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micronutrient testing

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https://www.readbyqxmd.com/read/29227176/metabolomics-approach-in-the-study-of-the-well-defined-polyherbal-preparation-zyflamend
#1
Eric D Tague, Allen K Bourdon, Amber MacDonald, Maggie S Lookadoo, Edward D Kim, Wesley M White, Paul D Terry, Shawn R Campagna, Brynn H Voy, Jay Whelan
Zyflamend is a highly controlled blend of 10 herbal extracts that synergistically impact multiple cell signaling pathways with anticancer and anti-inflammatory properties. More recently, its effects were shown to also modify cellular energetics, for example, activation of fatty acid oxidation and inhibition of lipogenesis. However, its general metabolic effects in vivo have yet to be explored. The objective of this study was to characterize the tissue specific metabolomes in response to supplementation of Zyflamend in mice, with a comparison of equivalent metabolomics data generated in plasma from humans supplemented with Zyflamend...
December 11, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29210520/supplementation-during-pregnancy-with-small-quantity-lipid-based-nutrient-supplements-or-multiple-micronutrients-compared-with-iron-and-folic-acid-increases-women-s-urinary-iodine-concentration-in-semiurban-ghana-a-randomized-controlled-trial
#2
Seth Adu-Afarwuah, Rebecca T Young, Anna Lartey, Harriet Okronipa, Per Ashorn, Ulla Ashorn, Mamane Zeilani, Kathryn G Dewey
There is little information on whether prenatal multiple micronutrient (MMN) supplements containing iodine affect women's iodine status. In the International Lipid-based Nutrient Supplements DYAD-Ghana trial, we aimed to assess women's urinary iodine concentration (UIC, μg/L) during pregnancy, as one of the planned secondary outcomes. Women (n = 1,320) <20 weeks of gestation were randomized to consume 60 mg iron and 400 μg folic acid per day (iron and folic acid [IFA]); 18 vitamins and minerals including 250 μg iodine per day (MMN); or 20 g/day of small-quantity lipid-based nutrient supplements (LNS) with the same and additional 4 vitamins and minerals as the MMN (LNS)...
December 6, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29210507/acceptability-of-multiple-micronutrient-powders-and-iron-syrup-in-bihar-india
#3
Melissa F Young, Amy Webb Girard, Rukshan Mehta, Sridhar Srikantiah, Lucas Gosdin, Purnima Menon, Usha Ramakrishnan, Reynaldo Martorell, Rasmi Avula
Nearly two thirds of young children are anaemic in Bihar, India. Paediatric iron and folic acid syrup (IFAS) and multiple micronutrient powders (MNPs) are two evidence-based interventions to prevent anaemia. Using a randomized crossover design, we examined the acceptability of IFAS versus MNPs for children 6-23 months. In a catchment area of 2 health centres in Bihar, health front-line workers (FLWs) delivered either (a) IFAS twice weekly or (b) MNPs for 1 month followed by the other supplementation strategy for 1 month to the same families (NCT02610881)...
December 6, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29204115/a-randomized-double-blind-study-assessing-changes-in-cognitive-function-in-indian-school-children-receiving-a-combination-of-bacopa-monnieri-and-micronutrient-supplementation-vs-placebo
#4
Tora Mitra-Ganguli, Soumik Kalita, Sakshi Bhushan, Con Stough, James Kean, Nan Wang, Vidhu Sethi, Anuradha Khadilkar
Several studies have indicated a chronic cognitive enhancing effect of Bacopa monnieri across different ages and cognitive impairment associated with vitamin and mineral deficiencies in children. Therefore, we investigated the effects of 4-month supplementation with a combination of B. monnieri extract and multiple micronutrients on cognitive functions in Indian school children aged 7-12 years. This was a randomized, double-blind, parallel design, single-center study in which 300 children were randomized to receive a beverage either fortified with B...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29203653/rapid-diagnostic-testing-platform-for-iron-and-vitamin-a-deficiency
#5
Zhengda Lu, Dakota O'Dell, Balaji Srinivasan, Elizabeth Rey, Ruisheng Wang, Sasank Vemulapati, Saurabh Mehta, David Erickson
Micronutrient deficiencies such as those of vitamin A and iron affect a third of the world's population with consequences such as night blindness, higher child mortality, anemia, poor pregnancy outcomes, and reduced work capacity. Many efforts to prevent or treat these deficiencies are hampered by the lack of adequate, accessible, and affordable diagnostic methods that can enable better targeting of interventions. In this work, we demonstrate a rapid diagnostic test and mobile enabled platform for simultaneously quantifying iron (ferritin), vitamin A (retinol-binding protein), and inflammation (C-reactive protein) status...
December 4, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29199453/composition-of-legume-soaking-water-and-emulsifying-properties-in-gluten-free-bread
#6
San Huang, Yuling Liu, Weihan Zhang, Kylie J Dale, Silu Liu, Jingnan Zhu, Luca Serventi
Soaking of legumes results in the loss of macronutrients, micronutrients and phytochemicals. Fibre, protein and phytochemicals found in legumes exert emulsifying activity that may improve the structure and texture of gluten-free bread. The legume soaking water of haricot beans, garbanzo chickpeas, whole green lentils, split yellow peas and yellow soybeans were tested in this study for functional properties and use as food ingredients. Composition, physicochemical properties and effect on the quality of gluten-free bread were determined for each legume soaking water...
January 1, 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/29188854/short-term-impact-of-a-combined-nutraceutical-on-cognitive-function-perceived-stress-and-depression-in-young-elderly-with-cognitive-impairment-a-pilot-double-blind-randomized-clinical-trial
#7
A F Cicero, M Bove, A Colletti, M Rizzo, F Fogacci, M Giovannini, C Borghi
BACKGROUND: The prevalence of senile dementia is increasing worldwide, especially in the developed countries. Nevertheless, drug therapy isn't often enough to treat this condition. Researchers are evaluating the possible impact of a preventive approach, based on an improvement of lifestyle and the intake of micronutrients. Moreover, there is an increasing interest for combined nutraceuticals that can act as memory and learning enhancers, with a significant and beneficial potential on the cognitive disorders...
2017: Journal of Prevention of Alzheimer's Disease
https://www.readbyqxmd.com/read/29187063/nutrition-deficiencies-in-children-with-intestinal-failure-receiving-chronic-parenteral-nutrition
#8
Shweta S Namjoshi, Sarah Muradian, Hannah Bechtold, Laurie Reyen, Robert S Venick, Elizabeth A Marcus, Jorge H Vargas, Laura J Wozniak
BACKGROUND: Home parenteral nutrition (PN) is a lifesaving therapy for children with intestinal failure (IF). Our aims were to describe the prevalence of micronutrient deficiencies (vitamin D, zinc, copper, iron, selenium) in a diverse population of children with IF receiving PN and to identify and characterize risk factors associated with micronutrient deficiencies, including hematologic abnormalities. METHODS: Data were collected on 60 eligible patients through retrospective chart review between May 2012 and February 2015...
February 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29173121/fueling-for-performance
#9
Jeffrey R Bytomski
CONTEXT: Proper nutrition is crucial for an athlete to optimize his or her performance for training and competition. Athletes should be able to meet their dietary needs through eating a wide variety of whole food sources. EVIDENCE ACQUISITION: PubMed was searched for relevant articles published from 1980 to 2016. STUDY DESIGN: Clinical review. LEVEL OF EVIDENCE: Level 4. RESULTS: An athlete should have both daily and activity-specific goals for obtaining the fuel necessary for successful training...
November 1, 2017: Sports Health
https://www.readbyqxmd.com/read/29152234/comparison-of-measured-and-predicted-energy-density-of-an-oral-care-chew-for-dogs
#10
Danielle Nuttall, Richard Butterwick, Katja Strauhs, Phil McGenity
The dog chew studied here is a starch-based, twin-screw cooker extruded dog care and treat (C&T) product with oral health benefits. The manufacturing process and nutrient profile of such products are markedly different from those of main meal pet foods. Predicted metabolisable energy (PME) in pet food is calculated using equations derived from main meal feeding studies so it is unclear whether these equations can be applied to C&T products. The present study aimed to directly measure metabolisable energy (ME) content of the dog chew in dogs and compare with calculated PME...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29143707/effect-of-multi-micronutrient-fortified-rice-on-cognitive-performance-depends-on-premix-composition-and-cognitive-function-tested-results-of-an-effectiveness-study-in-cambodian-schoolchildren
#11
Marion Fiorentino, Marlène Perignon, Khuov Kuong, Richard de Groot, Megan Parker, Kurt Burja, Marjoleine A Dijkhuizen, Sek Sokhom, Chhoun Chamnan, Jacques Berger, Frank T Wieringa
OBJECTIVE: Even though current policy is strongly focused on the crucial first '1000 days', it might be still possible to enhance cognitive function during the pre-adolescent and adolescent years by improving micronutrient status. In Cambodia, nutritional status is poor. Provision of rice fortified with micronutrients through a school meal programme (SMP) could be a cost-effective strategy to help improve health and school performance. The present study aimed to evaluate the effect of three different micronutrient-fortified rice formulations on cognitive function in Cambodian children...
November 16, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29137512/microfinance-institutions-successful-delivery-of-micronutrient-powders-a-randomized-trial-in-rural-haiti
#12
Aaron Baum, Wesly Elize, Florence Jean-Louis
Globally, two-thirds of child deaths could be prevented by increased provision of health interventions such as vaccines, micronutrient supplements, and water purification tablets. We report the results from a randomized controlled trial in Haiti during 2012 that tested whether microfinance institutions-which reach 200 million households worldwide-can effectively deliver health products. These institutions provide loans to underserved entrepreneurs, primarily poor women in rural areas. In the intervention group, micronutrient powders to improve the nutrition of young children were distributed at regularly occurring microfinance meetings by a trained borrower...
November 2017: Health Affairs
https://www.readbyqxmd.com/read/29123343/multiple-nutritional-deficiencies-in-cerebral-palsy-compounding-physical-and-functional-impairments
#13
P G Hariprasad, K E Elizabeth, Mathew J Valamparampil, D Kalpana, T S Anish
Introduction: Cerebral palsy (CP) refers to a spectrum of disorders causing physical and intellectual morbidity. Macro and micro nutrient deficiencies often contribute to the subnormal physical and mental capabilities of them. Objectives: To assess the growth, nutritional status, physical and functional ability and quality of life in cerebral palsy children and to determine any relation with their gross motor and functional capabilities. Method: The study was conducted at a Tertiary Care Centre, with the participants in the age group 1-16 years...
October 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29120789/laser-induced-breakdown-spectroscopy-libs-for-rapid-analysis-of-ash-potassium-and-magnesium-in-gluten-free-flours
#14
Maria Markiewicz-Keszycka, Maria P Casado-Gavalda, Xavier Cama-Moncunill, Raquel Cama-Moncunill, Yash Dixit, Patrick J Cullen, Carl Sullivan
Gluten free (GF) diets are prone to mineral deficiency, thus effective monitoring of the elemental composition of GF products is important to ensure a balanced micronutrient diet. The objective of this study was to test the potential of laser-induced breakdown spectroscopy (LIBS) analysis combined with chemometrics for at-line monitoring of ash, potassium and magnesium content of GF flours: tapioca, potato, maize, buckwheat, brown rice and a GF flour mixture. Concentrations of ash, potassium and magnesium were determined with reference methods and LIBS...
April 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29116560/preoperative-and-postoperative-assessments-of-biochemical-parameters-in-patients-with-severe-obesity-undergoing-laparoscopic-sleeve-gastrectomy
#15
Deborah M Gregory, Laurie K Twells, Kendra K Lester, William K Midodzi, Mette Rode Pedersen, David Pace, Chris Smith, Darrell Boone, Edward W Randell, Christopher S Kovacs
BACKGROUND: The study aim was to determine the prevalence of abnormal serum biochemistries associated with micronutrient deficiencies before and after laparoscopic sleeve gastrectomy (LSG). METHODS: Two hundred and one patients had LSG surgery between May 2011 and May 2014. Using a prospective cohort study design, data were collected on ferritin, hemoglobin (Hgb), mean cell volume (MCV), calcium, albumin, 25-hydroxyvitamin D (25-OH-D), PTH, and vitamin B12 with follow-up of 75...
November 8, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29070548/excess-iron-considerations-related-to-development-and-early-growth
#16
REVIEW
Marianne Wessling-Resnick
What effects might arise from early life exposures to high iron? This review considers the specific effects of high iron on the brain, stem cells, and the process of erythropoiesis and identifies gaps in our knowledge of what molecular damage may be incurred by oxidative stress that is imparted by high iron status in early life. Specific areas to enhance research on this topic include the following: longitudinal behavioral studies of children to test associations between iron exposures and mood, emotion, cognition, and memory; animal studies to determine epigenetic changes that reprogram brain development and metabolic changes in early life that could be followed through the life course; and the establishment of human epigenetic markers of iron exposures and oxidative stress that could be monitored for early origins of adult chronic diseases...
December 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29069444/grain-yield-and-quality-responses-of-wheat-expressing-a-barley-sucrose-transporter-to-combined-climate-change-factors
#17
Heiko Weichert, Petra Högy, Isabel Mora-Ramirez, Jörg Fuchs, Kai Eggert, Peter Koehler, Winfriede Weschke, Andreas Fangmeier, Hans Weber
Crop yield stability must be ensured under future climate conditions such as elevated CO 2 and high temperatures. We tested 'HOSUT', a winter wheat line expressing a grain-targeted sucrose transporter of barley in response to combinations of CO 2 enrichment, a heat wave, and high nitrogen fertilization. Compared with wild-type Certo, HOSUT had a superior performance for grain yield, aboveground biomass, and ears per plant, obviously due to transgene activity in developing grains and young vegetative sinks. HOSUT grains were larger and contained more endosperm cells...
October 21, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29067348/lower-brain-and-blood-nutrient-status-in-alzheimer-s-disease-results-from-meta-analyses
#18
REVIEW
Martijn C de Wilde, Bruno Vellas, Elodie Girault, Aysun Cetinyurek Yavuz, John W Sijben
INTRODUCTION: Alzheimer's disease (AD) patients are at risk of nutritional insufficiencies because of physiological and psychological factors. Recently, we showed the results of the meta-analyses indicating lower plasma levels of vitamins A, B12, C, E, and folate in AD patients compared with cognitively intact elderly controls (controls). Now, additional and more extensive literature searches were performed selecting studies which compare blood and brain/cerebrospinal fluid (CSF) levels of vitamins, minerals, trace elements, micronutrients, and fatty acids in AD patients versus controls...
September 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29027975/dietary-supplement-use-during-preconception-the-australian-longitudinal-study-on-women-s-health
#19
Elle McKenna, Alexis Hure, Anthony Perkins, Ellie Gresham
Worldwide, dietary supplement use among reproductive aged women is becoming increasingly common. The aim of this study was to investigate dietary supplement use among Australian women during preconception. Self-reported data were collected prospectively for the Australian Longitudinal Study on Women's Health (ALSWH). The sample included 485 women aged 31-36 years, with supplement data, classified as preconception when completing Survey 5 of the ALSWH in 2009. Frequency and contingency tables were calculated and Pearson's chi-square test for associations between demographic variables and supplementation status was performed...
October 13, 2017: Nutrients
https://www.readbyqxmd.com/read/29025632/modifiers-of-the-effect-of-maternal-multiple-micronutrient-supplementation-on-stillbirth-birth-outcomes-and-infant-mortality-a-meta-analysis-of-individual-patient-data-from-17-randomised-trials-in-low-income-and-middle-income-countries
#20
Emily R Smith, Anuraj H Shankar, Lee S-F Wu, Said Aboud, Seth Adu-Afarwuah, Hasmot Ali, Rina Agustina, Shams Arifeen, Per Ashorn, Zulfiqar A Bhutta, Parul Christian, Delanjathan Devakumar, Kathryn G Dewey, Henrik Friis, Exnevia Gomo, Piyush Gupta, Pernille Kæstel, Patrick Kolsteren, Hermann Lanou, Kenneth Maleta, Aissa Mamadoultaibou, Gernard Msamanga, David Osrin, Lars-Åke Persson, Usha Ramakrishnan, Juan A Rivera, Arjumand Rizvi, H P S Sachdev, Willy Urassa, Keith P West, Noel Zagre, Lingxia Zeng, Zhonghai Zhu, Wafaie W Fawzi, Christopher R Sudfeld
BACKGROUND: Micronutrient deficiencies are common among women in low-income and middle-income countries. Data from randomised trials suggest that maternal multiple micronutrient supplementation decreases the risk of low birthweight and potentially improves other infant health outcomes. However, heterogeneity across studies suggests influence from effect modifiers. We aimed to identify individual-level modifiers of the effect of multiple micronutrient supplements on stillbirth, birth outcomes, and infant mortality in low-income and middle-income countries...
November 2017: Lancet Global Health
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