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https://www.readbyqxmd.com/read/28429290/association-of-long-term-patterns-of-depressive-symptoms-and-attention-executive-function-among-older-men-with-and-without-human-immunodeficiency-virus
#1
Nicole M Armstrong, Pamela J Surkan, Glenn J Treisman, Ned C Sacktor, Michael R Irwin, Linda A Teplin, Ron Stall, Eileen M Martin, James T Becker, Cynthia Munro, Andrew J Levine, Lisa P Jacobson, Alison G Abraham
Older HIV-infected men are at higher risk for both depression and cognitive impairments, compared to HIV-uninfected men. We evaluated the association between longitudinal patterns of depressive symptoms and attention/executive function in HIV-infected and HIV-uninfected men aged 50+ years to understand whether HIV infection influenced the long-term effect of depression on attention/executive function. Responses to the Center for Epidemiologic Studies-Depression scale and attention/executive function tests (Trail Making Test Part B and Symbol Digit Modalities Test) were collected semiannually from May 1986 to April 2015 in 1611 men...
April 20, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28427035/associations-between-executive-functions-and-mental-health-outcomes-for-adults-with-autism-spectrum-disorder
#2
David Zimmerman, Tamara Ownsworth, Analise O'Donovan, Jacqueline Roberts, Matthew J Gullo
Associations between executive functions (EF) and mental-health in adults with autism spectrum disorder (ASD) were examined. Forty-two adults with ASD completed measures of EF, mood and self-concept. Better concept formation and social inference skills were significantly associated with fewer anxiety symptoms. Conversely, participants with better non-verbal reasoning, cognitive flexibility and social cognition reported more negative self-concept and lower self-esteem. Overall, individuals with impaired EF are more prone to anxiety, whereas those with stronger EF are more likely to experience negative self-concept...
April 12, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28425730/the-relation-of-anxiety-and-cognition-in-parkinson-s-disease
#3
Gretchen O Reynolds, Kristine K Hanna, Sandy Neargarder, Alice Cronin-Golomb
OBJECTIVE: Parkinson's disease (PD) has long been conceptualized as a motor disorder, but nonmotor symptoms also manifest in the disease and significantly reduce quality of life. Anxiety and cognitive dysfunction are prevalent nonmotor symptoms, even in early disease stages, but the relation between these symptoms remains poorly understood. We examined self-reported anxiety and neurocognitive function, indexed by measures of executive function (set-shifting and phonemic fluency), categorical fluency, and attention/working memory...
April 20, 2017: Neuropsychology
https://www.readbyqxmd.com/read/28425185/the-influence-of-hippocampal-atrophy-on-the-cognitive-phenotype-of-dementia-with-lewy-bodies
#4
Greg J Elder, Karen Mactier, Sean J Colloby, Rosie Watson, Andrew M Blamire, John T O'Brien, John-Paul Taylor
OBJECTIVE: The level of hippocampal atrophy in dementia with Lewy bodies (DLB) is typically less than that observed in Alzheimer's disease (AD). However, it is not known how the cognitive phenotype of DLB is influenced by hippocampal atrophy or the atrophy of adjacent medial temporal lobe structures. METHODS: Dementia with Lewy bodies (n = 65), AD (n = 76) and control (n = 63) participants underwent 3T magnetic resonance imaging and cognitive Cambridge Cognitive Examination and Mini-Mental State Examination (CAMCOG and MMSE) assessments...
April 20, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28424560/an-exploratory-study-of-host-polymorphisms-in-genes-that-clinically-characterize-breast-cancer-tumors-and-pretreatment-cognitive-performance-in-breast-cancer-survivors
#5
Theresa A Koleck, Catherine M Bender, Beth Z Clark, Christopher M Ryan, Puja Ghotkar, Adam Brufsky, Priscilla F McAuliffe, Priya Rastogi, Susan M Sereika, Yvette P Conley
PURPOSE: Inspired by the hypothesis that heterogeneity in the biology of breast cancers at the cellular level may account for cognitive dysfunction symptom variability in survivors, the current study explored relationships between host single-nucleotide polymorphisms (SNPs) in 25 breast cancer-related candidate genes (AURKA, BAG1, BCL2, BIRC5, CCNB1, CD68, CENPA, CMC2, CTSL2, DIAPH3, ERBB2, ESR1, GRB7, GSTM1, MELK, MKI67, MMP11, MYBL2, NDC80, ORC6, PGR, RACGAP1, RFC4, RRM2, and SCUBE2), identified from clinically relevant prognostic multigene-expression profiles for breast cancer, and pretreatment cognitive performance...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/28424070/antidepressant-use-and-cognitive-decline-in-community-dwelling-elderly-people-the-three-city-cohort
#6
Isabelle Carrière, Joanna Norton, Amandine Farré, Marilyn Wyart, Christophe Tzourio, Pernelle Noize, Karine Pérès, Annie Fourrier-Réglat, Karen Ritchie, Marie Laure Ancelin
BACKGROUND: Cognitive impairment is very common in late-life depression, principally affecting executive skills and information processing speed. The aim of the study was to examine the effect of antidepressant treatment on cognitive performances over a 10-year period. METHODS: The community-based cohort included 7381 participants aged 65 years and above. Five cognitive domains (verbal fluency, psychomotor speed, executive function, visuospatial skills and global cognition) were assessed up to five times over 10 years of follow-up...
April 19, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28420385/frontotemporal-dementia-as-a-comorbidity-to-idiopathic-normal-pressure-hydrocephalus-inph-a-short-review-of-literature-and-an-unusual-case
#7
V E Korhonen, E Solje, N M Suhonen, T Rauramaa, R Vanninen, A M Remes, V Leinonen
Behavioural variant frontotemporal dementia (bvFTD) and idiopathic normal pressure hydrocephalus (iNPH) are neurodegenerative diseases that can present with similar symptoms. These include decline in executive functions, psychomotor slowness, and behavioural and personality changes. Ventricular enlargement is a key radiological finding in iNPH that may also be present in bvFTD caused by the C9ORF72 expansion mutation. Due to this, bvFTD has been hypothesized as a potential comorbidity to iNPH but bvFTD patients have never been identified in studies focusing in clinical comorbidities with iNPH...
April 19, 2017: Fluids and Barriers of the CNS
https://www.readbyqxmd.com/read/28414754/type-2-diabetes-depressive-symptoms-and-trajectories-of-cognitive-decline-in-a-national-sample-of-community-dwellers-a-prospective-cohort-study
#8
Panayotes Demakakos, Graciela Muniz-Terrera, Arie Nouwen
We examined the individual and synergistic effects of type 2 diabetes and elevated depressive symptoms on memory and executive function trajectories over 10 and eight years of follow-up, respectively. Our sample comprised 10,524 community-dwellers aged ≥50 years in 2002-03 from the English Longitudinal Study of Ageing. With respect to memory (word recall), participants with either diabetes or elevated depressive symptoms recalled significantly fewer words compared with those free of these conditions (reference category), but more words compared with those with both conditions...
2017: PloS One
https://www.readbyqxmd.com/read/28414497/dual-tasking-in-parkinson-s-disease-cognitive-consequences-while-walking
#9
Robert D Salazar, Xiaolin Ren, Terry D Ellis, Noor Toraif, Olivier J Barthelemy, Sandy Neargarder, Alice Cronin-Golomb
OBJECTIVE: Cognitive deficits are common in Parkinson's disease (PD) and exacerbate the functional limitations imposed by PD's hallmark motor symptoms, including impairments in walking. Though much research has addressed the effect of dual cognitive-locomotor tasks on walking, less is known about their effect on cognition. The purpose of this study was to investigate the relation between gait and executive function, with the hypothesis that dual tasking would exacerbate cognitive vulnerabilities in PD as well as being associated with gait disturbances...
April 17, 2017: Neuropsychology
https://www.readbyqxmd.com/read/28414250/longitudinal-changes-in-brain-morphology-from-4-weeks-to-12-months-after-mild-traumatic-brain-injury-associations-with-cognitive-functions-and-clinical-variables
#10
T Hellstrom, L T Westlye, S Sigurdardottir, C Brunborg, H L Soberg, Ø Holthe, A Server, M J Lund, O A Andreassen, N Andelic
OBJECTIVE: To investigate longitudinal changes in cortical and subcortical volumes in patients with mild traumatic brain injury (MTBI) and to evaluate whether such changes were associated with self-reported post-concussive symptoms, global functional outcomes and neuropsychological functioning. METHODS: This was a prospecitve, longitudinal cohort study of patients with complicated (i.e presence of intracranial abnormalities on the day of injury CT) and uncomplicated MTBI (i...
April 17, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28414249/psychological-distress-is-associated-with-altered-cognitive-functioning-in-family-caregivers-of-patients-with-disorders-of-consciousness
#11
P Moretta, O Masotta, E Crispino, G Castronovo, S Ruvolo, C Montalbano, V Loreto, L Trojano, A Estraneo
OBJECTIVES: To analyse the possible presence of reduced cognitive efficiency in family caregivers of patients with prolonged disorders of consciousness (DOC). SUBJECTS: The participants were 27 caregivers of 25 patients with DOC admitted to the severe brain injury units of the ICS Maugeri, Institutes of Telese Terme and Sciacca, Italy. METHODS: We examined cognitive functions such as short- and long-term memory, executive functions and attention by means of standardized tests...
April 17, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28412088/tobacco-smoking-and-its-association-with-cognition-in-first-episode-psychosis-patients
#12
Lauren M Hickling, Rocio Perez-Iglesias, Victor Ortiz-García de la Foz, Vincent Balanzá-Martínez, Philip McGuire, Benedicto Crespo-Facorro, Rosa Ayesa-Arriola
Available evidence suggests that nicotine may enhance cognitive functioning. Moreover, it has been suggested that the high prevalence of smoking in people with schizophrenia is in part due to self-medication behaviour to alleviate cognitive deficits. We assessed the association between tobacco smoking and cognitive functioning in a large population of first episode psychosis (FEP) patients (n=304) and healthy controls (n=156). Smokers were not tobacco deprived, or were minimally deprived (≤2h). Verbal memory, visual memory, working memory, processing speed, executive function, motor dexterity and attention were assessed...
April 12, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28410255/neurocognitive-correlates-of-attention-deficit-hyperactivity-disorder-symptoms-in-children-born-at-extremely-low-gestational-age
#13
Megan N Scott, Scott J Hunter, Robert M Joseph, Thomas Michael OʼShea, Stephen R Hooper, Elizabeth N Allred, Alan Leviton, Karl Kuban
OBJECTIVE: Compared with children born near term, those born extremely preterm (EP) are at much higher risk for attention-deficit hyperactivity disorder (ADHD). Little information is available about differences in neuropsychological outcomes among EP children with and without ADHD. Our analyses aimed to evaluate the neuropsychological correlates of ADHD symptoms in extremely low gestational age newborns (ELGANs). METHODS: We obtained Child Symptom Inventory-4 reports from parents (n = 871) and teachers (n = 634) of 10-year-old children born before the 28th week of gestation...
April 12, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28406663/neuropsychological-correlates-of-theory-of-mind-deficits-in-patients-with-multiple-sclerosis
#14
Simona Raimo, Luigi Trojano, Simona Pappacena, Raffaella Alaia, Daniele Spitaleri, Dario Grossi, Gabriella Santangelo
BACKGROUND: Theory of mind (ToM) is the ability to understand and interpret another person's beliefs, intentions (cognitive ToM) and emotions (affective ToM). OBJECTIVE: To explore affective and cognitive ToM and their neuropsychological correlates in patients affected by multiple sclerosis (MS). MATERIAL AND METHOD: Forty MS patients and 40 matched control individuals underwent tasks assessing cognitive (the ToM Pictures Sequencing Task and the Advanced Test of ToM) and affective ToM (the Reading the Mind in the Eyes Task and the Emotion Attribution Task), in both verbal and nonverbal modality, a comprehensive neuropsychological battery, and questionnaires for behavioral disorders...
April 13, 2017: Neuropsychology
https://www.readbyqxmd.com/read/28394724/a-multimodal-nonpharmacologic-intervention-improves-mood-and-cognitive-function-in-people-with-multiple-sclerosis
#15
Jennifer E Lee, Babita Bisht, Michael J Hall, Linda M Rubenstein, Rebecca Louison, Danielle T Klein, Terry L Wahls
OBJECTIVE: The objective of this study was to examine whether participation in a 12-month multimodal intervention would improve mood and cognitive function in adults with progressive multiple sclerosis (MS). METHODS: In this one-arm, open-label feasibility trial, participants were prescribed a home-based multimodal intervention, including (1) a modified Paleolithic diet; (2) an exercise program (stretching and strengthening of the trunk and lower limb muscles); (3) neuromuscular electrical stimulation (EStim) of trunk and lower limb muscles; and (4) stress management (meditation and self-massage)...
April 10, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28394438/stimulus-processing-and-error-monitoring-in-more-able-kindergarteners-with-autism-spectrum-disorder-asd-a-short-review-and-a-preliminary-erp-study
#16
So Hyun Kim, Jennie Grammer, Nurit Benrey, Frederick Morrison, Catherine Lord
Deficits in executive functions (EF) in individuals with autism spectrum disorder (ASD) have been identified. However, there is limited evidence about patterns of deficits in EF-related skills, especially at the neurobiological level, in young children with ASD and little is known about how these skills are related to other domains of functioning and symptom severity. In this study, we provide a focused review of EF-related Event-Related Potentials (ERP) studies in children with ASD, accompanied by preliminary data for neurophysiological correlates of EF on a child-friendly Go/No-go task...
April 10, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28390447/anxiety-symptoms-and-risk-of-cognitive-decline-in-older-community-dwelling-men
#17
Ahmed M Kassem, Mary Ganguli, Kristine Yaffe, Joseph T Hanlon, Oscar L Lopez, John W Wilson, Jane A Cauley
BACKGROUND: Previous research regarding anxiety as a predictor of future cognitive decline in older adults is limited and inconsistent. We examined the independent relationship between anxiety symptoms and subsequent cognitive decline. METHODS: We included 2,818 community-dwelling older men (mean age = 76.1, SD ±5.3 years) who were followed on an average for 3.4 years. We assessed anxiety symptoms at baseline using the Goldberg Anxiety Scale (GAS; range = 0-9)...
April 9, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28383930/sluggish-cognitive-tempo-in-adults-psychometric-validation-of-the-adult-concentration-inventory
#18
Stephen P Becker, G Leonard Burns, Annie A Garner, Matthew A Jarrett, Aaron M Luebbe, Jeffery N Epstein, Erik G Willcutt
As interest in sluggish cognitive tempo (SCT) increases, a primary limitation for the field is the lack of a unified set of symptoms for assessing SCT. No existing SCT measure includes all items identified in a recent meta-analysis as optimal for distinguishing between SCT and attention-deficit/hyperactivity disorder (ADHD) inattention. This study evaluates a new self-report measure for assessing SCT in adulthood, the Adult Concentration Inventory (ACI), which was developed in response to the meta-analytic findings for assessing SCT...
April 6, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28380342/association-of-subjective-memory-complaint-and-depressive-symptoms-with-objective-cognitive-functions-in-prodromal-alzheimer-s-disease-including-pre-mild-cognitive-impairment
#19
Eun Hyun Seo, Hoowon Kim, Kyu Yeong Choi, Kun Ho Lee, Il Han Choo
BACKGROUND: Subjective memory complaints (SMC) and depressive symptoms (SDS) are common in the elderly population. However, the relationship among SMC, SDS, and cognitive function remains unclear. We investigated these associations in the elderly from cognitively normal (CN), pre-mild cognitive impairment (MCI), and amnestic MCI (aMCI) groups. METHODS: Participants (CN, 299; pre-MCI, 106; aMCI, 267) underwent comprehensive clinical and neuropsychological assessment...
March 30, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28380108/the-relationship-between-moderate-to-vigorous-physical-activity-and-executive-function-among-individuals-with-schizophrenia-differences-by-illness-duration
#20
Viviane Grassmann, Mehala Subramaniapillai, Mark Duncan, Kelly Arbour-Nicitopoulos, Guy E Faulkner
Objective: Schizophrenia is a chronic mental illness characterized by positive and negative symptoms. Cognitive impairment continues to be a core and consistent deficit. Previous studies have shown that physical activity (PA) is positively associated with cognitive performance. Thus, it may play a supportive role in mitigating cognitive impairments among individuals with schizophrenia. The aim of this study was to analyze the relationship between moderate-to-vigorous physical activity (MVPA) and executive function among adults with schizophrenia...
March 30, 2017: Revista Brasileira de Psiquiatria
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