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https://www.readbyqxmd.com/read/29922935/imaging-spectrum-of-bing-neel-syndrome-how-can-a-radiologist-recognise-this-rare-neurological-complication-of-waldenstr%C3%A3-m-s-macroglobulinemia
#1
Aikaterini Fitsiori, Luc-Matthieu Fornecker, Laurence Simon, Alexandros Karentzos, Damien Galanaud, Olivier Outteryck, Patrick Vermersch, Jean-Pierre Pruvo, Emmanuel Gerardin, Christine Lebrun-Frenay, Francois Lafitte, Jean-Philippe Cottier, Christine Clerc, Jerome de Seze, Jean-Louis Dietemann, Stephane Kremer
OBJECTIVES: Bing-Neel syndrome (BNS) is a rare neurological complication of Waldenström's macroglobulinemia. The aim of this study is to describe the spectrum of radiological manifestations of this syndrome and their prevalence in order to facilitate its early diagnosis. METHODS: Twenty-four patients with BNS were diagnosed between 1994 and 2016 in eight centres in France. We retrospectively examined the medical records of these patients as well as the corresponding literature, focusing on imaging studies...
June 19, 2018: European Radiology
https://www.readbyqxmd.com/read/29912656/neurological-impairments-in-hypoxic-neonates-and-lactate-levels
#2
Miljana Z Jovandaric, Svetlana J Milenkovic
INTRODUCTION: Metabolic acidosis with increasing lactate concentration develops due to the lack of oxygen in the tissues. OBJECTIVES: The effect of lactic acidosis on neurological development in the first year of life. MATERIALS AND METHODS: Our study included 50 newborns with perinatal hypoxia requiring oxygen therapy and 50 healthy newborns. pH, pCO2, pO2, base excess (BE) and lactates from arterialized capillary blood were determined in both groups of newborns, in the first and second hours after birth, and neurological development in the first year of life was estimated...
June 18, 2018: Neurological Research
https://www.readbyqxmd.com/read/29911601/oral-oxycodone-for-pain-after-caesarean-section-a-randomized-comparison-with-nurse-administered-iv-morphine-in-a-pragmatic-study
#3
Boel Niklasson, Catarina Arnelo, Susanne Georgsson Öhman, Märta Segerdahl, Agneta Blanck
Background and aims The present randomized open label parallel group study was conducted to evaluate if an oral oxycodone (OXY) regimen can be at least equally effective and as safe for postoperative analgesia after caesarean section (CS) as a standard of care program using nurse-administered intravenous morphine (IVM), followed by oral codeine. Methods Eighty women (40 + 40) were scheduled for elective CS under spinal anaesthesia. All patients received postoperative multimodal analgesic therapy, including ibuprofen and paracetamol...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29911023/cavernous-sinus-syndrome-in-dogs-and-cats-case-series-2002-2015
#4
Aslynn M Jones, Ellison Bentley, Helena Rylander
The cavernous sinus (CS) is a paired venous sinus that runs along either side of the pituitary gland on the floor of the calvarium. Cavernous sinus syndrome (CSS) refers to deficits in more than one of the cranial nerves III, IV, V, and VI, as they are in close association in this region. The purpose of this study was to identify the presenting complaints, neurologic findings, diagnosis, and outcomes in dogs and cats with confirmed cavernous sinus syndrome (CSS). Medical records between 2002 and 2015 were reviewed...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29909560/rhinencephalon-changes-in-tuberous-sclerosis-complex
#5
Renzo Manara, Davide Brotto, Samuela Bugin, Maria Federica Pelizza, Stefano Sartori, Margherita Nosadini, Sara Azzolini, Giorgio Iaconetta, Cecilia Parazzini, Alessandra Murgia, Angela Peron, Paola Canevini, Francesca Labriola, Aglaia Vignoli, Irene Toldo
PURPOSE: Despite complex olfactory bulb embryogenesis, its development abnormalities in tuberous sclerosis complex (TSC) have been poorly investigated. METHODS: Brain MRIs of 110 TSC patients (mean age 11.5 years; age range 0.5-38 years; 52 female; 26 TSC1, 68 TSC2, 8 without mutation identified in TSC1 or TSC2, 8 not tested) were retrospectively evaluated. Signal and morphological abnormalities consistent with olfactory bulb hypo/aplasia or with olfactory bulb hamartomas were recorded...
June 17, 2018: Neuroradiology
https://www.readbyqxmd.com/read/29906575/sodium-fluorescein-video-angiography-fl-vag-as-an-adjunct-to-resection-of-cerebral-arteriovenous-malformations
#6
Serrano-Rubio Alejandro, Ruiz-Treviño Armando S, Orenday-Barraza Jose M, Vázquez-Gregorio Rafael, Lee Angel, Nathal Edgar
OBJECT: The use of intraoperative fluorescence has proven to be a useful tool in multiple neurosurgical procedures with a potential utility in treating arteriovenous malformations (AVMs). The aim of this study was to characterize dynamic changes of an AVM using a microscope-integrated technique at the moment of performing an intraoperative Sodium fluorescein videoangiography (FL-VAG) at each of the resection phases. METHODS: Our study at the National Institute of Neurology and Neurosurgery-Mexico City, prospectively recruited twelve patients harboring an AVM, using FL-VAG as an ancillary technique for the resection of the lesion...
June 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29901537/an-evidence-based-approach-to-the-management-of-children-with-morquio-a-syndrome-presenting-with-craniocervical-pathology
#7
Nicole Williams, Alessandro Narducci, Deborah M Eastwood, Maureen Cleary, Dominic Thompson
STUDY DESIGN: Retrospective case series OBJECTIVE.: To review clinical and radiological outcomes of craniovertebral surgery in children with Morquio A syndrome (Mucopolysaccharidosis type IVA) and develop an evidence-based management algorithm. SUMMARY OF BACKGROUND DATA: Myelopathy secondary to craniovertebral pathology is a common cause of neurological disability in Morquio A syndrome. Previously unresolved surgical controversies include the value of surveillance, surgical indications and operative technique...
June 12, 2018: Spine
https://www.readbyqxmd.com/read/29901457/cystic-intestinal-pneumatosis-of-the-small-gut-etiopathogenesis-and-review-of-literature
#8
Luca Napolitano, Mathew Waku, Gustavo Maggi, Franco Ciarelli
Cystic intestinal pneumatosis (CIP) is the presence of gas bubbles inside the wall of the intestine. In literature it has been reported to be associated with a variety of clinical conditions such as: superior mesenteric ischemia, intestinal perforation, bowel necrosis, infections which can cause mucosal alterations and therefore increasing its permeability, necrotizing enterocolitis in babies, trauma, intestinal obstruction, autoimmune and pulmonary pathologies. Its presence is usually documented by radiological techniques such as abdominal X-ray, CT scan and endoscopy and are usually characterized by the typical pattern of gas bubbles in the wall of the intestine...
March 19, 2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29899773/phenylketonuria-our-experience-in-nine-years-at-a-tertiary-level-referral-institute
#9
Sadanandvalli R Chandra, Rita Christopher, Mane M Daryappa, Rashmi Devaraj
Introduction: Phenyl ketonuria is an inborn error of amino acid metabolism resulting in excessive phenyl alanine levels in blood resulting in a spectrum of neurological defects. Patients and Methods: We retrospectively went through the records of patients diagnosed as Phenyl ketonuria in the last nine years in our team and patients who's data could be accessed were analyzed in detail. Details of laboratory tests, imaging clinical features, course were recorded. Observation: A total of 32 patients were identified in nine years of which data was available only for 15 patients...
January 2018: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29891069/immune-mediated-ataxias
#10
Bastien Joubert, Kevin Rostásy, Jérôme Honnorat
Immune-mediated cerebellar ataxia (CA) comprises a group of rare diseases that are still incompletely described, and are probably underdiagnosed. Both acute and progressive progressions are possible. Different syndromes have been identified, including CA associated with anti-GAD antibodies, the cerebellar type of Hashimoto encephalopathy, primary autoimmune CA, gluten ataxia, opsoclonus-myoclonus syndrome, and paraneoplastic cerebellar degenerations. Most of these syndromes are associated with autoantibodies targeting neuronal antigens...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29889708/a-prospective-observational-study-of-anesthesia-related-adverse-events-and-postoperative-complications-occurring-during-a-surgical-mission-in-madagascar
#11
Michelle C White, Brian J Barki, Stephen A Lerma, Sarah Kate Couch, Dennis Alcorn, Richard G Gillerman
BACKGROUND: Two-thirds of the world's population lack access to safe anesthesia and surgical care. Nongovernmental organizations (NGOs) play an important role in bridging the gap, but surgical outcomes vary. After complex surgeries, up to 20-fold higher postoperative complication rates are reported and the reasons for poor outcomes are undefined. Little is known concerning the incidence of anesthesia complications. Mercy Ships uses fully trained staff, and infrastructure and equipment resources similar to that of high-income countries, allowing the influence of these factors to be disentangled from patient factors when evaluating anesthesia and surgical outcomes after NGO sponsored surgery...
June 8, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29888094/predicting-neonatal-encephalopathy-from-maternal-data-in-electronic-medical-records
#12
Thomas Li, Cheng Gao, Chao Yan, Sarah Osmundson, Bradley A Malin, You Chen
Neonatal encephalopathy (NE) is a leading cause of neonatal mortality and lifetime neurological disability. The earlier the risk of NE can be assessed, the more effective interventions can be in preventing adverse outcomes. Existing studies that focus on intrapartum risk factors do not provide the early prognostic forecasting necessary to prepare healthcare professionals to intervene early in a high-risk NE case. This work used maternal data in a supervised machine learning framework to predict NE events. Specifically, we 1) collected the electronic medical records (EMRs) for 104 NE newborns and 31,054 non-NE newborns and their mothers, 2) trained and tested a regularized logistic regression on imbalanced and high-dimensional EMR data, and 3) discerned important features that could be possible risk factors...
2018: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/29882008/overview-of-therapeutic-plasma-exchange-in-pediatric-neurology-a-single-center-experience
#13
Murat Özkale, Ilknur Erol, Yasemin Özkale, İlknur Kozanoğlu
Therapeutic plasma exchange (TPE) is used in the treatment of neurological, hematological, renal and autoimmune diseases with known or suspected immune pathogenesis. In comparison with neurological diseases of adults, knowledge about the use of TPE in children is incomplete. We report our experience on TPE in children with neurological diseases in a single institution and describe the underlying etiology, clinical course, treatment and outcome. We retrospectively evaluated 22 consecutive children (12 girls, 10 boys, aged 2-16 years) who underwent TPE in the pediatric intensive care unit between January 2010 and January 2017...
June 7, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29872919/-parkinson-s-disease-alzheimer-s-disease-and-oncological-diseases-in-residential-geriatric-care-pain-frequency-and-selected-healthcare-features-in-comparison
#14
REVIEW
P Kutschar, K Lex, J Osterbrink, S Lorenzl
BACKGROUND: Adequate pain management and palliative care structures are of significant importance in residential nursing homes. Whilst professional pain treatment and palliative care measures are frequently implemented for residents with oncological diseases, this is often not the case for residents with neurological disorders. Such a potential undertreatment is even more challenging when the means of interaction and communication with affected persons are aggravated by impairments in cognitive function...
June 5, 2018: Der Schmerz
https://www.readbyqxmd.com/read/29868505/epidemiology-pathogenesis-and-control-of-a-tick-borne-disease-kyasanur-forest-disease-current-status-and-future-directions
#15
REVIEW
Syed Z Shah, Basit Jabbar, Nadeem Ahmed, Anum Rehman, Hira Nasir, Sarooj Nadeem, Iqra Jabbar, Zia Ur Rahman, Shafiq Azam
In South Asia, Haemaphysalis spinigera tick transmits Kyasanur Forest Disease Virus (KFDV), a flavivirus that causes severe hemorrhagic fever with neurological manifestations such as mental disturbances, severe headache, tremors, and vision deficits in infected human beings with a fatality rate of 3-10%. The disease was first reported in March 1957 from Kyasanur forest of Karnataka (India) from sick and dying monkeys. Since then, between 400 and 500 humans cases per year have been recorded; monkeys and small mammals are common hosts of this virus...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29865933/complex-regional-pain-syndrome-type-1-in-the-medico-legal-setting-high-rates-of-somatoform-disorders-opiate-use-and-diagnostic-uncertainty
#16
Christopher Bass, Gregory Yates
Objective The aim of this study was to review demographic and clinical characteristics of patients with complex regional pain syndrome type 1 (CRPS) seen in a UK medico-legal setting - particularly the relationship between CRPS and somatoform disorders. Methods Fifty consecutive cases of CRPS (interviewed 2005-2016) undergoing psychiatric assessment were reviewed. A systematic assessment of mental states was conducted via interview and examination of medical/psychiatric records. Thirty patients also completed the Brief Illness Perception Questionnaire (BIPQ)...
January 1, 2018: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/29865192/magnetic-resonance-imaging-and-interictal-electroencephalography-findings-in-newly-diagnosed-epileptic-children
#17
Mehmet Alp Dirik, Burcin Sanlidag
INTRODUCTION: Epilepsy is one of the most frequently diagnosed chronic neurological disorders in children. Diagnosis is often based on seizure history and electroencephalography (EEG) assessment. Magnetic resonance imaging (MRI) is recommended for etiologic workup and intervention requirements. We aimed to detect by MRI if focal structural abnormalities are present in the brain in relation to interictal epileptiform discharges (IED). MATERIAL AND METHODS: The study was designed retrospectively...
June 1, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29861191/a-large-case-series-of-successful-treatment-of-patients-exposed-to-mold-and-mycotoxin
#18
William J Rea
PURPOSE: The goal of this study was to present the results of treatment of 100 chemically sensitive and chronically mold-exposed patients, who continued to be disabled even after decontamination of their houses or work places or they were physically removed from their sources of mold. METHODS: Molds were identified, serum anti-mold immunoglobulin G antibodies were measured, patients were skin-tested, immunologic abnormalities were recorded, and objective neurologic tests were performed in a subset of patients...
May 31, 2018: Clinical Therapeutics
https://www.readbyqxmd.com/read/29861155/early-onset-encephalopathy-with-paroxysmal-movement-disorders-and-epileptic-seizures-without-hemiplegic-attacks-about-three-children-with-novel-atp1a3-mutations
#19
Pauline Marzin, Cyril Mignot, Nathalie Dorison, Louis Dufour, Dorothée Ville, Anna Kaminska, Eleni Panagiotakaki, Anne-Sophie Dienpendaele, Marie-José Penniello, Marie-Christine Nougues, Boris Keren, Christel Depienne, Caroline Nava, Mathieu Milh, Laurent Villard, Christian Richelme, Clotilde Rivier, Sandra Whalen, Delphine Heron, Gaëtan Lesca, Diane Doummar
OBJECTIVE: Heterozygous mutations in the ATP1A3 gene are responsible for various neurological disorders, ranging from early-onset alternating hemiplegia of childhood to adult-onset dystonia-parkinsonism. Next generation sequencing allowed the description of other phenotypes, including early-onset epileptic encephalopathy in two patients. We report on three more patients carrying ATP1A3 mutations with a close phenotype and discuss the relationship of this phenotype to alternating hemiplegia of childhood...
May 31, 2018: Brain & Development
https://www.readbyqxmd.com/read/29859575/pediatric-anosmia-a-case-series
#20
Leah J Hauser, Emily L Jensen, David M Mirsky, Kenny H Chan
INTRODUCTION: Little is known about the etiology of olfactory dysfunction in the pediatric population. The aim of this study is to characterize the etiology and clinical features of anosmia and to explore evaluation options in a pediatric population. METHODS: Olfactory dysfunction was identified at a tertiary pediatric hospital between January 2003 and October 2014 using a text-based and ICD-9 search of the electronic health record system. Clinical information gathered included history, physical examination and imaging study...
July 2018: International Journal of Pediatric Otorhinolaryngology
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