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https://www.readbyqxmd.com/read/28926722/innovation-in-care-for-individuals-with-cognitive-impairment-can-reimbursement-policy-spread-best-practices
#1
Soo Borson, Joshua Chodosh, Cyndy Cordell, Beth Kallmyer, Malaz Boustani, Anna Chodos, Jatin K Dave, Lisa Gwyther, Susan Reed, David B Reuben, Stephen Stabile, Monica Willis-Parker, William Thies
There is now an unprecedented opportunity to improve the care of the over 5 million people who are living with Alzheimer's disease and related dementias and many more with cognitive impairment due to brain injury, systemic diseases, and other causes. The introduction of a new Medicare care planning benefit-long sought openly by advocacy organizations and clinicians and badly needed by patients and families-could greatly improve health care quality, but only if widely and fully implemented. We describe the components of this new benefit and its promise of better clinical care, as well as its potential to create a new platform for clinical and health outcomes research...
September 16, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28926565/a-snp-panel-and-online-tool-for-checking-genotype-concordance-through-comparing-qr-codes
#2
Yonghong Du, Joshua S Martin, John McGee, Yuchen Yang, Eric Yi Liu, Yingrui Sun, Matthias Geihs, Xuejun Kong, Eric Lingfeng Zhou, Yun Li, Jie Huang
In the current precision medicine era, more and more samples get genotyped and sequenced. Both researchers and commercial companies expend significant time and resources to reduce the error rate. However, it has been reported that there is a sample mix-up rate of between 0.1% and 1%, not to mention the possibly higher mix-up rate during the down-stream genetic reporting processes. Even on the low end of this estimate, this translates to a significant number of mislabeled samples, especially over the projected one billion people that will be sequenced within the next decade...
2017: PloS One
https://www.readbyqxmd.com/read/28926388/opportunistic-use-of-ct-imaging-for-osteoporosis-screening-and-bone-density-assessment-a-qualitative-systematic-review
#3
Elizabeth B Gausden, Benedict U Nwachukwu, Joseph J Schreiber, Dean G Lorich, Joseph M Lane
BACKGROUND: The purpose of this study was to determine the clinical opportunities for the use of computed tomography (CT) imaging for inferring bone quality and to critically analyze the correlation between dual x-ray absorptiometry (DXA) and diagnostic CT as reported in the literature. METHODS: A systematic review of the MEDLINE database was performed in February 2016 using the PubMed interface. The inclusion criteria were English language, studies performed using living human subjects, studies pertaining to orthopaedics, use of conventional diagnostic CT scans, studies that measured cancellous bone, and studies that reported Hounsfield unit (HU) measurements directly rather than a computed bone mineral density...
September 20, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28926299/evidence-based-medicine-in-otolaryngology-part-6-patient-reported-outcomes-in-clinical-practice
#4
Thomas L Carroll, Stella E Lee, Robin Lindsay, Drew Locandro, Gregory W Randolph, Jennifer J Shin
The assessment of patient-reported outcome measures (PROMs) in the outpatient setting is gaining momentum in clinical and research venues. Implementing this data capture into one's practice, however, is not a one-size-fits-all venture, and it is critical to determine when, how, and where to include these patient-centered assessments. This installment of the "Evidence-Based Medicine in Otolaryngology" series provides insight into the implementation process and experiences with successful incorporation of PROMs into clinical practice...
September 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28926013/insights-for-the-assessment-of-the-economic-impact-of-endemic-diseases-specific-adaptation-of-economic-frameworks-using-the-case-of-bovine-viral-diarrhoea
#5
A W Stott, G J Gunn
Generic frameworks for the economic analysis of farm animal disease are now well established. The paper, therefore, uses bovine viral diarrhoea (BVD) as an example to explore how these frameworks need to be adapted to fit the characteristics of a particular disease and the specific objectives of the analysis. In the case of BVD, given the relative strength of tests available to correctly identify virus-positive animals, thus enabling them to be culled, the emphasis has been on cost-benefit analysis of regional and national certification/eradication schemes...
April 2017: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/28925941/cold-atmospheric-plasma-in-the-treatment-of-osteosarcoma
#6
REVIEW
Denis Gümbel, Sander Bekeschus, Nadine Gelbrich, Matthias Napp, Axel Ekkernkamp, Axel Kramer, Matthias B Stope
Human osteosarcoma (OS) is the most common primary malignant bone tumor occurring most commonly in adolescents and young adults. Major improvements in disease-free survival have been achieved by implementing a combination therapy consisting of radical surgical resection of the tumor and systemic multi-agent chemotherapy. However, long-term survival remains poor, so novel targeted therapies to improve outcomes for patients with osteosarcoma remains an area of active research. This includes immunotherapy, photodynamic therapy, or treatment with nanoparticles...
September 19, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28925890/the-use-of-hemodynamic-and-cerebral-monitoring-to-study-pharmacodynamics-in-neonates
#7
A Smits, L Thewissen, A Dereymaeker, E Dempsey, A Caicedo, Gunnar Naulaers
BACKGROUND: Drugs acting on the cardiovascular and central nervous system often display relatively fast clinical responses, which may differ in neonates compared to children and adults. Introduction of bedside monitoring tools might be of additional value in the pharmacodynamic (PD) assessment of such drugs in neonates. METHODS: We aim to provide an overview of the frequently used monitoring tools to assess drug effects on the hemodynamic status as well as the cerebral circulation, oxygenation and cerebral metabolism in neonates...
September 18, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28925749/cardiac-telerehabilitation-a-novel-cost-efficient-care-delivery-strategy-that-can-induce-long-term-health-benefits
#8
Ines Frederix, Francesca Solmi, Massimo F Piepoli, Paul Dendale
Background Finding innovative and cost-efficient care strategies that induce long-term health benefits in cardiac patients constitutes a big challenge today. The aim of this Telerehab III follow-up study was to assess whether a 6-month additional cardiac telerehabilitation programme could induce long-term health benefits and remain cost-efficient after the tele-intervention ended. Methods and results A total of 126 cardiac patients first completed the multicentre, randomised controlled telerehabilitation trial (Telerehab III, time points t0 to t1)...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28925378/spectroscopically-forbidden-infra-red-emission-in-au-vertical-graphene-hybrid-nanostructures
#9
A K Sivadasan, Santanu Parida, Subrata Ghosh, Ramanathaswamy Pandian, Sandip Dhara
Implementation of Au nanoparticles (NPs) is a subject for frontier plasmonic research due to its fascinating optical properties. Herein, the present study deals with plasmonic assisted emission properties of Au NPs-vertical graphene (VG) hybrid nanostructures. The influence of effective polarizability of Au NPs on the surface enhanced Raman scattering and luminescence properties is investigated. In addition, a remarkable infra-red (IR) emission in the hybrid nanostructures is observed and interpreted on the basis of intra-band transitions in Au NPs...
September 19, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28925372/an-automatic-algorithm-for-blink-artifact-suppression-based-on-iterative-template-matching-application-to-single-channel-recording-of-cortical-auditory-evoked-potentials
#10
Joaquin T Valderrama, Angel de la Torre, Bram Van Dun
Artifact reduction in electroencephalogram (EEG) signals is usually necessary to carry out data analysis appropriately. Despite the large amount of denoising techniques available with a multichannel setup, there is a lack of efficient algorithms that remove (not only detect) blink-artifacts from a single channel EEG, which is of interest in many clinical and research applications. This paper describes and evaluates the Iterative Template Matching and Suppression (ITMS), a new method proposed for detecting and suppressing the artifact associated with the blink activity from a single channel EEG...
September 19, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28924619/breath-holding-endurance-stability-over-time-and-relationship-with-self-assessed-persistence
#11
Daisy G Y Thompson-Lake, Richard De La Garza Ii, Peter Hajek
Breath holding (BH) endurance has been suggested as a measure of the distress tolerance that could predict the outcome of attempts to implement behavior changes, such as stopping smoking or illicit substance use. It is not known however, to what degree BH endurance is a variable trait that may vary depending on situational context, or a stable state characteristic. We measured BH in two groups of participants at baseline and 22 and 89 days (N = 62 and N = 41) post-baseline and in a third group at multiple times points across a 5-week period (N = 44)...
September 2017: Heliyon
https://www.readbyqxmd.com/read/28924330/manufacturing-data-analytics-using-a-virtual-factory-representation
#12
Sanjay Jain, Guodong Shao, Seung-Jun Shin
Large manufacturers have been using simulation to support decision-making for design and production. However, with the advancement of technologies and the emergence of big data, simulation can be utilised to perform and support data analytics for associated performance gains. This requires not only significant model development expertise, but also huge data collection and analysis efforts. This paper presents an approach within the frameworks of Design Science Research Methodology and prototyping to address the challenge of increasing the use of modelling, simulation and data analytics in manufacturing via reduction of the development effort...
2017: International Journal of Production Economics
https://www.readbyqxmd.com/read/28923814/new-method-for-real-time-influenza-surveillance-in-primary-care-a-wisconsin-research-and-education-network-wren-supported-study
#13
Jonathan L Temte, Shari Barlow, Amber Schemmel, Emily Temte, David L Hahn, Erik Reisdorf, Peter Shult, John Tamerius
INTRODUCTION: The goal of public health infectious disease surveillance systems is to provide accurate laboratory results in near-real time. When it comes to influenza surveillance, most current systems are encumbered with inherent delays encountered in the real-life chaos of medical practice. To combat this, we implemented and tested near-real-time surveillance using a rapid influenza detection test (RIDT) coupled with immediate, wireless transmission of results to public health entities...
September 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28923810/an-innovative-community-based-model-for-improving-preventive-care-in-rural-counties
#14
Zsolt J Nagykaldi, Dewey Scheid, Daniel Zhao, Bhawani Mishra, Tracy Greever-Rice
OBJECTIVE: This quasi-experimental pilot study aimed to implement and evaluate a sustainable, rural community-based patient outreach model for preventive care provided through primary care practices (PCPs) located in a rural county in Oklahoma. A Wellness Coordinator (WC) working with PCPs, the county health department, the county hospital, and a health information exchange (HIE) organization helped county residents receive evidence-based preventive services. METHODS: The WC used a community wellness registry connected to electronic medical records via HIE and called patients at the county level based on PCP-prioritized and tailored protocols...
September 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28923806/improving-the-health-of-patients-and-communities-evolving-practice-based-research-pbr-and-collaborations
#15
Kevin Fiscella
This issue illustrates how research from practice-based research networks has evolved to span a spectrum from improving patient-level care and practice quality to improving health within local and global communities. Articles address patient-level improvements (a biomarker for cardiovascular disease progression, late-onset anorexia nervosa, complementary health approaches used by patients, and patient preferences related to antibiotics for acute respiratory infections); practice-level improvements (selection of types of fecal immunochemical tests, practice facilitation, practice registry implementation, community-based outreach, and bidirectional texting); and community-level improvements (primary care-public health partnership, influenza surveillance, and establishing family medicine training abroad)...
September 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28923739/droplet-impact-on-superhydrophobic-surfaces-fully-decorated-with-cylindrical-macrotextures
#16
Mehran Abolghasemibizaki, Reza Mohammadi
HYPOTHESIS: Impacting on a superhydrophobic surface, water droplet spreads to a pancake shape and then retracts and bounces off. Although the collision time is mostly in the order of couple of 10ms for millimetric droplets, researchers have shown recently that decorating the superhydrophobic surface with a single macrotexture or intersecting ridge reduces this contact time if the droplet hits the texture or the intersection exactly in the center. Hence, covering the surface with ridges should address this hitting point restriction...
September 8, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28923702/zinc-oxide-nanoparticles-synthesis-antiseptic-activity-and-toxicity-mechanism
#17
REVIEW
A Król, P Pomastowski, K Rafińska, V Railean-Plugaru, B Buszewski
Zinc oxide (ZnO), as a material with attractive properties, has attracted great interest worldwide, particularly owing to the implementation of the synthesis of nano-sized particles. High luminescent efficiency, a wide band gap (3.36eV), and a large exciton binding energy (60meV) has triggered intense research on the production of nanoparticles using different synthesis methods and on their future applications. ZnO nanomaterials can be used in industry as nano-optical and nano-electrical devices, in food packaging and in medicine as antimicrobial and antitumor agents...
August 26, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28923500/priorities-for-closing-the-evidence-practice-gaps-in-post-stroke-aphasia-rehabilitation-a-scoping-review
#18
REVIEW
Kirstine Shrubsole, Linda Worrall, Emma Power, Denise A O'Connor
OBJECTIVE: To identify implementation priorities for post-stroke aphasia management relevant to the Australian healthcare context. DATA SOURCES: Using systematized searches of databases (CINAHL, Medline), guideline and stroke websites, and other sources, evidence was identified and extracted for seven implementation criteria for 13 topic areas relevant to aphasia management. These seven priority-setting criteria were identified in the implementation literature; strength of the evidence; current evidence-practice gap; clinician preference; client preference; modifiability; measurability; and health impact...
September 15, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28923200/sleep-and-obesity-risk-in-adults-possible-mechanisms-contextual-factors-and-implications-for-research-intervention-and-policy
#19
REVIEW
Michael A Grandner
Obesity is a major public health problem among US adults. Insufficient sleep and sleep disorders are prevalent and may contribute to the public health problem of obesity. This review addresses several key questions regarding sleep and obesity in adults, including the following: (1) What constitutes adequate sleep in adults? (2) What are the consequences of inadequate sleep in adults? (3) What factors influence sleep in adults? (4) How can adults improve their sleep? (5) How can we implement these in adults? (6) How can these issues be addressed in future research and policy decisions? Although a comprehensive review of all of these is beyond the scope of this article, this review brings these concepts together toward a discussion of the role of sleep in the health of US adults...
October 2017: Sleep Health
https://www.readbyqxmd.com/read/28923154/activity-during-learning-and-the-nonlinear-differentiation-of-experience
#20
Yuri I Alexandrov, Andrei K Krylov, Karina R Arutyunova
Walter Freeman's work emphasises the role of individual activity and intentionality as opposed to the traditional stimulus-reaction view and the machine metaphor. The results of our computer modeling studies suggest the nonlinear dynamics of experience emerging from perception-action cycles. We consider the perception-action cycle as a behavioral continuum of anticipated outcomes of actions. Neuroscientific research shows that each behavioral act is based on the activity of behaviorally specialized neurons distributed across the brain...
October 2017: Nonlinear Dynamics, Psychology, and Life Sciences
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