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https://www.readbyqxmd.com/read/28228581/spaceflight-induced-synaptic-modifications-within-hair-cells-of-the-mammalian-utricle
#1
David R Sultemeier, Kristel R Choy, Felix E Schweizer, Larry F Hoffman
Exposure to the microgravity conditions of spaceflight alleviates the load normally imposed by the Earth's gravitational field upon the inner ear utricular epithelia. Previous ultrastructural investigations showed that spaceflight induced an increase in synapse density within hair cells of the rat utricle. However, the utricle exhibits broad physiologic heterogeneity across different epithelial regions, and it is unknown whether capabilities for synaptic plasticity generalize to hair cells across its topography...
February 22, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28224454/effects-of-sustained-otolith-only-stimulation-on-post-rotational-nystagmus
#2
Aasef G Shaikh, David Solomon
Constant velocity rotations in darkness evoke vestibulo-ocular reflex in form of pre- and post-rotational nystagmus under cerebellar supervision. Reorientation of the head with respect to gravity, stimulating otolith and semicircular canal, during post-rotational phase rapidly suppresses the post-rotational nystagmus. We asked if pure otolith stimulation without semicircular canal signal is sufficient for the suppression of post-rotational nystagmus. The experimental paradigm comprised of on-axis rotations in the horizontal plane when the subject was sitting upright, followed by a novel stimulus that combined off-axis centrifugation in the horizontal plane with amplitude matched, yet out-of-phase, on-axis horizontal rotation-double centrifugation...
February 21, 2017: Cerebellum
https://www.readbyqxmd.com/read/28219173/-violation-with-horizontal-semicircular-canal-of-the-middle-ear-adenoma-a-case-report
#3
M C Zhu, G J Tan, Y N Jiao, F Yu, M M Ai, X R Gong
No abstract text is available yet for this article.
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28212886/primary-ameloblastoma-of-the-temporal-bone
#4
Andro Košec, Jakov Ajduk, Mihael Ries, Robert Trotić
Ameloblastoma is a locally aggressive tumor derived from odontogenic epithelium. Although benign, its clinical behavior can often exhibit malignant characteristics. It is marked by slow and persistent growth with infiltration of adjacent tissues. Almost 70% occur in the mandible in patients older than 30 years. Recurrence of ameloblastoma from inadequate treatment is frequent. Because of its slow growth, recurrences can present decades after primary surgery. A primary ameloblastoma in an area outside the mandibular, maxillary, and infratemporal fossa regions has not been described in detail to date, with only 1 possible case mentioned in the literature...
January 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28185320/orientation-of-the-lateral-semicircular-canal-in-xenarthra-and-its-links-with-head-posture-and-phylogeny
#5
Florence Coutier, Lionel Hautier, Raphaël Cornette, Eli Amson, Guillaume Billet
The orientation of the semicircular canals of the inner ear in the skull of vertebrates is one of the determinants of the capacity of this system to detect a given rotational movement of the head. Past functional studies on the spatial orientation of the semicircular canals essentially focused on the lateral semicircular canal (LSC), which is supposedly held close to horizontal during rest and/or alert behaviors. However, they generally investigated this feature in only a few and distantly related taxa. Based on 3D-models reconstructed from µCT-scans of skulls, we examined the diversity of orientations of the LSC within one of the four major clades of placental mammals, that is, the superorder Xenarthra, with a data set that includes almost all extant genera and two extinct taxa...
February 10, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28177336/nystagmus-intensity-and-direction-in-bow-and-lean-test-an-aid-to-diagnosis-of-lateral-semicircular-canal-benign-paroxysmal-positional-vertigo
#6
V Marcelli
The objective was to evaluate nystagmus intensity and direction (NID) during bow and lean test (BLT) in subjects suffering from idiopathic lateral semicircular canal benign paroxysmal positional vertigo (LSC-BPPV), in order to differentiate between the geotropic and the apogeotropic form and to determine the affected ear before using classic diagnostic procedures. The BLT was performed in 32 subjects affected by LSC-BPPV. "Nystagmus intensity" evaluation allows distinguishing the geotropic variant from the apogeotropic one, while the "nystagmus direction" allows identification of the side...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28168899/correlation-of-objective-audiometric-and-caloric-function-in-m%C3%A3-ni%C3%A3-re-s-disease
#7
Kyle P McMullen, Chen Lin, Michael S Harris, Oliver F Adunka
Objective Ménière's disease affects the vestibular and audiologic systems; however, little is known about the relationship between audiometric and caloric function with increasing duration of disease. We employed a novel methodology to understand the longitudinal correlation between audiometric and caloric function in Ménière's patients. Study Design Case series with chart review. Setting Neuro-otologic tertiary care practice. Subjects and Methods Charts of 19 patients with unilateral Ménière's disease, as classified by the 1995 American Academy of Otolaryngology-Head and Neck Foundation criteria, were examined...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28168887/cervical-and-ocular-vemp-testing-in-diagnosing-superior-semicircular-canal-dehiscence
#8
Jacob B Hunter, Neil S Patel, Brendan P O'Connell, Matthew L Carlson, Neil T Shepard, Devin L McCaslin, George B Wanna
Objective To determine the sensitivity and specificity of ocular and cervical vestibular evoked myogenic potentials (VEMPs) in the diagnosis of superior semicircular canal dehiscence (SCD) and to describe the VEMP response characteristics that are most sensitive to SCD and compare the findings to previous reports. Study Design Case series with chart review. Setting Two tertiary neurotologic referral centers. Subjects and Methods Cervical and ocular VEMP peak-to-peak amplitudes and thresholds from 39 adult patients older than 18 years with surgically confirmed SCD were compared with 84 age-matched controls...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28159525/celsr1-coordinates-the-planar-polarity-of-vestibular-hair-cells-during-inner-ear-development
#9
Jeremy S Duncan, Michelle L Stoller, Andrew F Francl, Fadel Tissir, Danelle Devenport, Michael R Deans
Vestibular hair cells of the inner ear are specialized receptors that detect mechanical stimuli from gravity and motion via the deflection of a polarized bundle of stereocilia located on their apical cell surfaces. The orientation of stereociliary bundles is coordinated between neighboring cells by core PCP proteins including the large adhesive G-protein coupled receptor Celsr1. We show that mice lacking Celsr1 have vestibular behavioral phenotypes including circling. In addition, we show that Celsr1 is asymmetrically distributed at cell boundaries between hair cells and neighboring supporting cells in the developing vestibular and auditory sensory epithelia...
February 1, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28154359/impairments-of-inner-ears-caused-by-physical-environmental-stresses
#10
Nobutaka Ohgami, Reina Oshino, Hiromasa Ninomiya, Xiang Li, Masashi Kato
The inner ears contain the organ of Corti, vestibule and semicircular canal. The organ of Corti is crucial for hearing, while the vestibule and semicircular canal play important roles in maintaining balance. Exposure to noise at excessive levels is known to cause damages of the inner ears, resulting in noise-induced hearing loss. On the other hand, noise levels (dB) are used for the evaluation of health risks by exposure to noise, although noise consists of sound with broad frequencies (Hz). Thus, information about the frequency-dependent effect of noise on health is largely unknown...
2017: Nihon Eiseigaku Zasshi. Japanese Journal of Hygiene
https://www.readbyqxmd.com/read/28127679/motion-illusion-evidence-towards-human-vestibulo-thalamic-projections
#11
Aasef G Shaikh, Dominik Straumann, Antonella Palla
Contemporary studies speculated that cerebellar network responsible for motion perception projects to the cerebral cortex via vestibulo-thalamus. Here, we sought for the physiological properties of vestibulo-thalamic pathway responsible for the motion perception. Healthy subjects and the patient with focal vestibulo-thalamic lacunar stroke spun a hand-held rheostat to approximate the value of perceived angular velocity during whole-body passive earth-vertical axis rotations in yaw plane. Vestibulo-ocular reflex was simultaneously measured with high-resolution search coils (paradigm 1)...
January 27, 2017: Cerebellum
https://www.readbyqxmd.com/read/28117786/dissection-of-the-auditory-bulla-in-postnatal-mice-isolation-of-the-middle-ear-bones-and-histological-analysis
#12
Ayako Sakamoto, Yukiko Kuroda, Sho Kanzaki, Koichi Matsuo
In most mammals, auditory ossicles in the middle ear, including the malleus, incus and stapes, are the smallest bones. In mice, a bony structure called the auditory bulla houses the ossicles, whereas the auditory capsule encloses the inner ear, namely the cochlea and semicircular canals. Murine ossicles are essential for hearing and thus of great interest to researchers in the field of otolaryngology, but their metabolism, development, and evolution are highly relevant to other fields. Altered bone metabolism can affect hearing function in adult mice, and various gene-deficient mice show changes in morphogenesis of auditory ossicles in utero...
January 4, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28115052/-temporary-loss-of-vestibular-function-after-cochlear-implant-surgery
#13
Leise Elisabeth Hviid Korsager, Jesper Hvass Schmidt, Christian Faber, Jens Højberg Wanscher
Loss of vestibular function is a common side effect to cochlear implant (CI) surgery. We present a patient who experienced balance problems and showed a reduced vestibulo-ocular reflex (VOR) gain (0.47 ± 0.10) combined with saccades in the horizontal semicircular canals demonstrated by the video head impulse test the day after CI surgery. One month after the operation VOR gain was normal (0.95 ± 0.05) and neither balance problems nor saccades occurred. Our findings indicate that vestibular dysfunction after CI surgery can be reversible, and VOR gain can return to normal...
January 23, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28104012/-simultaneous-triple-semicircular-canal-plugging-and-cochlear-implantation-in-advanced-meniere-s-disease
#14
D G Zhang, L Xu, Y C Han, Y F Lyu, J F Luo, Y W Li, R J Wang, Z M Fan, H B Wang
Objective: To evaluate the feasibility of combining simultaneous triple semicircular canal plugging (TSCP) and cochlear implantation (CI) to treat vertigo and hearing loss in advanced Meniere's disease(MD) patients, so as to provide an alternative surgical procedure for treating this disorder. Methods: Data from seven patients, who were referred to our hospital and diagnosed with unilateral MD strictly meeting the criteria issued by Chinese Academy of Otolaryngology-Head and Neck Surgery Committee (2006), from Jan...
January 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28101918/plastic-temporal-bones
#15
LETTER
A M Pettigrew
No abstract text is available yet for this article.
January 18, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28087417/culture-media-based-selection-of-endothelial-cells-pericytes-and-perivascular-resident-macrophage-like-melanocytes-from-the-young-mouse-vestibular-system
#16
Jinhui Zhang, Songlin Chen, Jing Cai, Zhiqiang Hou, Xiaohan Wang, Allan Kachelmeier, Xiaorui Shi
The vestibular blood-labyrinth barrier (BLB) is comprised of perivascular-resident macrophage-like melanocytes (PVM/Ms) and pericytes (PCs), in addition to endothelial cells (ECs) and basement membrane (BM), and bears strong resemblance to the cochlear BLB in the stria vascularis. Over the past few decades, in vitro cell-based models have been widely used in blood-brain barrier (BBB) and blood-retina barrier (BRB) research, and have proved to be powerful tools for studying cell-cell interactions in their respective organs...
March 2017: Hearing Research
https://www.readbyqxmd.com/read/28063321/clinical-implication-of-cervical-vestibular-evoked-myogenic-potentials-in-benign-paroxysmal-positional-vertigo
#17
Mun Young Chang, Ji Ho Shin, Kyung Hyun Oh, Young Ho Hong, Seog-Kyun Mun
OBJECTIVES: To evaluate the value of cervical vestibular evoked myogenic potential (cVEMP) as a prognostic factor for benign paroxysmal positional vertigo (BPPV). METHODS: We reviewed 65 patients with BPPV who underwent cVEMP. Patients were divided into two groups according to resistance to the repositioning maneuver. Univariable and multivariable analyses were performed with age, gender, affected semicircular canal, affected side and cVEMP parameters to find the associated factors for resistance to the repositioning maneuver...
February 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28061922/respiratory-and-pulse-changes-due-to-vestibular-stimulations-in-a-motion-based-simulator
#18
Savas Ilbasmis, Safak Yildiz
INTRODUCTION: One of the mechanisms leading to spatial disorientation (SD) is overstimulation of the vestibular system by various aircraft maneuvers. The objective of this study was to observe respiratory rate and pulse changes during vestibular system stimulations with the help of two selected SD training profiles. METHODS: The respiration and pulse rates of 15 subjects were recorded in response to 2 sequential SD training profiles on a motion-based simulator. The session started with a motionless instruction period (IP), continued with a Coriolis profile (CP) which stimulated the semicircular canals, and ended with a Dark Takeoff profile (DP) which stimulated the otolith organs...
January 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28045785/cold-thermal-irrigation-decreases-the-ipsilateral-gain-of-the-vestibulo-ocular-reflex
#19
Laszlo T Tamás, Konrad P Weber, Christopher J Bockisch, Dominik Straumann, David M Lasker, Béla Büki, Alexander A Tarnutzer
OBJECTIVES: During head rotations, neuronal firing rates increase in ipsilateral and decrease in contralateral vestibular afferents. At low accelerations, this "push-pull mechanism" is linear. At high accelerations, however, the change of firing rates is nonlinear in that the ipsilateral increase of firing rate is larger than the contralateral decrease. This mechanism of stronger ipsilateral excitation than contralateral inhibition during high-acceleration head rotation, known as Ewald's second law, is implemented within the nonlinear pathways...
December 27, 2016: Ear and Hearing
https://www.readbyqxmd.com/read/28012532/management-of-surgical-difficulties-during-cochlear-implant-with-inner-ear-anomalies
#20
Ahmad M Aldhafeeri, Abdulrahman A Alsanosi
OBJECTIVE: To review the difficulties that can occur during cochlear implant surgery in patients with inner ear abnormalities and the management thereof. METHODS: A retrospective chart review of 316 patients who received cochlear implants was conducted. The data collected included the types of inner ear anomalies, intraoperative findings, and the clinical management strategies. A review of the literature was also performed. RESULTS: A total of 24 patients with inner ear malformations who underwent 28 total cochlear implant procedures were identified...
January 2017: International Journal of Pediatric Otorhinolaryngology
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