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chronic calcific pancreatitis

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https://www.readbyqxmd.com/read/29847323/current-role-of-endoscopic-pancreatoscopy
#1
Corey S Miller, Yen-I Chen
PURPOSE OF REVIEW: To provide an overview of the field of pancreatoscopy and to summarize the data informing its clinical utility. RECENT FINDINGS: Regarding the technological advance of pancreatoscopy, recent studies are the first to report the use of digital, single-operator pancreatoscopy (SpyGlass DS; Boston Scientific, Natick, MA). New data on the use of preoperative pancreatoscopy offer promising results for the potential to optimize treatment of intraductal papillary mucinous neoplasms and to differentiate between benign and malignant pancreatic strictures...
May 29, 2018: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/29805684/multi-modality-imaging-features-distinguish-pancreatic-carcinoma-from-mass-forming-chronic-pancreatitis-of-the-pancreatic-head
#2
Zhibing Ruan, Jun Jiao, Dingyu Min, Jinhuan Qu, Jing Li, Jing Chen, Qi Li, Chunhong Wang
The present study retrospectively analyzed computerized tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography-computerized tomography (PET/CT) data to identify features that may distinguish pancreatic carcinoma (PC) from mass-forming chronic pancreatitis (MFCP) of the pancreatic head. The mean diameter of the lesions was larger in the MFCP patients (n=24) than in the PC patients (n=30; 5.44±27 vs. 3.34±1.23 cm; P<0.001). PC lesions showed increased lobulation when compared with the MFCP cases (83...
June 2018: Oncology Letters
https://www.readbyqxmd.com/read/29742705/earlier-surgery-improves-outcomes-from-painful-chronic-pancreatitis
#3
Nengwen Ke, Dan Jia, Wei Huang, Quentin M Nunes, John A Windsor, Xubao Liu, Robert Sutton
The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes.Clinical course, Izbicki pain scores, and pancreatic function were retrospectively compared and analyzed between patients undergoing either early or late surgery (< 3 or ≥ 3 years from diagnosis) for painful CP in a single center from 2007 to 2012.The early surgery group (n = 98) more frequently than the late group (n = 199) had abdominal pain with jaundice (22.4% vs 9.5%, P = .002) and pancreatic mass +/- ductal dilatation (47% vs 27%, P < ...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29684668/endoscopic-versus-surgical-drainage-treatment-of-calcific-chronic-pancreatitis
#4
Li Jiang, Deng Ning, Qi Cheng, Xiao-Ping Chen
BACKGROUND: Endoscopic therapy and surgery are both conventional treatments to remove pancreatic duct stones that developed during the natural course of chronic pancreatitis. However, few studies comparing the effect and safety between surgery drainage and endoscopic drainage (plus Extracorporeal Shock Wave Lithotripsy, ESWL).The aim of this study was to compare the benefits between endoscopic and surgical drainage of the pancreatic duct for patients with calcified chronic pancreatitis...
April 21, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29620654/successful-endoscopic-removal-of-a-rare-large-impacted-pancreatic-duct-stone-using-grasping-forceps-a-case-report-with-video
#5
Qin Liu, Yiping Wang, Hongze Zeng, Bing Hu
RATIONALE: As a main complication of chronic pancreatitis (CP), pancreatic duct stones (PDSs) are often associated with ductal obstruction resulting in increasing intraductal and parenchymal pressure and long-lasting pain. There are many methods for removing PDSs. However, for large stones, it is technically difficult to remove them entirely by endoscopic retrograde cholangiopancreatography (ERCP). PATIENT CONCERNS: A 57-year-old man presented with a chief complaint of severe epigastric pain radiating to his back 3 or 4 times annually for 2 years...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29579746/good-agreement-between-transabdominal-and-endoscopic-ultrasound-of-the-pancreas-in-chronic-pancreatitis
#6
Trond Engjom, Khahn Do-Chong Pham, Friedemann Erchinger, Ingfrid Salvesen Haldorsen, Odd Helge Gilja, Georg Dimcevski, Roald Flesland Havre
PURPOSE:  We aimed to evaluate the agreement of single criteria and dedicated scores from transabdominal ultrasound of the pancreas (US) compared to standards by endoscopic ultrasound (EUS) and computed tomography (CT). MATERIALS AND METHODS:  In this observational cohort study performed in a tertiary care center, US and EUS were performed in 110 patients referred for suspected CP. Based on the Mayo score, 52 patients were diagnosed with CP. The sonographic findings obtained by both methods were registered...
March 26, 2018: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29560664/routine-histopathological-study-of-cholecystectomy-specimens-useful-a-retrospective-study-of-1960-cases
#7
Faten Limaiem, Asma Sassi, Ghofran Talbi, Saâdia Bouraoui, Sabeh Mzabi
BACKGROUND AND AIMS: Traditionally, a gallbladder removed for presumed benign disease is sent for histopathological examination, but this practice has been the subject of controversy. AIM: The aim of this study was to assess the usefulness of routine histopathological examination of cholecystectomy specimens and its impact on the management of patients. PATIENTS AND METHODS: The histopathological reports of 1960 patients who underwent cholecystectomy from January 2011 to November 2016 were retrospectively reviewed...
July 2017: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/29521951/metastatic-pancreatic-adenocarcinoma-in-a-patient-with-chronic-calcific-pancreatitis-and-a-heterozygous-spink1-c-194-2t-c-mutation
#8
Tina Boortalary, Niloofar Y Jalaly, Robert A Moran, Martin A Makary, Christi Walsh, Anne Marie Lennon, Atif Zaheer, Vikesh K Singh
No abstract text is available yet for this article.
April 2018: Pancreas
https://www.readbyqxmd.com/read/29513169/routine-histopathological-study-of-cholecystectomy-specimens-useful-a-retrospective-study-of-1960-cases
#9
F Limaiem, A Sassi, G Talbi, S Bouraoui, S Mzabi
BACKGROUND AND AIMS: Traditionally, a gallbladder removed for presumed benign disease is sent for histopathological examination, but this practice has been the subject of controversy. The aim of this study was to assess the usefulness of routine histopathological examination of cholecystectomy specimens and its impact on the management of patients. PATIENTS AND METHODS: he histopathological reports of 1960 patients who underwent cholecystectomy from January 2011 to November 2016 were retrospectively reviewed...
July 2017: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/29320323/multimodality-imaging-including-dual-energy-ct-in-the-evaluation-of-gallbladder-disease
#10
Lisa Ratanaprasatporn, Jennifer W Uyeda, Jeremy R Wortman, Ian Richardson, Aaron D Sodickson
Imaging of the gallbladder has a key role in the examination of patients with abdominal pain-especially pain localized to the right upper quadrant. Pathologic conditions that affect the gallbladder include cholelithiasis and associated complications such as acute and chronic cholecystitis, choledocholithiasis, gallstone pancreatitis, and cancer. Modalities used to image the gallbladder include ultrasonography (US), computed tomography (CT), magnetic resonance (MR) imaging, and nuclear scintigraphy. US is the primary imaging modality used to evaluate entities suspected of being gallbladder disease, as it is both sensitive and specific for demonstrating gallstones, biliary duct dilatation, and inflammatory features...
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29319261/synchronous-dual-primary-malignancies-of-liver-and-pancreas-with-colonic-metastasis-an-unique-presentation
#11
Nitin R Gaikwad, Sudhir J Gupta, Amol R Samarth, Tushar H Sankalecha
Synchronous appearance of the primary gastrointestinal malignancies is rare. Coexistence of primary pancreatic and hepatocellular carcinoma as synchronous malignancy is even rarer. We report a case of such combination in a 50 year old female who presented with bleeding per rectum and while evaluating we found simultaneous appearance of primary malignancies of pancreas, liver and solitary colonic metastasis from the pancreas in the background of chronic calcific pancreatitis. To the best of our knowledge this combination of synchronous pancreatic and hepatocellular carcinoma and colonic metastasis from the pancreas is unique...
October 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29249409/palpable-pancreatic-duct-due-to-pancreatic-head-mass-in-a-patient-with-chronic-calcific-pancreatitis
#12
Harshal S Mandavdhare, Pankaj Gupta, Vishal Sharma
No abstract text is available yet for this article.
January 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29231795/quantification-of-parenchymal-calcifications-in-chronic-pancreatitis-relation-to-atrophy-ductal-changes-fibrosis-and-clinical-parameters
#13
Pernille Lykke Andersen, Adnan Madzak, Søren Schou Olesen, Asbjørn Mohr Drewes, Jens Brøndum Frøkjaer
OBJECTIVES: Parenchymal calcifications are considered a hallmark finding of chronic pancreatitis (CP), but little is known about its relation to the clinical presentation and other morphological features such as atrophy, fibrosis and ductal changes. The aim was to quantify the number and maximal size of parenchymal calcifications assessed on computed tomography (CT) and to explore the association with other CT and magnetic resonance imaging (MRI)-based pancreatic features and clinical parameters...
February 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29221631/a-population-based-evaluation-of-the-natural-history-of-chronic-pancreatitis
#14
Jorge D Machicado, Suresh T Chari, Lawrence Timmons, Gong Tang, Dhiraj Yadav
BACKGROUND: Based on reports from tertiary care centers, chronic pancreatitis (CP) is considered to be a painful and debilitating disease frequently requiring invasive interventions. Our primary aim was to assess the natural course of CP in a population-based cohort using endoscopic and surgical interventions as surrogates for disease aggressiveness. METHODS: We identified all patients (n = 89, alcoholic [ACP = 46], non-alcoholic [NACP] = 43) with newly diagnosed definite CP from Olmsted County, Minnesota between 1977 and 2006...
January 2018: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/29081212/low-serum-pancreatic-amylase-and-lipase-values-are-simple-and-useful-predictors-to-diagnose-chronic-pancreatitis
#15
Hyoung-Chul Oh, Chang-Il Kwon, Ihab I El Hajj, Jeffrey J Easler, James Watkins, Evan L Fogel, Lee McHenry, Stuart Sherman, Michelle K Zimmerman, Glen A Lehman
Background/Aims: This study aimed to evaluate the diagnostic role of low serum amylase and lipase values in the detection of chronic pancreatitis. Methods: Patients underwent endoscopic retrograde cholangiopancreatography and were diagnosed with non-calcific chronic pancreatitis (NCCP; n=99) and calcific chronic pancreatitis (CCP; n=112). Patient serum amylase and lipase values were compared with those of healthy controls (H; n=170). Results: The median serum amylase (normal range, 19 to 86 U/L) and lipase values (7 to 59 U/L) (P₂₅-P₇₅) were 47...
November 15, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28952013/acinar-cell-carcinoma-in-the-background-of-chronic-calcific-pancreatitis
#16
Santhosh Anand, Sandip Chandrasekar, Biju Pottakkat, Meyyappa Devan Rajagopal, Bhawana Badhe
No abstract text is available yet for this article.
September 27, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28936758/mucinous-cystic-neoplasms-of-the-pancreas-high-resolution-cross-sectional-imaging-features-with-clinico-pathologic-correlation
#17
Alejandro Garces-Descovich, Kevin Beker, Manuel Castillo-Angeles, Alexander Brook, Elena Resnick, Shweta Shinagare, Robert M Najarian, Koenraad J Mortele
PURPOSE: To describe the high-resolution cross-sectional (MDCT/MRI) features of mucinous cystic neoplasms (MCN) of the pancreas with clinico-pathologic correlation; to identify imaging predictors of high-grade dysplasia/carcinoma; and to estimate MCN growth rate. MATERIALS AND METHODS: Thirty-two women (mean age: 46; range, 25-79 years) with resected MCN who underwent preoperative MDCT (n = 20) or MRI (n = 12) examinations over a 14-year period were included...
June 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/28902786/diagnosing-chronic-pancreatitis-comparison-and-evaluation-of-different-diagnostic-tools
#18
Yama Issa, Hjalmar C van Santvoort, Susan van Dieren, Marc G Besselink, Marja A Boermeester, Usama Ahmed Ali
OBJECTIVES: This study aims to compare the M-ANNHEIM, Büchler, and Lüneburg diagnostic tools for chronic pancreatitis (CP). METHODS: A cross-sectional analysis of the development of CP was performed in a prospectively collected multicenter cohort including 669 patients after a first episode of acute pancreatitis. We compared the individual components of the M-ANNHEIM, Büchler, and Lüneburg tools, the agreement between tools, and estimated diagnostic accuracy using Bayesian latent-class analysis...
October 2017: Pancreas
https://www.readbyqxmd.com/read/28880010/chronic-pancreatitis
#19
REVIEW
Jorg Kleeff, David C Whitcomb, Tooru Shimosegawa, Irene Esposito, Markus M Lerch, Thomas Gress, Julia Mayerle, Asbjørn Mohr Drewes, Vinciane Rebours, Fatih Akisik, J Enrique Domínguez Muñoz, John P Neoptolemos
Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental and/or other risk factors who develop persistent pathological responses to parenchymal injury or stress. Potential causes can include toxic factors (such as alcohol or smoking), metabolic abnormalities, idiopathic mechanisms, genetics, autoimmune responses and obstructive mechanisms. The pathophysiology of chronic pancreatitis is fairly complex and includes acinar cell injury, acinar stress responses, duct dysfunction, persistent or altered inflammation, and/or neuro-immune crosstalk, but these mechanisms are not completely understood...
September 7, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28821411/diagnosis-and-treatment-in-chronic-pancreatitis-an-international-survey-and-case-vignette-study
#20
Yama Issa, Hjalmar C van Santvoort, Paul Fockens, Marc G Besselink, Thomas L Bollen, Marco J Bruno, Marja A Boermeester
BACKGROUND: The aim of the study was to evaluate the current opinion and clinical decision-making process of international pancreatologists, and to systematically identify key study questions regarding the diagnosis and treatment of chronic pancreatitis (CP) for future research. METHODS: An online survey, including questions regarding the diagnosis and treatment of CP and several controversial clinical case vignettes, was send by e-mail to members of various international pancreatic associations: IHPBA, APA, EPC, ESGE and DPSG...
November 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
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