keyword
MENU ▼
Read by QxMD icon Read
search

Seborrhea

keyword
https://www.readbyqxmd.com/read/27789243/proteomic-and-transcriptomic-investigation-of-acne-vulgaris-microcystic-and-papular-lesions-insights-in-the-understanding-of-its-pathophysiology
#1
Jusal Quanico, Jean-Pascal Gimeno, Florence Nadal-Wollbold, Christiane Casas, Sandrine Alvarez-Georges, Daniel Redoulès, Anne-Marie Schmitt, Isabelle Fournier, Michel Salzet
BACKGROUND: The pathogenesis of acne vulgaris involves several phases including androgen-dependent hyper-seborrhea, colonization by Propionibacterium acnes, and inflammation. Recent investigations have shown that in fact P. acnes provokes the activation of the inflammasome present in macrophages and dendritic cells. This signaling pathway leads to excessive production of interleukin IL-1β, a proinflammatory cytokine. Nevertheless, these well-studied phenomena in acne fail to elucidate the mechanisms responsible for the appearance of different lesions...
October 24, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27778328/low-dose-oral-isotretinoin-for-moderate-to-severe-seborrhea-and-seborrheic-dermatitis-a-randomized-comparative-trial
#2
Cristhine de Souza Leão Kamamoto, Adriana Sanudo, Karime M Hassun, Ediléia Bagatin
BACKGROUND: The efficacy of low-dose oral isotretinoin in the treatment of seborrhea and seborrheic dermatitis has been poorly investigated in randomized studies. OBJECTIVES: This study was designed to determine the efficacy and safety of low-dose oral isotretinoin in the treatment of moderate to severe seborrhea and seborrheic dermatitis on the scalp and/or face. METHODS: A randomized, comparative clinical trial, using two groups, was conducted over 6 months...
October 25, 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27113551/at-10-years-of-chlormadinone-use-in-latin-america-a-review
#3
Patricio Barriga P, Nicola Ambrosi Penazzo, Marta Franco Finotti, Alfredo A Celis, Oscar Cerdas, Jorge Armando Chávez, Luis Alfredo Cuitiño, César Eduardo Fernandes, Manuel Antonio Plata, José Tirán-Saucedo, Paula Sofía Vanhauwaert
Chlormadinone acetate (CMA) is a progesterone derivative (17α-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione), first synthesized in 1961. It was used as progestin-based hormone replacement therapy; since 1999 it was first used for oral contraception combined with ethinyl estradiol (EE). CMA exerts a potent progestagenic effect, about one third higher than that observed with endogenous progesterone. CMA is also an anti-estrogen, showing no androgenic effects (at birth control dose). Unlike progesterone, it has a mild glucosteroidal effect with no anti-mineralocorticoid effect at all...
July 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/26868903/biofilm-production-and-antifungal-susceptibility-of-co-cultured-malassezia-pachydermatis-and-candida-parapsilosis-isolated-from-canine-seborrheic-dermatitis
#4
K Bumroongthai, P Chetanachan, W Niyomtham, C Yurayart, N Prapasarakul
The yeasts Malassezia (M.) pachydermatis and Candida (C.) parapsilosis are often co-isolated in case of canine seborrhea dermatitis (SD) and also are emerging as opportunistic pathogens of immunocompromised human beings. Increased information about how their relationship results in biofilm production and an antifungal response would be useful to inform treatment and control. This study was designed to investigate biofilm production derived from co-culture of M. pachydermatis and C. parapsilosis from dog skin and to determine their in vitro antifungal susceptibility...
July 1, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/26342835/possible-intermediary-role-of-ghrelin-in-seborrhea
#5
Zareie Elham, Agah Shahram, Sadeghpour Omid
Seborrhea, or oily skin, is a very common condition, especially among young people, caused by the increased secretion of sebum by sebaceous glands in the skin. Based on today's knowledge, a regulatory role of various hormones especially androgens is considered for sebaceous gland secretion; but despite significant evidences emphasis on the effects of the gastrointestinal disorders on coetaneous manifestations, the role of gastrointestinal problems in sebum secretion has not been emphasized yet. This study aimed to explain hormonal changes occurring in gastroesophageal reflux disease which may cause changes in sebaceous gland secretion so that, by explaining these communication mechanisms, common investigations between gastroenterology and dermatology can be performed to evaluate the accuracy of this hypothesis...
December 2015: Medical Hypotheses
https://www.readbyqxmd.com/read/26333057/eccrine-porocarcinoma-shares-dermoscopic-characteristics-with-eccrine-poroma-a-report-of-three-cases-and-review-of-the-published-work
#6
Tomohiro Edamitsu, Akane Minagawa, Hiroshi Koga, Hisashi Uhara, Ryuhei Okuyama
Eccrine porocarcinoma (EPC) is a rare malignant skin tumor presumably arising from the intraepidermal ductal portion of the sweat gland. EPC occasionally mimics eccrine poroma (EP), seborrhea keratosis (SK), basal cell carcinoma (BCC), pyogenic granuloma (PG) and amelanotic melanoma with its clinical appearance as a pink nodule. Dermoscopy is an invaluable technique in diagnosing skin tumors. However, few cases of EPC have been reported using dermoscopic images, and their details were not well examined. Here, we present three histopathologically proven cases of EPC and summarize their dermoscopic findings together with five previously reported cases...
March 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/26288423/correlation-of-skin-changes-with-hormonal-changes-in-polycystic-ovarian-syndrome-a-cross-sectional-study-clinical-study
#7
B Vijaya Gowri, P L Chandravathi, P S Sindhu, K Shanthi Naidu
BACKGROUND: Polycystic ovarian syndrome (PCOS) is a heterogenous collection of signs and symptoms that when gathered, form a spectrum of disorder with disturbance of reproductive, endocrine and metabolic functions. AIM: The aim of this study is to correlate the skin manifestations with hormonal changes and to know the incidence and prevalence of skin manifestations in patients with PCOS. MATERIALS AND METHODS: A total of 40 patients with PCOS were examined during 1 year time period from May 2008 P to May 2009...
July 2015: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/26229697/hyperandrogenism-insulin-resistance-acanthosis-nigricans-syndrome
#8
A H Dédjan, A Chadli, S El Aziz, A Farouqi
Introduction. Female hyperandrogenism is a frequent motive of consultation. It is revealed by hirsutism, acne or seborrhea, and disorders in menstruation cycle combined or not with virilisation signs. Several etiologies are incriminated but the hyperandrogenism-insulin resistance-acanthosis nigricans syndrome is rare. Observation. A 20-year-old girl, having had a five-year-old secondary amenorrhea. The exam revealed a patient, normotensive with a body mass index at 30 kg/m(2) and a waist measurement of 120 cm, a severe hirsutism assessed to be 29 according to Ferriman Gallwey scale, virilisation signs of male morphotype, clitoridic hypertrophy and frontal alopecia, and an acanthosis nigricans behind the neck, in the armpits and elbows...
2015: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/26142529/the-safety-and-efficacy-of-3-cannabis-seeds-extract-cream-for-reduction-of-human-cheek-skin-sebum-and-erythema-content
#9
Atif Ali, Naveed Akhtar
Escalated sebum fabrication is seen with an unattractive look and adds to the growth of acne. We aimed to investigate the efficacy and safety of 3% Cannabis seeds extract cream on human cheek skin sebum and erythema content. For this purpose, base plus 3% Cannabis seeds extract and base (control) were prepared for single blinded and comparative study. Healthy males were instructed to apply the base plus 3% Cannabis seeds extract and base twice a day to their cheeks for 12 weeks. Adverse events were observed to determine skin irritation...
July 2015: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/25914553/a-dermocosmetic-containing-bakuchiol-ginkgo-biloba-extract-and-mannitol-improves-the-efficacy-of-adapalene-in-patients-with-acne-vulgaris-result-from-a-controlled-randomized-trial
#10
Katarína Poláková, Aurélie Fauger, Michèle Sayag, Eric Jourdan
BACKGROUND: Acne vulgaris is an inflammatory disorder of the pilosebaceous unit. AIM: To confirm that BGM (bakuchiol, Ginkgo biloba extract, and mannitol) complex increases the established clinical efficacy of adapalene 0.1% gel in patients with acne. METHODS: A clinical trial was conducted in acne patients. A total of 111 subjects received adapalene 0.1% gel and BGM complex or vehicle cream for 2 months. Assessments comprised Investigator Global Assessment (IGA), global efficacy, seborrhea intensity, inflammatory and non-inflammatory lesions, and subject perception, as well as overall safety and local tolerance and quality of life...
2015: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/25625101/the-efficacy-of-oral-isotretinoin-versus-cyproterone-compound-in-female-patients-with-acne-and-the-triad-of-cutaneous-hyperandrogenism-a-randomized-clinical-trial
#11
Gita Faghihi, Kioumars Jamshidi, Nabet Tajmirriahi, Bahareh Abtahi-Naeini, Mohamadali Nilforoshzadeh, Mohamadreza Radan, Sayed Mohsen Hosseini
BACKGROUND: SAHA (Seborrhea, Acne, Hirsutism and Androgenetic Alopecia) syndrome is a dermatologic disorder, with variant response to treatment. Triad of cutaneous hyperandrogenism included nodulocystic or severe acne, female pattern hair loss and hirsutism. AIM: The aim of this study is to compare the effectiveness of isotretinoin and cyproterone compound in the treatment of nodulocystic acne, in patients with SAHA syndrome or triad of cutaneous hyperandrogenism...
2014: Advanced Biomedical Research
https://www.readbyqxmd.com/read/25476595/skin-problems-following-septorhinoplasty
#12
Eltaf A O Koc, Fuat Buyuklu, Bulent Koç, Gulsen T Demirci
OBJECTIVES/HYPOTHESIS: Septorhinoplasty is one of the most commonly performed plastic surgery procedures in the world. Studies on septorhinoplasty in the literature mainly focus on the surgical procedures and their outcomes, but the general appearance of the nose and nasal skin following surgery is also very important. STUDY DESIGN: Case-control study examining 30 septorhinoplasty patients and 20 septoplasty patients for postoperative skin conditions. RESULTS: There were significant differences identified between the septorhinoplasty group and the septoplasty group with respect to their mean preoperative Global Acne Grading System, Seborrheic Dermatitis Area Severity Index, and visual analog scores (acne, seborrhea, and ecchymosis)...
June 2015: Laryngoscope
https://www.readbyqxmd.com/read/25236322/efficacy-tolerability-impact-on-quality-of-life-and-sebostatic-activity-of-three-topical-preparations-for-the-treatment-of-mild-to-moderate-facial-acne-vulgaris
#13
Giuseppe Stinco, Fabio Piccirillo, Francesca Valent, Enzo Errichetti, Nicola DI Meo, Giusto Trevisan, Pasquale Patrone
BACKGROUND: Acne is treated according to the clinical observations and pathophysiologically relevant mechanisms, such as hyper-keratinization, seborrhea and bacterial proliferation. In mild and moderate forms of inflammatory acne, topical antimicrobials are recommended as a monotherapy or in combination with topical retinoids. The aim of this study was to compare the clinical effectiveness, tolerability, impact on quality of life and effect on sebum excretion of three antimicrobial preparations: clindamycin phosphate, benzoyl peroxide and a combination of clindamycin phosphate plus benzoyl peroxide...
June 2016: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/25129194/effects-of-hyperandrogenism-and-high-body-mass-index-on-acne-severity-in-women
#14
Sevil Alan, Erol Cenesizoglu
OBJECTIVES: To determine the association between hyperandrogenism and obesity with acne, and correlation between the severity of acne with the clinical and laboratory parameters of hyperandrogenism. METHODS: One hundred and forty-one female with acne vulgaris and 73 healthy women were included in this study. The correlation of clinical and laboratory signs of hyperandrogenism and the severity of acne was examined. RESULTS: The prevalence of overweight and obese individuals in the group with acne was determined significantly higher than the control group...
August 2014: Saudi Medical Journal
https://www.readbyqxmd.com/read/25074072/a-comparison-of-multiphasic-oral-contraceptives-containing-norgestimate-or-desogestrel-in-acne-treatment-a-randomized-trial
#15
RANDOMIZED CONTROLLED TRIAL
Unnop Jaisamrarn, Somsak Chaovisitsaree, Surasak Angsuwathana, Osot Nerapusee
OBJECTIVE: This study aimed to compare the effectiveness and safety of triphasic combined oral contraceptives (OCs) containing ethinyl estradiol (EE) and norgestimate (NGM) and biphasic combined OCs containing EE and desogestrel (DSG) in the treatment of mild to moderate acne. STUDY DESIGN: This was an investigator-blinded, randomized, parallel group trial conducted at 3 centers in Thailand. Female subjects 18-45 years old were assigned to one or the other OCs and evaluated for efficacy and safety parameters at the baseline visit and after 1, 3 and 6 months of treatment...
November 2014: Contraception
https://www.readbyqxmd.com/read/24977045/efficacy-of-cefpodoxime-with-clavulanic-acid-in-the-treatment-of-recurrent-pyoderma-in-dogs
#16
B Sudhakara Reddy, K Nalini Kumari, V Vaikunta Rao, V C Rayulu
In the present study on recurrent pyoderma, dogs with a history of more than three episodes of skin infections in a period of one year were selected. The associated conditions and (or) underlying factors revealed upon thorough investigation were demodicosis, Malassezia dermatitis, flea infestation, hypothyroidism, keratinization disorder (seborrhea), combination of Malassezia dermatitis and tick infestation, and a combination of scabies and tick infestation. Therapy was given with cefpodoxime with clavulanic acid along with appropriate simultaneous medication for the underlying associated conditions...
2014: ISRN Veterinary Science
https://www.readbyqxmd.com/read/24767186/acne-as-a-chronic-systemic-disease
#17
REVIEW
Christos C Zouboulis
Acne is the most common skin disorder. In the majority of cases, acne is a disease that changes its skin distribution and severity over time; moreover, it can be a physically (scar development) and psychologically damaging condition that lasts for years. According to its clinical characteristics, it can be defined as a chronic disease according to the World Health Organization criteria. Acne is also a cardinal component of many systemic diseases or syndromes, such as congenital adrenal hyperplasia, seborrhea-acne-hirsutism-androgenetic alopecia syndrome, polycystic ovarian syndrome, hyperandrogenism-insulin resistance-acanthosis nigricans syndrome, Apert syndrome, synovitis-acne-pustulosis-hyperostosis-osteitis syndrome, and pyogenic arthritis-pyoderma gangrenosum-acne syndrome...
May 2014: Clinics in Dermatology
https://www.readbyqxmd.com/read/24589945/parkinsonism-in-elderly-rheumatoid-arthritis-patients
#18
C Bes, B Altunrende, Ş Yılmaz Türkoğlu, N Yıldız, M Soy
OBJECTIVE: The incidences of extrapyramidal symptoms and Parkinson's disease were reported to be increased in patients with rheumatoid arthritis (RA). In this study we aimed to explore the frequency of the symptoms of Parkinsonism among RA patients older than 60 years. PATIENTS AND METHODS: 30 (6 males, 24 females) consecutive RA patients, followed at a rheumatology outpatient clinic, who were 60 years of age or older; 23 patients who were diagnosed as PD and 50 sex and age matched healthy controls were included to the study...
2014: La Clinica Terapeutica
https://www.readbyqxmd.com/read/24520755/frequency-of-prediabetes-in-women-with-polycystic-ovary-syndrome
#19
Dzemal Ibricevic, Zelija Velija Asimi
INTRODUCTION: In approximately 50-70% of all women with PCOS (Polycystic Ovarian Syndrome) may be found lower or higher degree insulin resistance, while insensitivity to insulin cells very likely contributes hyperandrogenaemia which is responsible for the symptoms and signs of PCOS. Insulin resistance, PCOS and prediabetes are linked. MATERIAL AND METHODS: This research is retrospective-prospective, clinical, comparative and descriptive. The study included 60 women with PCOS, aged 20-40 years, with no acute or chronic diseases, divided into two groups: PCOS women with elevated body weight and PCOS women with normal body weight...
2013: Medical Archives
https://www.readbyqxmd.com/read/24503019/activation-of-nrf2-in-keratinocytes-causes-chloracne-madish-like-skin-disease-in-mice
#20
Matthias Schäfer, Ann-Helen Willrodt, Svitlana Kurinna, Andrea S Link, Hany Farwanah, Alexandra Geusau, Florian Gruber, Olivier Sorg, Aaron J Huebner, Dennis R Roop, Konrad Sandhoff, Jean-Hilaire Saurat, Erwin Tschachler, Marlon R Schneider, Lutz Langbein, Wilhelm Bloch, Hans-Dietmar Beer, Sabine Werner
The transcription factor Nrf2 is a key regulator of the cellular stress response, and pharmacological Nrf2 activation is a promising strategy for skin protection and cancer prevention. We show here that prolonged Nrf2 activation in keratinocytes causes sebaceous gland enlargement and seborrhea in mice due to upregulation of the growth factor epigen, which we identified as a novel Nrf2 target. This was accompanied by thickening and hyperkeratosis of hair follicle infundibula. These abnormalities caused dilatation of infundibula, hair loss, and cyst development upon aging...
April 2014: EMBO Molecular Medicine
keyword
keyword
78219
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"