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https://www.readbyqxmd.com/read/29031419/impact-of-surgical-waiting-time-on-survival-in-patients-with-upper-tract-urothelial-carcinoma-a-national-cancer-database-study
#1
Leilei Xia, Benjamin L Taylor, Jose E Pulido, Thomas J Guzzo
PURPOSE: To evaluate the impact of surgical waiting time (SWT) on the survival outcome in patients with upper tract urothelial carcinoma (UTUC). MATERIALS AND METHODS: We identified patients with nonmetastatic UTUC who underwent radical nephroureterectomy (RNU) between 2004 and 2013 in the National Cancer Database. The association between SWT and overall survival (OS) was evaluated using Cox proportional hazards regression. SWT was categorized into 6 groups: SWT ≤ 7 days, SWT 8 to 30 days, SWT 31 to 60 days, SWT 61 to 90 days, SWT 91 to 120 days, and SWT 121 to 180 days...
October 11, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28872360/cardiorespiratory-fitness-and-walking-endurance-improvements-after-12-months-of-an-individualised-home-and-community-based-exercise-programme-for-people-after-stroke
#2
Ashlee Dunn, Dianne L Marsden, Daniel Barker, Paulette Van Vliet, Neil J Spratt, Robin Callister
OBJECTIVE: To evaluate the immediate and longer-term effects of an individually tailored, home- and community-based exercise programme with ongoing remote support in people with stroke on cardiorespiratory fitness (CRF), ambulation and health-related quality of life (HRQoL). METHODS: Twenty people 5.3 ± 3.5 months post stroke completed the 12-week HowFITSS? exercise programme aimed at increasing CRF and daily physical activity. Support was provided by phone and email, which decreased in frequency over time...
September 5, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28868151/motion-artefact-removals-for-wearable-ecg-using-stationary-wavelet-transform
#3
Shuto Nagai, Daisuke Anzai, Jianqing Wang
Wearable Electrocardiogram (ECG) is attracting much attention in daily healthcare applications. From the viewpoint of long-term use, it is desired that the electrodes are non-contact with the human body. In this study, the authors propose an algorithm using the stationary wavelet transform (SWT) to remove motion artefact superimposed on ECG signal when using non-contact capacitively coupling electrodes. The authors evaluate the effect on motion artefact removal of this algorithm by applying it to various ECG signals with motion artefacts superimposed...
August 2017: Healthcare Technology Letters
https://www.readbyqxmd.com/read/28858112/prescription-of-chinese-herbal-products-is-associated-with-a-decreased-risk-of-invasive-breast-cancer
#4
Yueh-Ting Tsai, Jung-Nien Lai, Pei-Chia Lo, Chin-Nu Chen, Jaung-Geng Lin
The finding of a decrease in endometrial cancer incidence among breast cancer survivors following the use of Chinese herbal products (CHPs) has led to speculation that CHPs might play a role in breast cancer prevention.This study provides an overview of breast cancer incidence, comparing CHP users with those who do not use traditional Chinese medicine (TCM), referred to as non-TCM users. The results can provide information to clinicians for counseling women about the preventive use of TCM.A total of 184,386 women (20-79 years of age) were recruited from a nationwide 1-million-person representative sample of those covered by National Health Insurance in Taiwan and were followed from 1999 to 2012...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28798829/does-surgical-delay-for-radical-prostatectomy-affect-patient-pathological-outcome-a-retrospective-analysis-from-a-canadian-cohort
#5
Marc Zanaty, Mansour Alnazari, Kelsey Lawson, Mounsif Azizi, Emad Rajih, Abdullah Alenizi, Pierre-Alain Hueber, Malek Meskawi, Cedric Lebacle, Thierry Lebeau, Serge Benayoun, Pierre I Karakiewicz, Assaad El-Hakim, Kevin C Zorn
INTRODUCTION: We sought to assess the impact of surgical wait time (SWT) to robot-assisted radical prostatectomy (RARP) on final pathological outcome. METHODS: A retrospective review of RARP patient records operated between 2006 and 2015 was conducted. SWT was defined as period from prostate biopsy to surgery. Primary outcome was the impact on postoperative Cancer of the Prostate Risk Assessment (CAPRA-S) score. Patients were stratified according to D'Amico risk categories...
August 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28782612/impact-of-the-removal-of-n-terminal-non-structured-amino-acids-on-activity-and-stability-of-xylanases-from-orpinomyces-sp-pc-2
#6
Rafaela Zandonade Ventorim, Tiago Antônio de Oliveira Mendes, Larissa Mattos Trevizano, Ana Maria Dos Santos Camargos, Valéria Monteze Guimarães
Xylanases catalyze the random hydrolysis of xylan backbone from plant biomass and thus, they have application in the production of biofuels, Kraft pulps biobleaching and feed industry. Here, xylanases derived from Orpinomyces sp. PC-2 were engineered guided by molecular dynamics methods to obtain more thermostable enzymes. Based on these models, 27 amino acid residues from the N-terminal were predicted to reduce protein stability and the impact of this removal was validated to two enzyme constructs: small xylanase Wild-Type (SWT) obtained from Wild-Type xylanase (WT) and small xylanase Mutant (SM2) generated from M2 mutant xylanase (V135A, A226T)...
August 3, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28772873/a-new-energy-critical-plane-damage-parameter-for-multiaxial-fatigue-life-prediction-of-turbine-blades
#7
Zheng-Yong Yu, Shun-Peng Zhu, Qiang Liu, Yunhan Liu
As one of fracture critical components of an aircraft engine, accurate life prediction of a turbine blade to disk attachment is significant for ensuring the engine structural integrity and reliability. Fatigue failure of a turbine blade is often caused under multiaxial cyclic loadings at high temperatures. In this paper, considering different failure types, a new energy-critical plane damage parameter is proposed for multiaxial fatigue life prediction, and no extra fitted material constants will be needed for practical applications...
May 8, 2017: Materials
https://www.readbyqxmd.com/read/28762588/an-investigation-of-shock-wave-therapy-and-low-intensity-pulsed-ultrasound-on-fracture-healing-under-reduced-loading-conditions-in-an-ovine-model
#8
Benjamin C Gadomski, Kirk C McGilvray, Jeremiah T Easley, Ross H Palmer, Jian Jiao, Xiaofei Li, Yi-Xian Qin, Christian M Puttlitz
The use of shock wave therapy (SWT) and low-intensity pulsed ultrasound (LIPUS) as countermeasures to the inhibited fracture healing experienced during mechanical unloading was investigated by administering treatment to the fracture sites of mature, female, Rambouillet Columbian ewes exposed to partial mechanical unloading or full gravitational loading. The amount of fracture healing experienced by the treatment groups was compared to controls in which identical surgical and testing protocols were administered except for SWT or LIPUS treatment...
August 1, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28761028/variation-in-access-to-pediatric-surgical-care-among-coexisting-public-and-private-providers-inguinal-hernia-as-a-model
#9
Ayman Al-Jazaeri, Lama Alshwairikh, Manar A Aljebreen, Nourah AlSwaidan, Tarfah Al-Obaidan, Abdulrahman Alzahem
BACKGROUND: Faced with growing healthcare demand, the Saudi government is increasingly relying on privatization as a tool to improve patient access to care. Variation in children's access to surgical care between public (PB) and private providers (PV) has not been previously analyzed. OBJECTIVES: To compare access to pediatric surgical services between two coexisting PB and PV. DESIGN: Retrospective comparative study. SETTINGS: A major teaching hospital and the largest PV group in Saudi Arabia...
July 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28724418/improved-recovery-of-regional-left-ventricular-function-after-pci-of-chronic-total-occlusion-in-stemi-patients-a-cardiovascular-magnetic-resonance-study-of-the-randomized-controlled-explore-trial
#10
Joëlle Elias, Ivo M van Dongen, Loes P Hoebers, Dagmar M Ouweneel, Bimmer E P M Claessen, Truls Råmunddal, Peep Laanmets, Erlend Eriksen, René J van der Schaaf, Dan Ioanes, Robin Nijveldt, Jan G Tijssen, Alexander Hirsch, José P S Henriques
BACKGROUND: The Evaluating Xience and left ventricular function in PCI on occlusiOns afteR STEMI (EXPLORE) trial did not show a significant benefit of percutaneous coronary intervention (PCI) of the concurrent chronic total occlusion (CTO) in ST-segment elevation myocardial infarction (STEMI) patients on global left ventricular (LV) systolic function. However a possible treatment effect will be most pronounced in the CTO territory. Therefore, we aimed to study the effect of CTO PCI compared to no-CTO PCI on the recovery of regional LV function, particularly in the CTO territory...
July 19, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28700634/differential-modulation-of-the-lactisole-sweet-water-taste-by-sweeteners
#11
RANDOMIZED CONTROLLED TRIAL
Cynthia Alvarado, Danielle Nachtigal, Jay P Slack, Barry G Green
Pre-exposure to taste stimuli and certain chemicals can cause water to have a taste. Here we studied further the 'sweet water taste' (SWT) perceived after exposure to the sweet taste inhibitor lactisole. Experiment 1 investigated an incidental observation that presenting lactisole in mixture with sucrose reduced the intensity of the SWT. The results confirmed this observation and also showed that rinsing with sucrose after lactisole could completely eliminate the SWT. The generalizability of these findings was investigated in experiment 2 by presenting 5 additional sweeteners before, during, or after exposure to lactisole...
2017: PloS One
https://www.readbyqxmd.com/read/28670161/left-ventricular-functional-parameters-and-geometric-patterns-in-korean-adults-on-coronary-ct-angiography-with-a-320-detector-row-ct-scanner
#12
Eun-Ju Kang, Ki-Nam Lee, Won Jin Choi, Young-Dae Kim, Kyung Min Shin, Jae-Kwang Lim, Jongmin Lee
OBJECTIVE: To assess the normal reference values of left ventricle (LV) functional parameters in Korean adults on coronary CT angiography (CCTA) with a 320-detector-row CT scanner, and to analyze sex-related differences and correlations with various clinical characteristics. MATERIALS AND METHODS: This study retrospectively enrolled 172 subjects (107 men and 65 women; age, 58 ± 10.9 years; body surface area [BSA], 1.75 ± 0.2 m(2)) who underwent CCTA without any prior history of cardiac disease...
July 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28556355/bias-and-inference-from-misspecified-mixed-effect-models-in-stepped-wedge-trial-analysis
#13
Jennifer A Thompson, Katherine L Fielding, Calum Davey, Alexander M Aiken, James R Hargreaves, Richard J Hayes
Many stepped wedge trials (SWTs) are analysed by using a mixed-effect model with a random intercept and fixed effects for the intervention and time periods (referred to here as the standard model). However, it is not known whether this model is robust to misspecification. We simulated SWTs with three groups of clusters and two time periods; one group received the intervention during the first period and two groups in the second period. We simulated period and intervention effects that were either common-to-all or varied-between clusters...
October 15, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28514395/-impact-of-shock-wave-therapy-on-the-clinical-and-functional-status-of-patients-with-coronary-heart-disease
#14
S T Matskeplishvili, B M Borbodoeva, E U Asymbekova, A Z Rakhimov, N K Akhmedyarova, K B Kataeva, Yu I Buziashvili
AIM: To study of the impact of shock-wave therapy (SWT) on the functional status of patients with coronary heart disease (CHD). SUBJECTS AND METHODS: Thirty-four CHD patients (including 33 men) with left ventricular (LV) asynergic segments, as evidenced by echocardiography (EchoCG), were examined. Their mean age was 60.1±1.76 years. All the patients received a SWT cycle according to the standard scheme. The patient examination protocol involved EchoCG, dobutamine EchoCG, treadmill exercise EchoCG, and tissue Doppler EchoCG, which were performed at baseline, immediately and one month after the end of a SWT cycle...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28449487/performance-in-the-shuttle-walk-test-is-associated-with-cardiopulmonary-complications-after-lung-resections
#15
Joseph Fennelly, Lauren Potter, Cecilia Pompili, Alessandro Brunelli
BACKGROUND: The current functional guidelines recommend the shuttle walk test (SWT) as an initial screening tool to identify candidates for lung resection without requiring cardiopulmonary exercise testing. This study aims to: (I) assess the use of the SWT in predicting postoperative cardiopulmonary complications; and (II) determine whether the recommended 400 m cut-off is an appropriate distance. METHODS: We retrospectively analysed 101 patients that had performed a SWT prior to surgery...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28421305/the-utility-of-global-longitudinal-strain-in-the-identification-of-prior-myocardial-infarction-in-patients-with-preserved-left-ventricular-ejection-fraction
#16
Graham J Fent, Pankaj Garg, James R J Foley, Laura E Dobson, Tarique A Musa, Bara Erhayiem, John P Greenwood, Sven Plein, Peter P Swoboda
Prior myocardial infarction (MI) is associated with increased mortality and is prevalent in certain high risk patient groups. Electrocardiogram may be used in diagnosis, however, sensitivity is limited, thus non-invasive imaging techniques may improve diagnosis. We investigated whether global longitudinal strain (GLS) and longitudinal strain parameters are reduced in patients with prior MI but preserved left ventricular ejection fraction (LVEF). The study included 40 clinical patients with prior MI occurring >3 months previously (defined as subendocardial hyperenhancement on late Gadolinium enhancement imaging) with LVEF ≥ 55% and 40 controls matched for age and LVEF...
April 18, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28391581/contribution-of-mitral-valve-leaflet-length-and-septal-wall-thickness-to-outflow-tract-obstruction-in-patients-with-hypertrophic-cardiomyopathy
#17
Kareem Morant, Yoko Mikami, Immaculate Nevis, David McCarty, John Stirrat, David Scholl, Martin Rajchl, Peter Giannoccaro, Louis Kolman, Bobby Heydari, Carmen Lydell, Andrew Howarth, Andrew Grant, James A White
We sought to examine whether elongation of the mitral valve leaflets in patients with hypertrophic cardiomyopathy (HCM) is synergistic to septal wall thickness (SWT) in the development of left ventricular outflow tract obstruction (LVOTO). HCM is a common genetic cardiac disease characterized by asymmetric septal hypertrophy and predisposition towards LVOTO. It has been reported that elongation of the mitral valve leaflets may be a primary phenotypic feature and contribute to LVOTO. However, the relative contribution of this finding versus SWT has not been studied...
August 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28335476/inhibition-of-neoplastic-transformation-and-chemically-induced-skin-hyperplasia-in-mice-by-traditional-chinese-medicinal-formula-si-wu-tang
#18
Mandy M Liu, Kevin M Huang, Steven Yeung, Andy Chang, Suhui Zhang, Nan Mei, Cyrus Parsa, Robert Orlando, Ying Huang
Exploring traditional medicines may lead to the development of low-cost and non-toxic cancer preventive agents. Si-Wu-Tang (SWT), comprising the combination of four herbs, Rehmanniae, Angelica, Chuanxiong, and Paeoniae, is one of the most popular traditional Chinese medicines for women's diseases. In our previous studies, the antioxidant Nrf2 pathways were strongly induced by SWT in vitro and in vivo. Since Nrf2 activation has been associated with anticarcinogenic effects, the purpose of this study is to evaluate SWT's activity of cancer prevention...
March 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28268456/emotion-classification-using-single-channel-scalp-eeg-recording
#19
Amir Jalilifard, Ednaldo Brigante Pizzolato, Md Kafiul Islam
Several studies have found evidence for corticolimbic Theta electroencephalographic (EEG) oscillation in the neural processing of visual stimuli perceived as fear or threatening scene. Recent studies showed that neural oscillations' patterns in Theta, Alpha, Beta and Gamma sub-bands play a main role in brain's emotional processing. The main goal of this study is to classify two different emotional states by means of EEG data recorded through a single-electrode EEG headset. Nineteen young subjects participated in an EEG experiment while watching a video clip that evoked three emotional states: neutral, relaxation and scary...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28261267/a-novel-multilevel-svd-method-to-improve-multistep-ahead-forecasting-in-traffic-accidents-domain
#20
Lida Barba, Nibaldo Rodríguez
Here is proposed a novel method for decomposing a nonstationary time series in components of low and high frequency. The method is based on Multilevel Singular Value Decomposition (MSVD) of a Hankel matrix. The decomposition is used to improve the forecasting accuracy of Multiple Input Multiple Output (MIMO) linear and nonlinear models. Three time series coming from traffic accidents domain are used. They represent the number of persons with injuries in traffic accidents of Santiago, Chile. The data were continuously collected by the Chilean Police and were weekly sampled from 2000:1 to 2014:12...
2017: Computational Intelligence and Neuroscience
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