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Magnifying endoscopy

Masaya Iwamuro, Katsuyoshi Takata, Seiji Kawano, Nobuharu Fujii, Yoshiro Kawahara, Tadashi Yoshino, Hiroyuki Okada
A 70-year-old woman presented with follicular lymphoma involving the stomach, duodenum, jejunum, bone, and lymph nodes. Esophagogastroduodenoscopy revealed multiple depressed lesions in the stomach. Examination with magnifying endoscopy showed branched abnormal vessels along with gastric pits, which were irregularly shaped but were preserved. The second case was a 45-year-old man diagnosed with stage II1 follicular lymphoma with duodenal, ileal, and colorectal involvement, as well as lymphadenopathy of the mesenteric lymph nodes...
2016: Case Reports in Gastrointestinal Medicine
Takahiko Ito, Shuko Morita, Naoto Shimeno, Keiichiro Uehara, Yukihiro Imai, Tetsuro Inokuma
Squamous cell carcinoma (SCC) of the anal canal is seldom diagnosed at an early stage. Chemoradiation therapy is a standard in Europe and the United States, though in squamous cell carcinoma there is no evidence-based therapy. In Japan, endoscopic submucosal dissection (ESD) is the standard minimally invasive treatment for early stage cancer of the digestive tract, including the colorectum. Therefore, if the lesion is diagnosed at an early stage, ESD may be selected for anal canal lesions. We experienced two cases of early stage anal canal cancer in which the diagnosis and the extent of the lesions were confirmed using magnifying endoscopy with narrow-band imaging (NBI), as well as performing ESD...
October 13, 2016: Clinical Journal of Gastroenterology
Kazuki Sumiyama
Methodology for the diagnosis and staging of early gastric cancer (EGC) has improved in Japan since the development of the gastro-camera and determination of a definition of EGC. Imaging technology has been steadily evolving in the endoscopy field. Improvements in the resolution of standard endoscopy images used in screening and surveillance provide greater opportunities to find gastric cancer earlier. Image enhancement endoscopy (IEE), such as narrow band imaging (NBI), highlights mucosal structures and vascularity...
October 12, 2016: Gastric Cancer
Takashi Murakami, Naoto Sakamoto, Hideaki Ritsuno, Tomoyoshi Shibuya, Taro Osada, Hiroyuki Mitomi, Takashi Yao, Sumio Watanabe
BACKGROUND AND AIMS: Sessile serrated adenoma/polyp (SSA/P) is a colorectal polyp that possesses malignant potential. However, the dysplastic components within a SSA/P can be difficult to detect. This study aimed to clarify the endoscopic characteristics of SSA/P with advanced histology. METHODS: We examined 462 endoscopically or surgically resected lesions that were pathologically diagnosed as SSA/P, including 414 without and 41 with cytological dysplasia, and 7 with invasive carcinoma...
September 20, 2016: Gastrointestinal Endoscopy
Yoshiya Kobayashi, Yoshinori Komazawa, Makoto Nagaoka, Yoshiko Takahashi, Mika Yuki, Toshihiro Shizuki, Toru Nabika
A 49-year-old woman underwent an esophagogastroduodenoscopy as part of a health check at our hospital. Endoscopic observation revealed a flat elevated lesion 6 mm in diameter in the gastric antrum (Paris Classification type IIa). Magnifying endoscopy using narrow-band imaging showed a slightly irregular micro-surface pattern with round and oval pits, as well as a regular micro-vascular pattern without a demarcation line. Atrophy and intestinal metaplasia were not recognized in the background gastric mucosa...
September 2016: Endoscopy International Open
Takashi Kumamoto, Kazuhiro Sentani, Shiro Oka, Shinji Tanaka, Wataru Yasui
BACKGROUND AND STUDY AIMS: Magnifying narrow-band imaging (NBI) endoscopy enables the diagnosis of minute esophageal neoplasia. We aimed to evaluate clinicopathological diagnosis of minute esophageal neoplasia by using magnifying NBI endoscopy and biopsy. PATIENTS AND METHODS: In total, 309 patients (127 men and 182 women) with minute esophageal lesions of intrapapillary capillary loop (IPCL) type IV were enrolled. Of these patients, 249 underwent biopsy for histologic diagnosis and also for treatment...
September 2016: Endoscopy International Open
Yuji Eso, Yoshitaka Nishikawa, Atsushi Takai
Colorectal follicular lymphomas, primary or secondary, are rare. Magnifying endoscopy with narrow-band imaging is useful in the diagnosis of colorectal follicular lymphoma. In addition, immunohistochemistry is essential in differentiating follicular lymphoma cells from lymphoid follicle hyperplasia based on the presence of Bcl-2 expression. We herein report a rare case of follicular lymphoma of the caecum, presenting as a small polyp that was resected endoscopically.
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
Neel Sharma
Sano and colleagues have successfully highlighted the current advances in the utilisation of NBI magnifying endoscopic classification of colorectal tumours. As a gastroenterologist and educationalist I wanted to promote discussion regarding how best to educate learners in this regard. Evidence highlights time and again that the rate of competency gain among learners in any form of diagnostic endoscopy varies with little understanding as to why this may be the case. This article is protected by copyright. All rights reserved...
September 8, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Nei Soma
Evaluating the prevalence of gastritis by endoscopy is useful for estimating the risk of gastric cancer. Moreover, understanding the endoscopic appearances of gastritis is important for diagnosing gastric cancer due to the superficial mucosal lesions that mimic gastritis (gastritis-like lesions) are very difficult to detect even with optimum preparation and the best technique, and in such cases the tissue biopsy is often not very accurate for the diagnosis of gastric epithelial neoplasia. Magnifying endoscopy is a highly accurate technique for the detection of EGC (early gastric cancer)...
August 31, 2016: Journal of Digestive Diseases
Noriya Uedo, Kenshi Yao
Although dye-based and image-enhanced endoscopic techniques have revolutionized endoscopic diagnosis, conventional white light endoscopy still plays an important role in the diagnosis of early gastric cancer (EGC) during routine endoscopy. Chromoendoscopy reveals morphological characteristics of the mucosal lesions by enhancing mucosal contrast, while narrow-band imaging (NBI) facilitates detailed evaluation of the vascular architecture and surface features. Positive diagnostic findings of EGC on white light imaging and indigo carmine chromoendoscopy are a sharply demarcated lesion and irregularity in surface morphology or color...
2016: Advances in Experimental Medicine and Biology
Yusuke Horiuchi, Junko Fujisaki, Noriko Yamamoto, Tomoki Shimizu, Masami Omae, Akiyoshi Ishiyama, Toshiyuki Yoshio, Toshiaki Hirasawa, Yorimasa Yamamoto, Tomohiro Tsuchida, Masahiro Igarashi, Hiroshi Takahashi
BACKGROUND AND AIM: The usefulness of magnifying endoscopy with narrow-band imaging (ME-NBI) in undifferentiated-type early gastric cancers (UD-type EGCs) is unclear. This study investigated the accuracy of ME-NBI in the diagnostic demarcation. METHODS: Among UD-type EGCs that were initially surgically resected between June 2011 and August 2014 in this hospital, 74 lesions were studied that were preoperatively diagnosed with white-light imaging (WLI) or endoscopic ultrasonography as lesions for which endoscopic treatment was not indicated and found to be early gastric cancers by postoperative pathology...
August 29, 2016: Surgical Endoscopy
Youichi Miyaoka, Aya Fujiwara, Satoshi Kotani, Kosuke Tsukano, Sayaka Ogawa, Satoshi Yamanouchi, Ryusaku Kusunoki, Hirofumi Fujishiro, Naruaki Kohge, Tomohiko Yamamoto, Yuji Amano
We present a case of invasive micropapillary carcinoma (IMPC) of the colon treated by endoscopic resection following magnifying endoscopy. A 47-year-old woman visited our hospital for follow-up of a positive fecal occult blood test. Colonoscopy revealed a semi-pedunculated reddish polyp, the surface of which showed gentle irregularity, and mild tension in the sigmoid colon. Magnifying colonoscopy with narrow band imaging revealed an irregular surface pattern with heterogeneity in vascular diameter and distribution...
July 2016: Endoscopy International Open
Itsuko Asada-Hirayama, Shinya Kodashima, Yoshiki Sakaguchi, Satoshi Ono, Keiko Niimi, Satoshi Mochizuki, Yosuke Tsuji, Chihiro Minatsuki, Satoki Shichijo, Keisuke Matsuzaka, Tetsuo Ushiku, Masashi Fukayama, Nobutake Yamamichi, Mitsuhiro Fujishiro, Kazuhiko Koike
BACKGROUND AND STUDY AIMS: Although magnifying endoscopy with narrow-band imaging (ME-NBI) is reported to be useful for delineating the horizontal extent of early gastric cancers (EGCs), there are few reports which have objectively demonstrated the superiority of ME-NBI over chromoendoscopy with indigo carmine for this purpose. We conducted an exploratory comparison of the diagnostic accuracy of both modalities for the delineation of EGCs using prospectively collected data, and clarified the clinicopathological features related to inaccurate evaluation of the horizontal extent of EGCs...
June 2016: Endoscopy International Open
Masaaki Kobayashi, Satoru Hashimoto, Ken-Ichi Mizuno, Manabu Takeuchi, Yuichi Sato, Gen Watanabe, Yoichi Ajioka, Motoi Azumi, Kouhei Akazawa, Shuji Terai
BACKGROUND AND STUDY AIMS: We previously reported that narrow-band imaging with magnifying endoscopy (NBI-ME) revealed a unique "gastritis-like" appearance in approximately 40 % of early gastric cancers after Helicobacter pylori eradication. Because rates of gastric cancer are increasing in patients with non-persistent infection of H. pylori, we aimed to clarify contribution factors to obscure tumors after therapeutic or spontaneous eradication. PATIENTS AND METHODS: NBI-ME findings were examined retrospectively in 194 differentiated-type adenocarcinomas from H...
June 2016: Endoscopy International Open
Masashi Kawamura, Hiroshi Naganuma, Rie Shibuya, Tatsuya Kikuchi, Yoshitaka Sakai, Futoshi Nagasaki, Eiki Nomura, Noriaki Suzuki, Eri Saito
BACKGROUND AND STUDY AIMS: Intramucosal vascular density differs between differentiated and undifferentiated type gastric carcinomas. This study aimed to evaluate the microvascular density characteristics of these two types of carcinoma using magnifying endoscopy with narrow-band imaging (ME-NBI). PATIENTS AND METHODS: In total, 42 differentiated and 10 undifferentiated types were evaluated. The microvessels observed using ME-NBI were extracted from stored still images and the microvascular density in the two carcinoma types was analyzed...
August 2016: Endoscopy International Open
Taweesak Tongtawee, Theeraya Bartpho, Soraya Kaewpitoon, Natthawut Kaewpitoon, Chavaboon Dechsukhum, Wilairat Leeanansaksiri, Ryan A Loyd, Likit Matrakool, Sukij Panpimanmas
BACKGROUND: Helicobacter pylori is now recognized as a causative factor of chronic gastritis, gastroduodenal ulcers, gastric cancer and mucosaassociated lymphatic tissue lymphoma. Tolllike receptors are important bacterial receptors in gastric epithelial cell signaling transduction and play critical roles in gastric carcinogenesis. MATERIALS AND METHODS: A total of 400 patients undergoing esophagogastroduodenoscopy for investigation of chronic abdominal pain were genotyped for singlenucleotide polymorphisms (SNPs) in TLR1 (rs4833095) using TagMan SNPs genotyping assay by realtime PCR hybridization...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
Yuichi Mori, Shin-Ei Kudo, Philip Wai Yan Chiu, Rajvinder Singh, Masashi Misawa, Kunihiko Wakamura, Toyoki Kudo, Takemasa Hayashi, Atsushi Katagiri, Hideyuki Miyachi, Fumio Ishida, Yasuharu Maeda, Haruhiro Inoue, Yukitaka Nimura, Masahiro Oda, Kensaku Mori
Background and study aims: Optical diagnosis of colorectal polyps is expected to improve the cost-effectiveness of colonoscopy, but achieving a high accuracy is difficult for trainees. Computer-aided diagnosis (CAD) is therefore receiving attention as an attractive tool. This study aimed to validate the efficacy of the latest CAD model for endocytoscopy (380-fold ultra-magnifying endoscopy). Patients and methods: This international web-based trial was conducted between August and November 2015. A web-based test comprising one white-light and one endocytoscopic image of 205 small colorectal polyps (≤ 10 mm) from 123 patients was undertaken by both CAD and by endoscopists (three experts and ten non-experts from three countries)...
August 5, 2016: Endoscopy
Ming-Yan Cai, Yuan Huang, Jia-Xin Xu, Ping-Hong Zhou
No abstract text is available yet for this article.
July 19, 2016: Gastrointestinal Endoscopy
Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Biopsies are necessary for the management of duodenal tumors. However, the most suitable targets for biopsy are not known. An 82-year-old woman who regularly visited our hospital for rheumatoid arthritis underwent abdominal ultrasonography. This screening revealed a dilated pancreatic duct. Magnetic resonance cholangiopancreatography was performed, and dilatation of the pancreatic duct was confirmed. The patient underwent duodenoscopy to investigate the possibility of obstruction of the papilla of Vater. The examination revealed an elevated lesion around the papilla of Vater...
January 2016: Case Reports in Gastroenterology
Osamu Dohi, Nobuaki Yagi, Atsushi Majima, Yusuke Horii, Tomoko Kitaichi, Yuriko Onozawa, Kentaro Suzuki, Akira Tomie, Reiko Kimura-Tsuchiya, Toshifumi Tsuji, Nobuhisa Yamada, Nobukatsu Bito, Tetsuya Okayama, Naohisa Yoshida, Kazuhiro Kamada, Kazuhiro Katada, Kazuhiko Uchiyama, Takeshi Ishikawa, Tomohisa Takagi, Osamu Handa, Hideyuki Konishi, Yuji Naito, Akio Yanagisawa, Yoshito Itoh
BACKGROUND: Blue laser imaging (BLI) is a new image-enhanced endoscopy technique that utilizes a laser light source developed for narrow-band light observation. The aim of this study was to evaluate the usefulness of BLI for the diagnosis of early gastric cancer. METHODS: This single center prospective study analyzed 530 patients. The patients were examined with both conventional endoscopy with white-light imaging (C-WLI) and magnifying endoscopy with BLI (M-BLI) at Kyoto Prefectural University of Medicine between November 2012 and March 2015...
June 13, 2016: Gastric Cancer
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