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https://www.readbyqxmd.com/read/28798718/vestibular-modulation-of-sympathetic-nerve-activity-to-muscle-and-skin-in-humans
#1
REVIEW
Elie Hammam, Vaughan G Macefield
We review the existence of vestibulosympathetic reflexes in humans. While several methods to activate the human vestibular apparatus have been used, galvanic vestibular stimulation (GVS) is a means of selectively modulating vestibular afferent activity via electrodes over the mastoid processes, causing robust vestibular illusions of side-to-side movement. Sinusoidal GVS (sGVS) causes partial entrainment of sympathetic outflow to muscle and skin. Modulation of muscle sympathetic nerve activity (MSNA) from vestibular inputs competes with baroreceptor inputs, with stronger temporal coupling to the vestibular stimulus being observed at frequencies remote from the cardiac frequency; "super entrainment" was observed in some individuals...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28796081/the-seasonal-variation-of-benign-paroxysmal-positional-vertigo
#2
Sheneen Meghji, Declan Murphy, Ian Nunney, John S Phillips
OBJECTIVE: Benign paroxysmal positional vertigo (BPPV) is characterized by recurrent episodes of positional vertigo due to dislodged otoconia debris within the semicircular canals. Many studies have proposed a correlation between Vitamin-D deficiency and recurrent BPPV. In the UK, serum Vitamin-D falls during the winter, reaching its lowest level in May and it is highest level in September. We hypothesize that if there is a relationship between BPPV and Vitamin-D levels, one would expect to see a seasonal variation in the incidence of BPPV among UK residents...
August 8, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28791148/questioning-hagfish-affinities-of-the-enigmatic-devonian-vertebrate-palaeospondylus
#3
Zerina Johanson, Moya Smith, Sophie Sanchez, Tim Senden, Kate Trinajstic, Cathrin Pfaff
Palaeospondylus gunni Traquair, 1890 is an enigmatic Devonian vertebrate whose taxonomic affinities have been debated since it was first described. Most recently, Palaeospondylus has been identified as a stem-group hagfish (Myxinoidea). However, one character questioning this assignment is the presence of three semicircular canals in the otic region of the cartilaginous skull, a feature of jawed vertebrates. Additionally, new tomographic data reveal that the following characters of crown-group gnathostomes (chondrichthyans + osteichthyans) are present in Palaeospondylus: a longer telencephalic region of the braincase, separation of otic and occipital regions by the otico-occipital fissure, and vertebral centra...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28777229/the-modified-rambo-transcanal-approach-for-cochlear-implantation-in-charge-syndrome
#4
Cameron C Wick, Amy M Moore, Daniel E Killeen, Brandon Isaacson
OBJECTIVE: CHARGE syndrome is associated with a variety of temporal bone anomalies and deafness. The lack of surgical landmarks and facial nerve irregularities make cochlear implantation in this population a challenging endeavor. This study aims to describe a safe and efficacious transcanal approach for cochlear implantation that obviates the need to perform a mastoidectomy and facial recess. PATIENTS: Three children with profound hearing loss secondary to CHARGE syndrome...
August 2, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28776670/archosauriform-endocranial-morphology-and-osteological-evidence-for-semiaquatic-sensory-adaptations-in-phytosaurs
#5
Emily J Lessner, Michelle R Stocker
The examination of endocranial data of archosauriforms has led to advances on the evolution of body size, nerve pathways, and sensory abilities. However, much of that research has focused on bird-line archosaurs, resulting in a skewed view of Archosauria. Phytosauria, a hypothesized sister taxon to or early-branching member of Archosauria, provides a potential outgroup condition. Most previous phytosaur endocranial studies were executed without the use of modern technology and focused on derived members of Phytosauria...
August 4, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28775060/measurement-for-detection-of-incomplete-partition-type-ii-anomalies-on-mr-imaging
#6
K L Reinshagen, H D Curtin, A M Quesnel, A F Juliano
BACKGROUND AND PURPOSE: Incomplete partition type II of the cochlea, commonly coexisting with an enlarged vestibular aqueduct, can be a challenging diagnosis on MR imaging due to the presence of a dysplastic spiral lamina-basilar membrane neural complex, which can resemble the normal interscalar septum. The purpose of this study was to determine a reproducible, quantitative cochlear measurement to assess incomplete partition type II anomalies in patients with enlarged vestibular aqueducts using normal-hearing ears as a control population...
August 3, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28767521/disabling-central-paroxysmal-positioning-upbeat-nystagmus-and-vertigo-associated-with-the-presence-of-anti-glutamic-acid-decarboxylase-antibodies
#7
Ana I Martins, João N Carvalho, Ana M Amorim, Argemiro Geraldo, Eric Eggenberger, João Lemos
An immune attack by anti-glutamic acid decarboxylase (GAD) antibodies is believed to cause a deficiency in gamma-aminobutyric acid-mediated neurotransmission in the cerebellum. This, in turn, leads to several eye movement disorders, including spontaneous downbeat (DBN) and periodic alternating nystagmus. We describe a 68-year-old diabetic woman with disabling paroxysmal positioning upbeat nystagmus (UBN) exclusively in the supine position, associated with asymptomatic spontaneous DBN, alternating skew deviation and hyperactive vestibulo-ocular reflex responses on head impulse testing, in whom high titers of anti-GAD antibodies were detected...
August 1, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28741403/comparative-study-between-the-caloric-vestibular-and-the-video-head-impulse-tests-in-unilateral-meni%C3%A3-re-s-disease
#8
Jonathan Andrés Cordero-Yanza, Edna Verónica Arrieta Vázquez, Juan Carlos Hernaiz Leonardo, Jimena Mancera Sánchez, Mario Sabas Hernández Palestina, Nicolás Pérez-Fernández
OBJECTIVE: Compare the caloric vestibular test (CVT) and the video head impulse test (vHIT) in the evaluation of Meniere's disease (MD) and to analyze their diagnostic accuracy. MATERIALS AND METHODS: Retrospective review of CVT and vHIT performed in MD patients at a tertiary care referral center in Spain. RESULTS: A total of 88 patients were reviewed. The CVT was abnormal in 67% (n = 59) of patients, while the vHIT was abnormal in 66% (n = 58) of them...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28725982/analysis-of-risk-factors-influencing-the-outcome-of-the-epley-maneuver
#9
E Domínguez-Durán, E Domènech-Vadillo, M G Álvarez-Morujo de Sande, R González-Aguado, G Guerra-Jiménez, Á Ramos-Macías, C Morales-Angulo, A J Martín-Mateos, E Figuerola-Massana, H Galera-Ruiz
Benign paroxysmal positional vertigo (BPPV) is the most frequent type of vertigo. The treatment of canalithiasis of the posterior semicircular canal consists in performing a particle-repositioning maneuver, such as the Epley maneuver (EM). However, the EM is not effective in all cases. The objective of this study is to identify risk factors, which predict the EM failure, among the clinical variables recorded in anamnesis and patient examination. This is an observational prospective multicentric study. All patients presenting with BPPV were recruited and applied the EM and appointed for a follow-up visit 7 days later...
July 19, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28725523/a-method-of-locating-the-dehiscence-during-middle-fossa-approach-for-superior-semicircular-canal-dehiscence-surgery
#10
Joel S Beckett, Lawrance K Chung, Carlito Lagman, Brittany L Voth, Cheng Hao Jacky Chen, Bilwaj Gaonkar, Quinton Gopen, Isaac Yang
Objectives  Superior semicircular canal dehiscence (SSCD) results from a defect in the middle cranial fossa floor. One challenge during SSCD repair is the lack of a consistent landmark. This study proposes a reference point above the external auditory canal at the level of the zygoma as the inferior craniectomy edge during surgery. Design  This is a retrospective review of patients with SSCD. Setting/Participants  A total of 72 cases of SSCD in 60 patients were repaired via a middle fossa approach at a single institution...
August 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28723604/possible-joint-involvement-of-the-cochlea-and-semicircular-canals-in-the-perception-of-low-frequency-tinnitus-also-called-the-hum-or-taos-hum
#11
Franz Gunter Frosch
INTRODUCTION: "The hum" or "Taos hum" are common terms of a tinnitus with three remarkable features. OBJECTIVE: A possible common background is reevaluated for the three features of the hum: being sensitive on sound, head rotation, and long-distance air travel. MATERIALS AND METHODS: Questionnaires that were originally developed by Frosch were recalculated concerning the question of hum interactions with sounds. The question was split into the two affirmative answers a) "masking", which corresponds to the overrule of the hum by a sound, and b) "beats", which correspond to a nonlinear interaction with the hum as a Van der Pol-like oscillator...
June 1, 2017: International Tinnitus Journal
https://www.readbyqxmd.com/read/28713423/discovering-the-unexpected-with-the-utilization-of-ngs-in-diagnostics-of-non-syndromic-hearing-loss-disorders-the-family-case-of-ildr1-dependent-hearing-loss-disorder
#12
Jernej Kovač, Gašper Klančar, Katarina Trebušak Podkrajšek, Saba Battelino
Sensorineural hearing loss (SNHL) is a heterogeneous family of hearing disabilities with congenital (including genetic) as well as acquired etiology. Congenital SNHL of genetic etiology is further sub-divided into autosomal dominant, autosomal recessive and X-linked SNHL. More than 60 genes are involved in the etiology of autosomal recessive non-syndromic hearing loss (ARNSHL) commonly manifesting as heterogeneous pre-lingual profound to severe non-progressive clinical phenotype. ILDR1-dependent ARNSHL (DFNB42, OMIM: # 609646) is a very rare sub-type of hearing disability, with unknown prevalence, caused by function-damaging genetic variants in ILDR1 gene reported in families of Middle-Eastern origin...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/28705814/head-and-neck-mri-findings-in-charge-syndrome
#13
M J Hoch, S H Patel, D Jethanamest, W Win, G M Fatterpekar, J T Roland, M Hagiwara
Coloboma of the eye, Heart defects, Atresia of the choanae, Retardation of growth and/or development, Genital and/or urinary abnormalities, and Ear abnormalities and deafness (CHARGE) syndrome is a disorder with multiple congenital anomalies seen on imaging. A retrospective review of 10 patients with CHARGE syndrome who underwent MR imaging of the brain as part of a preoperative evaluation for cochlear implantation was conducted. Structural abnormalities of the entire MR imaging of the head were evaluated, including the auditory system, olfactory system, face, skull base, and central nervous system...
July 13, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28704895/comparisons-in-outcome-and-subject-comfort-between-rotation-chair-systems
#14
Bong Jik Kim, Yu-Kyung Won, Jaihwan Hyun, Woo-Sung Na, Jae Yun Jung, Myung-Whan Suh
BACKGROUND AND OBJECTIVES: A rotation chair test has been used to evaluate the function of the horizontal semicircular canals. Currently, two chair systems according to the presence of cylindrical darkroom are used in a clinic setting. However, it has not been thoroughly investigated whether one system is superior to the other system or not. In this study, we aimed to compare test outcomes and subject convenience between two systems. SUBJECTS AND METHODS: Twenty subjects with no history of otologic disease were enrolled...
July 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28686379/-anterior-semicircular-canal-benign-paroxysmal-positional-vertigo
#15
Stephen Jacques Alzuphar, Raphaël Maire
Anterior semicircular canal Benign Paroxysmal Positional Vertigo (antBPPV) is the rarest form of semicircular canalolithiasis, corresponding to about 1-2 % of the BPPV. The diagnosis is obtained by either the Dix-Hallpike maneuver or the straight head hanging positioning maneuver, which provoke a characteristic positional down-beating nystagmus. This vertical nystagmus can be associated with a torsional component that helps in localizing the affected side. The differential diagnosis of antBPPV includes the various central lesions that produce vertical down beating nystagmus (posterior fossa)...
October 5, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28685312/affected-ear-up-120%C3%A2-maneuver-for-treatment-of-lateral-semicircular-canal-benign-paroxysmal-positional-vertigo
#16
Hiroaki Ichijo
Although several researchers have tried various canalith repositioning procedures for lateral canalolithiasis, a standard treatment has not been established. We adopt 120° rotation, which is anatomically appropriate because the principle of cure may be the fixing of pathological debris to the dark cells of the utricle. The aims of this study were to clarify the efficacy rate of the affected-ear-up 120° maneuver and to elucidate the appearance rate of lying-down nystagmus in patients with lateral canalolithiasis...
July 6, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28684743/inner-ear-ossification-and-mineralization-kinetics-in-human-embryonic-development-microtomographic-and-histomorphological-study
#17
Céline Richard, Guillaume Courbon, Norbert Laroche, Jean Michel Prades, Laurence Vico, Luc Malaval
Little is known about middle and inner ear development during the second and third parts of human fetal life. Using ultra-high resolution Microcomputed Tomography coupled with bone histology, we performed the first quantitative middle and inner ear ossification/mineralization evaluation of fetuses between 17 and 39 weeks of gestational age. We show distinct ossification paces between ossicles, with a belated development of the stapes. A complete cochlear bony covering is observed within the time-frame of the onset of hearing, whereas distinct time courses of ossification for semicircular canal envelopes are observed in relation to the start of vestibular functions...
July 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28680491/relation-between-ossicular-erosion-and-destruction-of-facial-and-lateral-semicircular-canals-in-chronic-otitis-media
#18
Suphi Bulğurcu, İlker Burak Arslan, Bünyamin Dikilitaş, İbrahim Çukurova
Introduction  Chronic otitis media can cause multiple middle ear pathogeneses. The surgeon should be aware of relation between ossicular chain erosion and other destructions because of the possibility of complications. Objective  This study aimed to investigate the rates of ossicular erosion in cases of patients with and without facial nerve canal destruction, who had undergone mastoidectomy due to chronic otitis media with or without cholesteatoma. Methods  We retrospectively analyzed three hundred twenty-seven patients who had undergone tympanomastoidectomy between April 2008 and February 2014...
July 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28668955/influence-of-sex-and-age-on-posterior-semicircular-canal-thickness
#19
Jaime Whyte, M Teresa Tejedor, Luis V Monteagudo, Ana Whyte, Ana I Cisneros, Rafael Crovetto, Jesus J Fraile, Miguel A Crovetto
OBJECTIVE: The aim of this study is to determine whether sex and age influence posterior semicircular canal (PSC) thickness. METHODS: This observational study was conducted in 3 tertiary hospitals. The minimal distance between the PSC and the posterior cranial fossa (PSC thickness) was estimated by thin-section multidetector row computed axial tomography (CAT) scan of the temporal bones. Nonselected consecutive patients of all ages (607 temporal bones) were considered...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28667933/contrasting-results-of-tests-of-peripheral-vestibular-function-in-patients-with-bilateral-large-vestibular-aqueduct-syndrome
#20
Yu-Juan Zhou, Yong-Zhen Wu, Ning Cong, Jing Yu, Jun Gu, Jing Wang, Fang-Lu Chi
OBJECTIVE: To analyze and summarize the effect of bilateral large vestibular aqueducts in peripheral vestibular organ function. METHODS: Eighteen patients with bilateral large vestibular aqueduct syndrome (LVAS; Study Group) and 18 healthy volunteers (Control Group) were investigated using audiometry, caloric test, sensory organization test (SOT), and vestibular-evoked myogenic potential (VEMP) tests. RESULTS: All 18 patients (36 ears) exhibited sensorineural hearing loss...
June 7, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
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