keyword
https://read.qxmd.com/read/38496839/bibliometric-analysis-of-systematic-review-and-meta-analysis-on-diabetic-foot-ulcer
#1
JOURNAL ARTICLE
Yanyan Wang, Cong Wang, Lei Zheng
Many clinical management strategies have been proposed to deal with diabetic foot ulcers. However, the occurrence and recurrence of foot ulcers remain the major problems for diabetics. This study aims to identify, visualize, and characterize the meta-analyses on diabetic foot ulcer research. Articles published online were retrieved from the Web of Science core collection database using a search query incorporating MeSH terms and topics related to diabetic foot ulcers and meta-analysis. The publications were then analyzed for basic characteristics, including publication year, countries, topics covered, references, and keywords discussed in the articles...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38490537/thromboelastography-with-platelet-mapping-identifies-high-platelet-reactivity-is-associated-with-obesity-diabetes-and-thrombotic-events
#2
JOURNAL ARTICLE
Ryan Hall, Sasha Suarez, Monica Majumdar, Ivy Lee, Nikolaos Zacharias, Denise Gee, Anahita Dua
OBJECTIVE: Identify prothrombotic coagulation profiles associated with diabetes and obesity using Thromboelastography SUMMARY BACKGROUND DATA: Metabolic comorbidities such as diabetes and obesity are considered pro-inflammatory states which theoretically increase the risk of perioperative thrombotic events across many surgical disciplines. Currently, there is a paucity of objective metrics to determine such risk and ideal pharmacologic targets. Thromboelastography with Platelet Mapping (TEG-PM) provides a comprehensive profile of coagulation and may provide insight into clot dysregulation...
March 13, 2024: Annals of Vascular Surgery
https://read.qxmd.com/read/38486275/association-between-triglyceride-glucose-index-and-intracranial-extracranial-atherosclerotic-stenosis-findings-from-a-retrospective-study
#3
JOURNAL ARTICLE
Yu Xie, Kuan Cen, Bitang Dan, Li Zou, Lei Zhang, Renwei Zhang, Huagang Li, Qi Cai, Nadire Aiziretiaili, Zhenxing Liu, Yumin Liu
OBJECTIVE: The association of the triglyceride-glucose (TyG) index with intracranial atherosclerotic stenosis (ICAS) and extracranial atherosclerotic stenosis (ECAS) is unclear. This study aimed to investigate the relationship of TyG index with the distribution and severity of ICAS and ECAS. METHOD: Patients who underwent digital subtraction angiography (DSA) for evaluating ICAS/ECAS in Zhongnan Hospital of Wuhan University from January 2017 to October 2021 were retrospectively enrolled in our study...
March 14, 2024: Cardiovascular Diabetology
https://read.qxmd.com/read/38477463/improving-diabetic-wound-healing-outcomes-with-topical-growth-factor-therapies-systematic-review-and-network-meta-analysis-of-randomised-controlled-trials
#4
JOURNAL ARTICLE
Andrew Yew Wei Wong, Natalie Ming Foong Hooi, Brian Sheng Yep Yeo, Rehena Sultana, Yong Mong Bee, Ainsley Ryan Yan Bin Lee, Sook Muay Tay
CONTEXT: Diabetes mellitus is associated with morbid complications such as diabetic foot ulcers (DFUs) that may lead to amputations or mortality if not managed adequately. OBJECTIVE: New adjunctive interventions to treat diabetic wounds include topical biologics and growth factors. This study aims to evaluate their efficacy in improving wound healing outcomes and safety. DATA SOURCES: Comprehensive database searches of MEDLINE via PubMed, EMBASE and Cochrane performed from inception to December 2022...
March 13, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38473735/special-issue-of-pathogenesis-of-pregnancy-related-complications-2023
#5
EDITORIAL
Ilona Hromadnikova
This Special Issue mainly focuses on preeclampsia (PE), haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome, gestational diabetes mellitus (GDM), foetal growth restriction (FGR), small-for-gestational-age foetuses (SGA), miscarriage, stillbirth, first-episode psychosis (FEP) during pregnancy, and pregnancy-related acute kidney injury (PR-AKI) [...].
February 20, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38472402/cluster-analysis-of-patient-characteristics-treatment-modalities-renal-impairments-and-inflammatory-markers-in-diabetes-mellitus
#6
JOURNAL ARTICLE
Milena Cojic, Aleksandra Klisic, Amina Sahmanovic, Nemanja Petrovic, Gordana Kocic
Type 2 diabetes mellitus (T2DM) is caused by an interplay of various factors where chronic hyperglycemia and inflammation have central role in its onset and progression. Identifying patient groups with increased inflammation in order to provide more personalized approach has become crucial. We hypothesized that grouping patients into clusters according to their clinical characteristics could identify distinct unique profiles that were previously invisible to the clinical eye. A cross-sectional record-based study was performed at the Primary Health Care Center Podgorica, Montenegro, on 424 T2DM patients aged between 30 and 85...
March 12, 2024: Scientific Reports
https://read.qxmd.com/read/38459941/sakuranetin-ameliorates-streptozotocin-induced-diabetes-in-rodents-by-inhibiting-caspase-3-activity-modulating-hematological-parameters-and-suppressing-inflammatory-cytokines-a-molecular-docking-and-dynamics-study
#7
JOURNAL ARTICLE
Hassan H Almasoudi, Mohammed H Nahari, Abdulkarim S Binshaya, Mohammed Ageeli Hakami, Abdulfattah Y Alhazmi, Humood Al Shmrany, Abdullah Alqasem, Farhan R Khan
Diabetes affects people of all ages, regardless of gender and background. To date, there is no evidence for the effect of sakuranetin against the streptozotocin (STZ)-induced diabetes paradigm. The research was directed to evaluate the antidiabetic activity of sakuranetin in the STZ model invoking the diabetes-induced disease paradigm. STZ (I.P. 60 mg/kg) is directed to induce type 2 diabetes in experimental rats. Recent research pursued to regulate the anti-diabetic ability of sakuranetin at both 10 and 20 mg/kg in STZ-induced rats...
March 9, 2024: Journal of Biomolecular Structure & Dynamics
https://read.qxmd.com/read/38459494/impact-of-chronic-psychological-stress-on-platelet-membrane-fatty-acid-composition-in-a-rat-model-of-type-1-diabetes-mellitus
#8
JOURNAL ARTICLE
Inga Bikulčienė, Justinas Baleišis, Eglė Mazgelytė, Romualdas Rudys, Rūta Vosyliūtė, Renata Šimkūnaitė-Rizgelienė, Arvydas Kaminskas, Dovilė Karčiauskaitė
BACKGROUND: Chronic stress and diabetes mellitus are highly associated with oxidative stress and inflammation, resulting in cell membrane disruption and platelet activity. This study aims to evaluate the impact of chronic psychological stress on the composition of the platelet phospholipid membrane and platelet activation in type 1 diabetes mellitus (T1DM). METHODS: We enrolled 35 mature healthy female Wistar rats and randomly divided them into 4 groups, namely the control group (n = 9), stress group (n = 10), T1DM group (n = 8), and T1DM + Stress group (n = 8)...
March 8, 2024: Lipids in Health and Disease
https://read.qxmd.com/read/38457693/biomimetic-micrornas-selenium-nanocomposites-for-targeted-and-combined-hyperlipidemia-therapy
#9
JOURNAL ARTICLE
Tong Li, Libing Liu, Kongdi Zhu, Yun Luo, Xin Huang, Yulan Dong, Jiaqiang Huang
Hyperlipidemia is considered as a high-risk factor for leading to type 2 diabetes mellitus and coronary heart disease, and with a significant decrease in blood selenium (Se) concentration in patients. MicroRNA-148a-3p (miR-148a-3p) inhibitor is a new and potential therapeutic target to bind low-density lipoprotein cholesterol receptors (LDLR) for decreasing the levels of low-density lipoprotein cholesterol in plasma. However, the therapeutics effects are not ideal in clinical translation of nucleic acids treatment, owing to the instability of the structure and short circulation time in vivo...
March 8, 2024: Advanced Healthcare Materials
https://read.qxmd.com/read/38447955/type-2-diabetes-platelets-and-long-term-metabolic-control-as-estimated-from-glycosylated-haemoglobin-hba1c
#10
JOURNAL ARTICLE
M Edvardsson, M Oweling, P Järemo
In type 2 diabetes, platelets are likely affected by impaired long-term glycaemic control, but such pathophysiological links are poorly understood. This study thus compares platelet reactivity (i.e. agonist-evoked platelet reactions) in vitro with glycosylated haemoglobin (HbA1c), a measure commonly used for monitoring long-term metabolic control of type 2 diabetes. Elders with type 2 diabetes ( n  = 35) were divided according to HbA1c into groups (HbA1c-low and high) consisting of 17 and 18 subjects, respectively...
March 6, 2024: Hämostaseologie
https://read.qxmd.com/read/38447019/predictive-factors-for-decompensating-events-in-cirrhotic-patients-with-primary-biliary-cholangitis-under-different-lines-of-therapy
#11
JOURNAL ARTICLE
Javier Ampuero, Ana Lucena, Marina Berenguer, Manuel Hernández-Guerra, Esther Molina, Judith Gómez-Camarero, Carlos Valdivia, Elena Gómez, Marta Casado, Carmen Álvarez-Navascuez, Francisco Jorquera, Luisa García-Buey, Álvaro Díaz-González, Rosa Morillas, Montserrat García-Retortillo, Jose Manuel Sousa, Indhira Pérez-Medrano, Miguel Ángel Simón, Javier Martínez, Juan Arenas, María Carlota Londoño, Antonio Olveira, Conrado Fernández-Rodríguez
BACKGROUND AIMS: The landscape in primary biliary cholangitis (PBC) has changed with the advent of second-line treatments. However, the use of obeticholic acid (OCA) and fibrates in PBC-related cirrhosis is challenging. We assessed the impact of receiving a second-line therapy as a risk factor for decompensated cirrhosis in a real-world cirrhotic PBC population, and identify the predictive factors for decompensated cirrhosis in these patients. APPROACH RESULTS: Multicenter study enrolling 388 PBC-cirrhotic patients from the Spanish ColHai registry...
March 6, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://read.qxmd.com/read/38445169/development-of-serum-lactate-level-based-nomograms-for-predicting-diabetic-kidney-disease-in-type-2-diabetes-mellitus-patients
#12
JOURNAL ARTICLE
Chunxia Jiang, Xiumei Ma, Jiao Chen, Yan Zeng, Man Guo, Xiaozhen Tan, Yuping Wang, Peng Wang, Pijun Yan, Yi Lei, Yang Long, Betty Yuen Kwan Law, Yong Xu
PURPOSE: To establish nomograms integrating serum lactate levels and traditional risk factors for predicting diabetic kidney disease (DKD) in type 2 diabetes mellitus (T2DM) patients. PATIENTS AND METHODS: A total of 570 T2DM patients and 100 healthy subjects were enrolled. T2DM patients were categorized into normal and high lactate groups. Univariate and multivariate logistic regression analyses were employed to identify independent predictors for DKD. Then, nomograms for predicting DKD were established, and the model performance was evaluated using the area under the receiver operating characteristic curve (AUC), calibration, and decision curve analysis (DCA)...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38443857/the-association-between-new-inflammation-markers-and-frequent-peritoneal-dialysis-associated-peritonitis
#13
JOURNAL ARTICLE
Jing Tang, Dongxue Wang, Yun Chen, Jinhong Feng
OBJECTIVE: To validate an association between new inflammation and frequent peritoneal dialysis-associated peritonitis (PDAP). MATERIALS AND METHODS: In China, retrospective clinical data were collected on 208 patients who received continuous ambulatory peritoneal dialysis (CAPD) between 2010 and 2021. The patients were divided into two groups: non-frequent PDAP (the interval between two peritonitis episodes of more than one year) and frequent PDAP (the interval between two peritonitis episodes of less than one year)...
March 5, 2024: BMC Nephrology
https://read.qxmd.com/read/38442926/-construction-and-verification-of-a-nomogram-of-factors-influencing-the-risk-of-death-in-patient-with-sepsis-associated-thrombocytopenia
#14
JOURNAL ARTICLE
Chao Gu, Han Wang, Yanxiu Li, Quan Cao, Xiangrong Zuo
OBJECTIVE: To construct a nomogram prediction model for predicting the risk of death in patients with sepsis-associated thrombocytopenia (SAT) in intensive care unit (ICU) for early indentification and active intervention. METHODS: Clinical data of SAT patients admitted to ICU of the First Affiliated Hospital of Nanjing Medical University from December 2019 to August 2021 were retrospectively collected, including demographic data, laboratory indicators, etc. According to the prognosis at 28 days, the patients were divided into the death group and the survival group, and the differences of clinical variables between the two groups were compared...
February 2024: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/38438431/assessment-of-wound-healing-activity-in-diabetic-mice-treated-with-a-novel-therapeutic-combination-of-selenium-nanoparticles-and-platelets-rich-plasma
#15
JOURNAL ARTICLE
Rania A Karas, Shaimaa Alexeree, Hassan Elsayed, Yasser A Attia
Diabetic wound healing is sluggish, often ending in amputations. This study tested a novel, two-punch therapy in mice-Selenium nanoparticles (Se NPs) and platelet-rich plasma (PRP)-to boost healing. First, a mouse model of diabetes was created. Then, Se NPs were crafted for their impressive antioxidant and antimicrobial powers. PRP, packed with growth factors, was extracted from the mice's blood. Wound healing was tracked for 28 days through photos, scoring tools, and tissue analysis. Se NPs alone spurred healing, and PRP added extra fuel...
March 4, 2024: Scientific Reports
https://read.qxmd.com/read/38431644/mean-platelet-volume-mpv-as-new-marker-of-diabetic-macrovascular-complications-in-patients-with-different-glucose-homeostasis-platelets-in-cardiovascular-risk
#16
JOURNAL ARTICLE
Velia Cassano, Giuseppe Armentaro, Domenico Iembo, Sofia Miceli, Teresa V Fiorentino, Elena Succurro, Maria Perticone, Franco Arturi, Marta L Hribal, Tiziana Montalcini, Francesco Andreozzi, Giorgio Sesti, Arturo Pujia, Angela Sciacqua
BACKGROUND: Platelets play an important role in the development of cardiovascular disease (CVD). Mean platelet volume (MPV) is considered as biological marker of platelets activity and function. The aim of the present study was to evaluate MPV values and its possible correlation with arterial stiffness and subclinical myocardial damage, in normal glucose tolerance patients (NGT), in newly diagnosed type 2 diabetic (T2DM) patients and in individuals with pre-diabetes. METHODS: We enrolled 400 newly diagnosed hypertensive patients...
March 2, 2024: Cardiovascular Diabetology
https://read.qxmd.com/read/38430149/research-progress-in-the-relationship-between-trimethylamine-oxide-and-coronary-heart-disease
#17
JOURNAL ARTICLE
Honghui Kong, Jinming Cen, Xili Yang, Zhaoyan Xu, Jingrong Liang, Qingyuan Xiong, Jiayi Zhu
OBJECTIVE: To provide a theoretical basis for intestinal intervention in the treatment of coronary heart disease. METHODS: Summarizing the mechanism of trimethylamine oxide (TMAO) inducing coronary heart disease and discussing the target of clinical intervention including TMAO generation, metabolism, and other links. The authors also clarified the potential clinical value of TMAO as a predictor of cardiovascular disease.. RESULTS: The intestinal microbiota metabolite TMAO is closely related to the occurrence and development of coronary heart disease...
March 1, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38426227/can-system-inflammation-response-index-or-systemic-immune-inflammation-index-predict-gestational-diabetes-mellitus-in-the-first-trimester-a-prospective-observational-study
#18
JOURNAL ARTICLE
Esra Gulen Yildiz, Atakan Tanacan, Gulcan Okutucu, Ayse Gulcin Bastemur, Goksun Ipek, Dilek Sahin
OBJECTIVE: To evaluate System Inflammation Response Index (SIRI) and Systemic Immune Inflammation Index (SII), which are the inflammatory indices, for the prediction of gestational diabetes mellitus (GDM) in the first trimester. METHODS: This was a prospective observational study conducted in a tertiary center from April 2023 to September 2023. Ninety-four pregnant women with gestational diabetes and 107 healthy pregnant women were included. The two groups were compared according to first-trimester SIRI and SII values...
March 1, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38420847/potential-protein-signatures-for-recurrence-prediction-of-ischemic-stroke
#19
JOURNAL ARTICLE
Chengyi Zhang, Yang Liu, Huimin Zhu, Xinying Huang, Cang Guo, Si Cheng, Meng Yuan, Yong Jiang, Xia Meng, S Claiborne Johnston, Yongjun Wang, Wei-Na Jin, Fu-Dong Shi
BACKGROUND: Acute ischemic stroke is a major cause of mortality and disability worldwide, with approximately 7.4% to 7.7% recurrence within the first 3 months. This study aimed to identify potential biomarkers for predicting stroke recurrence. METHODS AND RESULTS: We conducted a nested case-control study using a hospital-based cohort from the Third China National Stroke Registry selecting 214 age- and sex-matched patients with ischemic stroke with hypertension and no history of diabetes or heart disease...
February 29, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38419854/accuracy-of-prognostic-serological-biomarkers-in-predicting-liver-fibrosis-severity-in-people-with-metabolic-dysfunction-associated-steatotic-liver-disease-a-meta-analysis-of-over-40-000-participants
#20
Sergio M López Tórrez, Camila O Ayala, Paula Bayer Ruggiro, Caroline Abud Drumond Costa, Mario B Wagner, Alexandre Vontobel Padoin, Rita Mattiello
INTRODUCTION: A prognostic model to predict liver severity in people with metabolic dysfunction-associated steatotic liver disease (MASLD) is very important, but the accuracy of the most commonly used tools is not yet well established. OBJECTIVE: The meta-analysis aimed to assess the accuracy of different prognostic serological biomarkers in predicting liver fibrosis severity in people with MASLD. METHODS: Adults ≥18 years of age with MASLD were included, with the following: liver biopsy and aspartate aminotransferase-to-platelet ratio (APRI), fibrosis index-4 (FIB-4), non-alcoholic fatty liver disease fibrosis score (NFS), body mass index, aspartate aminotransferase/alanine aminotransferase ratio, diabetes score (BARD score), FibroMeter, FibroTest, enhanced liver fibrosis (ELF), Forns score, and Hepascore...
2024: Frontiers in Nutrition
keyword
keyword
78061
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.