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kidney transplantation MRI

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https://www.readbyqxmd.com/read/27864568/value-of-dynamic-mri-using-the-ktrans-technique-for-assessment-of-native-kidneys-in-pre-emptive-renal-transplantation
#1
Recep Sade, Mecit Kantarci, Leyla Karaca, Aylin Okur, Hayri Ogul, Mustafa Keles, Erdem Çankaya, Arif Kursad Ayan
BACKGROUND: Different non-invasive imaging techniques such as Doppler ultrasonography and renal scintigraphy are commonly employed to assess allograft function and associated complications. However, all such methods lack sufficient specificity to discriminate between residual renal function of native kidneys. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) evaluates signal dynamics during the passage of contrast material through the renal cortex, medulla, and collecting system...
November 18, 2016: Acta Radiologica
https://www.readbyqxmd.com/read/27822324/sonographically-unusual-breast-carcinomas-2-case-reports
#2
Gozde Arslan, Levent Celik
BACKGROUND: For infiltrative breast lesions; sonography might not always be as helpful as mammography and MRI (magnetic resonance imaging). For higher sensitivity and specificity, these 3 imaging methods should be carried out together. Radiologists should be aware of the patient's history and complaints. Patients who have a specific history like a long-term drug treatment or a palpable tumour should be approached differently. CASE REPORT: We would like to present 2 cases with atypical sonographic findings...
2016: Polish Journal of Radiology
https://www.readbyqxmd.com/read/27793122/acute-pancreatitis-associated-with-everolimus-after-kidney-transplantation-a-case-report
#3
Francesco Fontana, Gianni Cappelli
BACKGROUND: Acute pancreatitis (AP) following KT is a rare and often fatal complication of the early post-transplant period. Common causative factors for AP are rare after KT; anti-rejection drugs as CyA, prednisone and MMF have been implicated, although evidence is not strong and we found no reports on possible causative role for mTOR inhibitors. CASE PRESENTATION: A 55-year-old Caucasian man with end-stage renal disease due to idiopathic membrano-prolipherative glomerulonephritis underwent single kidney transplantation (KT) from cadaveric donor...
October 28, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27777772/urothelial-carcinoma-of-donor-origin-in-a-kidney-transplant-patient
#4
Rosa M Michel Ortega, Daynna J Wolff, Cynthia A Schandl, Harry A Drabkin
BACKGROUND: Malignancy after transplantation is an uncommon multifactorial occurrence. Immunosuppression to prevent graft rejection is described as a major risk factor in malignancy development in the post-transplant state. Donor-derived malignancy is a rare reported complication. Herein, we review our patient history and discuss diagnostic strategies and the implications of immunosuppression for donor-derived malignancy. CASE PRESENTATION: This is a 69-year-old man with post-renal-transplant urothelial carcinoma determined to be of donor origin...
2016: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/27651963/an-atypical-presentation-of-a-male-with-oral-facial-digital-syndrome-type-1-related-ciliopathy
#5
Sheena Sharma, Jennifer M Kalish, Ethan M Goldberg, Francis Jeshira Reynoso, Madhura Pradhan
Background. Oral-facial-digital syndrome type 1 (OFD1) is a rare condition with X-linked dominant inheritance caused by mutations in the Cxorf5 (OFD1) gene. This gene encodes the OFD1 protein located within centrosomes and basal bodies of primary cilia. Approximately 15-50% of patients with OFD1 progress to end-stage kidney disease following development of polycystic changes within the kidneys. This condition almost always causes intrauterine lethality in males. Description of Case Diagnosis and Treatment. A Caucasian male aged 9 years and 9 months presented with increased urinary frequency, increased thirst, and decreased appetite...
2016: Case Reports in Nephrology
https://www.readbyqxmd.com/read/27636770/imaging-the-kidney-using-magnetic-resonance-techniques-structure-to-function
#6
Huda Mahmoud, Charlotte Buchanan, Susan T Francis, Nicholas M Selby
PURPOSE OF REVIEW: MRI can noninvasively assess the structure and function of the kidney in a single MRI scan session. This review summarizes recent advancements in functional renal MRI techniques, with a particular focus on clinical applications. RECENT FINDINGS: A number of MRI techniques now provide measures of relevance to the pathophysiology of kidney disease. Diffusion-weighted imaging, used in chronic kidney disease and renal transplantation, shows promise as a measure of renal fibrosis...
November 2016: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/27632553/multiparametric-functional-mri-non-invasive-imaging-of-inflammation-and-edema-formation-after-kidney-transplantation-in-mice
#7
Katja Hueper, Marcel Gutberlet, Jan Hinrich Bräsen, Mi-Sun Jang, Anja Thorenz, Rongjun Chen, Barbara Hertel, Amelie Barrmeyer, Martina Schmidbauer, Martin Meier, Sibylle von Vietinghoff, Abedalrazag Khalifa, Dagmar Hartung, Hermann Haller, Frank Wacker, Song Rong, Faikah Gueler
BACKGROUND: Kidney transplantation (ktx) in mice is used to learn about rejection and to develop new treatment strategies. Past studies have mainly been based on histological or molecular biological methods. Imaging techniques to monitor allograft pathology have rarely been used. METHODS: Here we investigated mice after isogenic and allogenic ktx over time with functional MRI with diffusion-weighted imaging (DWI) and mapping of T2-relaxation time (T2-mapping) to assess graft inflammation and edema formation...
2016: PloS One
https://www.readbyqxmd.com/read/27290710/-correlation-between-susceptibility-weighted-imaging-manifestation-and-serum-cystatin-c-for-delayed-graft-function
#8
J Sun, Z Y Xing, S N Yu, J Chen, T T Zha, M Fan, J H Ma, W Xing
OBJECTIVE: To explore the correlation between susceptibility weighted imaging (SWI) manifestation and serum cystatin C level for delayed graft function (DGF). METHODS: The conventional MRI, SWI and serum cystatin C of 27 cases with DGF in nephrotransplantation center in Third Affiliated Hospital of Suzhou University from September 2014 and August 2015 were retrospectively analyzed.By contrasting conventional MRI images of transplanted kidney in DGF, the imaging manifestations of benign tumors such as cysts and angiomyolipomas were excluded on SWI images, and then making the renal cortex as the reference, if the abnormal signal lesions were found in the transplanted kidney, the location and signal intensity would be analyzed...
June 7, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27225644/magnetoencapsulated-human-islets-xenotransplanted-into-swine-a-comparison-of-different-transplantation-sites
#9
Dian R Arifin, Steffi Valdeig, Robert A Anders, Jeff W M Bulte, Clifford R Weiss
BACKGROUND: The fate of magnetically labeled, barium-gelled alginate/protamine sulfate/alginate microcapsules (APSA magnetocapsules) following xenotransplantation was assessed by magnetic resonance imaging (MRI) and histopathology. METHODS: Magnetocapsules with and without human islets were transplanted into five different clinically accessible sites: portal vein, subcutaneous tissue, skeletal muscle, the liver and the kidney subcapsular space. The surface of APSA magnetocapsules was modified using clinical-grade heparin to mitigate an instant blood-mediated inflammatory reaction...
May 2016: Xenotransplantation
https://www.readbyqxmd.com/read/27114341/evaluation-of-renal-allografts-function-early-after-transplantation-using-intravoxel-incoherent-motion-and-arterial-spin-labeling-mri
#10
Tao Ren, Cheng-Long Wen, Li-Hua Chen, Shuang-Shuang Xie, Yue Cheng, Ying-Xin Fu, Niels Oesingmann, Andre de Oliveira, Pan-Li Zuo, Jian-Zhong Yin, Shuang Xia, Wen Shen
PURPOSE: To evaluate renal allografts function early after transplantation using intravoxel incoherent motion (IVIM) and arterial spin labeling (ASL) MRI. METHODS: This prospective study was approved by the local ethics committee, and written informed consent was obtained from all participants. A total of 82 participants with 62 renal allograft recipients (2-4weeks after kidney transplantation) and 20 volunteers were enrolled to be scanned using IVIM and ASL MRI on a 3...
September 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27057842/calcineurin-inhibitors-associated-posterior-reversible-encephalopathy-syndrome-in-solid-organ-transplantation-report-of-2-cases-and-literature-review
#11
REVIEW
Turun Song, Zhengsheng Rao, Qiling Tan, Yang Qiu, Jinpeng Liu, Zhongli Huang, Xianding Wang, Tao Lin
Posterior reversible encephalopathy syndrome (PRES) is a rare neurologic side effect of calcineurin inhibitors (CNIs) with poorly understood clinical features.We report cases of 2 patients with PRES developing after kidney transplantation and summarize PRES clinical features through a literature review.The 1st case was a 28-year-old man who received a kidney transplant from a deceased donor. Initial immunosuppressive therapy consisted of tacrolimus/mycophenolate mofetil/prednisolone. He developed headache and blurred vision with visual field loss15 days after transplantation and generalized seizures 4 days later...
April 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27039324/acute-pyelonephritis-in-transplanted-kidneys-can-diffusion-weighted-magnetic-resonance-imaging-be-useful-for-diagnosis-and-follow-up
#12
Riccardo Faletti, Maria Carla Cassinis, Marco Gatti, Jacopo Giglio, Carla Guarnaccia, Marina Messina, Laura Bergamasco, Paolo Fonio
PURPOSE: To assess reliability of diffusion-weighted magnetic resonance imaging (DW-MRI) in the management of acute pyelonephritis (APN) foci in transplanted kidneys. MATERIALS AND METHODS: In the 2012-2014 period, 24 kidney-transplanted patients underwent MR screening for clinical suspicion of APN. Two readers independently analyzed all images, establishing presence and location of APN foci. The 22 patients who were positive at the MR exam constituted the study population...
March 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/26787580/multiple-intracranial-tuberculomas-in-a-post-kidney-transplant-patient
#13
Davood Yadegarynia, Muayad A Merza, Shahnaz Sali, Zahra Sadat Seghatoleslami
Tuberculosis (TB) is a serious public health problem worldwide, particularly in developing countries. The most common presentation of TB is the pulmonary form; however, extrapulmonary manifestations are not uncommon, particularly in the immunocompromised patients. TB of the central nervous system is the most severe extrapulmonary presentation. We report a post-kidney transplant patient who had multiple ring-like lesions on contrast-enhanced magnetic resonance imaging (MRI). Based on the results of MRI and biopsy specimen, the patient was diagnosed with multiple intracranial tuberculomas...
January 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/26778459/diffusion-weighted-imaging-and-diffusion-tensor-imaging-detect-delayed-graft-function-and-correlate-with-allograft-fibrosis-in-patients-early-after-kidney-transplantation
#14
Katja Hueper, Abedalrazag A Khalifa, Jan H Bräsen, Van Dai Vo Chieu, Marcel Gutberlet, Sabine Wintterle, Frank Lehner, Nicolas Richter, Matti Peperhove, Susanne Tewes, Kristina Weber, Hermann Haller, Frank Wacker, Wilfried Gwinner, Faikah Gueler, Dagmar Hartung
PURPOSE: To combine diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) for detection of allograft dysfunction in patients early after kidney transplantation and to correlate diffusion parameters with renal function and renal histology of allograft biopsies. MATERIALS AND METHODS: Between day 4 and 11 after kidney transplantation 33 patients with initial graft function and 31 patients with delayed graft function (DGF) were examined with a 1.5T magnetic resonance imaging (MRI) scanner...
July 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/26628260/-functional-magnetic-resonance-imaging-of-the-kidneys
#15
REVIEW
R S Lanzman, M Notohamiprodjo, H J Wittsack
Interest in functional renal magnetic resonance imaging (MRI) has significantly increased in recent years. This review article provides an overview of the most important functional imaging techniques and their potential clinical applications for assessment of native and transplanted kidneys, with special emphasis on the clarification of renal tumors.
December 2015: Der Radiologe
https://www.readbyqxmd.com/read/26607205/posterior-reversible-encephalopathy-syndrome-after-kidney-transplantation-in-pediatric-recipients-two-cases
#16
Antenore Giussani, Gianluigi Ardissino, Mirco Belingheri, Robertino Dilena, Mauro Raiteri, Antonio Pasciucco, Caterina Colico, Claudio Beretta
PRES is a neuro-clinical and radiological syndrome that can result as a consequence of several different conditions including hypertension, fluid overload, and immunosuppressive treatment. Herein, we report two children who received kidney and combined liver-kidney transplantation as treatment for renal hypodysplasia associated with bilateral vesico-ureteral reflux and methylmalonic acidemia, respectively. Early after surgery (seven and 10 days), both patients presented with hypertension and seizures. The patients' immunosuppressive regimen included steroid and calcineurin inhibitors (tacrolimus and cyclosporine, respectively) and basiliximab and one with anti-IL2 receptor...
February 2016: Pediatric Transplantation
https://www.readbyqxmd.com/read/26561047/longitudinal-assessment-of-renal-perfusion-and-oxygenation-in-transplant-donor-recipient-pairs-using-arterial-spin-labeling-and-blood-oxygen-level-dependent-magnetic-resonance-imaging
#17
David J Niles, Nathan S Artz, Arjang Djamali, Elizabeth A Sadowski, Thomas M Grist, Sean B Fain
OBJECTIVES: The aims of this study were to assess renal function in kidney transplant recipients and their respective donors over 2 years using arterial spin labeling (ASL) and blood oxygen level-dependent (BOLD) magnetic resonance imaging (MRI) and to prospectively evaluate the effect of losartan on functional MRI measures in recipients. MATERIALS AND METHODS: The study included 15 matched pairs of renal transplant donors and recipients. Arterial spin labeling and BOLD MRI of the kidneys were performed on donors before transplant surgery (baseline) and on both donors and recipients at 3 months, 1 year, and 2 years after transplant...
February 2016: Investigative Radiology
https://www.readbyqxmd.com/read/26534929/imaging-panorama-in-postoperative-complications-after-liver-transplantation
#18
REVIEW
Binit Sureka, Kalpana Bansal, S Rajesh, Amar Mukund, Viniyendra Pamecha, Ankur Arora
The liver is the second most-often transplanted solid organ after the kidney, so it is clear that liver disease is a common and serious problem around the globe. With the advancements in surgical, oncological and imaging techniques, orthotopic liver transplantation has become the first-line treatment for many patients with end-stage liver disease. Ultrasound, and Doppler are the most economical and cost-effective imaging modalities for evaluating postoperative fluid collections and vascular complications. Computed tomography (CT) is used to confirm the findings of ultrasound and look for pulmonary complications...
May 2016: Gastroenterology Report
https://www.readbyqxmd.com/read/26516431/functional-assessment-of-transplanted-kidneys-with-magnetic-resonance-imaging
#19
REVIEW
Yu-Ting Wang, Ying-Chun Li, Long-Lin Yin, Hong Pu, Jia-Yuan Chen
Kidney transplantation has emerged as the treatment of choice for many patients with end-stage renal disease, which is a significant cause of morbidity and mortality. Given the shortage of clinically available donor kidneys and the significant incidence of allograft dysfunction, a noninvasive and accurate assessment of the allograft renal function is critical for postoperative management. Prompt diagnosis of graft dysfunction facilitates clinical intervention of kidneys with salvageable function. New advances in magnetic resonance imaging (MRI) technology have enabled the calculation of various renal parameters that were previously not feasible to measure noninvasively...
October 28, 2015: World Journal of Radiology
https://www.readbyqxmd.com/read/26454224/n-octanoyl-dopamine-treatment-exerts-renoprotective-properties-in-acute-kidney-injury-but-not-in-renal-allograft-recipients
#20
Sarah Klotz, Prama Pallavi, Charalambos Tsagogiorgas, Fabian Zimmer, Frank G Zöllner, Uta Binzen, Wolfgang Greffrath, Rolf-Detlef Treede, Jakob Walter, Martin C Harmsen, Bernhard K Krämer, Mathias Hafner, Benito A Yard, Simone Hoeger
BACKGROUND: N-octanoyl dopamine (NOD) treatment improves renal function when applied to brain dead donors and in the setting of warm ischaemia-induced acute kidney injury (AKI). Because it also activates transient receptor potential vanilloid type 1 (TRPV1) channels, we first assessed if NOD conveys its renoprotective properties in warm ischaemia-induced AKI via TRPV1 and secondly, if renal transplant recipients also benefit from NOD treatment. METHODS: We induced warm renal ischaemia in Lewis, wild-type (WT) and TRPV1(-/-) Sprague-Dawley (sd) rats by clamping the left renal artery for 45 min...
April 2016: Nephrology, Dialysis, Transplantation
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