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occupational exposure

Tine Gjedde Sommer, Susanne Wulff Svendsen, Poul Frost
OBJECTIVE: The aim of this study was to examine if combined pain (pain in the upper and lower body), high occupational mechanical exposures, and job strain predict sickness absence and permanent work disability, particularly if co-occurring. METHODS: This longitudinal study was based on the musculoskeletal research database at the Danish Ramazzini Centre. We linked baseline information from 2001-2004 on musculoskeletal pain, job titles, and covariates with register information on sickness absence and permanent work disability...
October 13, 2016: Scandinavian Journal of Work, Environment & Health
John C Flunker, Jessica Miller Clouser, David Mannino, Jennifer Swanberg
BACKGROUND: Latino thoroughbred workers may be at risk for developing abnormal pulmonary function related to occupational exposures. METHODS: Eighty worker participants were recruited via community-based purposive sampling. Questionnaires and spirometry tests were administered by trained lay health promoters. Demographic and occupational factors were assessed for associations with respiratory outcomes via multivariable logistic regression. RESULTS: Twenty-seven percent of participants exhibited abnormal pulmonary function (primarily restrictive), 79% reported any respiratory symptoms, and 94% infrequently used dust masks...
October 24, 2016: American Journal of Industrial Medicine
Xiaoshu Lü, Esa-Pekka Takala, Esko Toppila, Ykä Marjanen, Leena Kaila-Kangas, Tao Lu
Exposure to whole-body vibration (WBV) presents an occupational health risk and several safety standards obligate to measure WBV. The high cost of direct measurements in large epidemiological studies raises the question of the optimal sampling for estimating WBV exposures given by a large variation of exposure levels in real worksites. This paper presents a new approach to address this problem. A daily exposure to WBV was recorded for 9 to 24 days among 48 all-terrain vehicle drivers. Four datasets based on root mean squared recordings were obtained from the measurement...
October 25, 2016: Ergonomics
Yunjeong Heo, Hosun Chun, Seonghoon Kang, Wonjin Lee, Taewon Jang, Jongtae Park
BACKGROUND: With increasing use of medical radiologic procedures, wearing proper protector should be emphasized to reduce occupational radiation exposures. This research describes the rates of lead apron wearing for radiation protection and assessed occupational factors related to wearing rates for various types of healthcare professionals. METHODS: We conducted a self-administered questionnaire survey through a website, on-site visits, fax, and mail. Of the 13,489 participants, 8858 workers who could not completely separate themselves from radiological procedure areas...
2016: Annals of Occupational and Environmental Medicine
Laura Kurth, Brent Doney, Sheila Weinmann
OBJECTIVES: To compare the occupational exposure levels assigned by our National Institute for Occupational Safety and Health chronic obstructive pulmonary disease-specific job exposure matrix (NIOSH COPD JEM) and by expert evaluation of detailed occupational information for various jobs held by members of an integrated health plan in the Northwest USA. METHODS: We analysed data from a prior study examining COPD and occupational exposures. Jobs were assigned exposure levels using 2 methods: (1) the COPD JEM and (2) expert evaluation...
October 24, 2016: Occupational and Environmental Medicine
Anca Radauceanu, Michel Grzebyk, Jean-Louis Edme, Nathalie Chérot-Kornobis, Davy Rousset, Mathieu Dziurla, Virginie De Broucker, Guy Hedelin, Annie Sobaszek, Sébastien Hulo
OBJECTIVE: To analyze the effects of occupational exposure to poorly soluble forms of beryllium (Be) on biomarkers of pulmonary inflammation using exhaled breath condensate (EBC) in workers employed in machining industries. METHODS: Twenty machining operators were compared to 16 controls. The individual exposure to Be was assessed from the work history with several indices of exposure calculated on the basis of task-exposures matrices developed for each plant using historical air measurements...
October 21, 2016: Toxicology Letters
Flavio Raponi, Lisa Bauleo, Carla Ancona, Francesco Forastiere, Enrico Paci, Daniela Pigini, Giovanna Tranfo
CONTEXT: several urinary PAHs metabolites can be detected by HPLC-MS/MS for individual exposure assessment. OBJECTIVE: quantitation of urinary metabolites of four PAHs, selected on the basis of their significance, with reduced costs and high sensitivity. MATERIALS AND METHODS: HPLC-MS/MS was used and pure standards and isotope labelled internal analogues of the analytes. Two hundred samples were tested after enzymatic hydrolysis. RESULTS: accuracy was higher than 90% and variability lower than 19%; LODs permit to measure 1-hydroxypyrene, 1 and 2-hydroxynaphthalene in all subjects, 6-hydroxynitropyrene in the 65% and 3-hydroxybenzo[a]pyrene in the 70%...
October 24, 2016: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
B Estors Sastre, P Bragagnini Rodríguez, R Fernández Atuan, R Delgado Alvira, M A Rihuete Heras, J Gracia Romero
AIM OF THE STUDY: To investigate the association between endocrine disrupting chemicals (EDC) exposure and other paternal factors in the etiology of hipospadias and cryptorchidism. METHODS: A case-control study. Cases were infants between 0 and 6 years of age diagnosed with hypospadias or cryptorchidism in our pediatric urology and general pediatric surgery services during a period of 6 months, and controls were infants with the same range of age attending the same services without any urological problem...
April 20, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
Juan José Palacios, Yurena Navarro, Beatriz Romero, Ana Penedo, Ángela Menéndez González, M Dolores Pérez Hernández, Ana Fernández-Verdugo, Francisca Copano, Aurora Torreblanca, Emilio Bouza, Lucas Domínguez, Lucía de Juan, Darío García-de-Viedma
Human Mycobacterium bovis infections are considered to be due to reactivations, when involve elderly people, or to recent transmissions, when exposure is occupational. We determined the cause of M. bovis infections by genotyping M. bovis isolates in a population-based study integrating human and animal databases. Among the 1,586 tuberculosis (TB) cases in Asturias, Northern Spain (1,080,000 inhabitants), 1,567 corresponded to M. tuberculosis and 19 to M. bovis. The number of human isolates sharing genotype with cattle isolates was higher than expected (47%) for a setting with low prevalence of bovine TB and efficient control programs in cattle...
November 15, 2016: Veterinary Microbiology
Anja Stajnko, Ingrid Falnoga, Janja Snoj Tratnik, Darja Mazej, Marta Jagodic, Mladen Krsnik, Alfred B Kobal, Marija Prezelj, Lijana Kononenko, Milena Horvat
BACKGROUND: Urine cadmium (Cd) and renal function biomarkers, mostly analysed in urine spot samples, are well established biomarkers of occupational exposure. Their use and associations at low environmental level are common, but have recently been questioned, particularly in terms of physiological variability and normalisation bias in the case of urine spot samples. AIM: To determine the appropriateness of spot urine and/or blood Cd exposure biomarkers and their relationships with renal function biomarkers at low levels of exposure...
October 19, 2016: Environmental Research
J Teixeira, J R Mesquita, S S Pereira, R M S Oliveira, J Abreu-Silva, A Rodrigues, M Myrmel, K Stene-Johansen, J Øverbø, G Gonçalves, M S J Nascimento
The concept of zoonotic hepatitis E in industrialized countries has emerged with the discovery of swine strains of hepatitis E virus (HEV) genotype 3, closely related to human HEV. Different routes of zoonotic HEV transmission have been recognized, including contact with infected pigs. Workers occupationally exposed to swine (WOES) have been considered a risk group for HEV infection, but contradictory results have been reported. In the present study, we searched for anti-HEV IgG in WOES (butchers, slaughterhouse workers, veterinarians and pig farmers; n = 114) and in the general population (n = 804) in order to investigate the potential occupational risk of zoonotic HEV infection in this work group...
October 21, 2016: Medical Microbiology and Immunology
D Gallart-Mateu, S Armenta, M de la Guardia
The use of ion mobility spectrometry (IMS) has been evaluated as analytical methodology to detect and evaluate the occupational exposure to pesticides. The developed IMS methodology was used, in positive and negative modes, to determine the presence of pesticides in air and to evaluate possible inhalation exposures of workers and users based on active sampling on Teflon membranes and direct thermal desorption IMS. The negative IMS mode was used to determine bensulfuron, clorpyrifos, diniconazole, diuron, flutolanil and imidacloprid, while the positive mode was employed to evaluate formetanate, metalaxyl, metamitrone, metribuzin, paclobutrazol and pirimicarb...
December 1, 2016: Talanta
Jean-François Sauvé, Jérôme Lavoué, Marie-Élise Parent
BACKGROUND: Age, family history and ancestry are the only recognized risk factors for prostate cancer (PCa) but a role for environmental factors is suspected. Due to the lack of knowledge on the etiological factors for PCa, studies that are both hypothesis-generating and confirmatory are still needed. This study explores relationships between employment, by occupation and industry, and PCa risk. METHODS: Cases were 1937 men aged ≤75 years with incident PCa diagnosed across Montreal French hospitals in 2005-2009...
October 21, 2016: Environmental Health: a Global Access Science Source
Nina Holland
Environmental research and public health in the 21st century face serious challenges such as increased air pollution and global warming, widespread use of potentially harmful chemicals including pesticides, plasticizers, and other endocrine disruptors, and radical changes in nutrition and lifestyle typical of modern societies. In particular, exposure to environmental and occupational toxicants may contribute to the occurrence of adverse birth outcomes, neurodevelopmental deficits, and increased risk of cancer and other multifactorial diseases such as diabetes and asthma...
October 21, 2016: Reviews on Environmental Health
Surya Narayan Pradhan, Aleena Das, Ramovatar Meena, Ranjan Kumar Nanda, Paulraj Rajamani
Occupational exposure to air pollution induces oxidative stress and prolonged exposure increases susceptibility to cardiovascular and respiratory diseases in several working groups. Biofluid of these subjects may reflect perturbed metabolic phenotypes. In this study we carried out a comparative molecular profiling study using parallel biofluids collected from subjects (n = 85) belonging to auto rickshaw drivers (ARD), traffic cops (TC) and office workers (OW). Higher levels of oxidative stress and inflammation markers in serum of ARD subjects were observed as compared to OW and TC...
October 21, 2016: Scientific Reports
Takayuki Koga, Pei-Li Yao, Maryam Goudarzi, Iain A Murray, Gayathri Balandaram, Frank J Gonzalez, Gary H Perdew, Albert J Fornace, Jeffrey M Peters
Alcoholic liver disease is a pathological condition caused by over-consumption of alcohol. Due to the high morbidity and mortality associated with this disease, there remains a need to elucidate the molecular mechanisms underlying its etiology and to develop new treatments. Since peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) modulates ethanol-induced hepatic effects, the present study examined alterations in gene expression that may contribute to this disease. Chronic ethanol treatment causes increased hepatic CYP2B10 expression in Pparβ/δ+/+ mice, but not in Pparβ/δ-/- mice...
October 20, 2016: Journal of Biological Chemistry
John J Guardiola, Juliane I Beier, K Cameron Falkner, Benjamin Wheeler, Craig James McClain, Matt Cave
BACKGROUND: Occupational vinyl chloride (VC) exposures have been associated with toxicant-associated steatohepatitis and liver cancer. Metabolomics has been used to clarify mode of action in drug-induced liver injury but has not been performed following VC exposures. METHODS: Plasma samples from 17 highly exposed VC workers without liver cancer and 27 unexposed healthy volunteers were obtained for metabolite extraction and GC/MS and LC/MS(2) analysis. Following ion identification/quantification, Ingenuity pathway analysis was performed...
October 17, 2016: Toxicology and Applied Pharmacology
J W Zhang, Q Zeng, L Zhao, M Zhang, L Zhang, Q Gu
Objective: To investigate the association between parental environmental risk factors exposure and the risk for childhood acute lymphoblastic leukemia (ALL). Methods: A total of 179 ALL children cases were selected in Tianjin Blood Disease Hospital and 136 healthy children matched by age, gender and living place were selected in 2015 for a case control study. The data were analyzed with univariate and multivariate non conditional logistic regression models. Results: The results of multivariate logistic regression analysis indicated that sex, history of abortion, exposure in a smoking environment during pregnancy, catching a cold, taking antipyretic analgesics, maternal exposure to air purifying agent, father' s occupational exposure to petroleum products and home decoration during pregnancy were associated with the risk of childhood ALL (P<0...
October 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
Berrin Serdar, Stephen Brindley, Greg Dooley, John Volckens, Elizabeth Juarez-Colunga, Ryan Gan
BACKGROUND: Roofers are at increased risk for various malignancies and their occupational exposures to polycyclic aromatic hydrocarbons (PAHs) have been considered as important risk factors. The overall goal of this project was to investigate the usefulness of phosphorylated histone H2AX (γH2AX) as a short-term biomarker of DNA damage among roofers. METHODS: Blood, urine, and dermal wipe samples were collected from 20 roofers who work with hot asphalt before and after 6 h of work on Monday and Thursday of the same week (4 sampling periods)...
October 20, 2016: Environmental Health: a Global Access Science Source
Gurmail Singh Paddan
INTRODUCTION: Measurements were made of the sound pressure levels on a military ship HMS Grimsby during firing of a Heavy Machine Gun (HMG) mounted on the starboard bridge wing. The measurement positions comprised three locations on the ship's bridge (the wheelhouse) and one location on the starboard bridge wing. Equipment and Procedure: The three locations on the bridge were the starboard door, centre and port door. A total of 255 burst firings were measured during the survey comprising 850 rounds with each burst encompassing from 1 to 10 rounds...
September 2016: Noise & Health
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