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https://www.readbyqxmd.com/read/29601228/evaluation-of-three-measures-of-cardiorespiratory-fitness-in-independently-ambulant-stroke-survivors
#1
Ashlee Dunn, Dianne L Marsden, Daniel Barker, Paulette van Vliet, Neil J Spratt, Robin Callister
Measuring cardiorespiratory fitness (CRF) in the stroke population is challenging. Currently, the recommended method is a graded exercise test (GXT) on an ergometer such as a treadmill or cycle, which may not always be possible. We investigated whether walking tests such as the six-minute walk test (6MWT) and the shuttle walk test (SWT) may be appropriate indicators of CRF in the stroke population. Twenty-three independently ambulant stroke survivors (11 men, age 61.5 ± 18.4 years) within one-year post stroke performed the 6MWT, SWT, and cycle GXT, during which peak oxygen consumption (VO2peak ) and heart rate (HRpeak ) were recorded...
March 30, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29560450/integration-of-stationary-wavelet-transform-on-a-dynamic-partial-reconfiguration-for-recognition-of-pre-ictal-gamma-oscillations
#2
N Jmail, M Zaghdoud, A Hadriche, T Frikha, C Ben Amar, C Bénar
To define the neural networks responsible of an epileptic seizure, it is useful to perform advanced signal processing techniques. In this context, electrophysiological signals present three types of waves: oscillations, spikes, and a mixture of both. Recent studies show that spikes and oscillations should be separated properly in order to define the accurate neural connectivity during the pre-ictal, seizure and inter-ictal states. Retrieving oscillatory activity is a sensitive task due to the frequency overlap between oscillations and transient activities...
February 2018: Heliyon
https://www.readbyqxmd.com/read/29496161/effects-of-bioactive-constituents-in-the-traditional-chinese-medicinal-formula-si-wu-tang-on-nrf2-signaling-and-neoplastic-cellular-transformation
#3
Mandy M Liu, Kevin M Huang, Li Qian, Payal Chatterjee, Suhui Zhang, Rui Li, Su Zhou, Zhijun Wang, Yun Luo, Ying Huang
BACKGROUND: The nuclear factor erythroid 2-related factor 2 (Nrf2) is a potential molecular target for cancer chemoprevention. Si-Wu-Tang (SWT), a popular traditional Chinese medicine for women's health, was reported with a novel activity of cancer prevention. PURPOSE: The present study was aimed to identify the bioactive constituents in SWT responsible for the Nrf2 activating and cancer preventive activity and explore the pharmacological mechanisms. METHODS: Nine compounds detectable from various batches of SWT were ranked using in silico molecular docking based on their ability to interfere the forming of Nrf2-Keap1 complex...
February 1, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29479956/comparison-of-standard-agglutination-tests-enzyme-immunoassay-and-coombs-gel-test-used-in-laboratory-diagnosis-of-human-brucellosis
#4
Emine Emel Koçman, Memnune Selda Erensoy, Meltem Taşbakan, Meltem Çiçeklioğlu
Background/aim: It was aimed to evaluate the results of Rose Bengal (RB), ELISA total tests (IgM and IgG), and the Brucella Coombs gel test (BCGT), which are used as screening tests, with the combined results of a tube agglutination test (standard Wright test: SWT) and a tube agglutination test with antihuman globulin (AHG TAT). Materials and methods: Samples from 97 patients prediagnosed with brucellosis (age ≥18 years) were screened with RB, ELISA, and BCGT. SWT < 160 samples and RB-negative but ELISA- or BCGT-positive samples were tested by AHG TAT...
February 23, 2018: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29317574/-role-of-immune-related-gtpase-m1-in-cortical-neurons-autophagy-of-mice-with-sepsis-induced-brain-injury
#5
Qun Huang, Bin Chen, Yafei Li, Xihong Li
To investigate the role of immune-related GTPase M1 (IRGM1) in cortical neurons autophagy in mice with sepsis induced brain injury (SIBI).
 Methods: Sixty wild-type C57BL/6 mice and sixty IRGM1 gene knockout C57BL/6 mice were randomly divided into 4 groups: a sham-operated wild-type (SWT) group, a cecal ligation and puncture (CLP) model wild-type (MWT) group, a sham-operated knockout (SKO) group, and a CLP model knockout (MKO) group. Models of mice with sepsis were established by CLP. Six hours of after CLP, the neurobehavioral scores for mice were recorded...
December 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29312775/case-report-improvement-of-cardiac-remodeling-with-shock-wave-therapy-of-a-patient-with-ischemic-cardiomyopathy
#6
Yingnan Bai, Xiaoyan Wang, Xin Deng, Hongyi Wu, Abdel Hamid Fathy, Yan Xi, Yunzeng Zou, Jie Cui, Junbo Ge
Percutaneous coronary intervention (PCI) and coronary-artery bypass grafting (CABG) are two major preferred reperfusion strategies to restore the ischemic-related artery patency, but PCI and CABG do not necessarily guarantee the recovery of post-procedure left ventricular (LV) dysfunction and release of symptoms. Moreover, there is no definitive effective way to enhance microcirculations. Theoretically, shock wave therapy (SWT) is an option. We report here a case of patient who received SWT. The patient's medical history was characterized by chest pain for 20 years, having received CABG 13 years ago...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29291535/detecting-atrial-fibrillation-by-deep-convolutional-neural-networks
#7
Yong Xia, Naren Wulan, Kuanquan Wang, Henggui Zhang
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia. The incidence of AF increases with age, causing high risks of stroke and increased morbidity and mortality. Efficient and accurate diagnosis of AF based on the ECG is valuable in clinical settings and remains challenging. In this paper, we proposed a novel method with high reliability and accuracy for AF detection via deep learning. METHOD: The short-term Fourier transform (STFT) and stationary wavelet transform (SWT) were used to analyze ECG segments to obtain two-dimensional (2-D) matrix input suitable for deep convolutional neural networks...
February 1, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29284454/the-effect-of-low-intensity-shockwave-treatment-li-swt-on-human-myoblasts-and-mouse-skeletal-muscle
#8
Lise K Hansen, Henrik D Schrøder, Lars Lund, Karthikeyan Rajagopal, Vrisha Maduri, Jeeva Sellathurai
BACKGROUND: Transplanting myogenic cells and scaffolds for tissue engineering in skeletal muscle have shown inconsistent results. One of the limiting factors is neovascularization at the recipient site. Low intensity shockwave therapy (Li-SWT) has been linked to increased tissue regeneration and vascularization, both integral to survival and integration of transplanted cells. This study was conducted to demonstrate the response of myoblasts and skeletal muscle to Li-SWT. METHOD: Primary isolated human myoblasts and explants were treated with low intensity shockwaves and subsequently cell viability, proliferation and differentiation were tested...
December 29, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29229555/reduced-cerebrovascular-reactivity-and-increased-resting-cerebral-perfusion-in-rats-exposed-to-a-cafeteria-diet
#9
Mariana Gomez-Smith, Rafal Janik, Conner Adams, Evelyn M Lake, Lynsie A M Thomason, Matthew S Jeffers, Bojana Stefanovic, Dale Corbett
To better understand the effects of a diet high in fat, sugar, and sodium on cerebrovascular function, Sprague Dawley rats were chronically exposed to a Cafeteria diet. Resting cerebral perfusion and cerebrovascular reactivity was quantified using continuous arterial spin labeling (CASL) magnetic resonance imaging (MRI). In addition, structural changes to the cerebrovasculature and susceptibility to ischemic lesion were examined. Compared to control animals fed standard chow (SD), Cafeteria diet (CAF) rats exhibited increased resting brain perfusion in the hippocampus and reduced cerebrovascular reactivity in response to 10% inspired CO2 challenges in both the hippocampus and the neocortex...
February 10, 2018: Neuroscience
https://www.readbyqxmd.com/read/29210958/reliability-and-validity-of-a-submaximal-warm-up-test-for-monitoring-training-status-in-professional-soccer-players
#10
Alireza Rabbani, Mehdi Kargarfard, Craig Twist
Rabbani, A, Kargarfard, M, and Twist, C. Reliability and validity of a submaximal warm-up test for monitoring training status in professional soccer players. J Strength Cond Res 32(2): 326-333, 2018-Two studies were conducted to assess the reliability and validity of a submaximal warm-up test (SWT) in professional soccer players. For the reliability study, 12 male players performed an SWT over 3 trials, with 1 week between trials. For the validity study, 14 players of the same team performed an SWT and a 30-15 intermittent fitness test (30-15IFT) 7 days apart...
February 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29121092/relationship-between-fine-particulate-matter-weather-condition-and-daily-non-accidental-mortality-in-shanghai-china-a-bayesian-approach
#11
Xin Fang, Bo Fang, Chunfang Wang, Tian Xia, Matteo Bottai, Fang Fang, Yang Cao
There are concerns that the reported association of ambient fine particulate matter (PM2.5) with mortality might be a mixture of PM2.5 and weather conditions. We evaluated the effects of extreme weather conditions and weather types on mortality as well as their interactions with PM2.5 concentrations in a time series study. Daily non-accidental deaths, individual demographic information, daily average PM2.5 concentrations and meteorological data between 2012 and 2014 were obtained from Shanghai, China. Days with extreme weather conditions were identified...
2017: PloS One
https://www.readbyqxmd.com/read/29098996/reliability-and-validity-of-an-audio-signal-modified-shuttle-walk-test
#12
Rupak Singla, Richa Rai, Abhishek Anil Faye, Anil Kumar Jain, Ranadip Chowdhury, Debdutta Bandyopadhyay
BACKGROUND: The audio signal in the conventionally accepted protocol of shuttle walk test (SWT) is not well-understood by the patients and modification of the audio signal may improve the performance of the test. OBJECTIVES: The aim of this study is to study the validity and reliability of an audio signal modified SWT, called the Singla-Richa modified SWT (SWTSR), in healthy normal adults. PATIENTS AND METHODS: In SWTSR, the audio signal was modified with the addition of reverse counting to it...
November 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/29052761/does-surgical-delay-for-radical-prostatectomy-affect-biochemical-recurrence-a-retrospective-analysis-from-a-canadian-cohort
#13
Marc Zanaty, Mansour Alnazari, Khaled Ajib, Kelsey Lawson, Mounsif Azizi, Emad Rajih, Abdullah Alenizi, Pierre-Alain Hueber, Côme Tolmier, Malek Meskawi, Fred Saad, Raisa S Pompe, Pierre I Karakiewicz, Assaad El-Hakim, Kevin C Zorn
AIM: We sought to explore the impact of surgical wait time (SWT) to robot-assisted radical prostatectomy (RARP) on biochemical recurrence (BCR). METHOD: Retrospective review of a prospectively collected database between 2006 and 2015 was conducted on all RARP cases. SWT was defined as period from prostate biopsy to surgery. Primary outcome was the impact on BCR, which was defined as two consecutive PSA ≥ 0.2 ng/dl, or salvage external beam radiation therapy and/or salvage androgen deprivation therapy...
January 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29031419/impact-of-surgical-waiting-time-on-survival-in-patients-with-upper-tract-urothelial-carcinoma-a-national-cancer-database-study
#14
Leilei Xia, Benjamin L Taylor, Jose E Pulido, Thomas J Guzzo
PURPOSE: To evaluate the impact of surgical waiting time (SWT) on the survival outcome in patients with upper tract urothelial carcinoma (UTUC). MATERIALS AND METHODS: We identified patients with nonmetastatic UTUC who underwent radical nephroureterectomy (RNU) between 2004 and 2013 in the National Cancer Database. The association between SWT and overall survival (OS) was evaluated using Cox proportional hazards regression. SWT was categorized into 6 groups: SWT ≤ 7 days, SWT 8 to 30 days, SWT 31 to 60 days, SWT 61 to 90 days, SWT 91 to 120 days, and SWT 121 to 180 days...
January 2018: Urologic Oncology
https://www.readbyqxmd.com/read/28872360/cardiorespiratory-fitness-and-walking-endurance-improvements-after-12-months-of-an-individualised-home-and-community-based-exercise-programme-for-people-after-stroke
#15
Ashlee Dunn, Dianne L Marsden, Daniel Barker, Paulette Van Vliet, Neil J Spratt, Robin Callister
OBJECTIVE: To evaluate the immediate and longer-term effects of an individually tailored, home- and community-based exercise programme with ongoing remote support in people with stroke on cardiorespiratory fitness (CRF), ambulation and health-related quality of life (HRQoL). METHODS: Twenty people 5.3 ± 3.5 months post stroke completed the 12-week HowFITSS? exercise programme aimed at increasing CRF and daily physical activity. Support was provided by phone and email, which decreased in frequency over time...
September 5, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28868151/motion-artefact-removals-for-wearable-ecg-using-stationary-wavelet-transform
#16
Shuto Nagai, Daisuke Anzai, Jianqing Wang
Wearable Electrocardiogram (ECG) is attracting much attention in daily healthcare applications. From the viewpoint of long-term use, it is desired that the electrodes are non-contact with the human body. In this study, the authors propose an algorithm using the stationary wavelet transform (SWT) to remove motion artefact superimposed on ECG signal when using non-contact capacitively coupling electrodes. The authors evaluate the effect on motion artefact removal of this algorithm by applying it to various ECG signals with motion artefacts superimposed...
August 2017: Healthcare Technology Letters
https://www.readbyqxmd.com/read/28858112/prescription-of-chinese-herbal-products-is-associated-with-a-decreased-risk-of-invasive-breast-cancer
#17
Yueh-Ting Tsai, Jung-Nien Lai, Pei-Chia Lo, Chin-Nu Chen, Jaung-Geng Lin
The finding of a decrease in endometrial cancer incidence among breast cancer survivors following the use of Chinese herbal products (CHPs) has led to speculation that CHPs might play a role in breast cancer prevention.This study provides an overview of breast cancer incidence, comparing CHP users with those who do not use traditional Chinese medicine (TCM), referred to as non-TCM users. The results can provide information to clinicians for counseling women about the preventive use of TCM.A total of 184,386 women (20-79 years of age) were recruited from a nationwide 1-million-person representative sample of those covered by National Health Insurance in Taiwan and were followed from 1999 to 2012...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28798829/does-surgical-delay-for-radical-prostatectomy-affect-patient-pathological-outcome-a-retrospective-analysis-from-a-canadian-cohort
#18
Marc Zanaty, Mansour Alnazari, Kelsey Lawson, Mounsif Azizi, Emad Rajih, Abdullah Alenizi, Pierre-Alain Hueber, Malek Meskawi, Cedric Lebacle, Thierry Lebeau, Serge Benayoun, Pierre I Karakiewicz, Assaad El-Hakim, Kevin C Zorn
INTRODUCTION: We sought to assess the impact of surgical wait time (SWT) to robot-assisted radical prostatectomy (RARP) on final pathological outcome. METHODS: A retrospective review of RARP patient records operated between 2006 and 2015 was conducted. SWT was defined as period from prostate biopsy to surgery. Primary outcome was the impact on postoperative Cancer of the Prostate Risk Assessment (CAPRA-S) score. Patients were stratified according to D'Amico risk categories...
August 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28782612/impact-of-the-removal-of-n-terminal-non-structured-amino-acids-on-activity-and-stability-of-xylanases-from-orpinomyces-sp-pc-2
#19
Rafaela Zandonade Ventorim, Tiago Antônio de Oliveira Mendes, Larissa Mattos Trevizano, Ana Maria Dos Santos Camargos, Valéria Monteze Guimarães
Xylanases catalyze the random hydrolysis of xylan backbone from plant biomass and thus, they have application in the production of biofuels, Kraft pulps biobleaching and feed industry. Here, xylanases derived from Orpinomyces sp. PC-2 were engineered guided by molecular dynamics methods to obtain more thermostable enzymes. Based on these models, 27 amino acid residues from the N-terminal were predicted to reduce protein stability and the impact of this removal was validated to two enzyme constructs: small xylanase Wild-Type (SWT) obtained from Wild-Type xylanase (WT) and small xylanase Mutant (SM2) generated from M2 mutant xylanase (V135A, A226T)...
January 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28772873/a-new-energy-critical-plane-damage-parameter-for-multiaxial-fatigue-life-prediction-of-turbine-blades
#20
Zheng-Yong Yu, Shun-Peng Zhu, Qiang Liu, Yunhan Liu
As one of fracture critical components of an aircraft engine, accurate life prediction of a turbine blade to disk attachment is significant for ensuring the engine structural integrity and reliability. Fatigue failure of a turbine blade is often caused under multiaxial cyclic loadings at high temperatures. In this paper, considering different failure types, a new energy-critical plane damage parameter is proposed for multiaxial fatigue life prediction, and no extra fitted material constants will be needed for practical applications...
May 8, 2017: Materials
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