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Pediatric electrophysiology

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https://www.readbyqxmd.com/read/29415597/prediction-of-postnatal-arrhythmia-in-fetuses-with-cardiac-rhabdomyoma
#1
Tetsuya Ide, Takekazu Miyoshi, Shinji Katsuragi, Reiko Neki, Ken-Ichi Kurosaki, Isao Shiraishi, Jun Yoshimatsu, Tomoaki Ikeda
OBJECTIVES: Fetal cardiac rhabdomyomas are rare but well known to be associated with arrhythmia or conduction abnormalities. However, since in utero electrophysiological information is quite limited, it remains unclear which type of rhabdomyoma will develop arrhythmia after birth. The aim of this study is to identify factors that predict postnatal arrhythmia requiring therapy in fetuses with cardiac rhabdomyoma. STUDY DESIGN: A retrospective review of infants prenatally diagnosed with cardiac rhabdomyoma was performed at our tertiary pediatric cardiac center between 1990 and 2016...
February 7, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29397525/coronary-sinus-morphology-in-pediatric-patients-with-supraventricular-tachycardia
#2
Matthew B Ambrose, Jennifer N Avari Silva, Michael Rudokas, Tammy M Bowman, Joshua Murphy, George F Van Hare
PURPOSE: The anatomic basis of atrioventricular node reentrant tachycardia (AVNRT) remains incompletely characterized in children. Differences in coronary sinus (CS) size and morphology have been observed in adults with AVNRT but have not been well characterized in children. METHODS: Children (< 18 years) brought to the EP lab with supraventricular tachycardia for ablation underwent CS venography. A blinded pediatric interventional cardiologist performed CS measurements, which were indexed to body surface area...
February 3, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29376095/massive-cortical-reorganization-is-reversible-following-bilateral-transplants-of-the-hands-evidence-from-the-first-successful-bilateral-pediatric-hand-transplant-patient
#3
William Gaetz, Sudha K Kessler, Tim P L Roberts, Jeffrey I Berman, Todd J Levy, Michelle Hsia, Deborah Humpl, Erin S Schwartz, Sandra Amaral, Ben Chang, Lawrence Scott Levin
In this repeated measures case study, we show that sensory deafferentation after limb amputation leads to changes in cortical somatotopic maps which are reversible after restoration of sensory input. Using magnetoencephalography (MEG), we observed in a child with bilateral hand transplants large-scale shifts in somatosensory lip cortical representation from anatomic hand area to anatomic face region. After recovery of tactile sensation in the digits, responses to finger stimulation were localized to orthotopic sensory cortex, but with atypical electrophysiologic features (amplitude and frequencies)...
January 2018: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/29366866/international-consensus-icon-on-audiological-assessment-of-hearing-loss-in-children
#4
A Farinetti, A Raji, H Wu, B Wanna, C Vincent
The prevalence of hearing loss in newborns and infants is estimated between 1 to 3.47 cases per 1000 live births. Early diagnosis and rehabilitation of congenital hearing loss are mandatory in order to achieve a satisfactory linguistic and cognitive development. Without appropriate opportunities to learn language, these children will fall behind their normal hearing peers in communication, cognition, reading and socio-emotional development. After promising results, neonatal screening for hearing loss and audiological evaluation are becoming more extensively carried out...
January 20, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29333742/parvalbumin-fast-spiking-interneurons-are-selectively-altered-by-pediatric-traumatic-brain-injury
#5
Joshua Nichols, George Reed Bjorklund, Jason Newbern, Trent Anderson
Pediatric traumatic brain injury (TBI) is a leading cause of death and disability in children. Traditionally, ongoing neurodevelopment and neuroplasticity have thought to confer children with an advantage following TBI. However, recent findings indicate that the pediatric brain may be more sensitive to brain injury. Inhibitory interneurons are essential for proper cortical function and implicated in the pathophysiology of TBI, yet few studies have directly examined for TBI induced changes to interneurons themselves...
January 15, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29302263/radiofrequency-catheter-ablation-of-atrioventricular-nodal-reentry-tachycardia-in-children-and-adolescents-a-single-center-experience
#6
Myung Chul Hyun
Purpose: Atrioventricular nodal reentry tachycardia (AVNRT) is less common in pediatric patients than in adult patients. Thus, data for pediatric AVNRT patients are insufficient. Hence, we aimed to analyze the patient characteristics, treatment, and any recurrences in pediatric AVNRT patients. Methods: We reviewed the records of 50 pediatric AVNRT patients who had undergone radiofrequency catheter ablation (RFCA) between January 1998 and December 2016 at a single regional center...
December 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29288902/diagnostic-evaluation-and-surgical-management-of-pediatric-insular-epilepsy-utilizing-magnetoencephalography-and-invasive-eeg-monitoring
#7
Raheel Ahmed, Hiroshi Otsubo, Carter Snead, Elizabeth Donner, Elysa Widjaja, Ayako Ochi, James M Drake, James T Rutka
INTRODUCTION: The diagnosis and surgical management of pediatric patients with insular epilepsy is challenging due to variable and indistinct seizure semiology arising within the insular cortex. In addition, surgical approaches are associated with potential morbidity given the regional neurosurgical and vascular anatomy. Our institutional experience in evaluation and surgical management of insular epilepsy patients is presented. Diagnostic evaluation, surgical treatment and seizures outcomes are highlighted...
December 20, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29286280/the-2017-seventh-world-congress-of-pediatric-cardiology-cardiac-surgery-week-in-review-electrophysiology
#8
Mitchell I Cohen, Susan Etheridge, Shubhayan Sanatani, Alpay Celiker
No abstract text is available yet for this article.
December 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29250266/intravenous-sotalol-reintroducing-a-forgotten-agent-to-the-electrophysiology-therapeutic-arsenal
#9
REVIEW
Syeda Atiqa Batul, Rakesh Gopinathannair
Sotalol is a racemic mixture possessing beta-blocker and class III anti arrhythmic properties. Approved by US food and drug administration (FDA) since 2009 based on its bioequivalence with oral sotalol, clinicians are less familiar with the potential uses of the intravenous form despite its re-launch in United States in 2015. Available literature suggests that intravenous sotalol in recommended doses can be safely administered in adult and pediatric population achieving rapid reliable therapeutic plasma concentration and without additional proarrhythmic effects when compared to its oral form as well as other antiarrhythmic medications...
February 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29224642/drug-induced-cardiac-abnormalities-in-premature-infants-and-neonates
#10
REVIEW
Luana Pesco-Koplowitz, Gary Gintant, Robert Ward, Dominique Heon, Muriel Saulnier, Jeff Heilbraun
The Cardiac Safety Research Consortium (CSRC) is a transparent, public-private partnership that was established in 2005 as a Critical Path Program and formalized in 2006 under a Memorandum of Understanding between the United States Food and Drug Administration and Duke University. Our continuing goal is to advance paradigms for more efficient regulatory science related to the cardiovascular safety of new therapeutics, both in the United States and globally, particularly where such safety questions add burden to innovative research and development...
January 2018: American Heart Journal
https://www.readbyqxmd.com/read/29218095/effect-of-repeated-neonatal-sevoflurane-exposure-on-the-learning-memory-and-synaptic-plasticity-at-juvenile-and-adult-age
#11
Xiaoli Liang, Yi Zhang, Chao Zhang, Chunchun Tang, Yi Wang, Juanjuan Ren, Xi Chen, Yu Zhang, Zhaoqiong Zhu
Currently sevoflurane is the volatile anesthetic most wildly used in pediatric surgery. Whether neonatal exposure to sevoflurane brings about a long-lasting adverse impact even at juvenile and adult age, attracts extensive concerns. However, to date the consensus has not been reached and how exposure to sevoflurane in early life affects long-term ability of learning and memory is not fully elucidated. To obtain further insight into this issue, 32 neonatal SD rats were assigned into control group (group C, n=16) and sevoflurane group (group SEV, n=16)...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/29197727/development-of-face-recognition-dynamic-causal-modelling-of-meg-data
#12
Wei He, Blake W Johnson
Electrophysiological studies of adults indicate that brain activity is enhanced during viewing of repeated faces, at a latency of about 250ms after the onset of the face (M250/N250). The present study aimed to determine if this effect was also present in preschool-aged children, whose brain activity was measured in a custom-sized pediatric MEG system. The results showed that, unlike adults, face repetition did not show any significant modulation of M250 amplitude in children; however children's M250 latencies were significantly faster for repeated than non-repeated faces...
November 23, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29147786/risk-factors-for-development-of-ectopic-atrial-tachycardia-in-post-operative-congenital-heart-disease
#13
Bradley C Clark, John T Berger, Charles I Berul, Richard A Jonas, Jonathan R Kaltman, Julianne Lapsa, Dilip S Nath, Elizabeth D Sherwin, Pranava Sinha, David Zurakowski, Jeffrey P Moak
Ectopic atrial tachycardia (EAT) is common in surgically repaired congenital heart disease (CHD) and carries the potential for significant hemodynamic compromise. Our objective was to determine the incidence, and risk factors of EAT after CHD surgery. Prospective study of patients that underwent surgery for CHD from February to October 2016 was performed. Demographic, perioperative and electrophysiologic data were collected. Sustained EAT (> 30 s) was documented by telemetry or electrocardiogram and confirmed by a pediatric electrophysiologist...
November 17, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29115488/repeated-inhalation-of-sevoflurane-inhibits-the-information-transmission-of-purkinje-cells-and-delays-motor-development-via-the-gabaa-receptor-%C3%AE%C2%B5-subunit-in-neonatal-mice
#14
Hong Fang, Ze-Hua Wang, Ying-Jiang Bu, Zhi-Jun Yuan, Guo-Qiang Wang, Yan Guo, Xiao-Yun Cheng, Wen-Jie Qiu
General anesthesia is widely used in pediatric surgery, although the influence of general anesthesia on cerebellar information transmission and motor function is unclear. In the present study, neonatal mice received repeated inhalation of sevoflurane, and electrophysiological alterations in Purkinje cells (PCs) and the development of motor functions were detected. In addition, γ‑aminobutyric acidA receptor ε (GABAA‑R ε) subunit knockout mice were used to investigate the mechanism of action of sevoflurane on cerebellar function...
November 3, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29060725/elucidating-age-specific-patterns-from-background-electroencephalogram-pediatric-datasets-via-parafac
#15
E Kinney-Lang, L Spyrou, A Ebied, R Chin, J Escudero
Brain-computer interfaces (BCI) have the potential to provide non-muscular rehabilitation options for children. However, progressive changes in electrophysiology throughout development may pose a potential barrier in the translation of BCI rehabilitation schemes to children. Tensors and multiway analysis could provide tools which help characterize subtle developmental changes in electroencephalogram (EEG) profiles of children, thus supporting translation of BCI paradigms. Spatial, spectral and subject information of age-matched pediatric subjects in two EEG datasets were used to form 3-dimensional tensors for use in parallel factor analysis (PARAFAC) and direct projection comparison...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29023243/pediatric-auditory-brainstem-implantation-surgical-electrophysiologic-and-behavioral-outcomes
#16
Holly F B Teagle, Lillian Henderson, Shuman He, Matthew G Ewend, Craig A Buchman
OBJECTIVES: The objectives of this study were to demonstrate the safety of auditory brainstem implant (ABI) surgery and document the subsequent development of auditory and spoken language skills in children without neurofibromatosis type II (NFII). DESIGN: A prospective, single-subject observational study of ABI in children without NFII was undertaken at the University of North Carolina at Chapel Hill. Five children were enrolled under an investigational device exemption sponsored by the investigators...
October 11, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28984782/chiari-type-i-malformation-with-occult-tethered-cord-syndrome-in-a-child-a-case-report
#17
Yuan Zhou, Lin Zhu, Yixing Lin, Huilin Cheng
RATIONALE: Chiari type I malformation (CM1) and occult tethered cord syndrome (OTCS) are considered to be malformations associated with subtle structural abnormalities of the terminal filum. Few studies have reported patients with CM1 and OTCS. Treatment strategy for patients of CM1 associated with OTCS is controversial. PATIENT CONCERNS: A 14-year-old child was admitted with intermittent pain and numbness in the right upper limb. And he had urinary frequency, neck pain, back pain, and numbness simultaneously...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28974521/update-to-practice-standards-for-electrocardiographic-monitoring-in-hospital-settings-a-scientific-statement-from-the-american-heart-association
#18
REVIEW
Kristin E Sandau, Marjorie Funk, Andrew Auerbach, Gregory W Barsness, Kay Blum, Maria Cvach, Rachel Lampert, Jeanine L May, George M McDaniel, Marco V Perez, Sue Sendelbach, Claire E Sommargren, Paul J Wang
BACKGROUND AND PURPOSE: This scientific statement provides an interprofessional, comprehensive review of evidence and recommendations for indications, duration, and implementation of continuous electro cardiographic monitoring of hospitalized patients. Since the original practice standards were published in 2004, new issues have emerged that need to be addressed: overuse of arrhythmia monitoring among a variety of patient populations, appropriate use of ischemia and QT-interval monitoring among select populations, alarm management, and documentation in electronic health records...
November 7, 2017: Circulation
https://www.readbyqxmd.com/read/28939092/spanish-catheter-ablation-registry-16th-official-report-of-the-spanish-society-of-cardiology-working-group-on-electrophysiology-and-arrhythmias-2016
#19
Adolfo Fontenla, Javier García-Fernández, José Luis Ibáñez
INTRODUCTION AND OBJECTIVES: This report describes the findings of the 2016 Spanish Catheter Ablation Registry. METHODS: Data were retrospectively collected by means of a standardized questionnaire completed by each of the participating centers. RESULTS: Data were collected from 83 centers. A total of 13 482 ablation procedures were performed (the highest historically reported in this registry), with a mean of 162.4 ± 116 and a median of 136 procedures per center...
November 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28918222/vision-assessments-and-interventions-for-infants-0-2-years-at-high-risk-for-cerebral-palsy-a-systematic-review
#20
REVIEW
Olena D Chorna, Andrea Guzzetta, Nathalie L Maitre
We performed a systematic review and evaluated the level of evidence of vision interventions and assessments for infants at high risk for or with a diagnosis of cerebral palsy from zero to two years of age. Articles were evaluated based on the level of methodologic quality, evidence, and clinical utilization. Thirty publications with vision assessments and five with vision interventions met criteria for inclusion. Assessments included standard care neuroimaging, electrophysiology, and neuro-ophthalmologic examination techniques that are utilized clinically with any preverbal or nonverbal pediatric patient...
November 2017: Pediatric Neurology
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