Jiahui Wu, Qingcheng Wang, Oushan Tang, Jie Liao, Qiaoling Zhao, Jingjing Liang, Huina Feng, Linhua Wang, Haixing Wang, Qing Shen
Nandrolone (NT) is a type of androgen anabolic steroid that is often illegally used in cattle farming, leading to unpredictable harm to human health via the food chain. In this study, a rapid detection method for NT in the samples of cattle farming was established using a portable mass spectrometer. The instrument parameters were optimized, including a thermal desorption temperature of 220 °C, a pump speed of 30 %, an APCI ionization voltage of 3900 v, and an injection volume of 6 μL. The samples of bovine urine, feed, sewage, and tissue were selected, and extracted using a solution of methanol:acetonitrile (1:1, v/v), followed by spiking a NT standard solution (1000 ng·mL-1 ) and ionization through the APCI ion source for detection...
April 2, 2024: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences