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https://www.readbyqxmd.com/read/27865618/actinidia-arguta-supplementation-protects-aorta-and-liver-in-rats-with-induced-hypercholesterolemia
#1
Maria Leontowicz, Hanna Leontowicz, Iwona Jesion, Wojciech Bielecki, Katarzyna Najman, Piotr Latocha, Yong-Seo Park, Shela Gorinstein
There are no published results focusing on the study of hardy kiwifruit as a supplementation to the atherogenic diet. We hypothesized that hardy kiwifruit (Actinidia arguta (A. arguta)) from Poland possess better pro-healthy action than two Asian varieties (Hayward and Bidan). We tested this hypothesis by measuring the metabolic reactions of rats loaded with 1% cholesterol and supplemented with 5% of hardy kiwifruit (A. arguta), Hayward, or Bidan in their diets. The experiment was performed on 71 male Wistar rats...
September 30, 2016: Nutrition Research
https://www.readbyqxmd.com/read/27807452/child-survival-strategies-assessment-of-knowledge-and-practice-of-rural-women-of-reproductive-age-in-cross-river-state-nigeria
#2
Aniekan Jumbo Etokidem, Ofonime Johnson
Introduction. Nigeria is one of the five countries that account for about 50% of under-five mortality in the world. The objective of this study was to assess the knowledge and practice of child survival strategies among rural community caregivers in Cross River State of Nigeria. Materials and Methods. This descriptive cross-sectional survey used a pretested questionnaire to obtain information from 150 women of reproductive age. Data analysis was done using SPSS version 20. Results. The child survival strategy known to most of the respondents was oral rehydration therapy as indicated by 98% followed by female education by 73...
2016: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/27707469/description-of-plastic-remains-found-in-the-stomach-contents-of-the-jumbo-squid-dosidicus-gigas-landed-in-ecuador-during-2014
#3
Rigoberto Rosas-Luis
Squids are active and opportunistic predators that feed on a wide range of prey. Their active movements in the water column and their voracity promote a high consumption of food. In the pelagic environment off Ecuador, marine pollution is characterized by plastic debris with a mainland origin, including plastics trash of fishing gears. The objective of this work was to describe the presence of plastic remains in the stomach contents of Dosidicus gigas caught off the coast of Ecuador. Results demonstrated that 12% of the stomachs contained plastic remains...
October 1, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27663505/the-gastric-acid-pocket-is-attenuated-in-h-pylori-infected-subjects
#4
David R Mitchell, Mohammad H Derakhshan, Angela A Wirz, Clare Orange, Stuart A Ballantyne, James J Going, Kenneth E L McColl
OBJECTIVE: Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in Helicobacter pylori positive and negative volunteers in a Western population. DESIGN: We studied 31 H. pylori positive and 28 H. pylori negative volunteers, matched for age, gender and body mass index. Jumbo biopsies were taken at 11 predetermined locations from the gastro-oesophageal junction and stomach. Combined high-resolution pH metry (12 sensors) and manometry (36 sensors) was performed for 20 min fasted and 90 min postprandially...
September 23, 2016: Gut
https://www.readbyqxmd.com/read/27619796/characteristics-and-complete-genome-analysis-of-a-novel-jumbo-phage-infecting-pathogenic-bacillus-pumilus-causing-ginger-rhizome-rot-disease
#5
Yihui Yuan, Meiying Gao
Tailed phages with genomes larger than 200 kbp are classified as jumbo phage and exhibit extremely high diversity. In this study, a novel jumbo phage, vB_BpuM_BpSp, infecting pathogenic Bacillus pumilus, the cause of ginger rhizome rot disease, was isolated. Notable features of phage vB_BpuM_BpSp are the large phage capsid of 137 nm and baseplate-attached curly tail fibers. The genome of the phage is 255,569 bp in size with G+C content of 25.9 %, and it shows low similarity to known biological entities...
December 2016: Archives of Virology
https://www.readbyqxmd.com/read/27588938/the-role-of-water-on-the-structure-and-mechanical-properties-of-a-thermoplastic-natural-block-co-polymer-from-squid-sucker-ring-teeth
#6
Clément Rieu, Luca Bertinetti, Roman Schuetz, Cesar Ca Salinas-Zavala, James C Weaver, Peter Fratzl, Ali Miserez, Admir Masic
Hard biological polymers exhibiting a truly thermoplastic behavior that can maintain their structural properties after processing are extremely rare and highly desirable for use in advanced technological applications such as 3D-printing, biodegradable plastics and robust composites. One exception are the thermoplastic proteins that comprise the sucker ring teeth (SRT) of the Humboldt jumbo squid (Dosidicus gigas). In this work, we explore the mechanical properties of reconstituted SRT proteins and demonstrate that the material can be re-shaped by simple processing in water and at relatively low temperature (below 100 °C)...
2016: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/27563033/genome-sequence-of-jumbo-phage-vb_abam_me3-of-acinetobacter-baumanni
#7
Colin Buttimer, Lisa O'Sullivan, Mohamed Elbreki, Horst Neve, Olivia McAuliffe, R Paul Ross, Colin Hill, Jim O'Mahony, Aidan Coffey
Bacteriophage (phage) vB_AbaM_ME3 was previously isolated from wastewater effluent using the propagating host Acinetobacter baumannii DSM 30007. The full genome was sequenced, revealing it to be the largest Acinetobacter bacteriophage sequenced to date with a size of 234,900 bp and containing 326 open reading frames (ORFs).
2016: Genome Announcements
https://www.readbyqxmd.com/read/27562100/acute-and-long-term-outcomes-in-a-drosophila-melanogaster-model-of-classic-galactosemia-occur-independently-of-galactose-1-phosphate-accumulation
#8
Jennifer M I Daenzer, Patricia P Jumbo-Lucioni, Marquise L Hopson, Kerry R Garza, Emily L Ryan, Judith L Fridovich-Keil
Classic galactosemia (CG) is a potentially lethal inborn error of metabolism that results from the profound loss of galactose-1-phosphate uridylyltransferase (GALT), the second enzyme in the Leloir pathway of galactose metabolism. Neonatal detection and dietary restriction of galactose minimizes or resolves the acute sequelae of CG, but fails to prevent the long-term complications experienced by a majority of patients. One of the substrates of GALT, galactose-1-phosphate (Gal-1P), accumulates to high levels in affected infants, especially following milk exposure, and has been proposed as the key mediator of acute and long-term pathophysiology in CG...
November 1, 2016: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/27466186/coordinated-movement-neuromuscular-synaptogenesis-and-trans-synaptic-signaling-defects-in-drosophila-galactosemia-models
#9
Patricia P Jumbo-Lucioni, William M Parkinson, Danielle L Kopke, Kendal Broadie
The multiple galactosemia disease states manifest long-term neurological symptoms. Galactosemia I results from loss of galactose-1-phosphate uridyltransferase (GALT), which converts galactose-1-phosphate + UDP-glucose to glucose-1-phosphate + UDP-galactose. Galactosemia II results from loss of galactokinase (GALK), phosphorylating galactose to galactose-1-phosphate. Galactosemia III results from the loss of UDP-galactose 4'-epimerase (GALE), which interconverts UDP-galactose and UDP-glucose, as well as UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine...
July 27, 2016: Human Molecular Genetics
https://www.readbyqxmd.com/read/27267368/transcriptomic-profiling-of-melon-necrotic-spot-virus-infected-melon-plants-revealed-virus-strain-and-plant-cultivar-specific-alterations
#10
Cristina Gómez-Aix, Laura Pascual, Joaquín Cañizares, María Amelia Sánchez-Pina, Miguel A Aranda
BACKGROUND: Viruses are among the most destructive and difficult to control plant pathogens. Melon (Cucumis melo L.) has become the model species for the agriculturally important Cucurbitaceae family. Approaches that take advantage of recently developed genomic tools in melon have been extremely useful for understanding viral pathogenesis and can contribute to the identification of target genes for breeding new resistant cultivars. In this work, we have used a recently described melon microarray for transcriptome profiling of two melon cultivars infected with two strains of Melon necrotic spot virus (MNSV) that only differ on their 3'-untranslated regions...
2016: BMC Genomics
https://www.readbyqxmd.com/read/27242758/proteomic-analysis-of-a-novel-bacillus-jumbo-phage-revealing-glycoside-hydrolase-as-structural-component
#11
Yihui Yuan, Meiying Gao
Tailed phages with genomes of larger than 200 kbp are classified as Jumbo phages and exhibited extremely high uncharted diversity. The genomic annotation of Jumbo phage is often disappointing because most of the predicted proteins, including structural proteins, failed to make good hits to the sequences in the databases. In this study, 23 proteins of a novel Bacillus Jumbo phage, vB_BpuM_BpSp, were identified as phage structural proteins by the structural proteome analysis, including 14 proteins of unknown function, 5 proteins with predicted function as structural proteins, a glycoside hydrolase, a Holliday junction resolvase, a RNA-polymerase β-subunit, and a host-coding portal protein, which might be hijacked from the host strain during phage virion assembly...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27196581/hiatus-hernia-in-healthy-volunteers-is-associated-with-intrasphincteric-reflux-and-cardiac-mucosal-lengthening-without-traditional-reflux
#12
Elaine V Robertson, Mohammad H Derakhshan, Angela A Wirz, David R Mitchell, James J Going, Andrew W Kelman, Stuart A Ballantyne, Kenneth E L McColl
BACKGROUND AND AIMS: Hiatus hernia (HH) is a key mediator of gastro-oesophageal reflux disease but little is known about its significance in the general population. We studied the structure and function of the gastro-oesophageal junction in healthy volunteers with and without HH. METHODS: We compared 15 volunteers with HH, detected by endoscopy or MRI scan, but without gastro-oesophageal reflux disease with 15 controls matched for age, gender and body weight. Jumbo biopsies were taken across the squamocolumnar junction (SCJ)...
April 25, 2016: Gut
https://www.readbyqxmd.com/read/27081857/two-asian-jumbo-phages-%C3%AF-rsl2-and-%C3%AF-rsf1-infect-ralstonia-solanacearum-and-show-common-features-of-%C3%AF-kz-related-phages
#13
Anjana Bhunchoth, Romain Blanc-Mathieu, Tomoko Mihara, Yosuke Nishimura, Ahmed Askora, Namthip Phironrit, Chalida Leksomboon, Orawan Chatchawankanphanich, Takeru Kawasaki, Miyako Nakano, Makoto Fujie, Hiroyuki Ogata, Takashi Yamada
Jumbo phages infecting Ralstonia solanacearum were isolated in Thailand (ϕRSL2) and Japan (ϕRSF1). They were similar regarding virion morphology, genomic arrangement, and host range. Phylogenetic and proteomic tree analyses demonstrate that the ϕRSL2 and ϕRSF1 belong to a group of evolutionary related phages, including Pseudomonas phages ϕKZ, 201ϕ2-1 and all previously described ϕKZ-related phages. Despite conserved genomic co-linearity between the ϕRSL2 and ϕRSF1, they differ in protein separation patterns...
July 2016: Virology
https://www.readbyqxmd.com/read/27047229/clinical-evaluation-and-surgical-options-in-acetabular-reconstruction-a-literature-review
#14
REVIEW
Asim Qamar Ahmad, Ran Schwarzkopf
The purpose of this paper is to review the clinical indications for acetabular reconstruction in patients with underlying peri-prosthetic segmental and cavitary defects, evaluate steps in pre-operative planning, and present the American Academy of Orthopaedic Surgeons (AAOS) and Paprosky classification systems to categorize acetabular defects. We also present a review of the current surgical techniques to reconstruct the acetabular socket which includes a cementless acetabular component with morselized bone, structural allograft, jumbo and oblong cups, reinforcement rings, bone cages, custom triflange acetabular constructs, and trabecular metal components...
December 2015: Journal of Orthopaedics
https://www.readbyqxmd.com/read/27042202/apoptosis-inducing-effects-of-jujube-z%C3%A7-o-seed-extracts-on-human-jurkat-leukemia-t-cells
#15
Natthanan Taechakulwanijya, Natthida Weerapreeyakul, Sahapat Barusrux, Sirithorn Siriamornpun
BACKGROUND: Jujube (Zǎo) seeds exhibited anticancer effects and used in Chinese medicine for many years. This study aims to investigate the apoptosis-inducing effects of seed extracts from eight different cultivated species ('Apple', 'Bombay', 'Jumbo', 'Kaew', 'Nomsod', 'Rianthong', 'Samros', and 'Taiwan') on human Jurkat leukemia T cells. METHODS: We evaluated the effects of seed extracts from eight jujube cultivated species on human Jurkat leukemia T cells. The crude seed extracts were prepared sequentially by using water, 95 % ethanol, dichloromethane, ethyl acetate, chloroform or hexane...
2016: Chinese Medicine
https://www.readbyqxmd.com/read/26785574/-a-study-on-feeding-ecology-and-migration-patterns-of-dosidicus-gigas-off-peru-using-stable-isotope-analysis
#16
Yi Gong, Xin-jun Chen, Yun-kai Li, Meng-jie Han
As a pelagic cephalopod and one of the main target species of Chinese distant water fishery, jumbo squids (Dosidicus gigas) play a major role in the marine ecosystems of the eastern Pacific. Understanding the feeding ecology and migration patterns of jumbo squids is of importance for better utilizing the resources. The isotopic signatures of gladius, have been proved to be a powerful tool to reveal high resolution and ontogenic variations in individual foraging strategies of squids; which is an archival tissue with no elemental turnover after formation...
September 2015: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/26626773/the-use-of-structural-distal-femoral-allograft-for-acetabular-reconstruction-of-paprosky-type-iiia-defects-at-a-mean-21-years-of-follow-up
#17
Nicholas M Brown, Joe Morrison, Scott M Sporer, Wayne G Paprosky
BACKGROUND: Revision total hip arthroplasty in patients with a nonsupportive superior acetabulum often requires secondary augmentation beyond a hemispherical cup to achieve reliable fixation. Treatment options include using a higher hip center, jumbo cup, custom triflange implant, cages, or filling the superior defect with a bilobed implant, structural allograft, or metal augments. We previously reported a cohort of 31 patients treated with porous-coated hemispherical cups and distal femoral allograft for Paprosky type IIIA acetabular defects...
March 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/26545637/role-of-the-cold-biopsy-technique-in-diminutive-and-small-colonic-polyp-removal-a-systematic-review-and-meta-analysis
#18
REVIEW
Dany Raad, Priyam Tripathi, Gregory Cooper, Yngve Falck-Ytter
BACKGROUND AND AIMS: The most commonly detected polyps during screening colonoscopy are diminutive and small polyps, and therefore endoscopic treatment of those polyps is a daily routine for every colonoscopist. The primary aim of this study was to compare the complete eradication rate of diminutive and small colorectal polyps using cold biopsy versus other techniques, because randomized controlled trials have shown conflicting results. METHODS: In March 2015 we searched for randomized controlled trials in Medline, EMBASE, and ISI the Web of Science, starting with their dates of inception, and abstracts of pertinent scientific meetings (eg, American College of Gastroenterology, Digestive Disease Week)...
March 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/26543509/pill-properties-that-cause-dysphagia-and-treatment-failure
#19
Jeremy Fields, Jorge T Go, Konrad S Schulze
BACKGROUND: Pills (tablets and capsules) are widely used to administer prescription drugs or to take supplements such as vitamins. Unfortunately, little is known about how much effort it takes Americans to swallow these various pills. More specifically, it is not known to what extent hard-to-swallow pills might affect treatment outcomes (eg, interfering with adherence to prescribed medications or causing clinical complications). It is also unclear which properties (eg, size, shape, or surface texture) Americans prefer or reject for their pills...
December 2015: Current Therapeutic Research, Clinical and Experimental
https://www.readbyqxmd.com/read/26467611/custom-acetabular-cages-offer-stable-fixation-and-improved-hip-scores-for-revision-tha-with-severe-bone-defects
#20
Huiwu Li, Xinhua Qu, Yuanqing Mao, Kerong Dai, Zhenan Zhu
BACKGROUND: Revision THA is particularly challenging in hips with severe acetabular bone loss. When the extent or geometry of the acetabular bone loss precludes more-straightforward techniques such as jumbo hemispheric cementless shells, reconstruction with morselized allograft protected by a custom cage may offer an alternative, but, to our knowledge, few series have reported on results with this approach. QUESTIONS/PURPOSES: For patients with severe (Paprosky IIIB) defects, we asked: do individualized custom cages result in (1) improved Harris hip scores; (2) restoration of hip center; and (3) a low incidence of surgical complications? METHODS: Twenty-six patients (26 hips) with a massive acetabular defect were involved in this study from 2003 to 2013...
March 2016: Clinical Orthopaedics and related Research
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