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tympanic membrane

Michael C Topf, David W Hsu, Douglas R Adams, Tingting Zhan, Stanley Pelosi, Thomas O Willcox, Brian McGettigan, Kyle W Fisher
PURPOSE: To determine the rate of persistent tympanic membrane perforation after intratympanic steroid injection. To determine which comorbid conditions and risk factors are associated with prolonged time to perforation closure following intratympanic steroid injection. MATERIALS AND METHODS: Clinical data were gathered for patients who had undergone intratympanic steroid injection to treat sudden sensorineural hearing loss or Ménière's disease. Primary outcomes analysis included rate of persistent tympanic membrane perforation, defined as perforation at least 90days following last injection, and time to perforation healing...
September 28, 2016: American Journal of Otolaryngology
Meirav Sokolov, Ohad Hilly, David Ulanovski, Yotam Shkedy, Joseph Attias, Eyal Raveh
OBJECTIVES: Evaluate the intra- and postoperative effects of untreated otitis media with effusion (OME) in cochlear implant (CI) patients, and to assess the role of ventilation tube (VT) introduction before implantation. STUDY DESIGN: A retrospective chart review. SETTING: Tertiary referral center. PATIENTS: CI patients, aged 10 years or younger, implanted during 2009 to 2013. INTERVENTIONS: Cases were divided into three groups: 1) normal aerated middle ear before CI, 2) OME treated with VT, and 3) untreated OME...
September 30, 2016: Otology & Neurotology
Paul R Lambert, John Carey, Anthony A Mikulec, Carl LeBel
OBJECTIVE: To evaluate safety and efficacy of a single intratympanic injection of OTO-104, sustained-exposure dexamethasone, in patients with unilateral Ménière's disease. STUDY DESIGN: Randomized, double-blind, placebo-controlled, Phase 2b study over 5 months. SETTING: Fifty-two academic and community otolaryngology centers. PATIENTS: One hundred fifty four patients (77 per group) aged 18 to 85 years inclusive. INTERVENTION: Single intratympanic injection of OTO-104 (12 mg dexamethasone) or placebo...
September 30, 2016: Otology & Neurotology
Kaitlyn N Mula, Nicole M Cassler, Michael Dent, Max Gratrix
No abstract text is available yet for this article.
September 28, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Qin Shi, Dan Zhang, Zhen Huang, Peng Sun, Haiping Huang, Yunmei Zhang, Jianwu Dai, Jisheng Liu
Traumatic tympanic membrane (TM) perforation is very common in clinical practice. Several biomaterials have been reported to play a role in TM reparation, whereas their functional recovery is limited when used alone. Meanwhile, the administration of bio-factors could promote functional recovery, but rapid distribution and short half-time obstruct their application. In order to study the effect on of traumatic TM regeneration, we prepared collagen membrane (CM) integrated with collagen-binding basic fibroblast growth factor (CBD-bFGF) and implanted into the injury site of perforated TM in Sprague-Dawley (SD) rats...
October 12, 2016: Tissue Engineering. Part A
Noa Rozendorn, Michael Wolf, Arkadi Yakirevich, Yisgav Shapira, Eldar Carmel
BACKGROUND: Tympanic membrane perforation (TMP) may be caused by acute and chronic otitis media, trauma and iatrogenic reasons. The goal of myringoplasty is to achieve a dry, self-cleansing ear with intact TM while preserving hearing. Literature review of myringoplasty outcome demonstrates results with different success rates and affecting factors. OBJECTIVES: The aim of this study was to evaluate TMP closure (TMPC) rate and hearing improvement and to assess the effect of clinical and surgical parameters on residual and recurrent perforation...
November 2016: International Journal of Pediatric Otorhinolaryngology
Nuntigar Sonsuwan, Patcharin Watcharinyanon, Kittisak Sawanyawisuth
OBJECTIVES: Acute otitis media (AOM) is a common infectious disease in children. Data regarding the distribution of causative pathogens are not universal. Tympanic perforation due to AOM may occur in 5-30% of AOM patients. The causative pathogens for AOM with tympanic perforation are limited. METHODS: This was a prospective study conducted at the Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Thailand. All consecutive children diagnosed as having AOM with tympanic perforation were enrolled...
November 2016: International Journal of Pediatric Otorhinolaryngology
Chul Ho Jang, Eun Kyung Jung, Chung Man Sung, Seung Beom Kim, Young Yoon Kim, Jong Yuap Seong, Sung Hoon Kang, Yong Beom Cho
OBJECTIVE: Recently, minimally invasive transcanal myringotomy (MITM), which is a useful surgical technique for early stage congenital cholesteatoma (CC) in children, was introduced. The purpose of this study is to evaluate the short-term surgical results of MITM in pediatric early stage CC. MATERIALS AND METHODS: We retrospectively reviewed the charts of 24 patients who underwent MITM between January 2013 and October 2015. RESULTS: The patients' ages ranged from 1 to 16 years (mean, 2...
November 2016: International Journal of Pediatric Otorhinolaryngology
Wenchao Gao, Wenyu Liang, Kok Kiong Tan
To treat a worldwide common ear disease (OME), a device allowing fast grommet tube insertion has been designed in our earlier works (Gao et al., 2015 [1] and Liang et al., 2013 [2]). However, the instrument has to be manually placed as close as to the Tympanic Membrane before the insertion procedures. To realize a fully automated surgical process, the instrument shall be automatically manipulated to align to the axial direction of ear canal and proceed to complete the surgery. A vision-based servomechanism is proposed to solve the path planning problem...
October 5, 2016: ISA Transactions
Waqar Aslam, Lena Abou Nukta, Hassan Haidar, Ali Alsaadi, Hassanin Abdulkarim, Aisha Larem, Abdulsalam Alqahtani
Chemical closure of tympanic membrane perforation is a commonly practiced office-based otological procedure, which is labeled to be effective and safe. In this paper, we report a case of a young lady with disastrous complications following an attempt of chemical cauterization of her perforated tympanic membrane.
August 2016: Journal of International Advanced Otology
Dong Hee Lee, Jisun Kim, Eunhye Shin, Yulgyun Kim, Yesun Cho
OBJECTIVE: The aims of our study were to evaluate the outcome of office-based paper patch grafting in tympanic membrane (TM) perforation regardless of the disease duration or etiology and to compare the clinical factors influencing the successful closure of perforation between the success and failure groups of paper patch myringoplasty. MATERIALS AND METHODS: This is a retrospective study of 114 patients that underwent paper patch myringoplasty in an outpatient setting (success group, 83 cases; failure group, 31 cases)...
August 2016: Journal of International Advanced Otology
Taylan Gün, Osman Fatih Boztepe, Doğan Atan, Aykut İkincioğulları, Hüseyin Dere
OBJECTIVE: To compare the efficacy of three different myringoplasty techniques, namely hyaluronic acid fat graft myringoplasty (HAFGM), fat graft myringoplasty (FGM), and temporal fascia for the closure of different sizes and sites of tympanic membrane perforations. MATERIALS AND METHODS: We retrospectively analyzed the medical records of patients who had undergone a type 1 tympanoplasty operation at our clinic between May 2007 and February 2013. The patients were divided into three groups depending on the patient's choice of technique as follows: Fat Graft Myringoplasty (FGM) (Group I), Hyaluronic Acid Fat Graft Myringoplasty (HAFGM) (Group II), and Temporalis Fascia (TF) (Group III)...
August 2016: Journal of International Advanced Otology
Peymaneh Alizadeh Taheri, Shima Rostami, Manelie Sadeghi
Acute otitis externa (AOE) is an infection of the external auditory canal, the auricle, and the outer surface of the tympanic membrane. Although AOE is one of the most common otologic conditions encountered in pediatric population, it is known to primarily affect children older than 2 years. We report a case of AOE caused by Staphylococcus aureus in a 23-day-old neonate. A 23-day-old female infant presented to our neonatology clinic with irritability and discharge from the right ear. There were yellow otorrhea, mild erythema, and edema of right external ear canal...
2016: Case Reports in Infectious Diseases
Peter M Narins
Frogs and toads are capable of producing calls at potentially damaging levels that exceed 110 dB SPL at 50 cm. Most frog species have internally coupled ears (ICE) in which the tympanic membranes (TyMs) communicate directly via the large, permanently open Eustachian tubes, resulting in an inherently directional asymmetrical pressure-difference receiver. One active mechanism for auditory sensitivity reduction involves the pressure increase during vocalization that distends the TyM, reducing its low-frequency airborne sound sensitivity...
October 3, 2016: Biological Cybernetics
Bruce A Young
Many reptiles, and other vertebrates, have internally coupled ears in which a patent anatomical connection allows pressure waves generated by the displacement of one tympanic membrane to propagate (internally) through the head and, ultimately, influence the displacement of the contralateral tympanic membrane. The pattern of tympanic displacement caused by this internal coupling can give rise to novel sensory cues. The auditory mechanics of reptiles exhibit more anatomical variation than in any other vertebrate group...
October 3, 2016: Biological Cybernetics
S Torretta, P Marchisio, V Rinaldi, D Carioli, E Nazzari, L Pignataro
Hyaluronic acid (HA) is involved in modulating inflammatory airway processes and mucociliary clearance. Some studies have tested the effectiveness of the topical administration of HA in patients with upper airway diseases with positive preliminary results. A prospective, single-blind, 1:1 randomised controlled study was performed to assess the efficacy and safety of the daily topical administration of 9 mg of sodium hyaluronate in 3 mL of a 0.9 % sodium saline solution on the basis of endoscopic and clinical parameters in children with chronic adenoiditis associated with recurrent acute otitis media and otitis media with effusion; age- and gender-matched children receiving normal 0...
October 1, 2016: European Archives of Oto-rhino-laryngology
V V Wilmot, A Sharma
No abstract text is available yet for this article.
September 29, 2016: Clinical Otolaryngology
Thorin Jonsson, Fernando Montealegre-Z, Carl D Soulsbury, Kate A Robson Brown, Daniel Robert
The ear of the bush-cricket, Copiphora gorgonensis, consists of a system of paired eardrums (tympana) on each foreleg. In these insects, the ear is backed by an air-filled tube, the acoustic trachea (AT), which transfers sound from the prothoracic acoustic spiracle to the internal side of the eardrums. Both surfaces of the eardrums of this auditory system are exposed to sound, making it a directionally sensitive pressure difference receiver. A key feature of the AT is its capacity to reduce the velocity of sound propagation and alter the acoustic driving forces at the tympanum...
September 2016: Journal of the Royal Society, Interface
Bailey A Milne-Davies, Patrick J Antonelli, Nicklas C Orobello, Carolyn O Dirain
OBJECTIVE: To assess collagen and α-tubulin levels of mouse tympanic membrane fibroblasts treated with quinolone and aminoglycoside antibiotics at concentrations found in eardrops. STUDY DESIGN: Prospective controlled cell culture study. SETTING: Academic tertiary medical center. SUBJECTS: Mouse tympanic membrane fibroblasts. METHODS: In experiment 1, fibroblasts were treated with the following for 24 or 48 hours: phosphate-buffered saline (negative control), dilute hydrochloric acid (positive control), 0...
September 27, 2016: Otolaryngology—Head and Neck Surgery
N Principi, P Marchisio, C Rosazza, C S Sciarrabba, S Esposito
The principal aim of this review is to present the current knowledge regarding acute otitis media (AOM) with spontaneous tympanic membrane perforation (STMP) and to address the question of whether AOM with STMP is a disease with specific characteristics or a severe case of AOM. PubMed was used to search for all studies published over the past 15 years using the key words "acute otitis media" and "othorrea" or "spontaneous tympanic membrane perforation". More than 250 articles were found, but only those published in English and providing data on aspects related to perforation of infectious origin were considered...
September 27, 2016: European Journal of Clinical Microbiology & Infectious Diseases
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