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https://www.readbyqxmd.com/read/29752656/developmental-changes-in-oligodendrocyte-genesis-myelination-and-associated-behavioral-dysfunction-in-a-rat-model-of-intra-generational-protein-malnutrition
#1
Nisha Patro, Aijaz Ahmad Naik, Ishan K Patro
Impairments in oligodendrocyte development and resultant myelination deficits appear as a common denominator to all neurological diseases. An optimal in utero environment is obligatory for normal fetal brain development and later life brain functioning. Late embryonic and early postnatal brains from F1 rat born to protein malnourished mothers were studied through a combination of immunocytochemical and quantitative PCR assay for analyzing the relative expression of platelet-derived growth factor receptor-α (PDGFRα), myelin-associated glycoprotein (MAG), proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein (MOG) to determine oligodendrocyte genesis, differentiation, maturation, and myelination...
May 12, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29717496/evidence-for-paternal-kin-bias-in-the-social-affiliation-of-adult-female-blue-monkeys
#2
Marina Cords, Taylor Minich, Su-Jen Roberts, Clio Sleator
If animals increase inclusive fitness by cooperating with relatives, nepotism should involve maternal and paternal kin equally, all else being equal. Evidence of a behavioral bias toward paternal half-siblings in primates is both limited and mixed, with most positive reports from papionins. To expand knowledge of paternal kin recognition, particularly in cercopithecine monkeys, we examined evidence for paternal kin bias in wild blue monkeys (Cercopithecus mitis), a species living mostly in one-male groups. Seasonal breeding and the amount of male reproductive skew in blue monkeys suggests that opportunities to distinguish paternal kin are plentiful, and their social system would make such discrimination beneficial...
May 1, 2018: American Journal of Primatology
https://www.readbyqxmd.com/read/29715711/effects-of-fengliao-changweikang-in-diarrhea-predominant-irritable-bowel-syndrome-rats-and-its-mechanism-involving-colonic-motility
#3
Mengdi Jia, Xiaofang Lu, Luqing Zhao, Zhengfang Wang, Shengsheng Zhang
Background/Aims: This study was designed to investigate the effect of Fengliao-Changweikang (FLCWK) in diarrhea-predominant irritable bowel syndrome (IBS-D) rats and explore its underlying mechanisms. Methods: IBS-D model rats were induced by neonatal maternal separation (NMS) combined with restraint stress (RS). In in vivo experiments, the model rats were randomly divided into 5 groups: NMS + RS, FLCWK (low dose, middle dose, and high dose), and pinaverium bromide...
April 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29627348/the-acute-treatment-of-methemoglobinemia-in-pregnancy
#4
Nels Grauman Neander, Carly A Loner, Jason M Rotoli
BACKGROUND: Methemoglobinemia can be a potentially lethal condition due to the hypoxic stress placed on the body. In pregnancy, the deleterious effects can be even more catastrophic. The benefits of treatment in all patients, especially in those who are pregnant, must outweigh the inherent risks of the therapies used to treat methemoglobinemia. CASE REPORT: We present a case of a 26-year-old Hispanic pregnant female at 30 weeks gestation presenting to the emergency department for chest pain, hypoxia, and cyanosis...
April 4, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29615697/fathers-eye-colour-sways-daughters-choice-of-both-long-and-short-term-partners
#5
Paola Bressan, Valeria Damian
In several species, mate choice is influenced by parental features through sexual imprinting, but in humans evidence is scarce and open to alternative explanations. We examined whether daughters' preference for mates with light vs dark eyes is affected by the eye colour of parents. In an online study, over one thousand women rated the attractiveness of men as potential partners for either a long- or a short-term relationship. Each male face was shown twice, with light (blue or green) and with dark (brown or dark brown) eyes...
April 3, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29581742/methylene-blue-relieves-the-development-of-osteoarthritis-by-upregulating-lncrna-meg3
#6
Xinyi Li, Chaoliang Tang, Jin Wang, Peipei Guo, Chengyao Wang, Yanlin Wang, Zongze Zhang, Huisheng Wu
Methylene blue (MB) is a long-term inhibitor of peripheral nerve axons, thereby alleviating or permanently eliminating pain. However, it remains unknown whether MB is safe and effective method of treating osteoarthritis (OA). MB was injected into the knee joints of rabbits and they were monitored for any histological structural changes. The results revealed no evident changes in the histological structure of the normal knee joint following injection of 1 mg/kg MB at 1, 4, 8 and 24 weeks post-injection. Compared with the vehicle control, MB treatment significantly enhanced the weight distribution and significantly decreased the swelling ratio of the rabbits...
April 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29579410/dose-and-administration-protocol-for-fsh-used-for-ovarian-stimulation-affect-gene-expression-in-sheep-cumulus-oocyte-complexes
#7
Gláucia M Bragança, Ribrio Ivan T P Batista, Joanna Maria G Souza-Fabjan, Vivian A P Alfradique, Eduardo K N Arashiro, Isabel O Cosentino, Pedro Henrique N Pinto, Luiz Sérgio A Camargo, Jeferson F da Fonseca, Felipe Z Brandão
The present study evaluated the effect of four ovarian stimulation protocols on the follicular population and molecular status of cumulus-oocyte complexes (COCs). Twelve Santa Inês ewes (in a cross-over design) received 80 or 120mg FSH alone in a multiple-dose (MD80 and MD120) regimen or in combination with 300IU equine chorionic gonadotrophin (eCG) in a one-shot (OS80 and OS120) protocol. The follicular population, COC recovery rate, mean COCs per ewe and the rate of brilliant Cresyl blue-positive (BCB+) COCs were similar among treatments (P>0...
March 27, 2018: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/29528093/investigation-of-breastfeeding-training-based-on-basnef-model-on-the-intensity-of-postpartum-blues
#8
Marzieh Akbarzadeh, Sima Kiani Rad, Marzieh Moattari, Najaf Zare
Postpartum blues is a major risk factor for the incidence of postpartum depression and disruption of breastfeeding. This semi-experimental study investigated the effect of breastfeeding training based on the BASNEF model on severity of postpartum blues in 2012. Four educational sessions based on the BASNEF model were held separately for pregnant women and their mothers, mothers-in-law and spouses. The control group received routine care at the clinic. After delivery, women's knowledge of and attitude towards postpartum blues were evaluated using the Zung Self- Rating Depression Scale...
March 5, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29519542/point-of-care-fecal-calprotectin-monitoring-in-preterm-infants-at-risk-for-necrotizing-enterocolitis
#9
Warapan Nakayuenyongsuk, Megan Christofferson, David K Stevenson, Karl Sylvester, Henry C Lee, K T Park
OBJECTIVE: To establish baseline trends in fecal calprotectin, a protein excreted into the stool when there is neutrophilic inflammation in the bowel, in infants at risk for necrotizing enterocolitis (NEC). STUDY DESIGN: We performed a prospective observational cohort study in infants with a birth weight of <1500 g without existing bowel disease at a level IV neonatal intensive care unit from October 2015 to September 2016. Stools were collected once daily for 30 days or until 32 weeks postmenstrual age and processed using the Fecal Calprotectin High Range Quantitative Quantum Blue assay...
May 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29517361/the-effect-of-cognitive-behavioural-and-solution-focused-counselling-on-prevention-of-postpartum-depression-in-nulliparous-pregnant-women
#10
Somayeh Ramezani, Ahmad Khosravi, Zahra Motaghi, Azam Hamidzadeh, Seyed Abbas Mousavi
OBJECTIVE: The aim of this study was to evaluate the effect of cognitive-behavioural approach and solution-focused counselling on prevention of postpartum depression in nulliparous pregnant women. BACKGROUND: Maternity blues is a common disorder and postpartum depression is a serious disorder. Therefore, the use of preventive measures and timely intervention is of particular importance. METHODS: In this randomised clinical trial, 85 nulliparous pregnant women at 30-35 weeks were randomly divided into three groups: cognitive-behavioural counselling (n = 25), solution-focused counselling (n = 25) and control (n = 35)...
April 2017: Journal of Reproductive and Infant Psychology
https://www.readbyqxmd.com/read/29476434/complementary-medicines-in-pregnancy-recommendations-and-information-sources-of-healthcare-professionals-in-australia
#11
Christine E Gilmartin, To-Hao Vo-Tran, Laura Leung
Background The use of oral complementary and alternative medicines, including herbal supplements, has been increasing in pregnant women worldwide despite limited safety data. The decision of healthcare professionals to recommend these products to pregnant patients is controversial and not well documented. Objective To explore the recommendations and information sources that healthcare professionals use to determine the safety of oral non-prescribed supplements during pregnancy. Setting An Australian metropolitan maternity hospital...
April 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29317903/outbreak-of-pertussis-among-healthcare-workers-in-a-hospital-maternity-unit
#12
Christina Petridou, Hazel Gray, Michael Heard, Lorna Sugden, Karen Davis-Blues, Nick Cortes, Mary Edwards, Kordo Saeed
In December 2015, an outbreak of pertussis was detected among staff working in the Maternity Unit of a district general hospital in Hampshire. This occurred in the background of increased pertussis activity in the community. The outbreak occurred over the Christmas holiday period causing staff shortages at a time when the departments were already overstretched. The high prevalence of upper respiratory tract infections at the time were difficult to distinguish from pertussis. This paper describes the outbreak, infection control measures implemented and the learning points...
September 2017: Journal of Infection Prevention
https://www.readbyqxmd.com/read/29174273/placentophagy-s-effects-on-mood-bonding-and-fatigue-a-pilot-trial-part-2
#13
Sharon M Young, Laura K Gryder, Chad Cross, David Zava, David W Kimball, Daniel C Benyshek
BACKGROUND: Human maternal placentophagy is gaining popularity among a growing number of women who believe it provides maternal benefits, including prevention of postpartum blues/depression, improved maternal bonding, and reduced fatigue. METHODS: We conducted a randomized, double-blind, placebo-controlled pilot study (N=27) in which participants consumed either their processed, encapsulated placenta (n=12), or similarly prepared placebo (n=15). Maternal mood, bonding, and fatigue were assessed via validated scales across four time points during late pregnancy and early postpartum...
November 23, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29158937/connatal-urinary-ascites-in-a-female-preterm
#14
Barbara Brunner, Elisabeth Ralser, Elisabeth D'Costa, Kathrin Maurer, Ursula Kiechl-Kohlendorfer, Elke Griesmaier
Background: Connatal urinary ascites is rare in females without associated malformations and occurs following bladder rupture. Case Presentation: A female very preterm was delivered by caesarean section because of abnormal Doppler findings. The mother suffered from viral pneumonia requiring intensive care in the third trimester of pregnancy. Serial fetal ultrasound examinations showed a megacystis and ascites. Postnatally, pronounced isolated ascites was drained and its urinary nature was confirmed...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29130945/maternally-expressed-gene-3-meg3-enhances-pc12-cell-hypoxia-injury-by-targeting-mir-147
#15
Lili Han, Zhiling Dong, Ningning Liu, Fei Xie, Ning Wang
BACKGROUND/AIMS: Cerebral ischemia often leads to breakdown of blood-brain barrier (BBB) and vasogenic edema. It remains to be established whether MEG3 is responsible for the hypoxic damage in neural cells. This study aimed to investigate the role of MEG3 in the hypoxia-induced injuries of PC12 cells. METHODS: The PC12 cells were seeded and cultured under hypoxia and normoxia culture conditions. The cell viability determined by trypan blue exclusion, apoptosis using propidium iodide (PI) and fluorescein isothiocynate (FITC)-conjugated Annexin V staining, cell-migration using a modified two-chamber migration assay with a pore size of 8 µM and invasion using 24-well Millicell Hanging Cell Culture inserts with 8 µM PET membranes...
2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29044426/p2x7-receptor-blockade-prevents-preterm-birth-and-perinatal-brain-injury-in-a-mouse-model-of-intrauterine-inflammation
#16
Michael E Tsimis, Jun Lei, Jason M Rosenzweig, Hattan Arif, Yahya Shabi, Wael Alshehri, Connie C Talbot, K Maravet Baig-Ward, James Segars, Ernest M Graham, Irina Burd
The P2X7 is an adenosine triphosphate (ATP)-gated ion channel involved in several facets of immune activation and neuronal function through its importance in interleukin (IL)-1β secretion. We hypothesized that blockade of P2X7 would prevent perinatal brain injury associated with exposure to intrauterine (IU) inflammation. Dams received 45 mg/kg of Brilliant Blue G (BBG), a specific P2X7 receptor (P2X7R) antagonist, on gestation day 17 (E17) prior to administration of lipopolysaccharide (LPS) or phosphate-buffered saline (PBS)...
August 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28915896/placental-malaria-and-its-effect-on-pregnancy-outcomes-in-sudanese-women-from-blue-nile-state
#17
Samia A Omer, Hagir E Idress, Ishag Adam, Mutasim Abdelrahim, Ali N Noureldein, Abdelrahim M Abdelrazig, Mohammed O Elhassan, Suad M Sulaiman
BACKGROUND: Malaria infection during pregnancy can result in placental malaria and is associated with adverse pregnancy outcomes particularly among primigravidae. The aim of this study was to assess the prevalence and risk factors for placental malaria and its effect on pregnancy outcomes in Blue Nile state, Sudan. METHODS: A cross-sectional hospital-based study was conducted consecutively during January 2012-December 2015 in three main hospitals in Blue Nile State, Sudan...
September 16, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28803881/cell-specific-and-dose-dependent-effects-of-pahs-on-proliferation-cell-cycle-and-apoptosis-protein-expression-and-hormone-secretion-by-placental-cell-lines
#18
Eliza Drwal, Agnieszka Rak, Adam Grochowalski, Tomasz Milewicz, Ewa Lucja Gregoraszczuk
In the preset study we measured the concentrations of 16 priority PAHs in maternal blood and placental tissue by using the GC-MS/MS system, and investigated the effects of selected PAHs (naphthalene, anthracene, phenanthrene, pyrene) and mixtures on BeWo and JEG-3 human placental cell line proliferation (Alamar Blue), cytotoxicity (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (XTT), lactate dehydrogenase (LDH), acid phosphatase (AP), endocrine activity (progesterone and estradiol secretion) and apoptosis (cyclin A1, cyclin D2, cdk 2, cdk 4, Bcl-xl, Bax, and caspase-3 protein expression)...
October 5, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28760050/inside-out-the-role-of-anger-experience-and-expression-in-the-development-of-postpartum-mood-disorders
#19
Antonio Bruno, Antonio Simone Laganà, Valentina Leonardi, Domenica Greco, Marzia Merlino, Salvatore Giovanni Vitale, Onofrio Triolo, Rocco Antonio Zoccali, Maria Rosaria Anna Muscatello
PURPOSE: Among negative emotions, anger has not been studied in as much depth in her connection to postpartum mood disorders. The study aimed to investigate the role of anger as a potential vulnerability factor increasing the risk of Maternity Blues (MB) and Postpartum Depression (PPD). MATERIALS AND METHODS: Pregnant women in their third trimester of pregnancy underwent the following tests: the State Trait Anger Expression Inventory 2 - STAXI-2 (baseline visit), the Blues Questionnaire -BQ (3 and 5 days after delivery), and the Edinburgh Postnatal Depression Scale (EPDS) (3 and 6 months following delivery)...
August 11, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28731624/risk-for-postpartum-depression-among-immigrant-arabic-women-in-the-united-states-a-feasibility-study
#20
Dalia Alhasanat, Judith Fry-McComish, Hossein N Yarandi
INTRODUCTION: Postpartum depression (PPD) affects approximately 14% of women in the United States and 10% to 37% of Arabic women in the Middle East. Evidence suggests that immigrant women experience higher rates, but information on PPD among immigrant women of Arabic descent in the United States is nonexistent. METHODS: A cross-sectional descriptive feasibility study was conducted to assess the practicality of implementing a larger proposed research study to examine predictors of PPD in US immigrant women of Arabic descent residing in Dearborn, Michigan...
July 21, 2017: Journal of Midwifery & Women's Health
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