Jack F Cazet, Stefan Siebert, Hannah Morris Little, Philip Bertemes, Abby S Primack, Peter Ladurner, Matthias Achrainer, Mark T Fredriksen, R Travis Moreland, Sumeeta Singh, Suiyuan Zhang, Tyra G Wolfsberg, Christine E Schnitzler, Andreas D Baxevanis, Oleg Simakov, Bert Hobmayer, Celina E Juliano
The epithelial and interstitial stem cells of the freshwater polyp Hydra are the best characterized stem cell systems in any cnidarian, providing valuable insight into cell type evolution and the origin of stemness in animals. However, little is known about the transcriptional regulatory mechanisms that determine how these stem cells are maintained and how they give rise to their diverse differentiated progeny. To address such questions, a thorough understanding of transcriptional regulation in Hydra is needed...
January 13, 2023: Genome Research