Golia Shafiei, Arielle S Keller, Maxwell Bertolero, Sheila Shanmugan, Dani S Bassett, Andrew A Chen, Sydney Covitz, Audrey Houghton, Audrey Luo, Kahini Mehta, Taylor Salo, Russell T Shinohara, Damien Fair, Michael N Hallquist, Theodore D Satterthwaite
BACKGROUND: Symptoms of borderline personality disorder (BPD) often manifest in adolescence, yet the underlying relationship between these debilitating symptoms and the development of functional brain networks is not well understood. Here we aimed to investigate how multivariate patterns of functional connectivity are associated with borderline personality traits in large samples of young adults and adolescents. METHODS: We used functional Magnetic Resonance Imaging (fMRI) data from young adults and adolescents from the Human Connectome Project: Young Adults (HCP-YA; N=870, ages 22-37 years, 457 female) and Development (HCP-D; N=223, ages 16-21 years, 121 female)...
March 7, 2024: Biological Psychiatry