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https://www.readbyqxmd.com/read/28646703/comparison-of-type-2-diabetes-prevalence-in-chinese-migrants-vs-caucasians-and-new-perspectives-for-screening-of-cerebrovascular-disease-in-chinese-a-proof-of-concept-study
#1
Pietro A Modesti, Sergio Castellani, Maria Calabrese, Danilo Malandrino, Dong Zhao
AIMS: Type 2 diabetes (T2DM) is a recognized risk factor for intracranial stenosis (ICS) in China where ischemic stroke is a health priority. In Europe little information is available on T2DM prevalence among Chinese minority groups and vascular screening is commonly limited to extracranial vessels. Feasibility of community-based T2DM screening, differences in T2DM prevalence between Chinese migrants and Italians, and prevalence of ICS among Chinese patients with newly diagnosed T2DM were investigated...
June 13, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28646694/elimination-of-signals-tilting-caused-by-b0-field-inhomogeneity-using-2d-lineshape-reference-deconvolution
#2
Kirill F Sheberstov, Dmitry O Sinitsyn, Dmitry A Cheshkov, Damien Jeannerat
An efficient approach for reference deconvolution of two-dimensional spectra aiming at the correction of static field inhomogeneity was established. In comparison to known techniques, a great improvement was achieved using the cross-section along the diagonal of the reference peak instead of its full 2D line shape. The method is termed pseudo-2D diagonal deconvolution. The approach developed allows suppressing the two-dimensional peaks tilting caused by the magnetic field inhomogeneity, while keeping the signal-to-noise ratio constant...
June 8, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28646620/atopic-dermatitis-is-inversely-associated-with-hepatitis-b-antigen-positivity-a-population-based-cohort-study
#3
H Y Kim, C W Kim, J Y Choi, D S Yu, J W Kim, K D Han, Y G Park, Y B Lee
BACKGROUND: No clear association between hepatitis B virus (HBV) infection and atopic dermatitis (AD) has been established. Some studies have reported that subjects with HBV had an increased risk of atopy; other studies reported an inverse association between HBV seropositivity and allergic diseases. OBJECTIVE: We evaluated the association between AD and hepatitis B antigen (HBsAg) positivity using Korean National Health and Nutrition Examination Survey data. METHODS: In total, 14,776 participants aged > 19 years were included in the analysis...
June 24, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28646610/measuring-the-societal-impact-of-psoriasis-in-the-united-kingdom-through-a-non-interventional-study-of-patients
#4
C E Griffiths, R Williams, A C Halliday, J A Leman
This cross-sectional study aimed to measure total societal costs of moderate-to-severe, chronic plaque psoriasis in adults, and was conducted at 10 National Health Service hospitals in the United Kingdom between June-November 2014. Data capture was via hand-held electronic devices. Investigators at participating sites identified participants. Eligible patients were ≥18 years of age and diagnosed with moderate-to-severe plaque psoriasis for at least 6 months (Psoriasis Area and Severity Index (PASI) ≥10, and Dermatology Life Quality Index (DLQI) >10)...
June 24, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28646566/structural-neuroimaging-correlates-of-alcohol-and-cannabis-use-in-adolescents-and-adults
#5
Rachel E Thayer, Sophie YorkWilliams, Hollis C Karoly, Amithrupa Sabbineni, Sarah Feldstein Ewing, Angela D Bryan, Kent E Hutchison
BACKGROUND AND AIMS: Chronic alcohol use is associated with lower gray matter volume, and we recently reported that alcohol use showed negative associations with widespread gray matter (GM) volume even among young adults. The current study aimed to test the strength of association between (1) alcohol use and GM volume; (2) alcohol use and white matter (WM) integrity; (3) cannabis use and GM volume; and (4) cannabis use and WM integrity among adults and adolescents. DESIGN AND SETTING: General linear models within large pooled cross-sectional samples of adolescents and adults who had participated in studies collecting substance use and neuroimaging data in the southwestern United States...
June 23, 2017: Addiction
https://www.readbyqxmd.com/read/28646529/notalgia-paresthetica-factors-associated-with-its-perceived-severity-duration-side-and-localization
#6
Calogero Pagliarello, Giuseppe Fabrizi, Beatrice De Felici, Dahiana Casanova, Claudio Feliciani, Sergio Di Nuzzo
BACKGROUND: Notalgia paresthetica (NP) is a disorder characterized by pruritus localized to the patient's back. Little is known about predictors of severity, duration, side, and localization. OBJECTIVE: To identify factors associated with perceived severity, duration, side, and localization of NP. METHODS: In a cross-sectional study, disease severity, duration, side, and localization were compared among the considered variables. Multivariate analysis was used to assess each variable contribution in predicting disease severity and its duration...
June 23, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28646519/the-association-of-health-literacy-with-preventable-ed-visits-a-cross-sectional-study
#7
Meenakshi P Balakrishnan, Jill Boylston Herndon, Jingnan Zhang, Thomas Payton, Jonathan Shuster, Donna L Carden
BACKGROUND: Policy-makers argue that emergency department (ED) visits for conditions preventable with high-quality outpatient care contribute to waste in the healthcare system. However, access to ambulatory care is uneven, especially for vulnerable populations like minorities, the poor and those with limited health literacy. The impact of limited health literacy on ED visits that are preventable with timely, high-quality ambulatory care is unknown. OBJECTIVE: To determine the association of health literacy and preventable ED visits...
June 24, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28646479/negative-body-attitudes-and-sexual-dissatisfaction-in-men-the-mediating-role-of-body-self-consciousness-during-physical-intimacy
#8
Femke van den Brink, Manja Vollmann, Lot C Sternheim, Lotte J Berkhout, Renée A Zomerdijk, Liesbeth Woertman
Previous research indicated that negative attitudes about the body and appearance are common among men and demonstrated that negative body attitudes are associated with negative sexual experiences. The present study investigated the association between body attitudes and sexual dissatisfaction and the mediating role of body self-consciousness during physical intimacy. In a cross-sectional design, 201 Dutch men completed an online survey regarding body attitudes toward muscularity, body fat, height, and genitals, body self-consciousness during physical intimacy, and sexual dissatisfaction...
June 23, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28646476/the-relationship-between-circulating-adiponectin-leptin-and-vaspin-with-bone-mineral-density-bmd-arterial-calcification-and-stiffness-a-cross-sectional-study-in-post-menopausal-women
#9
N Tanna, K Patel, A E Moore, D Dulnoan, S Edwards, G Hampson
OBJECTIVE: To explore the relationship between circulating adiponectin, leptin and vaspin with bone mineral density (BMD), arterial stiffness and vascular calcification in post-menopausal women. We hypothesised that adipokines produced by adipose tissue may be mediators of bone and cardiovascular disease (CVD) and explain, in part, the observed association between osteoporosis and CVD. DESIGN: We studied 386 ambulant community dwelling postmenopausal women aged (mean [SD] 61 [6...
June 23, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28646468/an-investigation-into-the-association-between-demographic-and-morbidity-factors-and-sleep-disturbance
#10
N Mullane, C Bradley
BACKGROUND: The recognition of sleep disorders is important because in the long term, they are associated with numerous deleterious health outcomes. Despite the high prevalence of sleep disorders, they are widely under-diagnosed at general practice level. AIM: This study aims to investigate the association between demographic and morbidity factors, and self-reported sleep disturbance symptoms. METHODS: A quantitative cross-sectional study design was used...
June 23, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28646457/national-survey-among-radiation-oncology-residents-related-to-their-needs-in-geriatric-oncology
#11
Rachel Leifer, Bonnie Bristow, Martine Puts, Shabbir Alibhai, Xingshan Cao, Barbara-Ann Millar, Meredith Giuliani, Tina Hsu, Maureen Trudeau, Rajin Mehta, Ines Menjak, Mireille Norris, Barbara Liu, Francois Gallant, Ewa Szumacher
Currently, there is no formal curriculum addressing geriatric oncology within Canadian radiation oncology (RO) residency programs. Knowledge related to geriatric medicine may help radiation oncologists modify RT based on frailty status and geriatric considerations. Understanding specific learning needs allow program coordinators to align the current curriculum with residents' geriatric oncology learning needs. The purpose of this study is to determine the geriatric oncology educational needs of the Canadian RO residents and to inform Canadian RO residency training...
June 24, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28646344/does-biomarker-information-impact-breast-cancer-patients-preferences-and-physician-recommendation-for-adjuvant-chemotherapy
#12
Ann H Partridge, Karen Sepucha, Anne O'Neill, Kathy D Miller, Emily Baker, Chau T Dang, Donald W Northfelt, George W Sledge, Bryan P Schneider
PURPOSE: This study aimed to examine how biomarker information would impact patients' preferences and physicians' recommendations for adjuvant breast cancer therapy. METHODS: At the 18-month follow-up, participants in a large, double-blind randomized controlled trial of adjuvant chemotherapy with bevacizumab or placebo (E5103) were surveyed about their preferred treatment (either chemotherapy A alone or chemotherapy A+B) in two hypothetical scenarios: (1) without biomarker information; and (2) after learning that they tested positive for a "B-receptor" which modestly increased both the benefit and toxicity expected with chemotherapy A+B...
June 23, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28646330/-imaging-of-vessels-supplying-the-brain
#13
REVIEW
S M Schellong, N Abolmaali, B Voigts, C Stelzner
Nowadays, several technically validated modalities are available for imaging both the extracranial and intracranial segments of arteries supplying blood to the brain. In the acute stroke setting, computed tomography (CT) angiography is of utmost importance because it provides the key diagnostic criteria indicative for the use of catheter-based recanalization techniques. Ultrasound imaging of extracranial arteries is most suitable for detecting an underlying stenosis of the internal carotid artery (ICA) in patients with stroke, transient ischemic attacks (TIA), retinal vessel occlusion and amaurosis fugax...
June 23, 2017: Der Internist
https://www.readbyqxmd.com/read/28646244/increased-soluble-vcam-1-and-normal-p-selectin-in-cystic-fibrosis-a-cross-sectional-study
#14
Jan K Nowak, Irena Wojsyk-Banaszak, Edyta Mądry, Andrzej Wykrętowicz, Patrycja Krzyżanowska, Sławomira Drzymała-Czyż, Agata Nowicka, Andrzej Pogorzelski, Ewa Sapiejka, Wojciech Skorupa, Mariusz Szczepanik, Aleksandra Lisowska, Jaroslaw Walkowiak
PURPOSE: As life expectancy in cystic fibrosis (CF) increases, questions regarding its potential impact on cardiovascular health arise. Soluble vascular cell adhesion molecule 1 (sVCAM-1), P-selectin (sP-selectin) are proposed as biomarkers of cardiovascular disease. We aimed to: compare their concentrations in clinically stable CF patients and healthy subjects (HS) and verify whether they independently correlate with CF characteristics. METHODS: Serum sVCAM-1 and sP-selectin levels were measured using ELISA...
June 23, 2017: Lung
https://www.readbyqxmd.com/read/28646101/serum-androgen-profile-and-physical-performance-in-women-olympic-athletes
#15
Emma Eklund, Bo Berglund, Fernand Labrie, Kjell Carlström, Lena Ekström, Angelica Lindén Hirschberg
BACKGROUND: The role of endogenous androgens for body composition and physical performance in women athletes is still not elucidated. AIM: To examine the serum androgen profile in relation to body composition and physical performance in women Olympic athletes and to compare endocrine variables and body composition to controls. STUDY DESIGN: Cross-sectional study, conducted between 2011 and 2015 at the Women's Health Research Unit, Karolinska University Hospital, Stockholm...
June 23, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28646016/tshb-mrna-is-linked-to-cholesterol-metabolism-in-adipose-tissue
#16
José María Moreno-Navarrete, María Moreno, Francisco Ortega, Gemma Xifra, Shangyu Hong, John M Asara, José C E Serrano, Mariona Jové, Pavlos Pissios, Matthias Blüher, Wifredo Ricart, Manuel Portero-Otin, José Manuel Fernández-Real
Subclinical hypothyroidism is known to be associated with increased serum cholesterol. Since thyroid-stimulating hormone (TSH) exerts an inductor effect on cholesterol biosynthesis, we aimed to investigate the relationship between TSH mRNA and cholesterol metabolism in human adipose tissue (AT). Cross-sectionally, AT TSH-β (TSHB) mRNA was evaluated in 4 independent cohorts in association with serum total and LDL cholesterol, and AT lipidomics. Longitudinally, the effects of statins and of diet and exercise on AT TSHB mRNA were also examined...
June 23, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28645977/vitamin-d-status-and-associated-factors-among-portuguese-older-adults-results-from-the-nutrition-up-65-cross-sectional-study
#17
Alejandro Santos, Teresa F Amaral, Rita S Guerra, Ana S Sousa, Luisa Álvares, Pedro Moreira, Patrícia Padrão, Cláudia Afonso, Nuno Borges
OBJECTIVES: To evaluate vitamin D status and its associated factors in Portuguese older adults from the Nutrition UP 65 study. DESIGN: Cross-sectional observational study. PARTICIPANTS AND METHODS: Nationwide cluster sample of 1500 Portuguese subjects ≥65 years old. Participants were classified, according to US Institute of Medicine cut-offs, as presenting normal 25-hydroxyvitamin D (25(OH)D) levels (≥50.0 nmol/L), at risk of inadequacy (30...
June 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645975/the-impact-of-weight-misperception-on-health-related-quality-of-life-in-korean-adults-knhanes-2007-2014-a-community-based-cross-sectional-study
#18
Susan Park, Sejin Lee, Jinseub Hwang, Jin-Won Kwon
BACKGROUND/OBJECTIVES: Weight perception, especially misperception, might affect health-related quality of life (HRQoL); however, related research is scarce and results remain equivocal. We examined the association between HRQoL and weight misperception by comparing obesity level as measured by body mass index (BMI) and weight perception in Korean adults. METHODS: Study subjects were 43 883 adults aged 19 years or older from cycles IV (2007-2009), V (2010-2012) and VI (2013-2014) of the Korean National Health and Nutrition Examination Survey...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645974/assessing-medical-student-knowledge-and-attitudes-about-shared-decision-making-across-the-curriculum-protocol-for-an-international-online-survey-and-stakeholder-analysis
#19
Marie-Anne Durand, Renata Yen, Paul J Barr, Nan Cochran, Johanna Aarts, France Légaré, Malcolm Reed, A James O'Malley, Peter Scalia, Geneviève Painchaud Guérard, Glyn Elwyn
INTRODUCTION: Shared decision making (SDM) is a goal of modern medicine; however, it is not currently embedded in routine care. Barriers include clinicians’ attitudes, lack of knowledge and training and time constraints. Our goal is to support the development and delivery of a robust SDM curriculum in medical education. Our objective is to assess undergraduate medical students’ knowledge of and attitudes towards SDM in four countries. METHODS AND ANALYSIS: The first phase of the study involves a web-based cross-sectional survey of undergraduate medical students from all years in selected schools across the United States (US), Canada and undergraduate and graduate students in the Netherlands...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645958/factors-predicting-self-reported-medication-low-adherence-in-a-large-sample-of-adults-in-the-us-general-population-a-cross-sectional-study
#20
Michael Feehan, Margaux A Morrison, Casey Tak, Donald E Morisky, Margaret M DeAngelis, Mark A Munger
OBJECTIVES: The study objective was to determine the level and correlates of self-reported medication low adherence in the US general population. SETTING: A 30 min cross-sectional online survey was conducted with a national sample of adults. PARTICIPANTS: 9202 adults (aged 18+) who had filled at least three or more prescriptions at a community pharmacy in the past 12 months. PRIMARY AND SECONDARY OUTCOME MEASURES: Self-reported medication adherence was measured with the 8-item Morisky Medication Adherence Scale...
June 23, 2017: BMJ Open
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