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Appropriateness criteria

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https://www.readbyqxmd.com/read/29350335/tools-for-assessment-of-the-appropriateness-of-prescribing-and-association-with-patient-related-outcomes-a-systematic-review
#1
REVIEW
Nashwa Masnoon, Sepehr Shakib, Lisa Kalisch-Ellett, Gillian E Caughey
BACKGROUND: There are tools and criteria in the literature aimed at distinguishing between appropriate and inappropriate medicines use. However, many have not been externally validated with regard to patient-related outcomes, potentially limiting their use in clinical practice. OBJECTIVES: The aim of the study was to conduct a systematic review to summarise (1) available prescribing appropriateness assessment tools and criteria, and (2) their associations with patient-related outcomes (external validity)...
January 19, 2018: Drugs & Aging
https://www.readbyqxmd.com/read/29348371/-neuroinflammation-in-the-brain-of-patients-with-myalgic-encephalomyelitis-chronic-fatigue-syndrome
#2
Yasuhito Nakatomi, Hirohiko Kuratsune, Yasuyoshi Watanabe
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by chronic, profound, disabling, and unexplained fatigue; cognitive impairment; and chronic widespread pain. By using positron emission tomography, our study demonstrated neuroinflammation in the brain of patients with ME/CFS. Neuroinflammation was found to be widespread in the brain areas of the patients with ME/CFS and was associated with the severity of their neuropsychological symptoms. The ongoing research would lead to the establishment of objective diagnostic criteria and development of an appropriate therapy...
January 2018: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29345967/reclassifying-acute-respiratory-distress-syndrome
#3
Giorgia Maiolo, Francesca Collino, Francesco Vasques, Francesca Rapetti, Tommaso Tonetti, Federica Romitti, Massimo Cressoni, Davide Chiumello, Onnen Mörer, Peter Herrmann, Tim Friede, Michael Quintel, Luciano Gattinoni
RATIONALE: The ratio of PaO2 to FiO2 (P/F) defines ARDS severity and suggests appropriate therapies. OBJECTIVES: We investigated 1) whether a 150 mmHg P/F threshold within the range of moderate ARDS (100-200 mmHg) would define two, more homogeneous subgroups, 2) which criteria led the clinicians to apply ECMO in severe ARDS. Methods & Measurements: At 150 mmHg P/F threshold, moderate patients were split in mild-moderate (n=50) and moderate-severe (n=55). Severe ARDS patients (FiO2 not available in 3 patients ) were split in higher (n=63) and lower-FiO2 (n=18) at 80% FiO2 threshold...
January 18, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29345556/positional-differences-in-elite-basketball-selecting-appropriate-training-load-measures
#4
Luka Svilar, Julen Castellano, Igor Jukic, David Casamichana
PURPOSE: The purpose of this paper was to study the structure of interrelationships among external training load measures and how these vary among different positions in elite basketball. METHODS: Eight external variables of jumping (JUMP), acceleration (ACC), deceleration (DEC) and change of direction (COD), and two internal load variables (RPE and sRPE) were collected from 13 professional players with 300 session records. Three playing positions were considered: guards (n=4), forwards (n=4) and centers (n=5)...
January 18, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29344838/association-between-human-brucellosis-and-adverse-pregnancy-outcome-a-cross-sectional-population-based-study
#5
Nesrin Ghanem-Zoubi, Silvia Pessah Eljay, Emilia Anis, Mical Paul
To investigate the association between the incidence of human brucellosis (HB) and adverse pregnancy outcomes (APOs), a population-based, cross-sectional aggregate data study was conducted in Israel between 2010 and 2014. HB-endemic localities were matched by ethnicity, population size and socioeconomic status to localities with a low incidence of HB. We compared APO rates in high-incidence vs low-incidence localities. The primary outcome was intrauterine fetal demise (IUFD). Secondary outcomes were premature birth (less than 37 weeks), early or threatened labour and poor fetal growth...
January 17, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29344619/acoustic-analysis-of-voice-in-singers-a-systematic-review
#6
Dhanshree R Gunjawate, Rohit Ravi, Rajashekhar Bellur
Purpose: Singers are vocal athletes having specific demands from their voice and require special consideration during voice evaluation. Presently, there is a lack of standards for acoustic evaluation in them. The aim of the present study was to systematically review the available literature on the acoustic analysis of voice in singers. Method: A systematic review of studies on acoustic analysis of voice in singers (PubMed/MEDLINE, CINAHL, Scopus, ProQuest, Cochrane, Ovid, Science Direct, and Shodhganga) was carried out...
January 17, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29343236/barriers-to-timely-diagnosis-of-interstitial-lung-disease-in-the-real-world-the-intensity-survey
#7
Gregory P Cosgrove, Pauline Bianchi, Sherry Danese, David J Lederer
BACKGROUND: The diagnosis of idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases (ILD) presents significant clinical challenges. To gain insights regarding the diagnostic experience of patients with ILD and to identify potential barriers to a timely and accurate diagnosis, we developed an online questionnaire and conducted a national survey of adults with a self-reported diagnosis of ILD. METHODS: A pre-specified total of 600 subjects were recruited to participate in a 40-question online survey...
January 17, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29342070/an-evaluation-of-industry-relationships-among-contributors-to-aaos-clinical-practice-guidelines-and-appropriate-use-criteria
#8
Jake X Checketts, Courtney Cook, Matt Vassar
BACKGROUND: A long-standing relationship between orthopaedic surgeons and industry has made financial conflicts of interest a concerning issue. Research supports that financial conflicts of interest can influence both medical research and clinical practice. Financial conflicts of interest may also influence clinical practice guideline recommendations and their corresponding appropriate use criteria. Because of the influential nature of these guidelines, it is imperative that care be taken to minimize bias during guideline development...
January 17, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29341895/prenatal-paracetamol-exposure-and-child-neurodevelopment-a-review
#9
REVIEW
Ann Z Bauer, David Kriebel, Martha R Herbert, Carl-Gustaf Bornehag, Shanna H Swan
BACKGROUND: The non-prescription medication paracetamol (acetaminophen, APAP) is currently recommended as a safe pain and fever treatment during pregnancy. However, recent studies suggest a possible association between APAP use in pregnancy and offspring neurodevelopment. OBJECTIVES: To conduct a review of publications reporting associations between prenatal APAP use and offspring neurodevelopmental outcomes. METHODS: Relevant sources were identified through a key word search of multiple databases (Medline, CINAHL, OVID and TOXNET) in September 2016...
January 13, 2018: Hormones and Behavior
https://www.readbyqxmd.com/read/29339348/evaluation-criteria-of-noninvasive-telemonitoring-for-patients-with-heart-failure-systematic-review
#10
REVIEW
Troskah Farnia, Marie-Christine Jaulent, Olivier Steichen
BACKGROUND: Telemonitoring can improve heart failure (HF) management, but there is no standardized evaluation framework to comprehensively evaluate its impact. OBJECTIVE: Our objectives were to list the criteria used in published evaluations of noninvasive HF telemonitoring projects, describe how they are used in the evaluation studies, and organize them into a consistent scheme. METHODS: Articles published from January 1990 to August 2015 were obtained through MEDLINE, Web of Science, and EMBASE...
January 16, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29338806/cancer-pain-management-needs-and-perspectives-of-patients-from-chinese-backgrounds-a-systematic-review-of-the-chinese-and-english-literature
#11
Xiangfeng Xu, Tim Luckett, Alex Yueping Wang, Melanie Lovell, Jane L Phillips
OBJECTIVE: More than half of all cancer patients experience unrelieved pain. Culture can significantly affect patients' cancer pain-related beliefs and behaviors. Little is known about cultural impact on Chinese cancer patients' pain management. The objective of this review was to describe pain management experiences of cancer patients from Chinese backgrounds and to identify barriers affecting their pain management. METHOD: A systematic review was conducted adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
January 17, 2018: Palliative & Supportive Care
https://www.readbyqxmd.com/read/29338316/retroareolar-masses-and-intraductal-abnormalities-detected-on-screening-ultrasound-can-biopsy-be-avoided
#12
Yang Guo, Madhavi Raghu, Melissa Durand, Regina Hooley
OBJECTIVE: To investigate the malignancy rate of retroareolar masses and intraductal abnormalities discovered in asymptomatic women during screening whole breast ultrasound (US-S) and determine if biopsy can be avoided. METHODS: This is a HIPAA compliant retrospective study. Our radiology electronic medical records were searched for the phrases "retroareolar mass" or "intraductal mass" combined with "screening whole breast ultrasound" performed between 10/1/2009 to 5/30/2015...
January 17, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29338118/impact-of-quality-of-research-on-patient-outcomes-in-the-institute-of-medicine-2013-report-on-dietary-sodium
#13
Aaron Lucko, Chelsea Ta Doktorchik, Norm Rc Campbell
The 2013 Institute of Medicine report entitled "Sodium Intake in Populations: Assessment of Evidence" found inconsistent evidence of health benefit with dietary sodium intake <2300 mg/d. Different studies reported benefit and harm of population dietary intake <2300 mg/d. The Institute of Medicine committee, however, did not assess whether the methodology used in each of the studies was appropriate to examine dietary sodium and health outcomes. This review investigates the association of methodological rigor and outcomes of studies in the Institute of Medicine report...
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29337862/therapeutic-management-of-pseudomonas-aeruginosa-bloodstream-infection-non-susceptible-to-carbapenems-but-susceptible-to-old-cephalosporins-and-or-to-penicillins
#14
Ronit Zaidenstein, Asaf Miller, Ruthy Tal-Jasper, Hadas Ofer-Friedman, Menachem Sklarz, David E Katz, Tsillia Lazarovitch, Paul R Lephart, Bethlehem Mengesha, Oran Tzuman, Mor Dadon, Chen Daniel, Jacob Moran-Gilad, Dror Marchaim
It is unknown as to whether other beta-lactams can be used for bloodstream infections (BSI) resulting from Pseudomonas aeruginosa (PA) which are non-susceptible to one or more carbapenem. We conducted a retrospective cohort study at the Assaf Harofeh Medical Center (AHMC) from January 2010 to August 2014. Adult patients with PA-BSI non-susceptible to a group 2 carbapenem but susceptible to ceftazidime or piperacillin (with or without tazobactam), were enrolled. We compared the outcomes of patients who received an appropriate beta-lactam antibiotic ("cases") to those who received an appropriate non-beta-lactam antibiotic ("controls")...
January 16, 2018: Microorganisms
https://www.readbyqxmd.com/read/29337664/containment-studies-of-transgenic-mosquitoes-in-disease-endemic-countries-the-broad-concept-of-facilities-readiness
#15
M Megan Quinlan, Josephine Birungi, Mamadou B Coulibaly, Abdoulaye Diabaté, Luca Facchinelli, Wolfgang Richard Mukabana, James Mutuku Mutunga, Tony Nolan, Peter Raymond, Sékou F Traoré
Genetic strategies for large scale pest or vector control using modified insects are not yet operational in Africa, and currently rely on import of the modified strains to begin preliminary, contained studies. Early involvement of research teams from participating countries is crucial to evaluate candidate field interventions. Following the recommended phased approach for novel strategies, evaluation should begin with studies in containment facilities. Experiences to prepare facilities and build international teams for research on transgenic mosquitoes revealed some important organizing themes underlying the concept of "facilities readiness," or the point at which studies in containment may proceed, in sub-Saharan African settings...
January 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29337414/proliferative-leukoplakia-proposed-new-clinical-diagnostic-criteria
#16
Alessandro Villa, Reshma S Menon, Alexander R Kerr, Fabio De Abreu Alves, Andres Guollo, David Ojeda, Sook B Woo
OBJECTIVE: We aimed to characterize proliferative verrucous leukoplakia (PVL) from a clinical and histopathologic standpoint and suggest an updated classification. SUBJECTS AND METHODS: Records of patients seen at three oral medicine centers with a clinical diagnosis of PVL were reviewed for clinical and histopathologic features, and malignant transformation (MT). RESULTS: There were 42 patients (median age: 69 years [range:36-88]; 35 females)...
January 16, 2018: Oral Diseases
https://www.readbyqxmd.com/read/29336638/prehospital-administration-of-epinephrine-in-pediatric-anaphylaxis-a-statewide-perspective
#17
Leslie M Cristiano, Brian Hiestand, Jason W Caldwell, W Adam Gower, Antonio R Fernandez, Katherine Gilbert, James E Winslow
OBJECTIVE: Timely administration of epinephrine is critical in the treatment of anaphylaxis. This study sought to determine the frequency of administration of epinephrine by EMS providers caring for pediatric patients in the prehospital setting. METHODS: We examined data from the NC EMS database (PreMIS) from 2010-3 to determine frequency of epinephrine administration in pediatric patients with anaphylaxis. We studied patients <18 years of age with an EMS provider impression of "allergic reaction...
January 16, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29336455/5-vitamin-b12-derivatives-suitable-for-bioconjugation-via-the-amide-bond
#18
A Jackowska, M Chromiński, M Giedyk, D Gryko
Vitamin B12 is an attractive candidate for a drug or an imaging-agent carrier into cells, due to its dietary uptake and well established transport through glycoproteins. Utilization of this system requires an appropriate functionalization of vitamin B12 that both allows for the conjugation of therapeutics and does not interrupt its recognition by transport proteins. Modifications at the 5'-position on the ribose moiety are among a few approaches which meet the criteria. In this article we present vitamin B12 derivatives bearing either the amino or the carboxylic group at the 5'-position...
January 16, 2018: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29336342/-homogeneity-of-the-european-training-program-the-role-of-the-european-board-of-urology
#19
José Luís Domínguez Escrig
From its origins and acting through its specific committees, the E.B.U. has been dedicated to the improvement and standardization of urological training across Europe. Identifying minimal requirements for urology training, publishing a European Curriculum and defining basic rules for accreditation of educational activities, hence, offering a systematic assessment for the recognition of quality. Working through different dedicated committees, the E.B.U. oversees every aspect on the urological training in Europe...
January 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29336285/optimal-cutoff-values-of-allergen-specific-immunoglobulin-e-to-house-dust-mites-and-animal-dander-based-on-skin-prick-test-results-analysis-in-16-209-patients-with-allergic-rhinitis
#20
Sang Duk Hong, Gwanghui Ryu, Min Young Seo, Jong In Jeong, Hyo Yeol Kim, Seung-Kyu Chung, Hun-Jong Dhong
BACKGROUND: The most common tests for allergen sensitization in patients with allergic rhinitis are the skin-prick test (SPT) and an in vitro test to detect serum specific immunoglobulin E (sIgE). However, in vitro allergen test results were interpreted dichotomically as positive or negative at a threshold of 0.35 kU/L of sIgE, regardless of the patient characteristics or antigen types. OBJECTIVE: The purpose of this study was to determine the cutoff value for sIgE in house-dust mites and animal dander, and to analyze differences in cutoff value according to age and gender...
January 25, 2018: American Journal of Rhinology & Allergy
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