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https://www.readbyqxmd.com/read/28822472/tens-like-stimulation-downregulates-inflammatory-cytokines-in-a-pc-12-cell-line
#1
Guy Sovak, Brian Budgell
OBJECTIVES: The purpose of this study was to evaluate the effects of transcutaneous electrical nerve stimulation (TENS)-like stimulation on the expression of the proinflammatory cytokines tumor necrosis factor α (TNF-α), interleukin 1β (IL-1β), and IL-6 in PC-12 cells, which are commonly used as neuronal cell models. METHODS: Nerve growth factor-differentiated PC-12 cells were exposed to electrical stimulation for 15 minutes at 1 mA, 200 μs, and 100 Hz. Cell lysate from stimulated and control cells was assayed for TNF-α, IL-1β, and IL-6...
July 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28821966/application-of-transcutaneous-ultrasonography-for-the-diagnosis-of-muscle-mass-loss-in-patients-with-liver-cirrhosis
#2
Kazufumi Kobayashi, Hitoshi Maruyama, Soichiro Kiyono, Sadahisa Ogasawara, Eiichiro Suzuki, Yoshihiko Ooka, Tetsuhiro Chiba, Naoya Kato, Tadashi Yamaguchi
BACKGROUND: To propose an ultrasound-based parameter for the diagnosis of muscle mass loss (MML) in cirrhosis. METHODS: This is an IRB-approved cross-sectional study (October 2013 to January 2017) with written informed consent including 357 subjects-234 cirrhosis and 123 controls. MML was diagnosed using the skeletal muscle index at the L3 level (L3-SMI) on computed tomography (CT). Transcutaneous ultrasound was used to demonstrate a cross section of the right iliopsoas muscle, and the iliopsoas muscle index (IP index) was defined by the iliopsoas muscle area/height(2) (mm(2)/m(2))...
August 18, 2017: Journal of Gastroenterology
https://www.readbyqxmd.com/read/28817978/transcutaneous-electrical-nerve-stimulation-tens-as-an-adjunct-for-pain-management-in-perioperative-settings-a-critical-review
#3
Mark I Johnson
Surgical procedures are ever more complex. Day-case surgical loads are increasing and the length of hospital stays are reducing. Management of pain in perioperative settings remains a challenge. Expert panels recommend a multimodal approach which is often interpreted by medical practitioners as polypharmacy. There is variability in non-pharmacological interventions offered to patients, although transcutaneous electrical nerve stimulation (TENS) has been used since the 1970s. Recommendations from expert panels are inconsistent about the use of TENS in perioperative pain settings...
August 18, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28813933/robotic-learning-from-demonstration-of-therapist-s-time-varying-assistance-to-a-patient-in-trajectory-following-tasks
#4
Mohammad Najafi, Kim Adams, Mahdi Tavakoli
The number of people with physical disabilities and impaired motion control is increasing. Consequently, there is a growing demand for intelligent assistive robotic systems to cooperate with people with disability and help them carry out different tasks. To this end, our group has pioneered the use of robot learning from demonstration (RLfD) techniques, which eliminate the need for task-specific robot programming, in robotic rehabilitation and assistive technologies settings. First, in the demonstration phase, the therapist (or in general, a helper) provides an intervention (typically assistance) and cooperatively performs a task with a patient several times...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28809681/a-prototype-therapy-system-for-transcutaneous-application-of-boiling-histotripsy
#5
Adam D Maxwell, Petr V Yuldashev, Wayne Kreider, Tatiana D Khokhlova, George R Schade, Timothy L Hall, Oleg A Sapozhnikov, Michael R Bailey, Vera A Khokhlova
Boiling histotripsy is a method of focused ultrasound surgery that noninvasively applies millisecond-length pulses with high-amplitude shock fronts to generate liquefied lesions in tissue. Such a technique requires unique outputs compared to a focused ultrasound thermal therapy apparatus, particularly to achieve high in situ pressure levels through intervening tissue. This article describes the design and characterization of a system capable of producing the necessary pressure to transcutaneously administer boiling histotripsy therapy through clinically relevant overlying tissue paths using pulses with duration up to 10 ms...
August 14, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28806309/single-center-experience-of-over-a-hundred-implantations-of-a-transcutaneous-bone-conduction-device
#6
Panagiotis A Dimitriadis, Daniel Hind, Kay Wright, Vicki Proctor, Larissa Greenwood, Suzanne Carrick, Jaydip Ray
OBJECTIVE: To assess outcomes with a novel passive transcutaneous bone conduction device (t-BCD). STUDY DESIGN: Prospective data collection and patient review. SETTING: Tertiary referral center. PATIENTS: Patients who underwent implantation with the t-BCD between November 2013 and September 2016. INTERVENTION: Implantation of BAHA Attract. MAIN OUTCOME MEASURES: Surgical outcome, patient reported outcomes including the "Glasgow Benefit Inventory" and the "Client Oriented Scale of Improvement" for adults and the "Speech, Spatial and Qualities of Hearing scale" (SSQ-12) for children...
August 10, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28805960/factors-associated-with-high-pain-intensity-during-wound-care-procedures-a-model
#7
Sue E Gardner, Linda I Abbott, Catherine A Fiala, Barbara A Rakel
The most common wound care procedures (WPCs) performed on open wounds are dressing changes and wound cleansing. Dressing changes cause moderate to severe pain in 74% of patients, nearly half (36%) of whom experience severe pain (rated as 8-10 on a 10-point numeric rating scale). The purpose of this paper is to propose a model of clinically accessible factors that can be tested in order to develop a clinical tool to identify which patients are likely to experience high intensity pain during nonoperative WCPs, such as dressing changes...
June 8, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28804223/the-effect-of-transcutaneous-electrical-acupoint-stimulation-on-inflammatory-response-in-patients-undergoing-limb-ischemia-reperfusion
#8
Yunchang Mo, Sijia Chen, Lili Yang, Ledan Huang, Dan Jin, Zhi Yu, Leilei Wang, Liangrong Wang, Shan Luo, Junlu Wang
Reperfusion after tourniquet use can induce inflammation and cause remote organ injury. We evaluated the therapeutic effect of transcutaneous electrical acupoint stimulation (TEAS) on inflammatory mediators and lung function in patients receiving lower limb tourniquets. Forty patients undergoing unilateral lower extremity surgery with tourniquet were randomly assigned to two groups: the TEAS group and ischemia-reperfusion (I/R) group. The C-C motif chemokine ligand 2 (CCL2), C-X-C motif chemokine ligand 8 (CXCL8), interleukin-1 (IL-1), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor-α (TNF-α), and arterial blood gas analysis were measured preoperatively and 6 h after tourniquet removal...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28803834/transcutaneous-auricular-vagal-nerve-stimulation-tavns-might-be-a-mechanism-behind-the-analgesic-effects-of-auricular-acupuncture
#9
Taras Usichenko, Henriette Hacker, Martin Lotze
BACKGROUND: Randomized clinical trials (RCT) demonstrated that auricular acupuncture (AA) is effective in treatment of acute and chronic pain, although the mechanisms behind AA are not elucidated. METHODS: The data concerning the localization of AA points, which are commonly used to treat pain, were extracted from the meta-analysis of 17 RCTs and evaluated using the anatomical map of auricular afferent nerve supply. RESULTS: Fifteen out of 20 specific AA points, used in the treatment of pain, are situated in areas innervated mostly by the auricular branch of the vagal nerve (ABVN), whereas sham stimulation was applied at the helix of the auricle, innervated by cervical nerves...
August 2, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28802098/response-time-of-indirectly-accessed-gas-exchange-depends-on-measurement-method
#10
Jakub Rafl, Filip Kulhanek, Petr Kudrna, Vaclav Ort, Karel Roubik
Noninvasive techniques are routinely used for assessment of tissue effects of lung ventilation. However, comprehensive studies of the response time of the methods are scarce. The aim of this study was to compare the response time of noninvasive methods for monitoring of gas exchange to sudden changes in the composition of the inspired gas. A prospective experimental study with 16 healthy volunteers was conducted. A ventilation circuit was designed that enabled a fast change in the composition of the inspiratory gas mixture while allowing spontaneous breathing...
August 12, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28797281/the-efficacy-of-transcutaneous-electrical-nerve-stimulation-on-the-improvement-of-walking-distance-in-patients-with-peripheral-arterial-disease-with-intermittent-claudication-study-protocol-for-a-randomised-controlled-trial-the-tens-pad-study
#11
Florent Besnier, Jean-Michel Sénard, Vincent Grémeaux, Mélanie Riédel, Damien Garrigues, Thibaut Guiraud, Marc Labrunée
BACKGROUND: In patients with peripheral arterial disease (PAD), walking improvements are often limited by early pain onset due to vascular claudication. It would thus appear interesting to develop noninvasive therapeutic strategies, such as transcutaneous electrical nerve stimulation (TENS), to improve the participation of PAD patients in rehabilitation programmes, and thus improve their quality of life. Our team recently tested the efficacy of a single 45-min session of 10-Hz TENS prior to walking...
August 10, 2017: Trials
https://www.readbyqxmd.com/read/28794965/efficacy-of-lung-volume-optimization-maneuver-monitored-by-optoelectronic-pletismography-in-the-management-of-congenital-diaphragmatic-hernia
#12
G Lista, I Bresesti, F Cavigioli, F Castoldi, E Lupo, A LoMauro, A Aliverti
Newborns affected by congenital diaphragmatic hernia (CDH) need cardio-respiratory stabilization before undergoing surgical repair. Open lung strategy is a well-established approach to optimize lung volume in preterm infants with Respiratory Distress Syndrome (RDS), using both High Frequency Oscillatory Ventilation (HFOV) and Conventional Mechanical Ventilation (CMV). We report a case of left CDH with severe lung hypoplasia, managed applying open lung strategy in HFOV (pre-surgery period) and in Assist-Control with Volume Guarantee (post-surgery period), guided by SpO2 changes, TcPO2 and TcPCO2 monitoring...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28792105/transcutaneous-posterior-tibial-nerve-electrostimulation-with-low-dose-trospium-chloride-could-it-be-used-as-a-second-line-treatment-of-overactive-bladder-in-females
#13
Amr Abulseoud, Ahmed Moussa, Gaber Abdelfattah, Ibrahim Ibrahim, Emmanuel Saba, Mohamed Hassouna
AIM: To evaluate the effect of adding low dose trospium chloride with transcutaneous posterior tibial nerve stimulation (TPTNS) in the treatment of overactive bladder (OAB) in females after failure of behavioral therapy. METHODS: We randomized 30 women with OAB, in two groups: G I received 30 min TPTNS, three times a week; GII received TPTNS plus 20 mg trospium chloride daily. OAB Symptom Score questionnaire (OABSS), Incontinence Impact Questionnaire-short form 7 (IIQ-7), 3 day voiding diary and urodynamics at weeks 0 and 8 were evaluated...
August 9, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28783627/post-hoc-analysis-of-passive-cavitation-imaging-for-classification-of-histotripsy-induced-liquefaction-in-vitro
#14
Kenneth B Bader, Kevin J Haworth, Adam D Maxwell, Christy K Holland
Histotripsy utilizes focused ultrasound to generate bubble clouds for transcutaneous tissue liquefaction. Image guidance of histotripsy pulses is required to provide spatially resolved monitoring of treatment progress. The aim of this study was to investigate the feasibility of plane wave B-mode and passive cavitation images to be used as binary classifiers of histotripsy-induced liquefaction. Prostate tissue phantoms were exposed to mechanically ablative histotripsy pulses over a range of pulse durations (5 - 20 μs) and peak negative pressures (12 - 23 MPa)...
August 2, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28779926/the-effect-of-transcutaneous-electrical-nerve-stimulation-on-the-severity-of-labor-pain-among-nulliparous-women-a-clinical-trial
#15
Roonak Shahoei, Shole Shahghebi, Masomeh Rezaei, Shayan Naqshbandi
INTRODUCTION: This study aimed to investigate the effect of transcutaneous electrical nerve stimulation on labor pain among nulliparous women referred to a hospital in an urban area of Iran. MATERIALS AND METHODS: Samples were consisted of 90 nulliparous women. They were randomly assigned into three groups with equal number in each groups: experiment group, placebo group and control. Pain was measured using the visual pain severity scale. FINDINGS: The mean of the severity of labor pain indicated a statistically significant difference after the intervention...
August 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28777054/an-investigation-of-skin-perfusion-in-venous-leg-ulcer-after-exercise
#16
Omar Mutlak, Mohammed Aslam, Nigel J Standfield
INTRODUCTION: A venous leg ulcer (VLU) has a major impact on the quality of life and functional ability of individuals, but no single treatment is yet effective. This study investigates the changes induced by dorsiflexion exercise on skin perfusion in VLU patients to achieve a better understanding of venous ulcer pathophysiology. METHODS: Seventy-eight venous leg ulcer patients were randomised into four groups. The non-exercise groups included a control group (n = 18) and a compression therapy group (n = 20) and the exercise groups included an exercise-only group (n = 20) and a compression and exercise group (n = 20)...
July 1, 2017: Perfusion
https://www.readbyqxmd.com/read/28776593/relationship-between-the-phenylephrine-test-and-eyelid-droop-after-aponeurotic-repair-with-the-use-of-an-epinephrine-containing-local-anaesthetic
#17
H Matsuda, T Shiba, Y Takahashi, H Tsuneoka
PurposeTo analyse the relationship between the results of the phenylephrine test and postoperative eyelid droop in transcutaneous aponeurotic repair using epinephrine-containing local anaesthetic for aponeurotic blepharoptosis.Patients and methodsWe retrospectively reviewed the medical records of 66 eyelids from 40 patients who underwent transcutaneous aponeurotic repair. A positive phenylephrine test result was defined as an increase in margin reflex distance-1 (MRD-1) ≥0.5 mm after application of phenylephrine eye drops...
August 4, 2017: Eye
https://www.readbyqxmd.com/read/28774696/neglected-endemic-mycoses
#18
REVIEW
Flavio Queiroz-Telles, Ahmed Hassan Fahal, Diego R Falci, Diego H Caceres, Tom Chiller, Alessandro C Pasqualotto
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous implantation is also an important source of infections. Environmental exposure to spores of pathogenic fungi can result in subclinical and unrecognised syndromes, allergic manifestations, and even overt disease. After traumatic cutaneous inoculation, several fungi can cause neglected mycoses such as sporotrichosis, chromoblastomycosis, mycetoma, entomophthoramycosis, and lacaziosis. Most of these diseases have a subacute to chronic course and they can become recalcitrant to therapy and lead to physical disabilities, including inability to work, physical deformities, and amputations...
July 31, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28771172/development-of-novel-faster-dissolving-microneedle-patches-for-transcutaneous-vaccine-delivery
#19
Akihiko Ono, Sayami Ito, Shun Sakagami, Hideo Asada, Mio Saito, Ying-Shu Quan, Fumio Kamiyama, Sachiko Hirobe, Naoki Okada
Microneedle (MN) patches are promising for transcutaneous vaccination because they enable vaccine antigens to physically penetrate the stratum corneum via low-invasive skin puncturing, and to be effectively delivered to antigen-presenting cells in the skin. In second-generation MN patches, the dissolving MNs release the loaded vaccine antigen into the skin. To shorten skin application time for clinical practice, this study aims to develop novel faster-dissolving MNs. We designed two types of MNs made from a single thickening agent, carboxymethylcellulose (CMC) or hyaluronan (HN)...
August 3, 2017: Pharmaceutics
https://www.readbyqxmd.com/read/28767271/effects-of-transcutaneous-electrical-acupoint-stimulation-on-motor-functions-and-self-care-ability-in-children-with-cerebral-palsy
#20
Bei Zhang, Yulan Zhu, Congyu Jiang, Ce Li, Yingying Li, Yulong Bai, Yi Wu
OBJECTIVES: To observe the effects of transcutaneous electrical acupoint stimulation (TEAS) in improving motor functions and self-care abilities in children with cerebral palsy in their early childhood. DESIGN: A preliminary, prospective, cohort study. SETTINGS/LOCATION: Multicenter. SUBJECTS: Children aged 2-6 years old. INTERVENTIONS: Twenty-three children were included in the study and randomly assigned to a control group ([CG] N = 11) or a therapeutic group ([TG] N = 12)...
August 2, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
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