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https://www.readbyqxmd.com/read/29089853/effect-of-amidated-low-methoxyl-pectin-on-physicochemical-characteristics-of-jumbo-squid-dosidicus-gigas-mantle-muscle-gels
#1
Juan C Ramirez-Suarez, Andrés Álvarez-Armenta, Guillermina García-Sánchez, Ramón Pacheco-Aguilar, Susana M Scheuren-Acevedo, Miguel A Mazorra-Manzano, Agustín Rascón-Chu
Jumbo squid (Dosidicus gigas) muscle proteins show low functionality with limited use in gel products. This work aims to assess the influence of adding the natural and commercially available fibre, amidated low-methoxyl pectin (at 0.5, 1.0, 1.5, 2.0 and 3.0%), on the physicochemical and functional characteristics of jumbo squid (Dosidicus gigas) mantle muscle gels. The addition of 0.5% fibre showed an immediate effect on the gel texture profile analysis, improving hardness (p<0.05) from (3.4±0.7) N of the control (no added fibre) to (5...
September 2017: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/29073989/drug-policy-in-the-czech-republic
#2
Jana Skoupá
BACKGROUND: The legal background of the current pharmaceutical pricing and reimbursement (P&R) setting in the Czech Republic is based on Act 48/1997. Since 2008, the P&R process has been coordinated by the State Institute for Drug Control, which is the main stakeholder in the decision-making process; marketing authorization holders and insurance funds (IFs) also participate. OBJECTIVES: To present a general overview of the current Czech health care system and its P&R principles...
September 2017: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29042498/capsids-and-genomes-of-jumbo-sized-bacteriophages-reveal-the-evolutionary-reach-of-the-hk97-fold
#3
Jianfei Hua, Alexis Huet, Carlos A Lopez, Katerina Toropova, Welkin H Pope, Robert L Duda, Roger W Hendrix, James F Conway
Large icosahedral viruses that infect bacteria represent an extreme of the coevolution of capsids and the genomes they accommodate. One subset of these large viruses is the jumbophages, tailed phages with double-stranded DNA genomes of at least 200,000 bp. We explored the mechanism leading to increased capsid and genome sizes by characterizing structures of several jumbophage capsids and the DNA packaged within them. Capsid structures determined for six jumbophages were consistent with the canonical phage HK97 fold, and three had capsid geometries with novel triangulation numbers (T=25, T=28, and T=52)...
October 17, 2017: MBio
https://www.readbyqxmd.com/read/28993083/acetabular-revision-arthroplasty-using-an-uncemented-deep-profile-jumbo-component-a-ten-to-sixteen-year-follow-up-study
#4
Jeffrey R McLaughlin, Kyla R Lee
BACKGROUND: The purpose of this study is to evaluate the outcome of revision total hip arthroplasty using an uncemented deep profile jumbo acetabular component in patients who had been followed for a minimum of 10 years postoperatively. METHODS: Between 1997 and 2001, 61 revision total hip arthroplasties were performed in 58 patients, with use of the +5 Deep Profile acetabular shell. The outcome with regard to retention vs re-revision of the acetabular component was determined for every hip...
September 14, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28982391/the-impact-of-early-thromboelastography-directed-therapy-in-trauma-resuscitation
#5
Mohamed Mohamed, Karl Majeske, Gul R Sachwani, Kristin Kennedy, Mina Salib, Michael McCann
BACKGROUND: Conventional coagulation tests do not provide an accurate representation of the complex nature of trauma induced coagulopathy. Thrombelastography provides a prompt global overview of all dynamic sequential aspects of trauma induced coagulopathy. The objective of this study was to evaluate the impact of using thrombelastography on blood products utilization, crystalloids utilization, hospital, and intensive care using length of stay, and cost savings. METHODS: We retrospectively reviewed 134 patients (May of 2012 to February of 2015) meeting Class I trauma activation...
October 5, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28955680/acetabular-cup-revision
#6
EDITORIAL
Young-Ho Kim
The use of acetabular cup revision arthroplasty is on the rise as demands for total hip arthroplasty, improved life expectancies, and the need for individual activity increase. For an acetabular cup revision to be successful, the cup should gain stable fixation within the remaining supportive bone of the acetabulum. Since the patient's remaining supportive acetabular bone stock plays an important role in the success of revision, accurate classification of the degree of acetabular bone defect is necessary. The Paprosky classification system is most commonly used when determining the location and degree of acetabular bone loss...
September 2017: Hip & Pelvis
https://www.readbyqxmd.com/read/28946369/the-effects-of-different-dry-roast-parameters-on-peanut-quality-using-an-industrial-belt-type-roaster-simulator
#7
Xiaolei Shi, Lisa O Dean, Jack P Davis, K P Sandeep, Timothy H Sanders
Peanuts roasted to equivalent surface colors at different temperature/time combinations can vary substantially in chemical and physical properties related to product quality. This study used a pilot plant scale roaster that simulates the configurations of one of the most common industrial roaster, a multi-zone belt roaster. Jumbo-size runner-type peanuts were systematically roasted at 5 temperatures (149-204°C) to three Hunter l-values of 53, 48.5, and 43, corresponding to light, medium, and dark roasts. Moisture and tocopherol contents were more closely correlated with roast color rather than temperature, with exceptions at 149°C...
February 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28945109/reduction-of-syndecan-transcript-levels-in-the-insulin-producing-cells-affects-glucose-homeostasis-in-adult-drosophila-melanogaster
#8
Jonathan L Warren, Eneida Hoxha, Patricia Jumbo-Lucioni, Maria De Luca
Signaling by direct cell-matrix interactions has been shown to impact the transcription, secretion, and storage of insulin in mammalian β cells. However, more research is still needed in this area. Syndecans are transmembrane heparan sulfate proteoglycans that function independently and in synergy with integrin-mediated signaling to mediate cell adhesion to the extracellular matrix. In this study, we used the model organism Drosophila melanogaster to determine whether knockdown of the Syndecan (Sdc) gene expression specifically in the insulin-producing cells (IPCs) might affect insulin-like peptide (ILP) production and secretion...
November 2017: DNA and Cell Biology
https://www.readbyqxmd.com/read/28883505/channel-formation-and-membrane-deformation-via-sterol-aided-polymorphism-of-amphidinol-3
#9
Masayuki Iwamoto, Ayumi Sumino, Eri Shimada, Masanao Kinoshita, Nobuaki Matsumori, Shigetoshi Oiki
Amphidinol 3 (AM3) is an anti-fungal polyene extracted from a marine dinoflagellate. Here, we examined the ion channel activity and membrane-embedded structure of AM3 using a lipid bilayer method and atomic force microscopy (AFM). AM3 exhibited large-conductance (~1 nS) and non-selective single-channel activity only when sterols were present in the membrane leaflet of the AM3-added side. The variable conductance suggests the formation of a multimeric barrel-stave pore. At high AM3 concentrations, giant-conductance "jumbo" channels (~40 nS) emerged...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28812188/comparative-efficacy-of-cold-polypectomy-techniques-for-diminutive-colorectal-polyps-a-systematic-review-and-network-meta-analysis
#10
Yoon Suk Jung, Chan Hyuk Park, Eunwoo Nam, Chang Soo Eun, Dong Il Park, Dong Soo Han
BACKGROUND: Although cold polypectomy techniques are preferred over polypectomy with electrocautery in the management of diminutive polyps, comprehensive comparisons among various cold polypectomy techniques have not yet been fully performed. METHODS: We searched for all relevant randomized controlled trials published up until October 2016 examining the efficacy of cold polypectomy techniques for diminutive polyps. Cold polypectomy techniques were classified as cold forceps polypectomy (CFP), jumbo forceps polypectomy (JFP), traditional cold snare polypectomy (CSP), and dedicated CSP, according to the type of device...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28659872/replications-of-two-closely-related-groups-of-jumbo-phages-show-different-level-of-dependence-on-host-encoded-rna-polymerase
#11
Takeru Matsui, Genki Yoshikawa, Tomoko Mihara, Orawan Chatchawankanphanich, Takeru Kawasaki, Miyako Nakano, Makoto Fujie, Hiroyuki Ogata, Takashi Yamada
Ralstonia solanacearum phages ΦRP12 and ΦRP31 are jumbo phages isolated in Thailand. Here we show that they exhibit similar virion morphology, genome organization and host range. Genome comparisons as well as phylogenetic and proteomic tree analyses support that they belong to the group of ΦKZ-related phages, with their closest relatives being R. solanacearum phages ΦRSL2 and ΦRSF1. Compared with ΦRSL2 and ΦRSF1, ΦRP12 and ΦRP31 possess larger genomes (ca. 280 kbp, 25% larger). The replication of ΦRP12 and ΦRP31 was not affected by rifampicin treatment (20 μg/ml), suggesting that phage-encoded RNAPs function to start and complete the infection cycle of these phages without the need of host-encoded RNAPs...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28493241/-the-use-of-jumbo-cups-in-revision-total-hip-arthroplasty
#12
Philipp von Roth, Georgi I Wassilew
Extra-large uncemented jumbo cups are among the most common methods of acetabular revision. Jumbo cups do not contribute to bone stock restoration, and in the case of a subsequent revision, an even larger bone defect is to be expected. Thus, understanding long-term survival is essential. The present article discusses the literature relevant to this topic and addresses technical and implant-specific characteristics of jumbo cups. In summary, jumbo cups show an acceptable long-term survival rate, with aseptic loosening as the most common reason for revision and dislocation being the most common complication...
October 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28352259/jumbo-bacteriophages-an-overview
#13
Yihui Yuan, Meiying Gao
Tailed bacteriophages with genomes larger than 200 kbp are classified as Jumbo phages, and are rarely isolated by conventional methods. These phages are designated "jumbo" owing to their most notable features of a large phage virion and large genome size. However, in addition to these, jumbo phages also exhibit several novel characteristics that have not been observed for phages with smaller genomes, which differentiate jumbo phages in terms of genome organization, virion structure, progeny propagation, and evolution...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28316959/comparative-study-of-peripheral-rim-fixation-using-jumbo-cup-in-revisional-hip-arthroplasty
#14
Woo-Lam Jo, Young-Wook Lim, Jin-Hyung Im, Seung-Chan Kim, Soon-Yong Kwon, Yong-Sik Kim
PURPOSE: It is challenging procedure to revise acetabular component in acetabulum with severe bone defect or deformity. The jumbo cup is good option for revisional arthroplasty in large bone defect. The purpose of this study is to compare the prognosis of revisional total hip arthroplasty using jumbo cup with peripheral rim fixation and no rim fixation. MATERIALS AND METHODS: We included the patients who had performed acetabular revisional total hip arthroplasty from January 2002 to March 2015 in our institute...
March 2017: Hip & Pelvis
https://www.readbyqxmd.com/read/28250902/successful-endoscopic-fragmentation-of-large-hardened-fecaloma-using-jumbo-forceps
#15
Yasumasa Matsuo, Hiroshi Yasuda, Hiroyasu Nakano, Miki Hattori, Midori Ozawa, Yoshinori Sato, Yoshiko Ikeda, Shun-Ichiro Ozawa, Masaki Yamashita, Hiroyuki Yamamoto, Fumio Itoh
We present a rare case of fecaloma, 7 cm in size, in the setting of systemic scleroderma. A colonoscopy revealed a giant brown fecaloma occupying the lumen of the colon and a colonic ulcer that was caused by the fecaloma. The surface of the fecaloma was hard, large and slippery, and fragmentation was not possible despite the use of various devices, including standard biopsy forceps, an injection needle, and a snare. However, jumbo forceps were able to shave the surface of the fecaloma and break it successfully by repeated biting for 6 h over 2 d...
February 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28243820/digestion-of-ceramide-2-aminoethylphosphonate-a-sphingolipid-from-the-jumbo-flying-squid-dosidicus-gigas-in-mice
#16
COMPARATIVE STUDY
Nami Tomonaga, Yuki Manabe, Tatsuya Sugawara
Ceramide 2-aminoethylphosphonate (CAEP), a sphingophosphonolipid containing a carbon-phosphorus bond, is frequently found in marine organisms and has a unique triene type of sphingoid base in its structure. CAEP has not been evaluated as a food ingredient, although it is generally contained in Mollusca organisms such as squids and shellfish, which are consumed worldwide. In this study, we aimed to elucidate the effects of CAEP as a food component by evaluating the digestion of CAEP extracted from the skin of the jumbo flying squid Dosidicus gigas...
April 2017: Lipids
https://www.readbyqxmd.com/read/28214460/managing-acetabular-defects-in-total-hip-arthroplasty
#17
REVIEW
Brian Park, Frank Liporace, Scott Marwin
With the aging population and rising incidence of primary total joint arthroplasty has come the increasing incidence of revision total hip arthroplasties. One challenge in revision total hip arthroplasty is dealing with acetabular defects. The orthopaedic surgeon who chooses to take on these challenges requires a proper method for the evaluation of these defects as well as an evidence-based treatment algorithm. Initial assessment requires appropriate use and interpretation of imaging modalities such as x-rays and computed tomography...
January 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28196958/transcription-profiling-of-bacillus-subtilis-cells-infected-with-ar9-a-giant-phage-encoding-two-multisubunit-rna-polymerases
#18
Daria Lavysh, Maria Sokolova, Marina Slashcheva, Konrad U Förstner, Konstantin Severinov
Bacteriophage AR9 is a recently sequenced jumbo phage that encodes two multisubunit RNA polymerases. Here we investigated the AR9 transcription strategy and the effect of AR9 infection on the transcription of its host, Bacillus subtilis Analysis of whole-genome transcription revealed early, late, and continuously expressed AR9 genes. Alignment of sequences upstream of the 5' ends of AR9 transcripts revealed consensus sequences that define early and late phage promoters. Continuously expressed AR9 genes have both early and late promoters in front of them...
February 14, 2017: MBio
https://www.readbyqxmd.com/read/28174560/things-are-getting-hairy-enterobacteria-bacteriophage-vb_pcam_cbb
#19
Colin Buttimer, Hanne Hendrix, Hugo Oliveira, Aidan Casey, Horst Neve, Olivia McAuliffe, R Paul Ross, Colin Hill, Jean-Paul Noben, Jim O'Mahony, Rob Lavigne, Aidan Coffey
Enterobacteria phage vB_PcaM_CBB is a "jumbo" phage belonging to the family Myoviridae. It possesses highly atypical whisker-like structures along the length of its contractile tail. It has a broad host range with the capability of infecting species of the genera Erwinia, Pectobacterium, and Cronobacter. With a genome of 355,922 bp, excluding a predicted terminal repeat of 22,456 bp, phage CBB is the third largest phage sequenced to date. Its genome was predicted to encode 554 ORFs with 33 tRNAs. Based on prediction and proteome analysis of the virions, 29% of its predicted ORFs could be functionally assigned...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28109677/effect-of-pulsed-ultrasound-on-the-physicochemical-characteristics-and-emulsifying-properties-of-squid-dosidicus-gigas-mantle-proteins
#20
O A Higuera-Barraza, W Torres-Arreola, J M Ezquerra-Brauer, F J Cinco-Moroyoqui, J C Rodríguez Figueroa, E Marquez-Ríos
Food technologists are always looking to improve the functional properties of proteins. In this sense, in last years ultrasound has been used to improve some functional properties. For this reason, and considering that jumbo squid is an important fishery in northwest Mexico, the purpose of this research was to determine the effect of pulsed ultrasound on the physicochemical characteristics and emulsifying properties of squid (Dosidicus gigas) mantle proteins. Pulsed ultrasound (20kHz, 20, and 40% amplitude) was applied for 30, 60, and 90s to a protein extract prepared from giant squid mantle causing an increase (p<0...
January 12, 2017: Ultrasonics Sonochemistry
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