patients may experience a 'mind-body lag' in which the patient's internal body image lags behind the external changes...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775832/stressed-out-an-investigation-of-whether-allostatic-load-mediates-associations-between-neighbourhood-deprivation-and-health
#18
Lucy Prior, David Manley, Kelvyn Jones
Deprived neighbourhoods have long been associated with poorer health outcomes. However, many quantitative studies have not evidenced the mechanisms through which place 'gets under the skin' to influence health. The increasing prevalence of biosocial data provides new opportunities to explore these mechanisms and incorporate them into models of contextual effects. The stress pathway is a key biosocial mechanism; however, few studies have explicitly tested it in neighbourhood associations. This paper addresses this gap by investigating whether allostatic load, a biological response to chronic stress, mediates relationships of neighbourhood deprivation to physical and mental health...
May 15, 2018: Health & Place
https://www.readbyqxmd.com/read/29775599/model-to-determine-risk-of-pancreatic-cancer-in-patients-with-new-onset-diabetes
#19
Ayush Sharma, Harika Kandlakunta, Sajan Jiv Singh Nagpal, Feng Ziding, William Hoos, Gloria M Petersen, Suresh T Chari
BACKGROUND & AIMS: Of subjects with new-onset diabetes (based on glycemia) over the age of 50 years, approximately 1% are diagnosed with pancreatic cancer within 3 years. We aimed to develop and validate a model to determine risk of pancreatic cancer in individuals with new-onset diabetes. METHODS: We retrospectively collected data from 4 independent, non-overlapping cohorts of patients (n=1561) with new-onset diabetes (based on glycemia; data collected at date of diagnosis and 12 months before) in the Rochester Epidemiology Project, from January 1, 2000 through December 31, 2015 to create our model...
May 15, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29775296/incorporation-of-a-theranostic-two-tone-luminescent-silver-complex-into-biocompatible-agar-hydrogel-composite-for-the-eradication-of-eskape-pathogens-in-a-skin-and-soft-tissue-infection-model
#20
Miguel N Pinto, Jorge Martinez-Gonzalez, Indranil Chakraborty, Pradip K Mascharak
Microbial invasion and colonization of the skin and underlying soft tissues are among the most common types of infections, becoming increasingly prevalent in hospital settings. Systemic antibiotic chemotherapies are now extremely limited due to emergence of drug-resistant Gram-positive and multidrug-resistant Gram-negative bacterial strains. Topical administration of antimicrobials provides an effective route for the treatment of skin and soft tissue infections (SSTIs). Therefore, the development of new and effective materials for the delivery of these agents is of paramount importance...
May 18, 2018: Inorganic Chemistry
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