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tropical pancreatitis

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https://www.readbyqxmd.com/read/27912864/clinical-and-epidemiological-aspects-of-scorpionism-in-the-world-a-systematic-review
#1
REVIEW
Maria S V Santos, Cláudio G L Silva, Basílio Silva Neto, Cícero R P Grangeiro Júnior, Victor H G Lopes, Antônio G Teixeira Júnior, Deryk A Bezerra, João V C P Luna, Josué B Cordeiro, Jucier Gonçalves Júnior, Marcos A P Lima
OBJECTIVE: Scorpion stings are registered worldwide, but the incidence and the features of the envenomations vary depending on the region. The aim of this review was to summarize the epidemiological, clinical, diagnostic, and therapeutic data worldwide regarding humans stung by scorpions. METHODS: A systematic review of the literature was conducted through the online databases of the Virtual Health Library (VHL), which hosts Medline and the Latin American and Caribbean Center on Health Sciences Informational (LILACS) database...
December 2016: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/27783351/progression-of-recurrent-acute-and-chronic-pancreatitis-a-short-term-follow-up-study-from-a-southern-indian-centre
#2
M Ganesh Kamath, C Ganesh Pai, Asha Kamath
BACKGROUND: Little data exist on the progression of recurrent acute (RAP) and chronic pancreatitis (CP) from regions from where the entity of tropical chronic pancreatitis was originally described. The study aimed to follow up patients with RAP and CP seen at a southern Indian centre for progression of disease over time. METHODS: Prospectively enrolled patients with RAP and CP were followed up, and the alcoholic and idiopathic subgroups were assessed for progression of structural and functional changes in the organ...
October 26, 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/27659534/tumor-specific-gene-therapy-for-pancreatic-cancer-using-human-neural-stem-cells-encoding-carboxylesterase
#3
Sung S Choi, Kichul Yoon, Seon-A Choi, Seung-Bin Yoon, Seung U Kim, Hong J Lee
Advanced pancreatic cancer is one of the most lethal malignant human diseases lacking effective treatment. Its extremely low survival rate necessitates development of novel therapeutic approach. Human neural stem cells (NSCs) are known to have tumor-tropic effect. We genetically engineered them to express rabbit carboxyl esterase (F3.CE), which activates prodrug CPT-11(irinotecan) into potent metabolite SN-38. We found significant inhibition of the growth of BxPC3 human pancreatic cancer cell line in vitro by F3...
September 21, 2016: Oncotarget
https://www.readbyqxmd.com/read/27608778/mortality-predictors-of-ards-in-medical-intensive-care-unit-of-a-tertiary-care-centre-in-a-tropical-country
#4
Rakesh Bhadade, Rosemarie de'Souza, Minal Harde, Dileep Asgaonkar, Nilesh Tuplondhe
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a clinical syndrome of severe dyspnoea of rapid onset, hypoxemia, and diffuse pulmonary infiltrates leading to respiratory failure in the absence of cardiac failure. We did the study to asses various aetiologies of ARDS, to determine the correlation between the diagnostic criteria, mortality predictors, need of mechanical ventilation and the outcome of patients. This was an observational, prospective study in medical intensive care unit (MICU) of a tertiary care hospital, over a period of 15 months...
November 2015: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27608777/predicting-survival-in-ards
#5
EDITORIAL
Niteen D Karnik, Anish V Gupta
Acute respiratory distress syndrome (ARDS) is a fulminant clinical disorder of varied etiology, characterized by diffuse lung injury and severe hypoxemia. It is a leading cause of ICU admission and the associated high mortality has sparked a lot of research on etiology, outcome, scoring systems, mortality predictors, biomarkers including inflammatory cytokines and even genomics in ARDS. The previously used AECC (American European Consensus Conference) definition (1994) of ARDS was replaced by the recent Berlin definition (2012) so as to improve its validity and reliability...
November 2015: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27406389/a-fatal-yellow-fever-virus-infection-in-china-description-and-lessons
#6
Zhihai Chen, Lin Liu, Yanning Lv, Wei Zhang, Jiandong Li, Yi Zhang, Tian Di, Shuo Zhang, Jingyuan Liu, Jie Li, Jing Qu, Wenhao Hua, Chuan Li, Peng Wang, Quanfu Zhang, Yanli Xu, Rongmeng Jiang, Qin Wang, Lijuan Chen, Shiwen Wang, Xinghuo Pang, Mifang Liang, Xuejun Ma, Xingwang Li, Quanyi Wang, Fujie Zhang, Dexin Li
Yellow fever (YF) is a viral disease endemic to the tropical regions of Africa and South America. An outbreak of YF has been occurring in Angola, since the beginning of 2016. In March 2016, a 32-year-old Chinese man who returned from Angola was hospitalized and diagnosed with the first case of imported YF in China. Clinical observations, blood viral RNA detection, serological testing and treatments for the patient were performed daily. The virus was isolated in Vero cells, and the complete viral genome was sequenced and analyzed using the next-generation genomic sequencing platform...
2016: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/27161204/scrub-typhus-masquerading-as-acute-pancreatitis
#7
Amit Chaturvedi, Monica Gupta, Shweta Bhardwaj, Dipti Handa
The clinical spectrum of scrub typhus ranges from mild to fatal depending on the virulence of bacterial strain, susceptibility of the host and promptness with which treatment is started. We report a case of a 14-year-old child with scrub typhus who developed acute pancreatitis. On serological confirmation, doxycycline therapy was started. The patient responded well and had no complications on follow-up. This case report highlights the importance of recognising an uncommon presentation of this common tropical disease, and its prompt diagnosis and early treatment for prevention of serious complications of the condition...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/26894117/acute-pancreatitis-in-a-patient-with-complicated-falciparum-malaria
#8
Bhupen Barman, Prasanta Kumar Bhattacharya, Kryshan G Lynrah, Tony Ete, Neel Kanth Issar
Malaria is one of the most common protozoan diseases, especially in tropical countries. The clinical manifestation of malaria, especially falciparum malaria varies from mild acute febrile illness to life threatening severe systemic complications involving one or more organ systems. We would like to report a case of complicated falciparum malaria involving cerebral, renal, hepatic system along with acute pancreatitis. The patient was successfully treated with anti malarial and other supportive treatment. To the best of our knowledge there are very few reports of acute pancreatitis due to malaria...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26870134/disorders-associated-with-malabsorption-of-iron-a-critical-review
#9
REVIEW
Muhammad Saboor, Amtuz Zehra, Khansa Qamar, Moinuddin
Malabsorption is a disorder of the gastrointestinal tract that leads to defective digestion, absorption and transport of important nutrients across the intestinal wall. Small intestine is the major site where most of the nutrients are absorbed. There are three main mechanisms of malabsorption; premucosal, mucosal and postmucosal. Premucosal malabsorption is the inadequate digestion due to improper mixing of gastrointestinal enzymes and bile with chyme. This could be because of surgical resection of the small intestine or a congenital deficiency of the enzymes and bile responsible for digestion e...
November 2015: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/26784911/association-analysis-of-prss1-prss2-and-cldn2-morc4-variants-in-nonalcoholic-chronic-pancreatitis-using-tropical-calcific-pancreatitis-as-model
#10
Sumit Paliwal, Seema Bhaskar, D Nageshwar Reddy, G Venkat Rao, Varghese Thomas, Shivaram Prasad Singh, Giriraj Ratan Chandak
OBJECTIVE: Association of PRSS1-PRSS2 (rs10273639) and CLDN2-MORC4 (rs12688220 and rs7057398) variants with alcohol-related chronic pancreatitis (CP) is established but with nonalcoholic CP is unclear. We addressed this inconsistency using tropical calcific pancreatitis (TCP) as model. METHODS: We sequenced 5'-UTR of PRSS1 and genotyped CLDN2-MORC4 variants in 555 patients with TCP and 801 controls and performed association analysis. Gene-gene interaction between PRSS1 and CLDN2-MORC4 variants and with p...
September 2016: Pancreas
https://www.readbyqxmd.com/read/26778456/bioactive-compounds-of-aristotelia-chilensis-stuntz-and-their-pharmacological-effects
#11
Valeria Romanucci, Daniele D'Alonzo, Annalisa Guaragna, Cinzia Di Marino, Sergio Davinelli, Giovanni Scapagnini, Giovanni Di Fabio, Armando Zarrelli
Aristotelia chilensis ([Molina], Stuntz) a member of the family Eleocarpaceae, is a plant native to Chile that is distributed in tropical and temperate Asia, Australia, the Pacific Area, and South America. The juice of its berries has important medicinal properties, as an astringent, tonic, and antidiarrhoeal. Its many qualities make the maqui berry the undisputed sovereign of the family of so-called "superfruits", as well as a valuable tool to combat cellular inflammation of bones and joints. Recently, it is discovered that the leaves of the maqui berry have important antibacterial and antitumour activities...
2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/26586139/clinical-profile-of-panin-lesions-in-tropical-chronic-pancreatitis
#12
R S Sindhu, G Parvathy, K Fysal, M K Jacob, S Geetha, B Krishna, Bonny Natesh, Ramesh Rajan
BACKGROUND: Chronic pancreatitis (CP) found in the tropical countries is known to have a higher risk for carcinoma of the pancreas. This study aimed to explore the clinical profile of pancreatic intraepithelial neoplasia (PanIN), one of the precursors of carcinoma of the pancreas, in tropical CP and to identify the possible clinical predictors of the same. METHODOLOGY: A retrospective study was done enrolling patients who underwent either Frey's procedure or pancreatic resection for symptomatic CP, between January 2008 and December 2012...
November 2015: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/26472503/fibrocalculous-pancreatic-diabetes
#13
Poorani Goundan, Ana Junqueira, Donna Kelleher-Yassen, Devin Steenkamp
The aim of this paper is to review the relevant literature related to the epidemiology, pathophysiology, natural history, clinical features and treatment of fibrocalculous pancreatic diabetes (FCPD). We review the English-language literature on this topic published between 1956 and 2014. FCPD is a form of diabetes usually associated with chronic calcific pancreatitis. It has been predominantly, though not exclusively, described in lean, young adults living in tropical developing countries. Historically linked to malnutrition, the etiology of this phenotype has not been clearly elucidated, nor has there been a clear consensus on specific diagnostic criteria or clinical features...
March 2016: Minerva Endocrinologica
https://www.readbyqxmd.com/read/26240102/an-unusual-cause-of-pancreatitis-in-a-46-year-old-returning-traveller
#14
Dominic Pimenta, Naghum Dawood
A 46-year-old previously fit and well man, travelled to Jhelum, Pakistan for 6 weeks in early 2015. Four weeks after returning to the UK, he developed sudden onset epigastric pain, vomiting and fever. C reactive protein was 232 mg/L and amylase was 2061 U/L. He was treated conservatively as pancreatitis, with peripancreatic streaking and left colic gutter fluid on a CT abdominal scan. He was discharged and later attended the Hospital for Tropical Diseases, after coughing up an 8 cm male ascaris worm. He was treated for acute ascariasis infection, complicated by resolved mild-moderate pancreatitis, a common complication in the developing world but rarely seen among travellers...
2015: BMJ Case Reports
https://www.readbyqxmd.com/read/26181373/acute-hemorrhagic-necrotizing-pancreatitis-in-falciparum-malaria
#15
José Felipe Reoyo Pascual, Carlos Cartón-Hernández, Xandra Valero-Cerrato, Raquel León-Miranda, Esther García Plata-Polo, Rosa María Martínez-Castro, Miguel Ángel Álvarez-Rico, Francisco Javier Sánchez-Manuel
Malaria is a pathology caused by a parasite called Plasmodium, characteristic of tropical countries. The most frequent symptomatology includes cerebral malaria, jaundice, convulsive crisis, anemia, hypoglycemia, kidney failure and metabolic asidosis, among others. We are presenting the case of a patient diagnosed with malaria who suffered from acute necrotizing hemorrhagic pancreatitis and evolved poorly, as an example of this combination of symptoms, rarely found in our country.
May 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/26012320/time-trends-in-the-etiology-of-chronic-pancreatitis-in-south-india
#16
Gopalakrishna Rajesh, Banavara Narasimhamurthy Girish, Suprabha Panicker, Vallath Balakrishnan
BACKGROUND: Recent reports indicate a decline in prevalence of classical tropical chronic pancreatitis (TCP). We studied the etiologies and risk factors over a 14-year period at a tertiary care university hospital. METHODS: We compared the etiology in chronic pancreatitis (CP) patients presenting and followed-up in our Pancreas Clinic over two time periods (2000-06 and 2007-13). RESULTS: Idiopathic chronic pancreatitis (ICP) was the predominant etiology seen over the two time periods...
July 2014: Tropical Gastroenterology: Official Journal of the Digestive Diseases Foundation
https://www.readbyqxmd.com/read/25958034/scanning-electron-microscopic-analysis-of-pancreatic-tissue-in-alcoholic-and-tropical-chronic-pancreatitis
#17
R S Sindhu, Raveendran Subhash, Parvathy Gireesan, Laila Raji, Peter Koshy, Bonny Natesh, Ramesh Rajan, A P Kuruvilla
INTRODUCTION: Chronic Pancreatitis (CP) is a heterogenous disease with alcoholic chronic pancreatitis (ACP) dominating in the West, and idiopathic or tropical chronic pancreatitis (TCP) in the tropics. The aim of this study is to assess the feasibility of using a scanning electron microscope (SEM) to analyze the ultra-structural changes in alcoholic and tropical subtypes of CP. METHODS: Chronic pancreatitis tissue samples were taken from the biopsy samples of 16 patients (seven ACP and nine TCP) who underwent drainage procedures for CP...
May 2015: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/25937765/pancreatic-cancer-in-chronic-pancreatitis
#18
Puneet Dhar, S Kalghatgi, Vivek Saraf
Data exists to indicate a definite association between chronic pancreatitis and pancreatic cancer. The strength of this association varies between various causes of pancreatitis, with hereditary and tropical pancreatitis more likely to result in malignancy. Pathogenesis may involve genetic factors, diabetes, smoking and alcohol consumption. Clinically a significant overlap exists between the two conditions, with histology difficult to obtain and interpret in this setting. Biomarkers like CA19-9 and others may be useful, as is a variety of newer imaging modalities...
March 2015: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/25924662/fibrocalculous-pancreatic-diabetes-a-case-report
#19
Dissanayake Mudiyanselage Priyantha Udaya Kumara Ralapanawa, Kushalee Poornima Jayawickreme, Ekanayake Mudiyanselage Madhushanka Ekanayake
BACKGROUND: Diabetes is now becoming a major cause of morbidity and mortality in both developing and developed countries. Even though type 1 and type 2 are the commonest, diabetes mellitus due to secondary causes have been identified. Fibrocalculous Pancreatic Diabetes is a unique entity wherein pancreatic calcification and chronic inflammation lead to exocrine and endocrine failure of the pancreas. This form of non-alcoholic pancreatopathy is exclusively seen among the young, with a male preponderance and commonly in tropical countries where malnutrition and poverty go hand in hand...
April 30, 2015: BMC Research Notes
https://www.readbyqxmd.com/read/25921768/contribution-of-musa-paradisiaca-in-the-inhibition-of-%C3%AE-amylase-%C3%AE-glucosidase-and-angiotensin-i-converting-enzyme-in-streptozotocin-induced-rats
#20
Sidiqat A Shodehinde, Adedayo O Ademiluyi, Ganiyu Oboh, Afolabi A Akindahunsi
AIMS: Unripe plantain based-diets are part of folklore remedy for the management of diabetes in tropical Africa; however, with the dearth of information on the rationale behind this practice; this study therefore, sought to investigate the antihyperglycemic effect of traditional unripe plantain products (Amala and Booli) in high fat fed/low dose streptozotocin-induced diabetic rats and to provide a possible rationale for their antidiabetic properties. MAIN METHODS: Diabetes was induced experimentally by high fat fed/low dose streptozotocin-diabetic rats (25mg/kg body wt...
July 15, 2015: Life Sciences
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