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https://www.readbyqxmd.com/read/28749733/cytogenetic-surveillance-of-persons-occupationally-exposed-to-genotoxic-chemicals
#1
Jelena Pajic, Dubravka Jovicic, Aleksandar Ps Milovanovic
Human genotoxic exposures can occur environmentally, occupationally or medicinally. The aim of this study was to assess cytogenetic damage (chromosomal aberrations and micronuclei) in persons exposed to chemical agents in medical, agricultural and industrial occupations. The results showed influences of age, gender, occurrence and duration of exposure on the extent of cytogenetic damage, but no influence of smoking. Persons exposed to pesticides were allocated significantly higher values of most examined parameters...
July 27, 2017: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/28749489/optimization-of-ultra-performance-liquid-chromatography-uplc-with-fluorescence-detector-fld-method-for-the-quantitative-determination-of-selected-neurotransmitters-in-rat-brain
#2
Joanna Stragierowicz, Adam Daragó, Sławomir Brzeźnicki, Anna Kilanowicz
BACKGROUND: Glutamate (Glu) and γ-aminobutyric acid (GABA) are the main neurotransmitters in the central nervous system for excitatory and inhibitory processes, respectively. Monitoring these neurotransmitters is an essential tool in establishing pathological functions, among others in terms of occupational exposure to toxic substances. MATERIAL AND METHODS: We present modification of the HPLC (high-performance liquid chromatography) to the UPLC (ultra-performance liquid chromatography) method for the simultaneous determination of glutamate and γ-aminobutyric acid in a single injection...
July 26, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28749105/compensation-for-asbestos-related-diseases-in-japan-utilization-of-standard-classifications-of-industry-and-occupations
#3
Kittisak Sawanyawisuth, Sugio Furuya, Eun-Kee Park, Jun-Pyo Myong, Juan Pablo Ramos-Bonilla, Odgerel Chimed Ochir, Ken Takahashi
Background: Asbestos-related diseases (ARD) are occupational hazards with high mortality rates. To identify asbestos exposure by previous occupation is the main issue for ARD compensation for workers. This study aimed to identify risk groups by applying standard classifications of industries and occupations to a national database of compensated ARD victims in Japan. Methods: We identified occupations that carry a risk of asbestos exposure according to the International Standard Industrial Classification of All Economic Activities (ISIC)...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28747235/journalists-occupational-stress-a-comparative-study-between-reporting-critical-events-and-domestic-news
#4
Susana Monteiro, Alexandra Marques-Pinto
Nowadays, journalism is considered a stressful occupation, not only due to the stress perceived in journalists' daily work but also due to the critical, potentially traumatic events they report. However, research on journalists' occupational stress in both these professional settings is still scarce. This study aims to characterize and compare occupational stress variables perceived by journalists in their daily work and in critical scenarios. Taking the Holistic Model of Occupational Stress by Nelson and Simmons (2003) as a framework, 25 Portuguese journalists, all with experience in reporting critical events, were interviewed on their perceptions of some core variables of the model: occupational stressors, distress and eustress emotional reactions, and the consequences of these experiences on their well-being...
July 27, 2017: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/28746895/effects-on-human-bronchial-epithelial-cells-following-low-dose-chronic-exposure-to-nanomaterials-a-6-month-transformation-study
#5
Santosh Phuyal, Mayes Kasem, Laura Rubio, Hanna L Karlsson, Ricard Marcos, Vidar Skaug, Shanbeh Zienolddiny
The most plausible exposure route to manufactured nanomaterials (MNM) remains pulmonary inhalation. Yet, few studies have attempted to assess carcinogenic properties in vitro following long-term exposure of human pulmonary cells to low and occupationally relevant doses. The most advanced in vitro tests for carcinogenicity, the cell transformation assay (CTA), relying mostly on rodent cells and short-term exposure. We hypothesized that long-term exposure of human bronchial epithelial cells with a normal phenotype could be a valuable assay for testing carcinogenicity of nanomaterials...
July 23, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28743683/cross-sectional-study-of-chronic-obstructive-pulmonary-disease-prevalence-among-smokers-ex-smokers-and-never-smokers-in-almaty-kazakhstan-study-protocol
#6
Almaz Sharman, Baurzhan Zhussupov, Dana Sharman, Assel Stambekova, Sattar Yeraliyev
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is significantly underdiagnosed in Kazakhstan, and there is no previously conducted study on COPD prevalence in the country. OBJECTIVE: The purpose of this study is to assess the prevalence of COPD among individuals aged 40 to 59 years based on results of spirometry before and after bronchodilator, presence of structural changes in the lungs (emphysema, inflammatory changes, and thickening of the walls of the large and small airways) detected by computer tomography, and the symptoms of COPD...
July 25, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28742310/radon-as-a-risk-factor-of-lung-cancer
#7
Ewa Gawełek, Bogna Drozdzowska, Anna Fuchs
Radon is the second leading cause of lung cancer after smoking. Indoor radon concentration poses a significant and potentially subject to the prevention risk factor of lung cancer development. The paper present the history of studies assessing occupational and indoor radon exposure and an impact of international organizations for raise public and political awareness about the consequences of long term exposure to residential radon, resulting in the European Directive 2013/59/Euratom of 5 December 2013 laying down basic safety standards for protection against the dangers arising from exposure to ionising radiation...
2017: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/28741133/african-and-caribbean-nurses-decisions-about-hiv-testing-a-mixed-methods-study
#8
Jean N Harrowing, Nancy Edwards, Solina Richter, Karin Minnie, Tania Rae
Nurses in Jamaica, Kenya, South Africa, and Uganda are at risk for occupational exposure to HIV. Little is known about the experiences and policy supports related to nurses having themselves tested for the virus. This article reports a mixed-methods study about contextual influences on nurses' decision-making about HIV testing. Individual and focus group interviews, as well as a questionnaire on workplace polices and quality assurance and a human resource management assessment tool provided data. Fear of a positive diagnosis and stigma and lack of confidentiality along with gaps in the policy environment contributed to indecision about testing...
July 24, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28740322/occupational-hearing-loss-from-non-gaussian-noise
#9
REVIEW
Alice H Suter
Noise levels are truly continuous in relatively few occupations, with some degree of intermittency the most common condition. The sound levels of intermittent noise are often referred to as non-Gaussian in that they are not normally distributed in the time domain. In some conditions, intermittent noise affects the ear differently from continuous noise, and it is this assumption that underlies the selection of the 5-dB exchange rate (ER). The scientific and professional communities have debated this assumption over recent decades...
August 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28738894/occupational-exposure-to-chlorinated-solvents-and-risk-of-head-and-neck-cancer-in-men-a-population-based-case-control-study-in-france
#10
Christine Barul, Aurore Fayossé, Matthieu Carton, Corinne Pilorget, Anne-Sophie Woronoff, Isabelle Stücker, Danièle Luce
BACKGROUND: Few epidemiological studies have investigated the link between occupational exposure to solvents and head and neck cancer risk, and available findings are sparse and inconsistent. The objective of this study was to examine the association between occupational exposure to chlorinated solvents and head and neck cancer risk. METHODS: We analyzed data from 4637 men (1857 cases and 2780 controls) included in a population-based case-control study, ICARE (France)...
July 24, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28738811/associations-of-genetic-variation-in-casp3-gene-with-noise-induced-hearing-loss-in-a-chinese-population-a-case-control-study
#11
Yinyin Wu, Juntao Ni, Mingjian Qi, Chengjian Cao, Yuxian Shao, Liangwen Xu, Haiyan Ma, Lei Yang
BACKGROUND: Noise-induced hearing loss (NIHL) is a complex disease caused by environmental and genetic risk factors. This study explored the relationship between the genetic variations in the CASP gene and the risk of developing NIHL among Chinese workers exposed to occupational noise. METHODS: A case-control study of 272 NIHL workers and 272 normal-hearing workers matched for age, sex and years of noise exposure was conducted. Fifteen single-nucleotide polymorphisms (SNP) in the CASP1, CASP3, CASP4, CASP5, CASP6, CASP8, CASP9, CASP10 and CASP14 genes were genotyped using the polymerase chain reaction-ligase detection reaction method...
July 24, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28738262/systematic-review-of-community-health-impacts-of-mountaintop-removal-mining
#12
REVIEW
Abee L Boyles, Robyn B Blain, Johanna R Rochester, Raghavendhran Avanasi, Susan B Goldhaber, Sofie McComb, Stephanie D Holmgren, Scott A Masten, Kristina A Thayer
BACKGROUND: The objective of this evaluation is to understand the human health impacts of mountaintop removal (MTR) mining, the major method of coal mining in and around Central Appalachia. MTR mining impacts the air, water, and soil and raises concerns about potential adverse health effects in neighboring communities; exposures associated with MTR mining include particulate matter (PM), polycyclic aromatic hydrocarbons (PAHs), metals, hydrogen sulfide, and other recognized harmful substances...
July 21, 2017: Environment International
https://www.readbyqxmd.com/read/28738185/mother-and-child-characteristics-at-birth-and-early-age-leukemia-a-case-cohort-population-based-study-in-brazil
#13
Rejane de Souza Reis, Neimar de Paula Silva, Marceli de Oliveira Santos, Julio Fernando Pinto Oliveira, Luiz Claudio Santos Thuler, Beatriz de Camargo, Maria S Pombo-de-Oliveira
OBJECTIVE: The population-based cancer registries (PBCR) and the Information System on Live Births in Brazil (Sistema de Informações sobre Nascidos Vivos [SINASC]) have information that enables the test for risk factors associated with leukemia at an early age. The aim of this study was to identify maternal and birth characteristics associated with early-age acute leukemia (EAL) in Brazil. METHODS: A case-cohort study was performed using secondary dataset information of PBCR and SINASC...
July 21, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28736450/screening-survey-of-ocular-nasal-respiratory-and-skin-symptoms-in-manicurists-in-poland
#14
Marta Kieć-Świerczyńska, Dominika Świerczyńska-Machura, Dorota Chomiczewska-Skóra, Beata Kręcisz, Jolanta Walusiak-Skorupa
OBJECTIVES: Manicurists are exposed to various chemicals in nail and skin care products and may develop ocular, nasal, respiratory or skin adverse reactions to them. To investigate the occurrence of ocular, nasal, respiratory and skin problems among manicurists and to identify their causal factors, particularly allergic etiology and occupational origin. MATERIAL AND METHODS: Manicurists employed in beauty salons in the central region of Poland were invited to fill in the questionnaire and undergo medical examination, skin prick tests with common aeroallergens, patch tests with European Baseline Series and (Meth)Acrylates Series-Nails and spirometry...
July 12, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28734852/azodicarbonamide-adca-a-reconsideration-of-classification-as-a-respiratory-sensitiser
#15
Josje Arts, Ian Kimber
Azodicarbonamide (ADCA) is widely used by industry in the manufacture of a variety of products. ADCA has been classified as a respiratory allergen, and the purpose of this article was to consider whether this classification is appropriate based upon the available data. Here both clinical experience and relevant experimental data have been reviewed. Although there have been reports of an association between workplace exposure to ADCA and symptoms of respiratory allergy and occupational asthma, the evidence is less than persuasive, with in many instances a lack of properly controlled and executed diagnostic procedures...
July 19, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28733964/the-global-burden-of-occupational-disease
#16
REVIEW
Lesley Rushton
PURPOSE OF REVIEW: Burden of occupational disease estimation contributes to understanding of both magnitude and relative importance of different occupational hazards and provides essential information for targeting risk reduction. This review summarises recent key findings and discusses their impact on occupational regulation and practice. RECENT FINDINGS: New methods have been developed to estimate burden of occupational disease that take account of the latency of many chronic diseases and allow for exposure trends and workforce turnover...
July 21, 2017: Current Environmental Health Reports
https://www.readbyqxmd.com/read/28732841/cobalt-related-interstitial-lung-disease
#17
REVIEW
Traci N Adams, Yasmeen M Butt, Kiran Batra, Craig S Glazer
Cobalt exposure in the hard metal and bonded diamond tool industry is a well-established cause of ILD. The primary theories regarding the underlying mechanism of cobalt related ILD include an immunologic mechanism and an oxidant injury mechanism. Cobalt related ILD may present in subacute and chronic forms and often has associated upper respiratory symptoms. The evaluation begins with a thorough occupational history and includes PFTs, HRCT, and bronchoalveolar lavage. HRCT findings are nonspecific and may resemble NSIP, UIP, sarcoidosis, or HP...
August 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28732839/exacerbations-and-duration-of-smoking-abstinence-are-associated-with-the-annual-loss-of-fev1-in-individuals-with-pizz-alpha-1-antitrypsin-deficiency
#18
Sebastian Fähndrich, Nikolas Bernhard, Philipp M Lepper, Claus Vogelmeier, Martina Seibert, Stefan Wagenpfeil, Robert Bals
BACKGROUND: Alpha-1-antitrypsin deficiency (AATD) is a genetic disorder that is associated with a higher risk of chronic obstructive pulmonary disease (COPD) and emphysema. The annual declines in lung function (FEV1) and transfer factor of the lung for carbon monoxide (TLCO) predict all-cause mortality. MATERIAL AND METHODS: We investigated the longitudinal follow-up data over 11 years (mean follow-up period of 4.89 years) from the German AATD registry and analyzed the relationship between annual loss of FEV1 and TLCO and sex, age, body mass index (BMI), nicotine consumption, occupational dust exposure, St...
August 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28732740/exposure-survey-of-trends-in-occupational-practice-expo-s-t-o-p-2015-a-national-survey-of-sharps-injuries-and-mucocutaneous-blood-exposures-among-health-care-workers-in-us-hospitals
#19
T Grimmond, L Good
BACKGROUND: National blood exposure (BE) surveys are valuable to health care facilities striving to reduce percutaneous sharps injuries (SIs) or mucocutaneous (MC) exposures among their health care workers (HCWs). In the Exposure Survey of Trends in Occupational Practice (EXPO-S.T.O.P.) 2015 we surveyed hospital BE incidence among members of the Association of Occupational Health Professionals in Healthcare. METHODS: A 23-item electronic survey requested 2015 data on total SI and MC; SI in nurses, doctors, and surgery; staffed beds; teaching status; full time equivalent staff (FTE), nurse FTE, average daily census (ADC), and adjusted patient days (APD)...
July 18, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28732380/characteristics-survival-and-risk-factors-of-chinese-young-lung-cancer-patients-the-experience-from-two-institutions
#20
Jianjie Li, Fan Yang, Xiao Li, Min Zhang, Ruozi Fu, Xiaodan Yin, Jun Wang
Limited data is available regarding lung cancer in Chinese young adults. This study was aimed to determine the characteristics, survival, and prognostic factors of young lung cancer patients in China. We reviewed demographic and clinical data, and survival information of 420 young patients (20-45 years old) diagnosed with lung cancer in two Chinese hospitals between 2000 and 2013. The results showed that lung cancer occurred more frequently (70%) and affected more males than females (43.8% vs 26.7%) in patients older than 36; whereas, more females were affected under age 35 (16...
July 12, 2017: Oncotarget
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