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Pediatric electrophysiology

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https://www.readbyqxmd.com/read/28687669/atrioventricular-nodal-reentrant-tachycardia-in-patients-with-congenital-heart-disease-outcome-after-catheter-ablation
#1
John Papagiannis, Daniel Joseph Beissel, Ulrich Krause, Michel Cabrera, Marta Telishevska, Stephen Seslar, Christopher Johnsrude, Charles Anderson, Svjetlana Tisma-Dupanovic, Diana Connelly, Dimosthenis Avramidis, Christopher Carter, Laszlo Kornyei, Ian Law, Nicholas Von Bergen, Jan Janusek, Jennifer Silva, Eric Rosenthal, Mark Willcox, Peter Kubus, Gabriele Hessling, Thomas Paul
BACKGROUND: The relationship of atrioventricular nodal reentrant tachycardia to congenital heart disease (CHD) and the outcome of catheter ablation in this population have not been studied adequately. METHODS AND RESULTS: A multicenter retrospective study was performed on patients with CHD who had atrioventricular nodal reentrant tachycardia and were treated with catheter ablation. There were 109 patients (61 women), aged 22.1±13.4 years. The majority, 86 of 109 (79%), had CHD resulting in right heart pressure or volume overload...
July 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28680486/longitudinal-comparison-of-auditory-steady-state-evoked-potentials-in-preterm-and-term-infants-the-maturation-process
#2
Ana Constantino Sousa, Dayane Domeneghini Didoné, Pricila Sleifer
Introduction  Preterm neonates are at risk of changes in their auditory system development, which explains the need for auditory monitoring of this population. The Auditory Steady-State Response (ASSR) is an objective method that allows obtaining the electrophysiological thresholds with greater applicability in neonatal and pediatric population. Objective  The purpose of this study is to compare the ASSR thresholds in preterm and term infants evaluated during two stages. Method  The study included 63 normal hearing neonates: 33 preterm and 30 term...
July 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28677509/therapy-of-cardiac-arrhythmias-in-children-an-emerging-role-of-electroanatomical-mapping-systems
#3
Casale Matteo, Mezzetti Maurizio, Tulino Viviana, Michele Scarano, Busacca Paolo, Dattilo Giuseppe
INTRODUCTION: Cardiac arrhythmias are challenging diseases in childhood. Most of them in pediatric subjects (90.2%) are atrioventricular reentrant tachycardias and atrioventricular nodal reentrant tachycardias. The standard 12-lead ECG is a highly accurate diagnostic tool but an invasive electrophysiological study is often required. The main concern about this kind of procedures is their invasive nature and the need of radiations, so antiarrhythmic agents are currently the first line therapy...
July 5, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28620754/variation-in-pediatric-post-ablation-care-a%C3%A2-survey-of-the-pediatric-and%C3%A2-congenital-electrophysiology-society-paces
#4
Brynn E Dechert, Macdonald Dick, David J Bradley, Martin J LaPage
Although catheter ablation is a standard treatment for pediatric arrhythmias, there are no consensus guidelines for follow-up care. This study describes the variation in post-ablation practices identified through a survey of the pediatric and congenital electrophysiology society (PACES). Pediatric and congenital electrophysiology society members were invited to participate in an online survey of post-ablation practices in September 2014. Survey questions targeted routine post-ablation practices for three common arrhythmia substrates: atrioventricular nodal reentry tachycardia, concealed accessory pathways (AP), and manifest APs...
June 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28604577/pain-after-cochlear-implantation-an-unusual-complication
#5
Charlotte Celerier, Isabelle Rouillon, Marion Blanchard, Marine Parodi, Françoise Denoyelle, Natalie Loundon
OBJECTIVE: To analyze clinical signs and better define the underestimated long-term pain after implantation, to discuss etiological hypothesis, and to propose our department treatment algorithm and results. STUDY DESIGN AND SETTING: Retrospective review of children implanted with complaints of atypical pain in the area of device implantation, not in the immediate postoperative period, more than or equal to 4 on the Visual Analog Pain Scale (VAPS: 0-10) in the ENT pediatric department of Trousseau and Necker Enfants Malades Hospitals between 1998 and 2015...
August 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28589518/forty-years-of-sodium-channels-structure-function-pharmacology-and-epilepsy
#6
William A Catterall
Voltage-gated sodium channels initiate action potentials in brain neurons. In the 1970s, much was known about the function of sodium channels from measurements of ionic currents using the voltage clamp method, but there was no information about the sodium channel molecules themselves. As a postdoctoral fellow and staff scientist at the National Institutes of Health, I developed neurotoxins as molecular probes of sodium channels in cultured neuroblastoma cells. During those years, Bruce Ransom and I crossed paths as members of the laboratories of Marshall Nirenberg and Philip Nelson and shared insights about sodium channels in neuroblastoma cells from my work and electrical excitability and synaptic transmission in cultured spinal cord neurons from Bruce's pioneering electrophysiological studies...
June 7, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28571426/versatile-synchronized-real-time-meg-hardware-controller-for-large-scale-fast-data-acquisition
#7
Limin Sun, Menglai Han, Kevin Pratt, Douglas Paulson, Christoph Dinh, Lorenz Esch, Yoshio Okada, Matti Hämäläinen
Versatile controllers for accurate, fast, and real-time synchronized acquisition of large-scale data are useful in many areas of science, engineering, and technology. Here, we describe the development of a controller software based on a technique called queued state machine for controlling the data acquisition (DAQ) hardware, continuously acquiring a large amount of data synchronized across a large number of channels (>400) at a fast rate (up to 20 kHz/channel) in real time, and interfacing with applications for real-time data analysis and display of electrophysiological data...
May 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28538829/maturation-of-long-latency-auditory-evoked-potentials-in-hearing-children-systematic-review
#8
REVIEW
Liliane Aparecida Fagundes Silva, Fernanda Cristina Leite Magliaro, Ana Claudia Martinho de Carvalho, Carla Gentile Matas
Purpose: To analyze how Auditory Long Latency Evoked Potentials (LLAEP) change according to age in children population through a systematic literature review. Research strategies: After formulation of the research question, a bibliographic survey was done in five data bases with the following descriptors: Electrophysiology (Eletrofisiologia), Auditory Evoked Potentials (Potenciais Evocados Auditivos), Child (Criança), Neuronal Plasticity (Plasticidade Neuronal) and Audiology (Audiologia)...
May 15, 2017: CoDAS
https://www.readbyqxmd.com/read/28515113/force-sensing-catheters-during-pediatric-radiofrequency-ablation-the-federation-study
#9
Aarti S Dalal, Hoang H Nguyen, Tammy Bowman, George F Van Hare, Jennifer N Avari Silva
BACKGROUND: Based on data from studies of atrial fibrillation ablations, optimal parameters for the TactiCath (TC; St. Jude Medical, Inc) force-sensing ablation catheter are a contact force of 20 g and a force-time integral of 400 g·s for the creation of transmural lesions. We aimed to evaluate TC in pediatric and congenital heart disease patients undergoing ablation. METHODS AND RESULTS: Comprehensive chart and case reviews were performed from June 2015 to March 2016...
May 17, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28456889/childhood-hereditary-ataxias-experience-from-a-tertiary-referral-university-hospital-in-turkey
#10
Elif Acar Arslan, Rahşan Göçmen, Kader Karlı Oğuz, Gökçen Düzgün Konuşkan, Esra Serdaroğlu, Haluk Topaloğlu, Meral Topçu
Hereditary ataxias are a group of genetic disorders that are progressive and heterogeneous. The purpose of this study was to develop a practical and time-efficient approach to diagnosing childhood hereditary ataxias by analyzing characteristics and final diagnosis at a tertiary referral clinic for pediatric neurology. 196 patients admitted to the pediatric neurology department were included. The medical records were examined for demographic features, neurological, laboratory, electrophysiological, cranial imaging, and pathological findings, and for genetic studies...
April 29, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28453898/electrophysiological-effects-of-anthracyclines-in-adult-survivors-of-pediatric-malignancy
#11
Timothy M Markman, Kathryn Ruble, David Loeb, Allen Chen, Yiyi Zhang, Gary S Beasley, W Reid Thompson, Saman Nazarian
BACKGROUND: Anthracycline use is limited by cardiotoxicity, including arrhythmias and left ventricular (LV) dysfunction. We aim to characterize the association between electrophysiological changes and LV dysfunction. METHODS: A retrospective chart review was conducted, including all 147 pediatric cancer survivors at our institution over 18 years of age and treated with an anthracycline. One hundred thirty-four patients who had at least one electrocardiogram (ECG) and echocardiogram were analyzed...
April 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28441822/-clinical-features-and-outcomes-of-radiofrequency-catheter-ablation-of-atrial-flutter-in-children
#12
H Jiang, X M Li, Y Zhang, H J Liu, M T Li, H Y Ge
Objective: To explore the clinical features of atrial flutter (AFL) and evaluate the efficacy of radiofrequency catheter ablation (RFCA) for AFL in children. Method: Data were collected and analyzed on 50 consecutive pediatric AFL patients (male 37/female 13) who underwent electrophysiology study and RFCA from February 2009 to November 2016 in a case observational study. The average age was (6.2±3.5) years and body weight was (23.7±13.5) kg. Heart structure was normal in 26 patients. Twenty-four patients had congenital heart disease (CHD) and among them 22 patients underwent repaired surgery before...
April 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28441820/-brief-interpretation-of-the-pediatric-and-congenital-electrophysiology-society-paces-and-the-heart-rhythm-society-hrs-expert-consensus-statement-on-the-use-of-catheter-ablation-in-children-and-patients-with-congenital-heart-disease
#13
https://www.readbyqxmd.com/read/28436586/transesophageal-and-invasive-electrophysiologic-evaluation-in-children-with-wolff-parkinson-white-pattern
#14
Serhat Koca, Feyza Aysenur Pac, Ahmet Vedat Kavurt, Serkan Cay, Ajda Mihcioglu, Dursun Aras, Serkan Topaloglu
BACKGROUND: Risk stratification for Wolff-Parkinson-White (WPW) pattern either by noninvasive or invasive tests is important to determine whether an ablation is necessary or not. The aim was to compare noninvasive tests and invasive studies in a pediatric WPW population. METHODS: A total of 71 WPW patients (median age 14 years [interquartile range, 11-16 years]; 43 male) underwent Holter monitoring, exercise stress test (EST), and transesophageal electrophysiological study (TEEPS)...
April 24, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28375940/electrophysiological-studies-to-detect-peripheral-neuropathy-in-children-treated-with-vincristine
#15
Marko Kavcic, Blaz Koritnik, Matevz Krzan, Orjana Velikonja, Tomaz Prelog, Milica Stefanovic, Maruša Debeljak, Janez Jazbec
Patients treated with vincristine predictably develop peripheral neuropathy. The aim of our study was to investigate the pattern of vincristine-induced neuropathy in children by nerve conduction studies and somatosensory-evoked potentials (SSEPs). We included data from 39 children who received vincristine for various pediatric malignancies, and we performed initial and follow-up (after a minimum of 4 doses of vincristine 1.5 mg/m) conduction studies in 27 patients and SSEPs studies in 34 patients. On follow-up the most prevalent symptoms were paresthesias (44%) and constipation (22%), and the most common neurological sign was impaired myotatic reflexes (89%)...
May 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28341476/panel-based-clinical-genetic-testing-in-85-children-with-inherited-retinal-disease
#16
Rachel L Taylor, Neil R A Parry, Stephanie J Barton, Christopher Campbell, Claire M Delaney, Jamie M Ellingford, Georgina Hall, Claire Hardcastle, Jiten Morarji, Elisabeth J Nichol, Lindsi C Williams, Sofia Douzgou, Jill Clayton-Smith, Simon C Ramsden, Vinod Sharma, Susmito Biswas, I Chris Lloyd, Jane L Ashworth, Graeme C Black, Panagiotis I Sergouniotis
PURPOSE: To assess the clinical usefulness of genetic testing in a pediatric population with inherited retinal disease (IRD). DESIGN: Single-center retrospective case series. PARTICIPANTS: Eighty-five unrelated children with a diagnosis of isolated or syndromic IRD who were referred for clinical genetic testing between January 2014 and July 2016. METHODS: Participants underwent a detailed ophthalmic examination, accompanied by electrodiagnostic testing (EDT) and dysmorphologic assessment where appropriate...
March 21, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28322026/objective-3d-surface-evaluation-of-intracranial-electrophysiologic-correlates-of-cerebral-glucose-metabolic-abnormalities-in-children-with-focal-epilepsy
#17
Jeong-Won Jeong, Eishi Asano, Vinod Kumar Pilli, Yasuo Nakai, Harry T Chugani, Csaba Juhász
To determine the spatial relationship between 2-deoxy-2[(18) F]fluoro-D-glucose (FDG) metabolic and intracranial electrophysiological abnormalities in children undergoing two-stage epilepsy surgery, statistical parametric mapping (SPM) was used to correlate hypo- and hypermetabolic cortical regions with ictal and interictal electrocorticography (ECoG) changes mapped onto the brain surface. Preoperative FDG-PET scans of 37 children with intractable epilepsy (31 with non-localizing MRI) were compared with age-matched pseudo-normal pediatric control PET data...
June 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28319875/electrophysiologic-features-of-ulnar-neuropathy-in-childhood-and-adolescence
#18
Ioannis Karakis, Wendy Liew, Heather Szelag Fournier, H Royden Jones, Basil T Darras, Peter B Kang
OBJECTIVE: To analyze patterns of nerve injury in pediatric ulnar neuropathy (PUN). METHODS: Retrospective analysis of 49 children with PUN. RESULTS: Sensory loss in digit V was the prevailing complaint (89%). Predominant localization was at the elbow (55%). Diminished ulnar SNAP was the most common abnormality (71%) with median axon loss estimate (MAXE) of 62%. Dorsal ulnar cutaneous (DUC) sensory nerve action potential (SNAP) was reduced in 55% with MAXE of 43%...
May 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28274505/limited-fluoroscopy-catheter-ablation-of-accessory-pathways-in-children
#19
Moshe Swissa, Einat Birk, Tamir Dagan, Sody Abby Naimer, Michal Fogelman, Tom Einbinder, Elchanan Bruckheimer, Rami Fogelman
BACKGROUND: Limited fluoroscopy ablation using 3D electro-anatomical system (3DS) has been used for arrhythmias in children, however it is not a common practice. We aimed to facilitate a fluoroscopy limited approach for ablation of accessory pathways (AP) in children. METHODS: Following electrophysiologic (EP) catheter placement a single dual-plane fluoroscopic image (right anterior oblique-30° and left anterior oblique-60° views) was acquired and the 3DS views were rotated to be a perfect match to the fluoroscopy...
March 5, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28273405/heart-rhythm-society-expert-consensus-statements-part-2
#20
REVIEW
Susie Sennhauser, Rishi Anand, Fred Kusumoto, Nora Goldschlager
One of the most important roles for professional societies in medicine is assembling multiple stakeholders and experts to develop documents that can help guide and define policies and strategies for best medical care. Each year the Heart Rhythm Society (HRS) develops several consensus documents that address critical clinical subjects that have been identified by input from HRS members and HRS committees. Over the past 5 years, HRS has produced documents with multiple professional societies from around the world, and although the topics chosen for exploration center around arrhythmia management, the reviews and recommendations made in the documents are important for clinical cardiologists and generalists who are not arrhythmia specialists...
March 2017: Clinical Cardiology
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