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https://www.readbyqxmd.com/read/29165640/toxicokinetics-of-deltamethrin-dosage-dependency-vehicle-effects-and-low-dose-age-equivalent-dosimetry-in-rats
#1
Tanzir Mortuza, Chen Chen, Catherine A White, Brian S Cummings, S Muralidhara, Darren Gullick, James V Bruckner
There is increasing concern that infants and children may be at increased risk of neurological effects of pyrethroids, the most widely used class of insecticide. The objectives of this investigation were to: (1) characterize the dose-dependent toxicokinetics (TK) of deltamethrin (DLM) for exposures ranging from environmentally-relevant to acutely toxic; (2) determine the influence of an aqueous versus oil vehicle on oral absorption and bioavailability; and (3) determine whether DLM exhibits low-dose, age-equivalent internal dosimetry...
November 20, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29164632/characterization-of-nanodot-optically-stimulated-luminescence-detectors-and-high-sensitivity-mcp-n-thermoluminescent-detectors-in-the-40-300-kvp-energy-range
#2
Yannick Poirier, Svetlana Kuznetsova, Jose Eduardo Villarreal-Barajas
PURPOSE: To investigate empirically the energy dependence of the detector response of two in-vivo luminescence detectors, LiF:Mg,Cu,P (MCP-N) high-sensitivity TLDs and Al2 O3 :C OSLDs, in the 40-300-kVp energy range in the context of in-vivo surface dose measurement. As these detectors become more prevalent in clinical and pre-clinical in-vivo measurements, knowledge of the variation of the empirical dependence of the measured response of these detectors across a wide spectrum of beam qualities is important...
November 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/29164618/analysis-of-erythemal-uvb-dose-received-inside-a-car-in-valencia-spain
#3
Gonzalo Gurrea Ysasi, Vicente Blanca Giménez, Juan Carlos Moreno, MªAntonia Serrano
Continuous exposures to ultraviolet radiation can lead to harmful effects on human skin. Professional drivers may spend more than 8 hours per day inside a vehicle. This paper describes an analysis of the UVER (erythemal ultraviolet radiation) received by a driver and passenger inside a vehicle. A 3-door Peugeot 206 was used for the study. VioSpor Blue Line dosimeters (with a response profile close to that of human skin) were used to measure the erythematic dose of UV radiation (able to produce erythema on human skin)...
November 22, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29164365/organ-doses-and-lifetime-attributable-risk-evaluations-for-scoliosis-examinations-of-adolescent-patients-with-the-eos-imaging-system
#4
Marco Branchini, Antonella Del Vecchio, Carmen Rosaria Gigliotti, Alessandro Loria, Alberto Zerbi, Riccardo Calandrino
PURPOSE: The goal of this work is to evaluate organ doses and lifetime attributable risk of cancer incidence and mortality in scoliosis examinations of adolescent patients performed with EOS imaging system, in order to optimize patient dose and protocols. METHODS: An anthropomorphic phantom of a normal patient, with thermoluminescent dosimeters in correspondence with the main organs at risk, was imaged with both EOS and computed radiography (CR). For each modality, effective dose was calculated from the measured organ doses...
November 21, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/29161779/micronuclei-assay-in-exfoliated-buccal-cells-of-radiation-treated-oral-cancer-patients
#5
Gayathri Ramesh, Smriti Chaubey, Amrita Raj, Ravi Kumar Seth, Anuradha Katiyar, Amit Kumar
BACKGROUND: Micronuclei are suitable internal dosimeters for revealing tissue-specific genotoxic damage in individuals exposed to carcinogenic mixtures. Evaluation of radiation-induced cellular changes to predict radiosensitivity has invested many investigators since such changes were first found in biopsy material. AIM: The aim of the present study was to assess the relationship of with histopathological grade and number of radiation therapy sittings with the frequency of micronuclei and nuclear anomalies among oral cancer patients...
November 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/29160405/dosimetry-in-cbct-with-different-protocols-emphasis-on-small-fovs-including-exams-for-tmj
#6
Helena Aguiar Ribeiro Nascimento, Marcos Ely Almeida Andrade, Marco Antonio Gomes Frazão, Eduarda Helena Leandro Nascimento, Flavia Maria Moraes Ramos-Perez, Deborah Queiroz Freitas
This study aimed to estimate the absorbed dose in cone beam computed tomography (CBCT) exams according to different exposure parameters and size and position of the field of view (FOV). In addition was compared the absorbed dose of two smaller FOV scans with that of a larger FOV scan for evaluation of temporomandibular joint (TMJ), as it is a bilateral structure. CBCT scans were obtained on OP300 Maxio unit varying scanning mode (standard, high and endo) as well as size (5x5, 6x8 and 8x15 cm) and positioning of FOV...
July 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/29159807/experimental-investigation-of-gafchromic-%C3%A2-ebt3-intrinsic-energy-dependence-with-kilovoltage-x-rays-137-cs-and-60-co
#7
Cliff G Hammer, Benjamin Saul Rosen, Jessica M Fagerstrom, Wesley S Culberson, Larry A DeWerd
PURPOSE: To determine experimentally the intrinsic energy response, kbq , of EBT3 GafChromic(®) radiochromic film with kilovoltage x-rays,(137) Cs, and (60) Co in therapeutic and diagnostic dose ranges through direct measurement with an accompanying mathematical approach to describe the physical processes involved. METHODS: EBT3 film was irradiated to known doses using (60) Co, (137) Cs, and 13 NIST-matched kilovoltage x-ray beams. Seven dose levels, ranging from 57 to 7002 mGy, were chosen for this work...
November 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/29155416/eye-lens-dose-monitoring-in-the-uk-nuclear-industry-using-active-personal-dosemeters
#8
Andrew Forrest McWhan, Wioletta Dobrzynska
The reduction of the dose limit for eye lens from 150 to 20 mSv year-1 must be implemented by EU member states by February 2018. Consequently, there is a requirement for all employers engaged with work with ionising radiation to have appropriate monitoring arrangements in place by this date to demonstrate that they can meet this new limit for all workers. Eye lens dose is conventionally monitored by specific dosemeters worn near the eye. However, it is usually impractical for these dosemeters to be worn at all times in the workplace which can lead to problems accounting for any periods of work when an eye lens dosemeter has not been worn...
November 20, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29151472/-fricke-gel-dosimeters
#9
Takuya Maeyama
Fricke gel dosimeters are based on the aqueous ferrous sulfate solution that has been used as a reliable chemical dosimeter for more than 90 years. The amount of radiation-induced oxidation of ferrous ions to ferric ions could be evaluated three-dimensionally via optical computed tomography (OCT) or magnetic resonance imaging (MRI). Three-dimensional dosimetry is expected to be a useful tool, in particular, for the verification of complex radiation dose planning in advanced radiation cancer therapy. Compared with other 3D gel dosimeters, there are several problems such as retention of dose distribution or dose sensitivity; however, they can easily be prepared in a chemistry laboratory...
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/29151471/-radiochromic-hydrogel-dosimeters
#10
Shuji Usui
Radiochromic hydrogel dosimeters are a useful tool for the verification of 3D dose distributions using optical CT scanners which are lower cost and with higher spatial resolution in a limited time than MRI scanners. In this paper, recent development of radiochromic micelle gel and genipin-gelatin gel dosimeters are described. They have the advantage of water equivalency, low or no diffusion property, and lower toxicity. Micelle gels consist of leuco dye, surfactant, radical initiator (halocarbons), and gelling agent...
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/29151470/-polymer-gel-dosimeter
#11
Shin-Ichiro Hayashi
With rapid advances being made in radiotherapy treatment, three-dimensional (3D) dose measurement techniques of great precision are required more than ever before. It is expected that 3D polymer gel dosimeters will satisfy clinical needs for an effective detector that can measure the complex 3D dose distributions. Polymer gel dosimeters are devices that utilize the radiation-induced polymerization reactions of vinyl monomers in a gel to store information about radiation dose. The 3D absorbed dose distribution can be deduced from the resulting polymer distribution using several imaging modalities, such as MRI, X-ray and optical CTs...
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/29151469/-introduction-of-this-special-issue-on-3d-gel-dosimeters
#12
Satoshi Obara, Akihiro Nohtomi
No abstract text is available yet for this article.
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/29151467/-preface-to-the-special-issue-on-3d-gel-dosimeters
#13
Masahiro Endo
No abstract text is available yet for this article.
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/29151462/-evaluation-of-radiochromic-gel-dosimeter-and-optical-ct
#14
Munehiro Yonehara, Ryo Wakana, Kazuhisa Sakakibara, Jun'ichi Kotoku, Takanori Kobayashi, Hiroaki Gotoh
Three-dimensional (3D) radiation dosimeter has received growing interest with the implementation of highly conformal radiotherapy treatments. Optical Computed tomography (CT) scanners have been developed for 3D quantitative measurement of optical attenuation. Malachite green and Leuco Crystal Violet (LCV) dye radiochromic gels were recently developed as radiation dosimeters in combination with optical CT scanners. Malachite green and LCV are colorless dyes and they become green or violet after irradiation, respectively...
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/29151461/-optical-computed-tomography-for-polymer-gel-dosimetry
#15
Hiraku Kawamura, Takaoki Takanashi, Yoshikazu Shimada, Yuichi Sato, Shinji Abe, Satoshi Hara
This article describes an optical computed tomography (OCT) for polymer gel dosimetry, focusing on two systems recently constructed by us. The first OCT system, which is categorized as a first-generation system, comprised a single He-Ne laser, photodiode, and mechanical stages for moving and turning gel dosimeter. Projection data per angle are acquired from turned gel dosimeter. In this system, the reconstructed image is obtained using filtered back-projection (FBP) method from projection data. The second OCT system is a 2D-OCT scanner that utilizes a light panel and a camera detector...
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/29151460/-evaluation-of-absorbed-dose-by-mri-read-out
#16
Shuji Usui
Three dimensional dose distribution by gel dosimeters is often read out by an MRI scanner, which is readily available in most hospitals. Both the T1 and T2 relaxation rates are used to evaluate the absorbed dose. This paper will describe the principle of the imaging sequences (spin echo, multiple spin echo, and inversion recovery methods) to measure the relaxation rate and the factors to affect the precision (signal noise ratio, temperature during scanning, coil, imaging artefact). Additionally, the magnetization transfer method will be mentioned as an alternative for low-density foam gel dosimeters...
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/29149420/blood-clearance-and-occupational-exposure-for-177-lu-dotatate-compared-to-177-lu-psma-radionuclide-therapy
#17
Mohammad Abuqbeitah, Mustafa Demir, Lebriz Uslu-Beşli, Nami Yeyin, Kerim Sönmezoğlu
The main target of this work is to examine blood clearance and external exposure for (177)Lu-DOTATATE compared with new emerging (177)Lu-PSMA therapy. Blood clearance and radiation exposure of 31 patients treated with 5.5 ± 1.1 GBq (177)Lu-DOTATATE were compared to those of 23 patients treated with 7.4 GBq (177)Lu-PSMA. Dose rates were measured at several distances and time points up to 120 h after treatment. Blood samples were collected conjunctively after infusion. Caregiver's cumulative dose was measured by means of an OSL (optically stimulated luminescence) dosimeter for 4-5 days and medical staff's dose was also estimated using electronic personal dosimeters...
November 17, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/29140797/characterising-endourologist-learning-curve-during-percutaneous-nephrolithotomy-implications-on-occupational-dose-and-patients
#18
Jacobo Guiu-Souto, Carlos Otero, Daniel A Pérez-Fentes, Carlos Fernández-Baltar, Juan Francisco Sánchez-Garcia, Camilo García-Freire, Miguel Pombar-Cameán, Juan Pardo-Montero
In this study we have characterised the learning curve for percutaneous nephrolithotomy procedures over 301 cases for six years. Different surrogate parameters of clinical expertise have been used, such as dose area product, total procedure time, fluoroscopy time and personal equivalent doses. In addition, two different endourologists have been monitored; one of whom had specific Radiation Protection training (ICRP 85). Eye lens dose was estimated from thermoluminescent dosimeters. Significant differences were observed between both endourologists, especially in the fluoroscopy time...
November 15, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29140458/direct-measurements-of-skin-eye-lens-and-thyroid-dose-during-pediatric-brain-ct-examinations
#19
Agapi Ploussi, Ioannis Stathopoulos, Vasileios Syrgiamiotis, Triantafillia Makri, Christiana Hatzigiorgi, Kalliopi Platoni, Eleftheria Carinou, Efstathios P Efstathopoulos
Pediatric brain computed tomography (CT) is identified as the most frequent CT examination in children. The aim of the study is the direct measurement of skin, eye lens and thyroid dose in pediatric patients during brain CT examinations. The study included 35 pediatric patients who underwent brain CT examinations. The patients were categorized in three age groups: Group A (age range: 0.8-1 years), Group B (age range: 2.0-4.9 years) and Group C (age range: 5.5-15.5 years). thermoluminescent dosimeters (TLDs) were placed on the eyes, the frontal region of the head, the mastoid apophysis and the thyroid gland...
November 13, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29136230/high-dose-tl-dosimetry-of-reactor-neutrons
#20
Barbara Obryk, Klaudia Malik, Pawel Bilski, Andrzej Igielski, Jan Dankowski, Arkadiusz Kurowski, Rafal Prokopowicz, Krzysztof Pytel
Radiation dose was measured with set of TL dosimeters during checkout of neutron radiation hardness of the ORTEC preamplifier type 142A in the experiment at the MARIA nuclear reactor at the National Centre for Nuclear Research (NCBJ), Otwock-Świerk, Poland. Different types of LiF-based TL detectors have been used for measurements in order to evaluate neutron and non-neutron components of the radiation field in the reactor channel during exposure and to check their relevancy for dose measurements in the reactor environment...
November 10, 2017: Radiation Protection Dosimetry
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