keyword
https://read.qxmd.com/read/38536468/traumatic-rhabdomyolysis-rare-but-morbid-potentially-lethal-and-inconsistently-monitored
#1
JOURNAL ARTICLE
Thomas Giles, Kate King, Simone Meakes, Natasha Weaver, Zsolt J Balogh
PURPOSE: Although traumatic rhabdomyolysis (TR) is shown to be associated with acute kidney injury (AKI), there are no large prospective epidemiological studies, interventional trials, official guidelines outlining the appropriate investigation, monitoring, and treatment on this poorly understood condition. We aimed to establish the contemporary epidemiology and describe current practices for TR to power future higher quality studies. We hypothesised that investigation and monitoring occur in an ad hoc fashion...
March 27, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38533491/identification-of-novel-blood-based-extracellular-vesicles-biomarker-candidates-with-potential-specificity-for-traumatic-brain-injury-in-polytrauma-patients
#2
JOURNAL ARTICLE
Cora R Schindler, Jason A Hörauf, Birte Weber, Inna Schaible, Ingo Marzi, Dirk Henrich, Liudmila Leppik
OBJECTIVE: The goal of this study was to identify changes in extracellular vesicles (EV) surface proteins specific to traumatic brain injury (TBI), which could be used as a diagnostic and prognostic tool in polytrauma patients. SUMMARY BACKGROUND DATA: Known serum TBI-specific biomarkers (S100B, NSE, and GFAP), which can predict the severity and outcome of isolated TBI, lose their predictive value in the presence of additional extracranial injuries. Extracellular vesicles (EVs) are released from cells in response to various stimuli and carry specific cargo/surface molecules that could be used for tracking injury-responding cells...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38529315/treatment-approach-for-coexisting-chest-wall-fractures-and-unstable-thoracolumbar-spine-fractures-in-polytrauma-patients-requiring-prone-spine-surgery
#3
EDITORIAL
Aymen Alqazzaz, Zan Naseer, Carl A Beyer, Jeremy W Cannon, Amrit Khalsa
Concomitant chest wall fractures (sternal and/or rib fractures) with unstable thoracolumbar fractures that require surgical fixation are rare but highly morbid injuries that mandate a multidisciplinary approach to treatment. There is limited evidence in the literature regarding optimal timing and order of surgical fixation of these patients with multiple injuries. Here, we present our experience with two patients at a single institution that demonstrates the challenges that present with this patient population...
2024: Trauma Surgery & Acute Care Open
https://read.qxmd.com/read/38524103/beaver-tail-liver-and-congenital-asplenia-in-a-polytrauma-patient
#4
JOURNAL ARTICLE
Ahmad Alrahmani, Sharfuddin Chowdhury
No abstract text is available yet for this article.
2024: Pan African Medical Journal
https://read.qxmd.com/read/38521635/the-paediatric-polytrauma-ct-indication-pepci-score-development-of-a-prognostic-model-to-reduce-unnecessary-ct-scans-in-paediatric-trauma-patients
#5
JOURNAL ARTICLE
Strahl André, Willemsen Jan Fritjof, Schoof Benjamin, Reinshagen Konrad, Frosch Karl-Heinz, Wintges Kristofer
BACKGROUND: Whole-Body CT (WBCT) is frequently used in emergency situations for promptly diagnosing paediatric polytrauma patients, given the challenges associated with obtaining precise details about the mechanism and progression of trauma. However, WBCT does not lead to reduced mortality in paediatric patients, but is associated with high radiation exposure. We therefore wanted to develop a screening tool for CT demand-driven emergency room (ER)-trauma diagnostic to reduce radiation exposure in paediatric patients...
March 11, 2024: Injury
https://read.qxmd.com/read/38517382/pathophysiology-of-severe-burn-injuries-new-therapeutic-opportunities-from-a-systems-perspective
#6
JOURNAL ARTICLE
Geoffrey P Dobson, Jodie L Morris, Hayley L Letson
Severe burn injury elicits a profound stress response with the potential for high morbidity and mortality. If polytrauma is present, patient outcomes appear to be worse. Sex-based comparisons indicate females have worse outcomes than males. There are few effective drug therapies to treat burn shock and secondary injury progression. The lack of effective drugs appears to arise from the current treat-as-you-go approach rather than a more integrated systems approach. In this review, we present a brief history of burns research and discuss its pathophysiology from a systems' perspective...
March 22, 2024: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://read.qxmd.com/read/38512418/evaluation-of-management-of-ct-scan-proved-solid-organ-injury-in-blunt-injury-abdomen-a-prospective-study
#7
JOURNAL ARTICLE
Sourodip Mukharjee, Dinesh B V, Bharath S V
BACKGROUND: Trauma especially road traffic injury is one of the major health-related issues throughout the world, especially in developing countries like India (Mattox 2022). Solid organ injury is the most common cause of morbidity and mortality in patients with blunt abdominal trauma. The non-operative management (NOM) is being consistently followed for hemodynamically stable patients with respect to solid organ injuries. This study aims to provide an evidence base for management modalities of solid organ injuries in blunt abdominal trauma...
March 21, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38510367/from-diagnosis-to-therapy-the-acute-traumatic-hemothorax%C3%A2-an-orientation-for-young-surgeons
#8
REVIEW
Romina M Rösch
INTRODUCTION: This review aims to provide an overview of diagnosing and managing traumatic haemothorax for young surgeons. CONTENT: Of 27,333 polytrauma patients in Germany in 2021, 35 % were admitted with thoracic trauma. In polytrauma patients, chest injuries are an independent negative predictor of 30-day mortality. These patients should be treated in an evidence-based and standardized manner to reduce mortality and morbidity. There are several methods of immediate diagnosis that should be used depending on hemodynamic stability...
December 2023: Innovative Surgical Sciences
https://read.qxmd.com/read/38509185/burn-or-trauma-scoring-experience-of-the-burn-unit-of-the-queen-astrid-military-hospital-during-the-terror-attacks-on-22-march-2016
#9
JOURNAL ARTICLE
Lotte Bruyninckx, Serge Jennes, Jean-Paul Pirnay, Jean-Charles de Schoutheete
PURPOSE: On 22 March 2016, the burn unit (BU) of Queen Astrid Military Hospital assessed a surge in severely injured victims from terror attacks at the national airport and Maalbeek subway station according to the damage control resuscitation (DCR) and damage control surgery (DCS) principles. This study delves into its approach to identify a suitable triage scoring system and to determine if a BU can serve as buffer capacity for mass casualty incidents (MCIs). METHODS: The study reviewed retrospectively the origin of explosion, demographic data, sustained injuries, performed surgery, and length of stay of all admitted patients...
March 20, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38506517/does-scheduled-low-dose-short-term-nsaid-ketorolac-modulate-cytokine-levels-following-orthopaedic-polytrauma-a-secondary-analysis-of-a-randomized-clinical-trial
#10
JOURNAL ARTICLE
Jeffrey A Foster, Gregory S Hawk, David C Landy, Jarod T Griffin, Andrew C Bernard, Douglas R Oyler, Wyatt G S Southall, Maaz Muhammad, Carlos R Sierra-Arce, Samuel D Mounce, Jacob S Borgida, Lusha Xiang, Arun Aneja
OBJECTIVES: To determine whether scheduled low-dose, short-term ketorolac modulates cytokine concentrations in orthopaedic polytrauma patients. DESIGN: Secondary analysis of a double-blinded, randomized controlled trial. SETTING: Single Level I trauma center from August 2018 to October 2022. PATIENT SELECTION CRITERIA: Orthopaedic polytrauma patients between 18-75 years with a New Injury Severity Score greater than 9 were enrolled...
March 20, 2024: Journal of Orthopaedic Trauma
https://read.qxmd.com/read/38504340/the-latissimus-dorsi-creates-a-dynamic-track-for-the-inferior-angle-of-the-scapula-during-arm-abduction-in-humans
#11
JOURNAL ARTICLE
Alp Paksoy, Doruk Akgün, Henry Gebauer, Daniel Karczewski, Lucca Lacheta, John M Tokish, Aaron Chamberlain, Philipp Moroder
BACKGROUND: The importance of several scapulothoracic muscles, including trapezius and serratus anterior, in maintaining physiological scapula kinematics has been highlighted in the past. However, the relationship between the scapula and the latissimus dorsi muscle remains unclear. Our clinical surgical observation is that the latissimus dorsi does not directly attach but rather runs superficial to the inferior angle of the scapula. Based on this observation, we hypothesise that the latissimus dorsi creates a dynamic track on which the scapula glides under the muscle belly during elevation of the arm, creating the latissimus-scapula overlap (LSO)...
March 20, 2024: Journal of Orthopaedic Surgery and Research
https://read.qxmd.com/read/38492981/recovery-of-functional-independence-following-major-burn-a-systematic-review
#12
REVIEW
Ali M Jawad, Murtaza Kadhum, Janine Evans, Jonathan J Cubitt, Niall Martin
BACKGROUND: Major burn injury, despite advancements in care and prevention, can have a profound impact on long-term morbidity, affecting quality of life and socioeconomic standing. We aim to explore factors predicting recovery of independence, the expected rate and time in majorly burned patients, and the measures of progress used. METHOD: A systematic search of four databases (MEDLINE, EMBASE, COCHRANE, CINAHL) was conducted for studies reporting outcomes pertaining to physical ability indicative of independent function in adult (>15 y) cohorts who had suffered a major burn (>20% TBSA) up to 30 years after treatment in a developed specialised burn service...
February 27, 2024: Burns
https://read.qxmd.com/read/38492727/stroke-prevention-in-blunt-cerebrovascular-injury-role-of-aspirin-81-mg
#13
JOURNAL ARTICLE
Sina Asaadi, Christopher B Khoury, Julia Han, Martin G Rosenthal, Allen G Murga, Justin Dye, Kaushik Mukherjee, Miguel Lopez-Gonzalez, Ian Kershisnik, Marie L Crandall, Maryam B Tabrizi
BACKGROUND: The stroke rate in blunt cerebrovascular injury (BCVI) varies from 25% without treatment to less than 8% with antithrombotic therapy (ATT). There is no consensus on the optimal management to prevent stroke BCVI. We investigated the efficacy and safety of oral Aspirin (ASA) 81 mg to prevent BCVI-related stroke compared to historically reported stroke rates with ASA 325 mg and heparin. METHOD: A single-center retrospective study included adult trauma patients who received oral ASA 81 mg for BCVI management between 2013 and 2022...
March 14, 2024: Annals of Vascular Surgery
https://read.qxmd.com/read/38487403/the-local-and-systemic-effects-of-immune-function-on-fracture-healing
#14
REVIEW
Andrew R Evans, Peter V Giannoudis, Philip Leucht, Todd O McKinley, Greg E Gaski, Katherine P Frey, Joseph C Wenke, Christopher Lee
The immune system plays an integral role in the regulation of cellular processes responsible for fracture healing. Local and systemic influences on fracture healing correlate in many ways with fracture-related outcomes, including soft tissue healing quality and fracture union rates. Impaired soft tissue healing, restricted perfusion of a fracture site, and infection also in turn affect the immune response to fracture injury. Modern techniques used to investigate the relationship between immune system function and fracture healing include precision medicine, using vast quantities of data to interpret broad patterns of inflammatory response...
March 2024: OTA international: the open access journal of orthopaedic trauma
https://read.qxmd.com/read/38487400/preclinical-models-of-orthopaedic-trauma-orthopaedic-research-society-ors-and-orthopaedic-trauma-association-ota-symposium-2022
#15
JOURNAL ARTICLE
Patrick M Wise, Augustine M Saiz, Justin Haller, Joseph C Wenke, Thomas Schaer, Prism Schneider, Saam Morshed, Chelsea S Bahney
Orthopaedic trauma remains a leading cause of patient morbidity, mortality, and global health care burden. Although significant advances have been made in the diagnosis, treatment, and rehabilitation of these injuries, complications such as malunion, nonunion, infection, disuse muscle atrophy and osteopenia, and incomplete return to baseline function still occur. The significant inherent clinical variability in fracture care such as differing patient demographics, injury patterns, and treatment protocols make standardized and replicable study, especially of cellular and molecular based mechanisms, nearly impossible...
March 2024: OTA international: the open access journal of orthopaedic trauma
https://read.qxmd.com/read/38476412/short-segment-percutaneous-fusion-versus-open-posterior-fusion-with-screw-in-the-fractured-vertebra-for-thoracolumbar-junction-burst-vertebral-fracture-treatment
#16
JOURNAL ARTICLE
Andrea Perna, Andrea Franchini, Franco Lucio Gorgoglione, Felice Barletta, Biagio Moretti, Andrea Piazzolla, Maria Beatrice Bocchi, Calogero Velluto, Francesco Tamburrelli, Luca Proietti
OBJECTIVES: The treatment options for thoracolumbar junction burst fractures remain a topic of controversy. Short-segment percutaneous fixation (SSPF) and short-segment open fixation including the fractured level (SSOFIFL) are both viable procedures for managing these fractures. At present, there is a lack of evidence in the literature demonstrating the absolute superiority of one treatment over the other. This study aimed to compare these two surgical strategies with a focus on radiological and clinical outcomes...
2024: Journal of Neurosciences in Rural Practice
https://read.qxmd.com/read/38471125/polytrauma-in-children%C3%A2-epidemiology-acute-diagnostic-evaluation-and-treatment
#17
REVIEW
Monica Christine Ciorba, Marc Maegele
BACKGROUND: Inadequate clinical experience still causes uncertainty in the acute diagnostic evaluation and treatment of polytrauma in children (with or without coagulopathy). This review deals with the main aspects of the acute care of severely injured children in the light of current guidelines and other relevant literature, in particular airway control, volume and coagulation management, acute diagnostic imaging, and blood coagulation studies in the shock room. METHODS: This review is based on literature retrieved by a selective search in PubMed, Medline (OVIDSP), the Cochrane Central Register of Controlled Trials, and Epistemonikos covering the period January 2001 to August 2023...
May 17, 2024: Deutsches Ärzteblatt International
https://read.qxmd.com/read/38470653/polytrauma-caused-by-a-bear-attacking-a-human-with-a-benign-outcome
#18
Ruslan Mellin, Ellina Velichko, Larisa Maltseva, Sergey Dydykin, Yuriy Vasil'ev
Injuries to humans caused by wild animals, particularly bears, are rarely mentioned in the literature. Such injuries are frequent in Siberia, which is a territory surrounded by dense forests inhabited by brown bears. In the last 4 months alone (September-December 2023), four bear attacks on humans were registered in Khakassia, Russia. This article presents a clinical case of rehabilitating a patient after a bear attack, who suffered multiple fragmentary fractures of the facial skeleton with displaced bone fragments, subcutaneous emphysema of the soft tissues of the face, damage to the parietal and right occipital regions and paranasal sinus hemorrhage on the left side...
February 24, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38468587/post-traumatic-fracture-dislocation-of-the-humeral-head-with-intrathoracic-migration-a-case-report
#19
JOURNAL ARTICLE
Rym Hamed, Aymen Zoubli, Hanène Ghazali, Imen Mekki, Amel Maaref, Siwar Jerbi
INTRODUCTION: Severe trauma is a frequent condition encountered in Emergency department (ED) in which vital prognosis can easily be engaged. This condition could be responsible for unusual injuries occurrence. Emergency physician must be aware of these situations where adequate management is urgently required. We report a case of e 45-year-old patient who was admitted to the ED after a high velocity road traffic accident resulting in multiple injuries and fracture dislocation and migrating humeral head into intra thoracic position...
November 5, 2023: La Tunisie Médicale
https://read.qxmd.com/read/38461482/tranexamic-acid-in-trauma-after-3-hours-from-injury-when-is-it-safe-and-effective-to-use-again
#20
JOURNAL ARTICLE
Christopher D Barrett, Matthew D Neal, Jonathan G Schoenecker, Robert L Medcalf, Paul S Myles
Tranexamic acid (TXA) has proven mortality benefit if used early after traumatic injury, likely related to a combination of bleeding reduction and other non-bleeding effects. If TXA is given more than 3 h after traumatic injury, there is a significant and paradoxical increased risk of death due to bleeding. TXA has level 1 evidence for use as a bleeding reduction agent in isolated orthopedic operations, but in polytrauma patients undergoing orthopedic operations, it is not clear if and when TXA is safe or effective once outside the 3-h window of proven trauma efficacy...
March 10, 2024: Transfusion
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