keyword
MENU ▼
Read by QxMD icon Read
search

associated executive function symptoms

keyword
https://www.readbyqxmd.com/read/28809852/the-snp-set-based-association-study-identifies-itga1-as-a-susceptibility-gene-of-attention-deficit-hyperactivity-disorder-in-han-chinese
#1
L Liu, L Zhang, H M Li, Z R Wang, X F Xie, J P Mei, J L Jin, J Shi, L Sun, S C Li, Y L Tan, L Yang, J Wang, H M Yang, Q J Qian, Y F Wang
Genome-wide association studies, which detect the association between single-nucleotide polymorphisms (SNPs) and disease susceptibility, have been extensively applied to study attention-deficit/hyperactivity disorder (ADHD), but genome-wide significant associations have not been found yet. Genetic heterogeneity and insufficient genomic coverage may account for the missing heritability. We performed a two-stage association study for ADHD in the Han Chinese population. In the discovery stage, 1033 ADHD patients and 950 healthy controls were genotyped using both the Affymetrix Genome-Wide Human SNP Array 6...
August 15, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28797564/impact-of-anxiety-apathy-and-reduced-functional-autonomy-on-perceived-quality-of-life-in-parkinson-s-disease
#2
Alfonsina D'Iorio, Carmine Vitale, Fausta Piscopo, Chiara Baiano, Anna Paola Falanga, Katia Longo, Marianna Amboni, Paolo Barone, Gabriella Santangelo
INTRODUCTION: Parkinson's disease (PD) is characterized by a wide spectrum of non-motor symptoms that may impact negatively on the activities of the patient's daily life and reduce Health-related quality of life (HRQoL). The present study explored the impact of specific non-motor symptoms on the HRQoL in PD. METHODS: Eighty-four outpatients underwent the Montreal Cognitive Assessment (MoCA) assessing global functioning and several questionnaires to assess depression, apathy, impulse control disorders (ICD), anxiety, anhedonia and functional impact of cognitive impairment...
August 5, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28790899/sensory-processing-in-the-dorsolateral-striatum-the-contribution-of-thalamostriatal-pathways
#3
Kevin D Alloway, Jared B Smith, Todd M Mowery, Glenn D R Watson
The dorsal striatum has two functionally-defined subdivisions: a dorsomedial striatum (DMS) region involved in mediating goal-directed behaviors that require conscious effort, and a dorsolateral striatum (DLS) region involved in the execution of habitual behaviors in a familiar sensory context. Consistent with its presumed role in forming stimulus-response (S-R) associations, neurons in DLS receive massive inputs from sensorimotor cortex and are responsive to both active and passive sensory stimulation. While several studies have established that corticostriatal inputs contribute to the stimulus-induced responses observed in the DLS, there is growing awareness that the thalamus has a significant role in conveying sensory-related information to DLS and other parts of the striatum...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/28783763/mapping-altered-brain-connectivity-and-its-clinical-associations-in-adult-moyamoya-disease-a-resting-state-functional-mri-study
#4
Ken Kazumata, Khin Khin Tha, Haruto Uchino, Masaki Ito, Naoki Nakayama, Takeo Abumiya
Detection of subtle ischemic injuries in moyamoya disease may enable optimization of timing of revascularization surgery, and could potentially improve functional outcomes. Resting-state functional magnetic resonance imaging (rs-fMRI) is widely used to study functional organization of the brain, but it remains unclear whether rs-fMRI could elucidate distinct characteristics in moyamoya disease. Here, we aimed to determine changes in a conventional rs-fMRI measure and analyze any associations with clinical symptoms and cerebral hemodynamics...
2017: PloS One
https://www.readbyqxmd.com/read/28781731/neuropsychological-functioning-in-obsessive-compulsive-washers-drug-naive-without-depressive-symptoms
#5
Ali Akbar Saremi, Seyed Vahid Shariat, Mohammad Ali Nazari, Behrooz Dolatshahi
INTRODUCTION: Obsessive-Compulsive Disorder (OCD) is a complex and heterogeneous neuropsychiatric syndrome. Contamination obsessions and washing/cleaning compulsions are the most frequent clinical OCD subtypes. The current study aimed at examining the neuropsychological impairments in drug-naive obsessive-compulsive (OC) washers without depressive symptoms and their association with the severity of symptoms. METHODS: In the current causal-comparative study, 35 patients with diagnostic and statistical mental disorders class (DSM)-IV diagnosed with washing-subtype OCD and 35 healthy subjects were selected by the convenience sampling method and evaluated by computerized neuropsychology battery and clinical tests as Stroop Color-Word Test (SCWT), Wisconsin Card Sorting Test (WCST), Go/No-Go Test, Digits Forward (DF), Digits Backward (DB), Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and General Health Questionnaire (GHQ)-28...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28756343/ptsd-symptoms-are-associated-with-visual-retrieval-performance-in-oef-oif-ond-veterans
#6
Darrin M Aase, Julia A DiGangi, Joseph M Babione, Christopher Schroth, David M Levy, Amy E Kennedy, Eric Proescher, Justin E Greenstein, Robert Walters, Holly Passi, Scott A Langenecker, K Luan Phan
Posttraumatic stress disorder (PTSD) is associated with poorer performance on neuropsychological tests in veterans. However, prior studies have generally compared individuals with PTSD to control groups, often excluding individuals with moderate symptoms. The present study evaluated neuropsychological performance among OEF/OIF/OND veterans as a function of overall PTSD severity, while also exploring potential associations between cognitive performance and PTSD symptom clusters. Using a brief neuropsychological battery, clinical interviews, and self-report instruments, we evaluated neuropsychological and psychiatric functioning in 90 OEF/OIF/OND veterans...
July 24, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28755550/impact-of-early-life-adversity-and-tryptophan-depletion-on-functional-connectivity-in-menopausal-women-a-double-blind-placebo-controlled-crossover-study
#7
Sheila Shanmugan, Theodore D Satterthwaite, Mary D Sammel, Wen Cao, Kosha Ruparel, Ruben C Gur, C Neill Epperson, James Loughead
During the menopause transition, women are at increased risk of subjective symptoms of executive dysfunction. Evidence from animal and human participant studies suggests adverse childhood experiences (ACE) may be a risk factor for executive complaints during this hormonal transition. Preclinical literature indicates early life adversity effects on serotonin function may play a role in this increased susceptibility. However, the mechanisms underlying this increase in vulnerability in human participants remain relatively unknown...
July 14, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28755189/neurological-and-neuropsychological-problems-in-tyrosinemia-type-i-patients
#8
Willem G van Ginkel, Rianne Jahja, Stephan C J Huijbregts, Francjan J van Spronsen
Clinically, Hereditary Tyrosinemia type I (HTI) is especially characterized by severe liver dysfunction in early life. However, recurrent neurological crises are another main finding in these patients when they are treated with a tyrosine and phenylalanine restricted diet only. This is caused by the accumulation of δ-aminolevulinic acid due to the inhibitory effect of succinylacetone on the enzyme that metabolizes δ-aminolevulinic acid. Due to the biochemical and clinical resemblance of these neurological crises and acute intermittent porphyria, this group of symptoms in HTI patients is mostly called porphyria-like-syndrome...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28750755/evening-salivary-cortisol-and-alpha-amylase-at-14months-and-neurodevelopment-at-4years-sex-differences
#9
Ainara Andiarena, Nekane Balluerka, Mario Murcia, Jesús Ibarluzea, Vivette Glover, Oscar Vegas
Stress system activity in early life can have long-term effects on neurodevelopment. The main aim of this study was to assess the association of child evening salivary cortisol and alpha-amylase basal levels at 14months of age with longer-term neuropsychological development at 4years in a low-risk population-based birth cohort derived from the INMA (Environment and Childhood) project in Spain. We included 186 parent-children pairs with information on both stress system activity and neurodevelopment. Both stress markers at 14months of age showed an association with neuropsychological development at 4years...
July 26, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/28749606/perceived-stress-is-associated-with-increased-rostral-middle-frontal-gyrus-cortical-thickness-a-family-based-and-discordant-sibling-investigation
#10
L J Michalski, C H Demers, D A A Baranger, D M Barch, M P Harms, G C Burgess, R Bogdan
BACKGROUND: Elevated stress perception and depression commonly co-occur, suggesting that they share a common neurobiology. Cortical thickness of the rostral middle frontal gyrus (RMFG), a region critical for executive function, has been associated with depression- and stress-related phenotypes. Here, we examined whether RMFG cortical thickness is associated with these phenotypes in a large family-based community sample. METHODS: RMFG cortical thickness was estimated using FreeSurfer among participants (n=879) who completed the ongoing Human Connectome Project...
July 27, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28749232/behavioural-and-cognitive-sex-gender-differences-in-autism-spectrum-condition-and-typically-developing-males-and-females
#11
Laura Hull, William Mandy, K V Petrides
Studies assessing sex/gender differences in autism spectrum conditions often fail to include typically developing control groups. It is, therefore, unclear whether observed sex/gender differences reflect those found in the general population or are particular to autism spectrum conditions. A systematic search identified articles comparing behavioural and cognitive characteristics in males and females with and without an autism spectrum condition diagnosis. A total of 13 studies were included in meta-analyses of sex/gender differences in core autism spectrum condition symptoms (social/communication impairments and restricted/repetitive behaviours and interests) and intelligence quotient...
August 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28745216/insights-in-developmental-coordination-disorder
#12
Marie Farmer, Bernard Echenne, Regen Drouin, M Hamed Bentourkia
BACKGROUND: Developmental Coordination Disorder (DCD) is a neurological impairment occurring in nearly 6% of general population, and sometimes mimics other developmental disorders like Attention Deficit Hyperactivity Disorder (ADHD) or, in the most severe cases, intellectual deficiency. OBJECTIVE: We propose in this review a contribution on this matter in order to provide better insights in DCD including clinical symptoms and pathophysiological explanations that would identify this entity from others...
July 26, 2017: Current Pediatric Reviews
https://www.readbyqxmd.com/read/28740815/positive-schizotypy-and-negative-schizotypy-are-associated-with-differential-patterns-of-episodic-memory-impairment
#13
Lili Sahakyan, Thomas R Kwapil
Cognitive impairment is a hallmark of schizophrenia; however, studies have not comprehensively examined such impairments in non-clinically ascertained schizotypic young adults. The present study employed a series of measures to assess episodic memory in high positive schizotypy, high negative schizotypy, and comparison groups (each group n = 25). Consistent with diminished cognitive functioning seen in negative symptom schizophrenia, the negative schizotypy group exhibited deficits on free recall, recognition, and source memory tasks...
September 2016: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/28736899/trajectories-of-depressive-and-anxiety-symptoms-in-older-adults-a-6-year-prospective-cohort-study
#14
Sophie E Holmes, Irina Esterlis, Carolyn M Mazure, Yen Ying Lim, David Ames, Stephanie Rainey-Smith, Chris Fowler, Kathryn Ellis, Ralph N Martins, Olivier Salvado, Vincent Doré, Victor L Villemagne, Christopher C Rowe, Simon M Laws, Colin L Masters, Robert H Pietrzak, Paul Maruff
OBJECTIVE: Depressive and anxiety symptoms are common in older adults, significantly affect quality of life, and are risk factors for Alzheimer's disease. We sought to identify the determinants of predominant trajectories of depressive and anxiety symptoms in cognitively normal older adults. METHOD: Four hundred twenty-three older adults recruited from the general community underwent Aβ positron emission tomography imaging, apolipoprotein and brain-derived neurotrophic factor genotyping, and cognitive testing at baseline and had follow-up assessments...
July 24, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28733341/activity-limitations-and-subjective-well-being-after-stroke
#15
Darin B Zahuranec, Lesli E Skolarus, Chunyang Feng, Vicki A Freedman, James F Burke
OBJECTIVE: As limitations in activities of daily living are major components of many stroke outcome scales, we examined how well activity limitations predicted subjective well-being among stroke survivors in a nationally representative survey. METHODS: Individuals with a self-reported history of stroke were identified from the National Health and Aging Trends Study. Subjective well-being (primary outcome) was assessed with a validated 7-item measure (higher = greater well-being) assessing emotions (cheerful, bored, full of life, and upset) and self-realization (purpose in life, self-acceptance, and environmental mastery)...
July 21, 2017: Neurology
https://www.readbyqxmd.com/read/28732820/the-impact-of-cognitive-impairment-on-self-management-in-chronic-obstructive-pulmonary-disease-a-systematic-review
#16
REVIEW
Chelsea Baird, Janaka Lovell, Marilyn Johnson, Kerrie Shiell, Joseph E Ibrahim
OBJECTIVE: To determine the characteristics of persons with cognitive impairment being able to self-manage in chronic obstructive pulmonary disease (COPD). METHODS: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance this systematic review examined all studies in English from 1st January 2000 to 20 February 2016, describing the relationship between cognition and COPD self-management domains in older community dwelling persons with dementia or cognitive impairment...
August 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28723827/neurocognitive-and-symptom-trajectories-of-adhd-from-childhood-to-early-adolescence
#17
Andrea L Murray, Thomas Robinson, Gail Tripp
OBJECTIVE: This longitudinal study investigated changes in neurocognitive functioning from childhood to early adolescence in a sample of children diagnosed with DSM-IV attention-deficit hyperactivity disorder (ADHD). It also compared the neurocognitive trajectories of children who continued to meet the diagnostic criteria for ADHD at follow-up and those in partial remission. METHODS: Children diagnosed with ADHD (N = 55) were tested at baseline (M = 7.7 years, SD = 1...
July 17, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28716235/psychosis-in-parkinson-s-disease-from-the-soft-signs-to-the-hard-science
#18
REVIEW
Abhishek Lenka, Priyantha Herath, Rita Christopher, Pramod Kumar Pal
Patients with Parkinson's disease (PD) may develop a wide spectrum of non-motor symptoms during the course of illness. Psychosis is one such commonly observed non-motor symptoms of PD. Although several studies based on neuroimaging, genetics, retinal imaging, and neuropsychological evaluations have explored the pathogenesis of psychosis in PD; exact neural correlates are yet to be understood. Identification of factors related to psychosis in PD is important, as psychosis has been reported to be associated with higher rates of mortality, caregiver distress, and nursing home placements...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28715675/resting-state-brain-networks-in-patients-with-parkinson-s-disease-and-impulse-control-disorders
#19
Alessandro Tessitore, Gabriella Santangelo, Rosa De Micco, Alfonso Giordano, Simona Raimo, Marianna Amboni, Fabrizio Esposito, Paolo Barone, Gioacchino Tedeschi, Carmine Vitale
INTRODUCTION: To investigate intrinsic neural networks connectivity changes in Parkinson's disease (PD) patients with and without impulse control disorders (ICD). METHODS: Fifteen patients with PD with ICD (ICD+), 15 patients with PD without ICD (ICD-) and 24 age and sex-matched healthy controls (HC) were enrolled in the study. To identify patients with and without ICD and/or punding, we used the Minnesota Impulsive Disorders Interview (MIDI) and a clinical interview based on diagnostic criteria for each symptom...
June 24, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28713264/white-matter-changes-related-gait-and-executive-function-deficits-associations-with-age-and-parkinson-s-disease
#20
Jennifer Sartor, Kristina Bettecken, Felix P Bernhard, Marc Hofmann, Till Gladow, Tobias Lindig, Meltem Ciliz, Mara Ten Kate, Johanna Geritz, Sebastian Heinzel, Marije Benedictus, Philip Scheltens, Markus A Hobert, Walter Maetzler
Background: White matter changes (WMC) are a common finding among older adults and patients with Parkinson's disease (PD), and have been associated with, e.g., gait deficits and executive dysfunction. How the factors age and PD influence WMC-related deficits is, to our best knowledge, not investigated to date. We hypothesized that advanced age and presence of PD leads to WMC-related symptoms while practicing tasks with a low complexity level, and low age and absence of PD leads to WMC-related symptoms while practicing tasks with a high complexity level...
2017: Frontiers in Aging Neuroscience
keyword
keyword
78053
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"