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https://www.readbyqxmd.com/read/29435306/a-strategy-for-the-clinical-remission-of-acute-lymphoblastic-leukemia-elicited-by-treatment-of-%C3%AE-thalassemia-major-a-case-report
#1
Miguel A Palomo-Colli, Marta Zapata-Tarres, Osvaldo D Castelán-Martínez, Luis E Juárez-Villegas, Lourdes P Córdova-Hurtado
Acute lymphoblastic leukemia (ALL) has been suggested as a long-term complication in patients with β-thalassemia major (β-TM). A 12-months-old male patient was diagnosed with β-TM. The patient required a blood transfusion weekly for 2 years. At the age of 4 years, a splenectomy was performed due to massive splenomegaly and frequent transfusion requirements. The histopathological analysis of the spleen revealed extensive hemosiderosis. ALL-L1 with the T immunophenotype and without central nervous system (CNS) involvement was diagnosed when the patient was 5 years old, and treated with anti-leukemic combination chemotherapy and CNS radiotherapy...
February 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29430592/patterns-and-predictors-of-failed-and-sustained-return-to-work-in-transport-injury-insurance-claimants
#2
Shannon E Gray, Behrooz Hassani-Mahmooei, Ian D Cameron, Elizabeth Kendall, Justin Kenardy, Alex Collie
Purpose To determine the incidence of employed people who try and fail to return-to-work (RTW) following a transport crash. To identify predictors of RTW failure. METHODS: A historical cohort study was conducted in the state of Victoria, Australia. People insured through the state-based compulsory third party transport accident compensation scheme were included. Inclusion criteria included date of crash between 2003 and 2012 (inclusive), age 15-70 years at the time of crash, sustained a non-catastrophic injury and received at least 1 day of income replacement...
February 12, 2018: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/29424327/-a-woman-with-spontaneous-neck-pain
#3
M Geerdes, S P Smook, T A von Schükkmann
A 42-year-old woman presented with neck pain without previous trauma. On suspicion of spondylodiscitis, an MRI of the cervical spine was made. This MRI and an additional CT showed calcific tendinitis of the longus colli muscle, a self-limiting disorder.
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29415969/osteoblastic-differentiating-potential-of-dental-pulp-stem-cells-in-vitro-cultured-on-a-chemically-modified-microrough-titanium-surface
#4
Marianna De Colli, Milena Radunovic, Vincenzo L Zizzari, Viviana di Giacomo, Chiara Di Nisio, Adriano Piattelli, José L Calvo Guirado, Barbara Zavan, Amelia Cataldi, Susi Zara
Titanium surface modification is critical for dental implant success. Our aim was to determine surfaces influence on dental pulp stem cells (DPSCs) viability and differentiation. Implants were divided into sandblasted/acid-etched (control) and sandblasted/acid-etched coated with calcium and magnesium ions (CaMg), supplied as composite, (test). Proliferation was evaluated by MTT, differentiation checking osteoblastic gene expression, PGE2 secretion and matrix formation, inflammation by Interleukin 6 (IL-6) detection...
February 8, 2018: Dental Materials Journal
https://www.readbyqxmd.com/read/29398137/prognostic-impact-of-leaflet-to-annulus-index-in-patients-treated-with-transapical-off-pump-echo-guided-mitral-valve-repair-with-neochord-implantation
#5
Andrea Colli, Laura Besola, Matteo Montagner, Danila Azzolina, Nicola Soriani, Erica Manzan, Eleonora Bizzotto, Fabio Zucchetta, Roberto Bellu, Demetrio Pittarello, Gino Gerosa
BACKGROUND: The transapical echo-guided NeoChord repair is a procedure to correct mitral regurgitation (MR) without the need for concomitant annuloplasty for degenerative mitral valve (MV) disease. Lacking strict criteria to define normal annular dimensions for patients undergoing MV repair, we consequently missed having precise selection criteria to identify patients who can benefit from a ringless procedure with respect to who would need a combined annular and leaflet repair. The aim of this study is to identify whether a new preoperative echocardiographic index may predict postoperative outcomes after NeoChord repair...
January 31, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29395366/acute-intraoperative-echocardiographic-changes-after-transapical-off-pump-mitral-valve-repair-with-neochord-implantation
#6
Andrea Colli, Laura Besola, Matteo Montagner, Nicola Soriani, Erica Manzan, Eleonora Bizzotto, Fabio Zucchetta, Danila Azzolina, Roberto Bellu, Cristiano Sarais, Demetrio Pittarello, Gino Gerosa
OBJECTIVES: Our aim is to investigate the acute intraoperative effects of the NeoChord repair procedure on mitral valve (MV) annular geometry and LV function and the impact of these changes on MR at 1-year follow-up. BACKGROUND: Recently transapical off-pump mitral valve repair with NeoChord implantation has been demonstrated to be safe and effective in patients with degenerative mitral regurgitation (DMR). METHODS: We retrospectively analyzed baseline and early postoperative 3-dimensional transesophageal echocardiography of 66 patients who underwent NeoChord repair for isolated posterior leaflet MV disease using semiautomatic off-line analysis software...
January 25, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29388943/corrigendum-reproductive-genetic-carrier-screening-for-cystic-fibrosis-fragile-x-syndrome-and-spinal-muscular-atrophy-in-australia-outcomes-of-12-000-tests
#7
Alison Dalton Archibald, Melanie Jane Smith, Trent Burgess, Katrina Louise Scarff, Justine Elliott, Clare Elizabeth Hunt, Caitlin Barns-Jenkins, Chelsea Holt, Karina Sandoval, Vanessa Siva Kumar, Lisa Ward, Emily Caroline Allen, Sarah Valerie Collis, Shannon Cowie, David Francis, Martin B Delatycki, Eppie Mildred Yiu, R John Massie, Mark Domenic Pertile, Desirée du Sart, Damien Bruno, David J Amor
This corrects the article DOI: 10.1038/gim.2017.134.
February 1, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29375213/neoadjuvant-chemotherapy-for-gastric-cancer-is-it-a-must-or-a-fake
#8
Rossella Reddavid, Silvia Sofia, Paolo Chiaro, Fabio Colli, Renza Trapani, Laura Esposito, Mario Solej, Maurizio Degiuli
AIM: To investigate the neoadjuvant chemotherapy (NAC) effect on the survival of patients with proper stomach cancer submitted to D2 gastrectomy. METHODS: We proceeded to a review of the literature with PubMed, Embase, ASCO and ESMO meeting abstracts as well as computerized use of the Cochrane Library for randomized controlled trials (RCTs) comparing NAC followed by surgery (NAC + S) with surgery alone (SA) for gastric cancer (GC). The primary outcome was the overall survival rate...
January 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29357327/characteristics-of-the-middle-cervical-sympathetic-ganglion-a-systematic-review-and-meta-analysis
#9
Chan Park, Chong Hyun Suh, Ji Eun Shin, Jung Hwan Baek
BACKGROUND: Understanding the characteristics of the middle cervical sympathetic ganglion (MCSG) may minimize procedure-related complications and maximize efficacy during surgery or ultrasound (US)-guided procedures. The location and detection rate of the MCSG were variable in small population studies. Therefore, a large population study or meta-analysis could give more information about the MCSG. OBJECTIVES: We aim to review the published literature and evaluate the anatomical features of the MCSG, including the detection rate, location, size, and a normal variation, and to review the clinical relevance of MCSG for procedures including, US-guided ganglion block, ethanol ablation (EA), or radiofrequency ablation (RFA)...
January 2018: Pain Physician
https://www.readbyqxmd.com/read/29346388/safety-and-pharmacokinetic-profile-of-fixed-dose-ivermectin-with-an-innovative-18mg-tablet-in-healthy-adult-volunteers
#10
Jose Muñoz, Maria Rosa Ballester, Rosa Maria Antonijoan, Ignasi Gich, Montse Rodríguez, Enrico Colli, Silvia Gold, Alejandro J Krolewiecki
ClinicalTrials.gov NCT03173742.
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29342014/patterns-and-predictors-of-return-to-work-after-major-trauma-a-prospective-population-based-registry-study
#11
Alex Collie, Pamela M Simpson, Peter A Cameron, Shanthi Ameratunga, Jennie Ponsford, Ronan A Lyons, Sandra Braaf, Andrew Nunn, James E Harrison, Belinda J Gabbe
OBJECTIVE: To characterize patterns of engagement in work during the 4-year period after major traumatic injury, and to identify factors associated with those patterns. BACKGROUND: Employment is an important marker of functional recovery from injury. There are few population-based studies of long-term employment outcomes, and limited data on the patterns of return to work (RTW) after injury. METHODS: A population-based, prospective cohort study using the Victorian State Trauma Registry...
January 16, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29337886/mechanical-activation-of-adipose-tissue-and-derived-mesenchymal-stem-cells-novel-anti-inflammatory-properties
#12
Stephana Carelli, Mattia Colli, Valeriano Vinci, Fabio Caviggioli, Marco Klinger, Alfredo Gorio
The adipose tissue is a source of inflammatory proteins, such as TNF, IL-6, and CXCL8. Most of their production occurs in macrophages that act as scavengers of dying adipocytes. The application of an orbital mechanical force for 6-10 min at 97 g to the adipose tissue, lipoaspirated and treated according to Coleman procedures, abolishes the expression of TNF-α and stimulates the expression of the anti-inflammatory protein TNF-stimulated gene-6 (TSG-6). This protein had protective and anti-inflammatory effects when applied to animal models of rheumatic diseases...
January 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29332030/what-is-a-more-effective-method-of-cranio-cervical-flexion-exercises
#13
Junhyung Park, Do-Heung Ko, Jingang Her, Jihea Woo
BACKGROUND: Cranio-cervical flexion exercise (CCFE) is a representative exercise that activates the deep muscles of neck pain patients. However, there are a lack of studies that propose specific exercise methods to examine the more effective activity level of the deep cervical flexor. OBJECTIVE: The objective of this study is to propose a more effective exercise method through effect comparison based on an optimal degree of mouth-opening, a mouth-open versus mouth-closed position, eye gaze, and body position change during CCFE...
December 29, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29326344/sternocleidomastoid-tumour-in-neonate-fibromatosis-colli
#14
Joana Cunha Oliveira, Margarida S Abreu, Fernanda Marta Gomes
No abstract text is available yet for this article.
January 10, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29325034/ghrelin-preserves-ischemia-induced-vasodilation-of-male-rat-coronary-vessels-following-beta-adrenergic-receptor-blockade
#15
James T Pearson, Nicola Collie, Regis R Lamberts, Tadakatsu Inagaki, Misa Yoshimoto, Keiji Umetani, Philip Davis, Gerard Wilkins, Pete P Jones, Mikiyasu Shirai, Daryl O Schwenke
Acute myocardial infarction (MI) triggers an adverse increase in cardiac sympathetic nerve activity (SNA). While β-adrenergic receptor (β-AR)-blockers are routinely used for the management of MI, they may also counter β-AR-mediated vasodilation of coronary vessels. We have reported that ghrelin prevents sympathetic activation following MI. Whether ghrelin modulates coronary vascular tone following MI, either through the modulation of SNA, or directly as a vasoactive mediator, has never been addressed.We utilized synchrotron microangiography to image coronary perfusion and vessel internal diameter (ID) in anesthetized Sprague Dawley rats before, and then again 30 mins after induction of an MI (left coronary artery ligation)...
January 9, 2018: Endocrinology
https://www.readbyqxmd.com/read/29310627/continuity-of-care-is-an-important-and-distinct-aspect-of-childbirth-experience-findings-of-a-survey-evaluating-experienced-continuity-of-care-experienced-quality-of-care-and-women-s-perception-of-labor
#16
Hilde Perdok, Corine J Verhoeven, Jeroen van Dillen, Tjerk Jan Schuitmaker, Karla Hoogendoorn, Jolanda Colli, François G Schellevis, Ank de Jonge
BACKGROUND: To compare experienced continuity of care among women who received midwife-led versus obstetrician-led care. Secondly, to compare experienced continuity of care with a. experienced quality of care during labor and b. perception of labor. METHODS: We conducted a questionnaire survey in a region in the Netherlands in 2014 among 790 women after they gave birth. To measure experienced continuity of care, the Nijmegen Continuity Questionnaire was used. Quality of care during labor was measured with the Pregnancy and Childbirth Questionnaire, and to measure perception of labor we used the Childbirth Perception Scale...
January 8, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29305625/ifn-%C3%AE-induces-a-preferential-long-lasting-expression-of-mhc-class-i-in-human-pancreatic-beta-cells
#17
Alexandra Coomans de Brachène, Reinaldo S Dos Santos, Laura Marroqui, Maikel L Colli, Lorella Marselli, Raghavendra G Mirmira, Piero Marchetti, Decio L Eizirik
AIMS/HYPOTHESIS: IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. We tested whether expression of these mediators of beta cell loss is reversible upon IFN-α withdrawal or IFN-α pathway inhibition. METHODS: IFN-α-induced MHC class I overexpression, ER stress and inflammation were evaluated by flow cytometry, immunofluorescence and real-time PCR in human EndoC-βH1 cells or human islets exposed to IFN-α with or without the presence of Janus kinase (JAK) inhibitors...
January 5, 2018: Diabetologia
https://www.readbyqxmd.com/read/29304254/the-relevance-of-proprioception-to-chronic-neck-pain-a-correlational-analysis-of-flexor-muscle-size-and-endurance-clinical-neck-pain-characteristics-and-proprioception
#18
Somayeh Amiri Arimi, Leila Ghamkhar, Amir H Kahlaee
Background: Impairment in the cervical proprioception and deep flexor muscle function and morphology have been regarded to be associated with chronic neck pain (CNP). Objective:  The aim of the study is to assess the relationship between proprioception and flexor endurance capacity and size and clinical CNP characteristics. Design:  This was an observational, cross-sectional study. Setting:  Rehabilitation hospital laboratory...
January 2, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29301515/effectiveness-of-employer-financial-incentives-in-reducing-time-to-report-worker-injury-an-interrupted-time-series-study-of-two-australian-workers-compensation-jurisdictions
#19
Tyler J Lane, Shannon Gray, Behrooz Hassani-Mahmooei, Alex Collie
BACKGROUND: Early intervention following occupational injury can improve health outcomes and reduce the duration and cost of workers' compensation claims. Financial early reporting incentives (ERIs) for employers may shorten the time between injury and access to compensation benefits and services. We examined ERI effect on time spent in the claim lodgement process in two Australian states: South Australia (SA), which introduced them in January 2009, and Tasmania (TAS), which introduced them in July 2010...
January 5, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29289624/laparoscopic-approach-for-shull-repair-of-pelvic-floor-defects
#20
Stefano Restaino, Carlo Ronsini, Angelo Finelli, Alessandro Santarelli, Giovanni Scambia, Francesco Fanfani
Study Objective To prove the feasibility of Shull technique by a laparoscopy approach in patient affected by pelvic organ prolapse (POP) with apical loss of support. Design A step-by-step demonstration of the technique in a surgical video, including the fundamental steps for a laparoscopic uterosacral ligament suspension (USLS) (Canadian Task Force Classification III). Setting According to the National Health and Nutrition Examination Survey, approximately 3% of women in the United States report symptoms linked to POP...
December 28, 2017: Journal of Minimally Invasive Gynecology
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